Explanation
This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are
presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.
"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.
miRNA-gene regulations
| Num | microRNA | Gene | miRNA log2FC | miRNA pvalue | Gene log2FC | Gene pvalue | Interaction | Correlation beta | Correlation P-value | PMID | Reported in cancer studies |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | hsa-miR-200c-3p | ABL2 | 0.38 | 0.08422 | 0.31 | 0.01567 | MirTarget | -0.14 | 0 | NA | |
| 2 | hsa-miR-200c-3p | ADAMTS3 | 0.38 | 0.08422 | -0.48 | 0.13892 | miRNATAP | -0.23 | 0.00061 | NA | |
| 3 | hsa-miR-200c-3p | ANKH | 0.38 | 0.08422 | 0 | 0.99073 | miRNATAP | -0.14 | 0.00072 | NA | |
| 4 | hsa-miR-200c-3p | ANLN | 0.38 | 0.08422 | 3.51 | 0 | MirTarget; miRNATAP | -0.18 | 0.02457 | NA | |
| 5 | hsa-miR-200c-3p | AP1S2 | 0.38 | 0.08422 | -1.29 | 0 | MirTarget; miRNATAP | -0.34 | 0 | NA | |
| 6 | hsa-miR-23a-3p | APAF1 | 0.11 | 0.39309 | 0.05 | 0.6283 | miRNATAP | -0.13 | 0.00069 | 24992592; 24249161 | Luciferase assay was performed to verify a putative target site of miR-23a in the 3'-UTR of apoptosis protease activating factor 1 APAF1 mRNA; The expression levels of miR-23a and APAF1 in CRC cell lines SW480 and SW620 and clinical samples were assessed using reverse transcription-quantitative real-time PCR RT-qPCR and Western blot; Moreover miR-23a up-regulation was coupled with APAF1 down-regulation in CRC tissue samples;We found that the expression of miR-23a was increased and the level of apoptosis-activating factor-1 APAF-1 was decreased in 5-FU-treated colon cancer cells compared to untreated cells; APAF-1 as a target gene of miR-23a was identified and miR-23a antisense-induced increase in the activation of caspase-9 was observed |
| 7 | hsa-miR-23b-3p | APAF1 | -0.07 | 0.62059 | 0.05 | 0.6283 | miRNATAP | -0.11 | 0.00216 | NA | |
| 8 | hsa-miR-27a-3p | APAF1 | 0.43 | 0.00737 | 0.05 | 0.6283 | miRNATAP | -0.16 | 0 | NA | |
| 9 | hsa-miR-27b-3p | APAF1 | 0.24 | 0.12264 | 0.05 | 0.6283 | miRNATAP | -0.17 | 0 | NA | |
| 10 | hsa-miR-664a-3p | APAF1 | 0.44 | 0.02142 | 0.05 | 0.6283 | mirMAP | -0.11 | 2.0E-5 | NA | |
| 11 | hsa-miR-200c-3p | ARHGAP18 | 0.38 | 0.08422 | -1.27 | 0 | MirTarget | -0.2 | 0 | NA | |
| 12 | hsa-miR-200c-3p | ARHGAP20 | 0.38 | 0.08422 | -1.06 | 0.00417 | MirTarget; miRNATAP | -0.42 | 0 | NA | |
| 13 | hsa-miR-200c-3p | ARHGAP28 | 0.38 | 0.08422 | -1.3 | 0 | MirTarget | -0.3 | 0 | NA | |
| 14 | hsa-miR-200c-3p | ARHGAP6 | 0.38 | 0.08422 | -2.71 | 0 | MirTarget | -0.2 | 0.00047 | NA | |
| 15 | hsa-miR-200c-3p | ARHGEF3 | 0.38 | 0.08422 | -0.99 | 0 | MirTarget | -0.12 | 1.0E-5 | NA | |
| 16 | hsa-miR-200c-3p | ARL10 | 0.38 | 0.08422 | -0.26 | 0.31668 | mirMAP | -0.3 | 0 | NA | |
| 17 | hsa-miR-200c-3p | ARL15 | 0.38 | 0.08422 | -0.77 | 0 | MirTarget | -0.1 | 0.00175 | NA | |
| 18 | hsa-miR-200c-3p | ASAP1 | 0.38 | 0.08422 | -0.4 | 0.01675 | MirTarget; miRNATAP | -0.2 | 0 | NA | |
| 19 | hsa-miR-200c-3p | ATP11C | 0.38 | 0.08422 | 0.13 | 0.44688 | MirTarget | -0.23 | 0 | NA | |
| 20 | hsa-miR-664a-5p | ATR | -0.09 | 0.66227 | 0.55 | 0 | mirMAP | -0.1 | 9.0E-5 | NA | |
| 21 | hsa-miR-200c-3p | ATXN1 | 0.38 | 0.08422 | -0.47 | 0.0003 | MirTarget; miRNATAP | -0.14 | 0 | NA | |
| 22 | hsa-miR-200c-3p | B4GALT6 | 0.38 | 0.08422 | -0.28 | 0.351 | MirTarget; miRNATAP | -0.19 | 0.00234 | NA | |
| 23 | hsa-miR-200c-3p | BACH2 | 0.38 | 0.08422 | -0.99 | 6.0E-5 | mirMAP | -0.19 | 0.00023 | NA | |
| 24 | hsa-miR-200c-3p | BAGE | 0.38 | 0.08422 | 0.6 | 0.19775 | MirTarget | -0.28 | 0.00491 | NA | |
| 25 | hsa-miR-143-3p | BBC3 | -1.21 | 1.0E-5 | 0.73 | 0.00024 | miRNATAP | -0.26 | 0 | NA | |
| 26 | hsa-miR-423-5p | BBC3 | -1.8 | 0 | 0.73 | 0.00024 | PITA | -0.19 | 2.0E-5 | NA | |
| 27 | hsa-miR-200c-3p | BCL11B | 0.38 | 0.08422 | 0.16 | 0.58729 | miRNATAP | -0.22 | 0.00048 | NA | |
| 28 | hsa-miR-200c-3p | BCL2 | 0.38 | 0.08422 | -0.49 | 0.06421 | miRNAWalker2 validate; miRTarBase; mirMAP | -0.13 | 0.02205 | NA | |
| 29 | hsa-miR-200c-3p | BEND4 | 0.38 | 0.08422 | -1.39 | 0.00124 | mirMAP | -0.38 | 3.0E-5 | NA | |
| 30 | hsa-miR-200c-3p | BHLHE41 | 0.38 | 0.08422 | -1.4 | 0 | MirTarget; miRNATAP | -0.41 | 0 | NA | |
| 31 | hsa-miR-200c-3p | BICD2 | 0.38 | 0.08422 | -0.64 | 0 | miRNATAP | -0.11 | 0 | NA | |
| 32 | hsa-miR-200c-3p | BNC2 | 0.38 | 0.08422 | -1.12 | 1.0E-5 | MirTarget | -0.53 | 0 | NA | |
| 33 | hsa-miR-200c-3p | C17orf51 | 0.38 | 0.08422 | -0.23 | 0.19564 | mirMAP | -0.15 | 5.0E-5 | NA | |
| 34 | hsa-miR-200c-3p | CACNA1C | 0.38 | 0.08422 | -1.13 | 2.0E-5 | MirTarget | -0.21 | 0.00011 | NA | |
| 35 | hsa-miR-200c-3p | CALU | 0.38 | 0.08422 | 0.7 | 3.0E-5 | MirTarget | -0.16 | 1.0E-5 | NA | |
| 36 | hsa-miR-200c-3p | CAMK1D | 0.38 | 0.08422 | 0.21 | 0.50334 | mirMAP | -0.21 | 0.00155 | NA | |
| 37 | hsa-miR-139-5p | CASP3 | -2.27 | 0 | 0.75 | 0 | miRanda | -0.1 | 0 | NA | |
| 38 | hsa-miR-195-3p | CASP3 | -1.33 | 0 | 0.75 | 0 | MirTarget | -0.12 | 0 | NA | |
| 39 | hsa-miR-30c-5p | CASP3 | -0.33 | 0.1236 | 0.75 | 0 | miRNATAP | -0.15 | 0 | NA | |
| 40 | hsa-miR-30d-5p | CASP3 | -0.92 | 4.0E-5 | 0.75 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.17 | 0 | NA | |
| 41 | hsa-miR-200c-3p | CBL | 0.38 | 0.08422 | -0.47 | 0.00116 | MirTarget; mirMAP | -0.17 | 0 | NA | |
| 42 | hsa-let-7b-5p | CCNB1 | -1.62 | 0 | 2.59 | 0 | miRNAWalker2 validate | -0.6 | 0 | NA | |
| 43 | hsa-miR-139-5p | CCNB1 | -2.27 | 0 | 2.59 | 0 | miRanda | -0.4 | 0 | NA | |
| 44 | hsa-let-7a-5p | CCNB2 | -1.37 | 0 | 3.05 | 0 | miRNAWalker2 validate | -0.57 | 0 | NA | |
| 45 | hsa-let-7b-5p | CCNB2 | -1.62 | 0 | 3.05 | 0 | miRNAWalker2 validate | -0.61 | 0 | NA | |
| 46 | hsa-let-7c-5p | CCNB2 | -2.14 | 0 | 3.05 | 0 | miRNAWalker2 validate | -0.62 | 0 | NA | |
| 47 | hsa-let-7f-5p | CCNB2 | -0.05 | 0.83408 | 3.05 | 0 | miRNAWalker2 validate | -0.14 | 0.01652 | NA | |
| 48 | hsa-miR-23b-3p | CCNB2 | -0.07 | 0.62059 | 3.05 | 0 | miRNAWalker2 validate | -0.6 | 0 | NA | |
| 49 | hsa-miR-106a-5p | CCND1 | 1.39 | 6.0E-5 | -0.3 | 0.2554 | MirTarget; miRNATAP | -0.25 | 0 | NA | |
| 50 | hsa-miR-106b-5p | CCND1 | 1.47 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.26 | 1.0E-5 | NA | |
| 51 | hsa-miR-142-3p | CCND1 | 3.98 | 0 | -0.3 | 0.2554 | miRanda | -0.12 | 0.00053 | 23619912 | Transfection of miR-142-3p mimics in colon cancer cells downregulated cyclin D1 expression induced G1 phase cell cycle arrest and elevated the sensitivity of the cells to 5-fluorouracil |
| 52 | hsa-miR-15a-5p | CCND1 | 1.63 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.2 | 0.00193 | 22922827 | CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR |
| 53 | hsa-miR-15b-5p | CCND1 | -1.26 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.3 | 0 | NA | |
| 54 | hsa-miR-16-1-3p | CCND1 | 1.5 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase | -0.25 | 3.0E-5 | 22922827; 18483394 | CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL |
| 55 | hsa-miR-16-5p | CCND1 | 0.75 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.37 | 0 | 23991964; 22922827; 18483394 | At the molecular level our results further revealed that cyclin D1 expression was negatively regulated by miR-16;CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL |
| 56 | hsa-miR-17-5p | CCND1 | 2.07 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP | -0.31 | 0 | 26431674 | Bioinformatics Prediction and In Vitro Analysis Revealed That miR 17 Targets Cyclin D1 mRNA in Triple Negative Breast Cancer Cells; In this study using bioinformatic analyses miR-17 was selected as it targets the 3'UTR of CCND1 gene with the highest score; After lentiviral transduction of miR-17 to the target cells gene expression analysis showed decreased expression of CCND1 gene |
| 57 | hsa-miR-183-5p | CCND1 | 2.39 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate | -0.11 | 0.01838 | NA | |
| 58 | hsa-miR-186-5p | CCND1 | 0.85 | 0 | -0.3 | 0.2554 | mirMAP | -0.38 | 1.0E-5 | NA | |
| 59 | hsa-miR-193a-3p | CCND1 | 0.55 | 0.0319 | -0.3 | 0.2554 | MirTarget; PITA; miRanda | -0.19 | 0.00016 | NA | |
| 60 | hsa-miR-193b-3p | CCND1 | 1.1 | 0.00082 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase; MirTarget | -0.15 | 4.0E-5 | 27071318; 20655737; 20304954; 21893020; 26129688 | MicroRNA 193b inhibits the proliferation migration and invasion of gastric cancer cells via targeting cyclin D1; Further mechanism study indicated that CCND1 was a direct target of miR-193b in GC;CCND1 and ETS1 were revealed to be regulated by miR-193b directly;MicroRNA 193b represses cell proliferation and regulates cyclin D1 in melanoma; Overexpression of miR-193b in Malme-3M cells down-regulated CCND1 mRNA and protein by > or = 50%; A luciferase reporter assay confirmed that miR-193b directly regulates CCND1 by binding to the 3'untranslated region of CCND1 mRNA; These studies indicate that miR-193b represses cell proliferation and regulates CCND1 expression and suggest that dysregulation of miR-193b may play an important role in melanoma development;In a previous study we reported that miR-193b represses cell proliferation and regulates cyclin D1 in melanoma cells suggesting that miR-193b could act as a tumor suppressor;Epigenetically altered miR 193b targets cyclin D1 in prostate cancer; It has been suggested that miR-193b targets cyclin D1 in several malignancies; Here our aim was to determine if miR-193b targets cyclin D1 in prostate cancer; Furthermore the PC cell lines 22Rv1 and VCaP which express low levels of miR-193b and high levels of CCND1 showed significant growth retardation when treated with a CDK4/6 inhibitor; In contrast the inhibitor had no effect on the growth of PC-3 and DU145 cells with high miR-193b and low CCND1 expression; Taken together our data demonstrate that miR-193b targets cyclin D1 in prostate cancer |
| 61 | hsa-miR-19a-3p | CCND1 | 2.12 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.22 | 0 | 25985117 | Moreover miR-19a might play inhibitory roles in HCC malignancy via regulating Cyclin D1 expression |
| 62 | hsa-miR-19b-1-5p | CCND1 | 1.71 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase | -0.3 | 0 | NA | |
| 63 | hsa-miR-19b-3p | CCND1 | 2.11 | 0 | -0.3 | 0.2554 | miRNATAP | -0.18 | 0.0002 | NA | |
| 64 | hsa-miR-20a-5p | CCND1 | 2.65 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.24 | 0 | NA | |
| 65 | hsa-miR-20b-5p | CCND1 | 1.36 | 0.00261 | -0.3 | 0.2554 | MirTarget; miRNATAP | -0.18 | 0 | NA | |
| 66 | hsa-miR-340-5p | CCND1 | -0.67 | 0.01861 | -0.3 | 0.2554 | mirMAP | -0.11 | 0.02446 | NA | |
| 67 | hsa-miR-365a-3p | CCND1 | 0.01 | 0.9536 | -0.3 | 0.2554 | miRNAWalker2 validate; miRTarBase | -0.19 | 0.00023 | NA | |
| 68 | hsa-miR-374a-5p | CCND1 | -0.2 | 0.29808 | -0.3 | 0.2554 | MirTarget | -0.31 | 1.0E-5 | 27191497 | microRNA 374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway; Furthermore luciferase reporter assays confirmed that miR-374a could directly reduce CCND1; We examined miR-374a levels by in situ hybridization and its correlation with CCND1 expression in CRC tumor tissues; High miR-374a expression with low level of CCND1 was protective factor in CRC; Together these findings indicate that miR-374a inactivates the PI3K/AKT axis by inhibiting CCND1 suppressing of colon cancer progression |
| 69 | hsa-miR-374b-5p | CCND1 | 0.47 | 0.01092 | -0.3 | 0.2554 | miRNAWalker2 validate; MirTarget | -0.26 | 0.00012 | NA | |
| 70 | hsa-miR-425-5p | CCND1 | 1.22 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate | -0.25 | 1.0E-5 | NA | |
| 71 | hsa-miR-589-3p | CCND1 | 1.34 | 2.0E-5 | -0.3 | 0.2554 | MirTarget | -0.13 | 0.00079 | NA | |
| 72 | hsa-miR-590-3p | CCND1 | 0.84 | 0.00129 | -0.3 | 0.2554 | mirMAP | -0.18 | 0.00086 | NA | |
| 73 | hsa-miR-7-1-3p | CCND1 | 2.61 | 0 | -0.3 | 0.2554 | mirMAP | -0.13 | 0.01795 | NA | |
| 74 | hsa-miR-769-3p | CCND1 | 0.45 | 0.07482 | -0.3 | 0.2554 | mirMAP | -0.14 | 0.00277 | NA | |
| 75 | hsa-miR-92a-3p | CCND1 | -0.14 | 0.49341 | -0.3 | 0.2554 | miRNAWalker2 validate | -0.34 | 0 | NA | |
| 76 | hsa-miR-93-5p | CCND1 | 1.51 | 0 | -0.3 | 0.2554 | miRNAWalker2 validate; MirTarget; miRNATAP | -0.32 | 0 | NA | |
| 77 | hsa-miR-942-5p | CCND1 | -0.04 | 0.87063 | -0.3 | 0.2554 | MirTarget | -0.18 | 0.00098 | NA | |
| 78 | hsa-miR-106a-5p | CCND2 | 1.39 | 6.0E-5 | -1.64 | 0 | miRNATAP | -0.15 | 2.0E-5 | NA | |
| 79 | hsa-miR-106b-5p | CCND2 | 1.47 | 0 | -1.64 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.38 | 0 | NA | |
| 80 | hsa-miR-130b-5p | CCND2 | 1.54 | 0 | -1.64 | 0 | mirMAP | -0.27 | 0 | NA | |
| 81 | hsa-miR-141-3p | CCND2 | 3.37 | 0 | -1.64 | 0 | MirTarget; TargetScan | -0.24 | 0 | NA | |
| 82 | hsa-miR-151a-3p | CCND2 | 0.67 | 0.00028 | -1.64 | 0 | mirMAP | -0.28 | 0 | NA | |
| 83 | hsa-miR-15a-5p | CCND2 | 1.63 | 0 | -1.64 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.16 | 0.00712 | NA | |
| 84 | hsa-miR-16-5p | CCND2 | 0.75 | 0 | -1.64 | 0 | miRNAWalker2 validate; miRNATAP | -0.14 | 0.04485 | NA | |
| 85 | hsa-miR-17-5p | CCND2 | 2.07 | 0 | -1.64 | 0 | miRNAWalker2 validate; miRTarBase; TargetScan; miRNATAP | -0.37 | 0 | NA | |
| 86 | hsa-miR-182-5p | CCND2 | 3.22 | 0 | -1.64 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.37 | 0 | NA | |
| 87 | hsa-miR-183-5p | CCND2 | 2.39 | 0 | -1.64 | 0 | miRNATAP | -0.41 | 0 | NA | |
| 88 | hsa-miR-185-5p | CCND2 | 1.14 | 0 | -1.64 | 0 | MirTarget; miRNATAP | -0.24 | 0.00048 | NA | |
| 89 | hsa-miR-186-5p | CCND2 | 0.85 | 0 | -1.64 | 0 | mirMAP; miRNATAP | -0.36 | 1.0E-5 | NA | |
| 90 | hsa-miR-191-5p | CCND2 | 0.34 | 0.06681 | -1.64 | 0 | MirTarget | -0.2 | 0.00075 | NA | |
| 91 | hsa-miR-19a-3p | CCND2 | 2.12 | 0 | -1.64 | 0 | MirTarget; miRNATAP | -0.17 | 1.0E-5 | NA | |
| 92 | hsa-miR-19b-3p | CCND2 | 2.11 | 0 | -1.64 | 0 | miRNAWalker2 validate; MirTarget; miRNATAP | -0.19 | 1.0E-5 | NA | |
| 93 | hsa-miR-200a-3p | CCND2 | 3.15 | 0 | -1.64 | 0 | MirTarget | -0.17 | 0 | NA | |
| 94 | hsa-miR-20a-5p | CCND2 | 2.65 | 0 | -1.64 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.28 | 0 | NA | |
| 95 | hsa-miR-21-3p | CCND2 | 2.54 | 0 | -1.64 | 0 | mirMAP | -0.21 | 0 | NA | |
| 96 | hsa-miR-2355-3p | CCND2 | 1.11 | 1.0E-5 | -1.64 | 0 | miRNATAP | -0.22 | 0 | NA | |
| 97 | hsa-miR-28-5p | CCND2 | 1.2 | 0 | -1.64 | 0 | miRanda | -0.29 | 0.00018 | NA | |
| 98 | hsa-miR-301a-3p | CCND2 | 2.7 | 0 | -1.64 | 0 | miRNAWalker2 validate | -0.27 | 0 | NA | |
| 99 | hsa-miR-320b | CCND2 | 0.23 | 0.37882 | -1.64 | 0 | mirMAP; miRNATAP | -0.12 | 0.00373 | NA | |
| 100 | hsa-miR-324-3p | CCND2 | -0.08 | 0.68923 | -1.64 | 0 | miRNAWalker2 validate | -0.28 | 0 | NA | |
| 101 | hsa-miR-331-5p | CCND2 | 0.58 | 0.00131 | -1.64 | 0 | miRNATAP | -0.28 | 1.0E-5 | NA | |
| 102 | hsa-miR-429 | CCND2 | 2.38 | 0 | -1.64 | 0 | miRNATAP | -0.21 | 0 | NA | |
| 103 | hsa-miR-450b-5p | CCND2 | 1.69 | 0 | -1.64 | 0 | MirTarget; PITA; miRNATAP | -0.15 | 9.0E-5 | NA | |
| 104 | hsa-miR-501-5p | CCND2 | 0.41 | 0.10435 | -1.64 | 0 | PITA; mirMAP; miRNATAP | -0.14 | 0.00086 | NA | |
| 105 | hsa-miR-503-5p | CCND2 | 1.97 | 0 | -1.64 | 0 | MirTarget | -0.13 | 5.0E-5 | 25860935 | We then identified two targets of miR-503 CCND2 and CCND3 |
| 106 | hsa-miR-550a-5p | CCND2 | 0.6 | 0.03148 | -1.64 | 0 | MirTarget | -0.22 | 0 | NA | |
| 107 | hsa-miR-589-3p | CCND2 | 1.34 | 2.0E-5 | -1.64 | 0 | mirMAP | -0.19 | 0 | NA | |
| 108 | hsa-miR-590-3p | CCND2 | 0.84 | 0.00129 | -1.64 | 0 | miRanda; mirMAP | -0.13 | 0.00821 | NA | |
| 109 | hsa-miR-590-5p | CCND2 | 2.07 | 0 | -1.64 | 0 | mirMAP | -0.26 | 0 | NA | |
| 110 | hsa-miR-660-5p | CCND2 | 2.05 | 0 | -1.64 | 0 | mirMAP | -0.15 | 0.00131 | NA | |
| 111 | hsa-miR-7-1-3p | CCND2 | 2.61 | 0 | -1.64 | 0 | mirMAP | -0.26 | 0 | NA | |
| 112 | hsa-miR-877-5p | CCND2 | -0.37 | 0.20671 | -1.64 | 0 | miRNAWalker2 validate | -0.15 | 6.0E-5 | NA | |
| 113 | hsa-miR-93-5p | CCND2 | 1.51 | 0 | -1.64 | 0 | miRNATAP | -0.41 | 0 | NA | |
| 114 | hsa-miR-96-5p | CCND2 | 3.04 | 0 | -1.64 | 0 | TargetScan; miRNATAP | -0.36 | 0 | NA | |
| 115 | hsa-miR-320b | CCND3 | 0.23 | 0.37882 | -0.86 | 1.0E-5 | miRanda | -0.11 | 0.00235 | NA | |
| 116 | hsa-miR-421 | CCND3 | 0.17 | 0.53528 | -0.86 | 1.0E-5 | PITA; miRanda | -0.12 | 0.00073 | NA | |
| 117 | hsa-miR-96-5p | CCND3 | 3.04 | 0 | -0.86 | 1.0E-5 | TargetScan | -0.12 | 0.00015 | NA | |
| 118 | hsa-miR-125b-5p | CCNE1 | -0.55 | 0.01072 | 3 | 0 | miRNAWalker2 validate | -0.21 | 0.00408 | NA | |
| 119 | hsa-miR-195-5p | CCNE1 | -1.02 | 5.0E-5 | 3 | 0 | miRNAWalker2 validate; MirTarget; miRNATAP | -0.52 | 0 | 24402230 | Furthermore through qPCR and western blot assays we showed that overexpression of miR-195-5p reduced CCNE1 mRNA and protein levels respectively |
| 120 | hsa-miR-26a-5p | CCNE1 | -0.13 | 0.44003 | 3 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.7 | 0 | 22094936 | Cell cycle regulation and CCNE1 and CDC2 were the only significant overlapping pathway and genes differentially expressed between tumors with high and low levels of miR-26a and EZH2 respectively; Low mRNA levels of EZH2 CCNE1 and CDC2 and high levels of miR-26a are associated with favorable outcome on tamoxifen |
| 121 | hsa-miR-497-5p | CCNE1 | -0.05 | 0.78621 | 3 | 0 | MirTarget; miRNATAP | -0.5 | 0 | 25909221; 24112607; 24909281 | The effect of simultaneous overexpression of miR-497 and miR-34a on the inhibition of cell proliferation colony formation and tumor growth and the downregulation of cyclin E1 was stronger than the effect of each miRNA alone; The synergistic actions of miR-497 and miR-34a partly correlated with cyclin E1 levels; These results indicate cyclin E1 is downregulated by both miR-497 and miR-34a which synergistically retard the growth of human lung cancer cells;Western blot assays confirmed that overexpression of miR-497 reduced cyclin E1 protein levels; Inhibited cellular growth suppressed cellular migration and invasion and G1 cell cycle arrest were observed upon overexpression of miR-497 in cells possibly by targeting cyclin E1;miR 497 suppresses proliferation of human cervical carcinoma HeLa cells by targeting cyclin E1; Furthermore the target effect of miR-497 on the CCNE1 was identified by dual-luciferase reporter assay system qRT-PCR and Western blotting; Over-expressed miR-497 in HeLa cells could suppress cell proliferation by targeting CCNE1 |
| 122 | hsa-let-7a-3p | CCNE2 | 0.17 | 0.43183 | 2.15 | 0 | mirMAP | -0.22 | 0.00307 | NA | |
| 123 | hsa-let-7b-3p | CCNE2 | -1.82 | 0 | 2.15 | 0 | mirMAP | -0.49 | 0 | NA | |
| 124 | hsa-let-7f-1-3p | CCNE2 | -0.09 | 0.69397 | 2.15 | 0 | mirMAP | -0.16 | 0.0281 | NA | |
| 125 | hsa-miR-126-3p | CCNE2 | 0.4 | 0.11564 | 2.15 | 0 | miRNAWalker2 validate | -0.15 | 0.00656 | NA | |
| 126 | hsa-miR-140-5p | CCNE2 | 0.67 | 0.00034 | 2.15 | 0 | miRanda | -0.17 | 0.02593 | NA | |
| 127 | hsa-miR-26a-5p | CCNE2 | -0.13 | 0.44003 | 2.15 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.51 | 0 | 24116110; 21901171 | The loss of miR 26a mediated post transcriptional regulation of cyclin E2 in pancreatic cancer cell proliferation and decreased patient survival; The in vitro and in vivo assays showed that overexpression of miR-26a resulted in cell cycle arrest inhibited cell proliferation and decreased tumor growth which was associated with cyclin E2 downregulation;We also show that enforced expression of miR-26a in AML cells is able to inhibit cell cycle progression by downregulating cyclin E2 expression |
| 128 | hsa-miR-26b-5p | CCNE2 | 0.72 | 5.0E-5 | 2.15 | 0 | miRNATAP | -0.22 | 0.00477 | NA | |
| 129 | hsa-miR-3065-5p | CCNE2 | 0.65 | 0.09995 | 2.15 | 0 | mirMAP | -0.2 | 0 | NA | |
| 130 | hsa-miR-30a-5p | CCNE2 | -0.92 | 0.00076 | 2.15 | 0 | miRNATAP | -0.49 | 0 | NA | |
| 131 | hsa-miR-30b-5p | CCNE2 | 0.36 | 0.13803 | 2.15 | 0 | miRNAWalker2 validate; miRTarBase | -0.2 | 0.0005 | 22384020 | A luciferase-based reporter assay demonstrated that miR-30b post-transcriptionally reduced 27% p = 0.005 of the gene expression by interacting with two binding sites in the 3'-UTR of CCNE2; The upregulation of miR-30b by trastuzumab may play a biological role in trastuzumab-induced cell growth inhibition by targeting CCNE2 |
| 132 | hsa-miR-30c-5p | CCNE2 | -0.33 | 0.1236 | 2.15 | 0 | miRNATAP | -0.44 | 0 | NA | |
| 133 | hsa-miR-30d-5p | CCNE2 | -0.92 | 4.0E-5 | 2.15 | 0 | miRNATAP | -0.35 | 0 | 25843294 | MicroRNA 30d 5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non small cell lung cancer; In addition the re-introduction of CCNE2 expression antagonised the inhibitory effects of miR-30d-5p on the capacity of NSCLC cells for proliferation and motility |
| 134 | hsa-miR-34a-5p | CCNE2 | 1.41 | 0 | 2.15 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.2 | 0.00337 | NA | |
| 135 | hsa-miR-34c-5p | CCNE2 | -1 | 0.07244 | 2.15 | 0 | miRNAWalker2 validate; miRTarBase; PITA; miRanda; miRNATAP | -0.11 | 4.0E-5 | NA | |
| 136 | hsa-miR-514a-3p | CCNE2 | -0.62 | 0.31374 | 2.15 | 0 | miRNATAP | -0.17 | 0 | NA | |
| 137 | hsa-miR-532-3p | CCNE2 | -0.68 | 0.01476 | 2.15 | 0 | PITA | -0.1 | 0.04553 | NA | |
| 138 | hsa-miR-132-3p | CCNG1 | 0.01 | 0.93403 | -0.38 | 0.02147 | MirTarget | -0.16 | 0.00185 | NA | |
| 139 | hsa-miR-197-3p | CCNG1 | -1.3 | 0 | -0.38 | 0.02147 | miRNAWalker2 validate | -0.12 | 6.0E-5 | NA | |
| 140 | hsa-miR-21-5p | CCNG1 | 4.38 | 0 | -0.38 | 0.02147 | miRNAWalker2 validate | -0.13 | 1.0E-5 | NA | |
| 141 | hsa-miR-23a-3p | CCNG1 | 0.11 | 0.39309 | -0.38 | 0.02147 | MirTarget; miRNATAP | -0.18 | 0.00203 | NA | |
| 142 | hsa-miR-24-3p | CCNG1 | -0.04 | 0.78587 | -0.38 | 0.02147 | miRNAWalker2 validate | -0.14 | 0.01958 | NA | |
| 143 | hsa-miR-27a-3p | CCNG1 | 0.43 | 0.00737 | -0.38 | 0.02147 | MirTarget; miRNATAP | -0.25 | 0 | NA | |
| 144 | hsa-miR-27b-3p | CCNG1 | 0.24 | 0.12264 | -0.38 | 0.02147 | MirTarget; miRNATAP | -0.17 | 0.00064 | 26623719 | Moreover miR-27b directly targets the 3' untranslated regions 3'-UTRs of CCNG1 a well-known negative regulator of P53 stability; Interestingly miR-27b up-regulation leads to increased miR-508-5p expression and this phenomenon is mediated by CCNG1 and P53 |
| 145 | hsa-miR-339-5p | CCNG1 | 0.54 | 0.04881 | -0.38 | 0.02147 | miRanda | -0.15 | 0 | NA | |
| 146 | hsa-miR-590-5p | CCNG1 | 2.07 | 0 | -0.38 | 0.02147 | miRanda | -0.19 | 0 | NA | |
| 147 | hsa-miR-96-5p | CCNG1 | 3.04 | 0 | -0.38 | 0.02147 | MirTarget; TargetScan | -0.13 | 1.0E-5 | NA | |
| 148 | hsa-miR-195-3p | CCNG2 | -1.33 | 0 | 0.22 | 0.10548 | mirMAP | -0.1 | 0.00014 | NA | |
| 149 | hsa-miR-365a-3p | CCNG2 | 0.01 | 0.9536 | 0.22 | 0.10548 | MirTarget | -0.11 | 3.0E-5 | NA | |
| 150 | hsa-miR-374a-5p | CCNG2 | -0.2 | 0.29808 | 0.22 | 0.10548 | mirMAP | -0.14 | 0.00021 | NA |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT | 75 | 1672 | 1.848e-17 | 8.6e-14 |
| 2 | POSITIVE REGULATION OF CATALYTIC ACTIVITY | 70 | 1518 | 6.901e-17 | 1.605e-13 |
| 3 | POSITIVE REGULATION OF MOLECULAR FUNCTION | 76 | 1791 | 2.326e-16 | 3.608e-13 |
| 4 | REGULATION OF CELL PROLIFERATION | 65 | 1496 | 1.947e-14 | 2.265e-11 |
| 5 | REGULATION OF CELLULAR COMPONENT MOVEMENT | 44 | 771 | 7.245e-14 | 6.742e-11 |
| 6 | REGULATION OF CELL DIFFERENTIATION | 63 | 1492 | 1.953e-13 | 1.515e-10 |
| 7 | REGULATION OF KINASE ACTIVITY | 43 | 776 | 3.899e-13 | 2.454e-10 |
| 8 | TISSUE DEVELOPMENT | 63 | 1518 | 4.219e-13 | 2.454e-10 |
| 9 | POSITIVE REGULATION OF DEVELOPMENTAL PROCESS | 53 | 1142 | 6.214e-13 | 3.213e-10 |
| 10 | POSITIVE REGULATION OF HYDROLASE ACTIVITY | 46 | 905 | 1.146e-12 | 5.33e-10 |
| 11 | INTRACELLULAR SIGNAL TRANSDUCTION | 63 | 1572 | 1.963e-12 | 8.306e-10 |
| 12 | REGULATION OF CELL DEATH | 60 | 1472 | 3.672e-12 | 1.424e-09 |
| 13 | REGULATION OF HYDROLASE ACTIVITY | 55 | 1327 | 1.833e-11 | 6.339e-09 |
| 14 | REGULATION OF TRANSFERASE ACTIVITY | 45 | 946 | 1.943e-11 | 6.339e-09 |
| 15 | REGULATION OF PHOSPHORUS METABOLIC PROCESS | 62 | 1618 | 2.043e-11 | 6.339e-09 |
| 16 | RESPONSE TO ABIOTIC STIMULUS | 46 | 1024 | 7.703e-11 | 2.24e-08 |
| 17 | CELL DEVELOPMENT | 56 | 1426 | 9.287e-11 | 2.542e-08 |
| 18 | MOVEMENT OF CELL OR SUBCELLULAR COMPONENT | 52 | 1275 | 1.283e-10 | 3.316e-08 |
| 19 | REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION | 61 | 1656 | 1.529e-10 | 3.745e-08 |
| 20 | REGULATION OF PROTEIN MODIFICATION PROCESS | 62 | 1710 | 1.984e-10 | 4.615e-08 |
| 21 | EPITHELIUM DEVELOPMENT | 43 | 945 | 2.32e-10 | 5.14e-08 |
| 22 | RESPONSE TO WOUNDING | 32 | 563 | 2.66e-10 | 5.38e-08 |
| 23 | REGULATION OF CELL CYCLE | 43 | 949 | 2.645e-10 | 5.38e-08 |
| 24 | REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 29 | 470 | 2.897e-10 | 5.616e-08 |
| 25 | POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION | 48 | 1152 | 3.631e-10 | 6.758e-08 |
| 26 | NEGATIVE REGULATION OF CELL PROLIFERATION | 34 | 643 | 4.743e-10 | 8.488e-08 |
| 27 | RESPONSE TO OXYGEN LEVELS | 23 | 311 | 6.909e-10 | 1.191e-07 |
| 28 | REGULATION OF NEURON DIFFERENTIATION | 31 | 554 | 7.529e-10 | 1.251e-07 |
| 29 | NEGATIVE REGULATION OF CELL CYCLE | 27 | 433 | 9.758e-10 | 1.566e-07 |
| 30 | POSITIVE REGULATION OF RESPONSE TO STIMULUS | 65 | 1929 | 1.35e-09 | 2.026e-07 |
| 31 | POSITIVE REGULATION OF CELL COMMUNICATION | 56 | 1532 | 1.34e-09 | 2.026e-07 |
| 32 | POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS | 55 | 1492 | 1.432e-09 | 2.082e-07 |
| 33 | POSITIVE REGULATION OF CELL DIFFERENTIATION | 38 | 823 | 1.927e-09 | 2.717e-07 |
| 34 | NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION | 13 | 98 | 3.83e-09 | 5.242e-07 |
| 35 | REGULATION OF CELL ADHESION | 32 | 629 | 4.075e-09 | 5.418e-07 |
| 36 | CARDIOVASCULAR SYSTEM DEVELOPMENT | 36 | 788 | 7.031e-09 | 8.842e-07 |
| 37 | CIRCULATORY SYSTEM DEVELOPMENT | 36 | 788 | 7.031e-09 | 8.842e-07 |
| 38 | REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS | 42 | 1021 | 7.637e-09 | 9.351e-07 |
| 39 | POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS | 51 | 1395 | 8.298e-09 | 9.9e-07 |
| 40 | REGULATION OF CELL DEVELOPMENT | 37 | 836 | 9.875e-09 | 1.149e-06 |
| 41 | RESPONSE TO ENDOGENOUS STIMULUS | 52 | 1450 | 1.099e-08 | 1.248e-06 |
| 42 | POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS | 42 | 1036 | 1.161e-08 | 1.257e-06 |
| 43 | POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS | 42 | 1036 | 1.161e-08 | 1.257e-06 |
| 44 | REGULATION OF CELL MATRIX ADHESION | 12 | 90 | 1.448e-08 | 1.531e-06 |
| 45 | RESPONSE TO STEROID HORMONE | 27 | 497 | 1.846e-08 | 1.909e-06 |
| 46 | REGULATION OF EPITHELIAL CELL PROLIFERATION | 20 | 285 | 2.232e-08 | 2.214e-06 |
| 47 | POSITIVE REGULATION OF CELL DEATH | 30 | 605 | 2.284e-08 | 2.214e-06 |
| 48 | VASCULATURE DEVELOPMENT | 26 | 469 | 2.28e-08 | 2.214e-06 |
| 49 | NEUROGENESIS | 50 | 1402 | 2.639e-08 | 2.506e-06 |
| 50 | LOCOMOTION | 43 | 1114 | 3.148e-08 | 2.929e-06 |
| 51 | POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION | 37 | 876 | 3.326e-08 | 3.035e-06 |
| 52 | RESPONSE TO ORGANIC CYCLIC COMPOUND | 38 | 917 | 3.517e-08 | 3.096e-06 |
| 53 | SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION | 22 | 352 | 3.527e-08 | 3.096e-06 |
| 54 | BLOOD VESSEL MORPHOGENESIS | 22 | 364 | 6.379e-08 | 5.497e-06 |
| 55 | CELLULAR COMPONENT MORPHOGENESIS | 37 | 900 | 6.627e-08 | 5.606e-06 |
| 56 | REGULATION OF NERVOUS SYSTEM DEVELOPMENT | 33 | 750 | 7.586e-08 | 6.303e-06 |
| 57 | REGULATION OF CELL SUBSTRATE ADHESION | 15 | 173 | 8.62e-08 | 7.037e-06 |
| 58 | NEGATIVE REGULATION OF CELL DEATH | 36 | 872 | 9.137e-08 | 7.205e-06 |
| 59 | BIOLOGICAL ADHESION | 40 | 1032 | 9.015e-08 | 7.205e-06 |
| 60 | WOUND HEALING | 25 | 470 | 9.522e-08 | 7.384e-06 |
| 61 | POSITIVE REGULATION OF GENE EXPRESSION | 56 | 1733 | 9.961e-08 | 7.598e-06 |
| 62 | POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS | 42 | 1135 | 1.482e-07 | 1.112e-05 |
| 63 | POSITIVE REGULATION OF KINASE ACTIVITY | 25 | 482 | 1.538e-07 | 1.136e-05 |
| 64 | REGULATION OF TRANSPORT | 57 | 1804 | 1.594e-07 | 1.159e-05 |
| 65 | RESPONSE TO HORMONE | 36 | 893 | 1.637e-07 | 1.172e-05 |
| 66 | CELL JUNCTION ORGANIZATION | 15 | 185 | 2.08e-07 | 1.466e-05 |
| 67 | REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER | 56 | 1784 | 2.596e-07 | 1.803e-05 |
| 68 | RESPONSE TO METAL ION | 20 | 333 | 2.84e-07 | 1.944e-05 |
| 69 | NEGATIVE REGULATION OF CELL MATRIX ADHESION | 7 | 30 | 3.012e-07 | 2.031e-05 |
| 70 | REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 11 | 97 | 3.164e-07 | 2.103e-05 |
| 71 | ORGAN MORPHOGENESIS | 34 | 841 | 3.479e-07 | 2.28e-05 |
| 72 | RAS PROTEIN SIGNAL TRANSDUCTION | 13 | 143 | 3.659e-07 | 2.365e-05 |
| 73 | RESPONSE TO LIPID | 35 | 888 | 4.193e-07 | 2.673e-05 |
| 74 | NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION | 13 | 146 | 4.653e-07 | 2.926e-05 |
| 75 | REGULATION OF MAPK CASCADE | 29 | 660 | 5.04e-07 | 3.046e-05 |
| 76 | REGULATION OF CELL CYCLE G1 S PHASE TRANSITION | 13 | 147 | 5.034e-07 | 3.046e-05 |
| 77 | CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION | 25 | 513 | 4.929e-07 | 3.046e-05 |
| 78 | NEGATIVE REGULATION OF MITOTIC CELL CYCLE | 15 | 199 | 5.334e-07 | 3.182e-05 |
| 79 | REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT | 8 | 48 | 6.702e-07 | 3.85e-05 |
| 80 | APOPTOTIC SIGNALING PATHWAY | 18 | 289 | 6.676e-07 | 3.85e-05 |
| 81 | POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 18 | 289 | 6.676e-07 | 3.85e-05 |
| 82 | SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 12 | 127 | 6.821e-07 | 3.871e-05 |
| 83 | RESPONSE TO OXYGEN CONTAINING COMPOUND | 46 | 1381 | 7.235e-07 | 4.056e-05 |
| 84 | INTRINSIC APOPTOTIC SIGNALING PATHWAY | 13 | 152 | 7.392e-07 | 4.095e-05 |
| 85 | NEGATIVE REGULATION OF PHOSPHORYLATION | 22 | 422 | 8.038e-07 | 4.4e-05 |
| 86 | ANGIOGENESIS | 18 | 293 | 8.148e-07 | 4.409e-05 |
| 87 | POSITIVE REGULATION OF BIOSYNTHETIC PROCESS | 55 | 1805 | 8.688e-07 | 4.645e-05 |
| 88 | REGULATION OF CHEMOTAXIS | 14 | 180 | 8.785e-07 | 4.645e-05 |
| 89 | EPITHELIAL CELL DIFFERENTIATION | 24 | 495 | 9.199e-07 | 4.81e-05 |
| 90 | REGULATION OF CELL CYCLE ARREST | 11 | 108 | 9.434e-07 | 4.877e-05 |
| 91 | RESPONSE TO ALCOHOL | 20 | 362 | 1.056e-06 | 5.343e-05 |
| 92 | RESPONSE TO MECHANICAL STIMULUS | 15 | 210 | 1.056e-06 | 5.343e-05 |
| 93 | RESPONSE TO DRUG | 22 | 431 | 1.141e-06 | 5.709e-05 |
| 94 | CELL CYCLE G1 S PHASE TRANSITION | 11 | 111 | 1.242e-06 | 6.083e-05 |
| 95 | G1 S TRANSITION OF MITOTIC CELL CYCLE | 11 | 111 | 1.242e-06 | 6.083e-05 |
| 96 | POSITIVE REGULATION OF MAPK CASCADE | 23 | 470 | 1.334e-06 | 6.359e-05 |
| 97 | NEGATIVE REGULATION OF CELL CYCLE PROCESS | 15 | 214 | 1.339e-06 | 6.359e-05 |
| 98 | POSITIVE REGULATION OF TRANSFERASE ACTIVITY | 27 | 616 | 1.331e-06 | 6.359e-05 |
| 99 | EXTRACELLULAR STRUCTURE ORGANIZATION | 18 | 304 | 1.384e-06 | 6.505e-05 |
| 100 | NEGATIVE REGULATION OF CELL COMMUNICATION | 41 | 1192 | 1.404e-06 | 6.534e-05 |
| 101 | NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION | 8 | 53 | 1.472e-06 | 6.781e-05 |
| 102 | RESPONSE TO ESTROGEN | 15 | 218 | 1.688e-06 | 7.702e-05 |
| 103 | RESPONSE TO INORGANIC SUBSTANCE | 23 | 479 | 1.84e-06 | 8.31e-05 |
| 104 | G1 DNA DAMAGE CHECKPOINT | 9 | 73 | 1.871e-06 | 8.369e-05 |
| 105 | NEGATIVE REGULATION OF CELL ADHESION | 15 | 223 | 2.239e-06 | 9.92e-05 |
| 106 | ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS | 35 | 957 | 2.32e-06 | 9.994e-05 |
| 107 | ACTIN FILAMENT BASED PROCESS | 22 | 450 | 2.315e-06 | 9.994e-05 |
| 108 | REGULATION OF GTPASE ACTIVITY | 28 | 673 | 2.316e-06 | 9.994e-05 |
| 109 | CELL MOTILITY | 32 | 835 | 2.464e-06 | 0.0001042 |
| 110 | LOCALIZATION OF CELL | 32 | 835 | 2.464e-06 | 0.0001042 |
| 111 | CELL CYCLE PHASE TRANSITION | 16 | 255 | 2.55e-06 | 0.0001069 |
| 112 | REGULATION OF ORGANELLE ORGANIZATION | 40 | 1178 | 2.624e-06 | 0.000109 |
| 113 | NEGATIVE REGULATION OF RESPONSE TO STIMULUS | 44 | 1360 | 2.797e-06 | 0.0001152 |
| 114 | REGULATION OF CELL CYCLE PHASE TRANSITION | 18 | 321 | 2.99e-06 | 0.000122 |
| 115 | TISSUE MORPHOGENESIS | 24 | 533 | 3.327e-06 | 0.0001346 |
| 116 | TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY | 23 | 498 | 3.524e-06 | 0.0001414 |
| 117 | ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY | 28 | 689 | 3.625e-06 | 0.0001442 |
| 118 | REGULATION OF DNA DAMAGE RESPONSE SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 6 | 28 | 3.734e-06 | 0.0001472 |
| 119 | NEGATIVE REGULATION OF LOCOMOTION | 16 | 263 | 3.796e-06 | 0.0001484 |
| 120 | RESPONSE TO CORTICOSTEROID | 13 | 176 | 3.841e-06 | 0.0001489 |
| 121 | CELLULAR RESPONSE TO ORGANIC SUBSTANCE | 54 | 1848 | 3.924e-06 | 0.0001509 |
| 122 | CELLULAR RESPONSE TO EXTERNAL STIMULUS | 16 | 264 | 3.985e-06 | 0.000152 |
| 123 | NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS | 35 | 983 | 4.2e-06 | 0.0001589 |
| 124 | NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS | 24 | 541 | 4.288e-06 | 0.0001596 |
| 125 | NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS | 24 | 541 | 4.288e-06 | 0.0001596 |
| 126 | REGULATION OF MITOTIC CELL CYCLE | 22 | 468 | 4.354e-06 | 0.0001608 |
| 127 | RESPONSE TO NITROGEN COMPOUND | 32 | 859 | 4.442e-06 | 0.0001628 |
| 128 | REGULATION OF MUSCLE TISSUE DEVELOPMENT | 10 | 103 | 4.576e-06 | 0.0001651 |
| 129 | REGULATION OF MUSCLE ORGAN DEVELOPMENT | 10 | 103 | 4.576e-06 | 0.0001651 |
| 130 | REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION | 6 | 29 | 4.647e-06 | 0.0001663 |
| 131 | POSITIVE REGULATION OF CELL DEVELOPMENT | 22 | 472 | 4.987e-06 | 0.0001771 |
| 132 | POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT | 21 | 437 | 5.148e-06 | 0.0001815 |
| 133 | CELL JUNCTION ASSEMBLY | 11 | 129 | 5.455e-06 | 0.0001908 |
| 134 | POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION | 17 | 303 | 5.601e-06 | 0.0001945 |
| 135 | CELL DEATH | 35 | 1001 | 6.239e-06 | 0.000215 |
| 136 | POSITIVE REGULATION OF NEURON DIFFERENTIATION | 17 | 306 | 6.38e-06 | 0.0002183 |
| 137 | REGULATION OF GROWTH | 26 | 633 | 6.776e-06 | 0.0002252 |
| 138 | CELL CYCLE | 42 | 1316 | 6.767e-06 | 0.0002252 |
| 139 | POSITIVE REGULATION OF CELL CYCLE ARREST | 9 | 85 | 6.743e-06 | 0.0002252 |
| 140 | POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER | 35 | 1004 | 6.657e-06 | 0.0002252 |
| 141 | REGULATION OF CELL PROJECTION ORGANIZATION | 24 | 558 | 7.221e-06 | 0.0002383 |
| 142 | REGULATION OF MEMBRANE POTENTIAL | 18 | 343 | 7.49e-06 | 0.0002454 |
| 143 | NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS | 30 | 801 | 8.099e-06 | 0.0002635 |
| 144 | REGULATION OF ACTIN FILAMENT BASED PROCESS | 17 | 312 | 8.238e-06 | 0.0002662 |
| 145 | MITOTIC CELL CYCLE | 29 | 766 | 9.427e-06 | 0.0003004 |
| 146 | RESPONSE TO REACTIVE OXYGEN SPECIES | 13 | 191 | 9.379e-06 | 0.0003004 |
| 147 | POSITIVE REGULATION OF LOCOMOTION | 20 | 420 | 9.897e-06 | 0.0003112 |
| 148 | POSITIVE REGULATION OF TRANSPORT | 33 | 936 | 9.868e-06 | 0.0003112 |
| 149 | REGULATION OF CELL JUNCTION ASSEMBLY | 8 | 68 | 1.004e-05 | 0.0003114 |
| 150 | EMBRYO DEVELOPMENT | 32 | 894 | 1.002e-05 | 0.0003114 |
| 151 | REGULATION OF CELLULAR RESPONSE TO STRESS | 27 | 691 | 1.108e-05 | 0.0003396 |
| 152 | CELL CYCLE CHECKPOINT | 13 | 194 | 1.109e-05 | 0.0003396 |
| 153 | POSITIVE REGULATION OF ORGANELLE ORGANIZATION | 24 | 573 | 1.122e-05 | 0.0003412 |
| 154 | REGULATION OF ADHERENS JUNCTION ORGANIZATION | 7 | 50 | 1.133e-05 | 0.0003424 |
| 155 | CELL PROJECTION ORGANIZATION | 32 | 902 | 1.198e-05 | 0.0003596 |
| 156 | CELL CYCLE PROCESS | 36 | 1081 | 1.325e-05 | 0.0003952 |
| 157 | POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION | 18 | 360 | 1.443e-05 | 0.0004277 |
| 158 | REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS | 14 | 229 | 1.453e-05 | 0.0004278 |
| 159 | NEURON PROJECTION DEVELOPMENT | 23 | 545 | 1.522e-05 | 0.0004455 |
| 160 | POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY | 7 | 53 | 1.681e-05 | 0.0004769 |
| 161 | POSITIVE REGULATION OF FIBROBLAST PROLIFERATION | 7 | 53 | 1.681e-05 | 0.0004769 |
| 162 | ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY | 9 | 95 | 1.681e-05 | 0.0004769 |
| 163 | NEURON DIFFERENTIATION | 31 | 874 | 1.659e-05 | 0.0004769 |
| 164 | CELLULAR RESPONSE TO ABIOTIC STIMULUS | 15 | 263 | 1.645e-05 | 0.0004769 |
| 165 | MORPHOGENESIS OF AN EPITHELIUM | 19 | 400 | 1.712e-05 | 0.0004798 |
| 166 | REGULATION OF ORGAN GROWTH | 8 | 73 | 1.707e-05 | 0.0004798 |
| 167 | RESPONSE TO ESTRADIOL | 11 | 146 | 1.777e-05 | 0.0004918 |
| 168 | DNA INTEGRITY CHECKPOINT | 11 | 146 | 1.777e-05 | 0.0004918 |
| 169 | POSITIVE REGULATION OF CHEMOTAXIS | 10 | 120 | 1.786e-05 | 0.0004918 |
| 170 | NEURON PROJECTION MORPHOGENESIS | 19 | 402 | 1.834e-05 | 0.000502 |
| 171 | REGULATION OF CELL MORPHOGENESIS | 23 | 552 | 1.863e-05 | 0.0005069 |
| 172 | REGULATION OF RESPONSE TO STRESS | 44 | 1468 | 1.909e-05 | 0.0005165 |
| 173 | CELL PART MORPHOGENESIS | 25 | 633 | 1.981e-05 | 0.0005328 |
| 174 | DIVALENT INORGANIC CATION TRANSPORT | 15 | 268 | 2.052e-05 | 0.0005487 |
| 175 | NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY | 9 | 98 | 2.162e-05 | 0.0005748 |
| 176 | MITOTIC DNA INTEGRITY CHECKPOINT | 9 | 100 | 2.544e-05 | 0.0006686 |
| 177 | REPLICATIVE SENESCENCE | 4 | 12 | 2.54e-05 | 0.0006686 |
| 178 | REGULATION OF CELLULAR COMPONENT BIOGENESIS | 28 | 767 | 2.603e-05 | 0.0006804 |
| 179 | RESPONSE TO UV | 10 | 126 | 2.732e-05 | 0.0007102 |
| 180 | REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY | 11 | 153 | 2.753e-05 | 0.0007116 |
| 181 | RESPONSE TO KETONE | 12 | 182 | 2.834e-05 | 0.0007284 |
| 182 | NEGATIVE REGULATION OF GENE EXPRESSION | 44 | 1493 | 2.87e-05 | 0.0007338 |
| 183 | POSITIVE REGULATION OF CELL PROLIFERATION | 29 | 814 | 2.902e-05 | 0.000738 |
| 184 | POSITIVE REGULATION OF PEPTIDASE ACTIVITY | 11 | 154 | 2.924e-05 | 0.0007395 |
| 185 | REGULATION OF HEMOPOIESIS | 16 | 314 | 3.441e-05 | 0.0008655 |
| 186 | HISTONE PHOSPHORYLATION | 5 | 25 | 3.568e-05 | 0.0008925 |
| 187 | POSITIVE REGULATION OF DNA DAMAGE RESPONSE SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 4 | 13 | 3.625e-05 | 0.0008971 |
| 188 | NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS | 24 | 616 | 3.617e-05 | 0.0008971 |
| 189 | REGULATION OF FIBROBLAST PROLIFERATION | 8 | 81 | 3.669e-05 | 0.0009005 |
| 190 | NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER | 27 | 740 | 3.677e-05 | 0.0009005 |
| 191 | CELL SUBSTRATE JUNCTION ASSEMBLY | 6 | 41 | 3.762e-05 | 0.0009166 |
| 192 | NEGATIVE REGULATION OF KINASE ACTIVITY | 14 | 250 | 3.843e-05 | 0.0009312 |
| 193 | RESPONSE TO OXIDATIVE STRESS | 17 | 352 | 3.864e-05 | 0.0009317 |
| 194 | NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS | 44 | 1517 | 4.193e-05 | 0.001006 |
| 195 | MEMBRANE DEPOLARIZATION | 7 | 61 | 4.279e-05 | 0.001008 |
| 196 | POSITIVE REGULATION OF VASCULATURE DEVELOPMENT | 10 | 133 | 4.351e-05 | 0.001008 |
| 197 | HEART DEVELOPMENT | 20 | 466 | 4.362e-05 | 0.001008 |
| 198 | REGULATION OF PROTEIN STABILITY | 13 | 221 | 4.378e-05 | 0.001008 |
| 199 | MESENCHYME DEVELOPMENT | 12 | 190 | 4.322e-05 | 0.001008 |
| 200 | CELLULAR RESPONSE TO ENDOGENOUS STIMULUS | 33 | 1008 | 4.347e-05 | 0.001008 |
| 201 | STEM CELL DIFFERENTIATION | 12 | 190 | 4.322e-05 | 0.001008 |
| 202 | REGULATION OF HEART GROWTH | 6 | 42 | 4.333e-05 | 0.001008 |
| 203 | REGENERATION | 11 | 161 | 4.404e-05 | 0.00101 |
| 204 | REGULATION OF BODY FLUID LEVELS | 21 | 506 | 4.57e-05 | 0.001042 |
| 205 | FOREBRAIN DEVELOPMENT | 17 | 357 | 4.608e-05 | 0.001046 |
| 206 | REGULATION OF SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 11 | 162 | 4.661e-05 | 0.001053 |
| 207 | TISSUE MIGRATION | 8 | 84 | 4.778e-05 | 0.001074 |
| 208 | REGULATION OF DEVELOPMENTAL GROWTH | 15 | 289 | 4.898e-05 | 0.001093 |
| 209 | RESPONSE TO EXTERNAL STIMULUS | 50 | 1821 | 4.912e-05 | 0.001093 |
| 210 | RESPONSE TO HYDROGEN PEROXIDE | 9 | 109 | 5.048e-05 | 0.001119 |
| 211 | CELLULAR RESPONSE TO HORMONE STIMULUS | 22 | 552 | 5.502e-05 | 0.001202 |
| 212 | TUBE DEVELOPMENT | 22 | 552 | 5.502e-05 | 0.001202 |
| 213 | REGULATION OF CELLULAR PROTEIN LOCALIZATION | 22 | 552 | 5.502e-05 | 0.001202 |
| 214 | COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION | 9 | 111 | 5.824e-05 | 0.001266 |
| 215 | REGULATION OF PHOSPHOLIPASE ACTIVITY | 7 | 64 | 5.856e-05 | 0.001267 |
| 216 | REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING | 10 | 138 | 5.956e-05 | 0.001283 |
| 217 | ZYMOGEN ACTIVATION | 9 | 112 | 6.248e-05 | 0.00134 |
| 218 | POSITIVE REGULATION OF CELL CYCLE | 16 | 332 | 6.682e-05 | 0.001426 |
| 219 | CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS | 4 | 15 | 6.752e-05 | 0.001429 |
| 220 | REGULATION OF CYTOPLASMIC TRANSPORT | 20 | 481 | 6.756e-05 | 0.001429 |
| 221 | AGING | 14 | 264 | 6.928e-05 | 0.001459 |
| 222 | NEGATIVE REGULATION OF MOLECULAR FUNCTION | 34 | 1079 | 7.043e-05 | 0.001476 |
| 223 | PROTEIN PHOSPHORYLATION | 31 | 944 | 7.083e-05 | 0.001478 |
| 224 | POSITIVE REGULATION OF INTRACELLULAR TRANSPORT | 17 | 370 | 7.163e-05 | 0.001481 |
| 225 | POSITIVE REGULATION OF LIPASE ACTIVITY | 7 | 66 | 7.15e-05 | 0.001481 |
| 226 | REGULATION OF LEUKOCYTE DIFFERENTIATION | 13 | 232 | 7.199e-05 | 0.001482 |
| 227 | REGULATION OF NEURON PROJECTION DEVELOPMENT | 18 | 408 | 7.414e-05 | 0.00152 |
| 228 | NEURON DEVELOPMENT | 25 | 687 | 7.494e-05 | 0.001529 |
| 229 | POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT | 5 | 29 | 7.579e-05 | 0.00154 |
| 230 | NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS | 34 | 1087 | 8.129e-05 | 0.001644 |
| 231 | POSITIVE REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS | 6 | 47 | 8.311e-05 | 0.001674 |
| 232 | CELL ACTIVATION | 22 | 568 | 8.352e-05 | 0.001675 |
| 233 | REGULATION OF CELLULAR LOCALIZATION | 38 | 1277 | 8.683e-05 | 0.001734 |
| 234 | NEGATIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION | 4 | 16 | 8.893e-05 | 0.001768 |
| 235 | RESPONSE TO X RAY | 5 | 30 | 8.98e-05 | 0.001778 |
| 236 | SENSORY ORGAN DEVELOPMENT | 20 | 493 | 9.449e-05 | 0.001863 |
| 237 | CENTRAL NERVOUS SYSTEM DEVELOPMENT | 29 | 872 | 9.829e-05 | 0.00193 |
| 238 | REGULATION OF SMOOTH MUSCLE CELL MIGRATION | 6 | 49 | 0.0001055 | 0.002058 |
| 239 | RESPONSE TO TOXIC SUBSTANCE | 13 | 241 | 0.0001057 | 0.002058 |
| 240 | CELL DIVISION | 19 | 460 | 0.0001119 | 0.002151 |
| 241 | EMBRYONIC MORPHOGENESIS | 21 | 539 | 0.0001116 | 0.002151 |
| 242 | HEMOSTASIS | 15 | 311 | 0.0001115 | 0.002151 |
| 243 | REGULATION OF INTRACELLULAR TRANSPORT | 23 | 621 | 0.0001125 | 0.002153 |
| 244 | IMMUNE SYSTEM PROCESS | 52 | 1984 | 0.000113 | 0.002154 |
| 245 | POSITIVE REGULATION OF SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 4 | 17 | 0.0001149 | 0.002182 |
| 246 | METAL ION TRANSPORT | 22 | 582 | 0.0001186 | 0.002243 |
| 247 | REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION | 14 | 278 | 0.0001199 | 0.002258 |
| 248 | NEGATIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 5 | 32 | 0.0001237 | 0.002295 |
| 249 | SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE | 8 | 96 | 0.0001238 | 0.002295 |
| 250 | HEAD DEVELOPMENT | 25 | 709 | 0.0001229 | 0.002295 |
| 251 | INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 5 | 32 | 0.0001237 | 0.002295 |
| 252 | NEGATIVE REGULATION OF TRANSFERASE ACTIVITY | 16 | 351 | 0.0001276 | 0.002357 |
| 253 | REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY | 12 | 213 | 0.0001292 | 0.002376 |
| 254 | CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND | 27 | 799 | 0.0001326 | 0.002429 |
| 255 | POSITIVE REGULATION OF CELL CYCLE PROCESS | 13 | 247 | 0.0001351 | 0.002465 |
| 256 | REGULATION OF MYELOID CELL DIFFERENTIATION | 11 | 183 | 0.0001393 | 0.002528 |
| 257 | REGULATION OF IMMUNE SYSTEM PROCESS | 40 | 1403 | 0.0001396 | 0.002528 |
| 258 | REGULATION OF PEPTIDASE ACTIVITY | 17 | 392 | 0.0001439 | 0.002595 |
| 259 | CELL CYCLE ARREST | 10 | 154 | 0.0001487 | 0.002672 |
| 260 | NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 9 | 126 | 0.0001551 | 0.002775 |
| 261 | GLAND DEVELOPMENT | 17 | 395 | 0.0001576 | 0.002809 |
| 262 | EPITHELIAL CELL DEVELOPMENT | 11 | 186 | 0.0001607 | 0.002832 |
| 263 | CELLULAR RESPONSE TO STEROID HORMONE STIMULUS | 12 | 218 | 0.0001605 | 0.002832 |
| 264 | REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS | 12 | 218 | 0.0001605 | 0.002832 |
| 265 | T CELL HOMEOSTASIS | 5 | 34 | 0.0001667 | 0.002927 |
| 266 | RESPONSE TO GROWTH FACTOR | 19 | 475 | 0.000169 | 0.002946 |
| 267 | TUBE MORPHOGENESIS | 15 | 323 | 0.0001688 | 0.002946 |
| 268 | BEHAVIOR | 20 | 516 | 0.0001738 | 0.003017 |
| 269 | REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT | 12 | 220 | 0.0001748 | 0.003023 |
| 270 | REGULATION OF PROTEIN LOCALIZATION | 30 | 950 | 0.0001843 | 0.003175 |
| 271 | POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS | 9 | 129 | 0.0001853 | 0.003182 |
| 272 | EYE DEVELOPMENT | 15 | 326 | 0.0001866 | 0.003191 |
| 273 | REGULATION OF APOPTOTIC SIGNALING PATHWAY | 16 | 363 | 0.0001872 | 0.003191 |
| 274 | CALCIUM ION TRANSPORT | 12 | 223 | 0.0001982 | 0.003365 |
| 275 | REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS | 6 | 55 | 0.0002023 | 0.00341 |
| 276 | POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION | 8 | 103 | 0.0002022 | 0.00341 |
| 277 | PROTEIN STABILIZATION | 9 | 131 | 0.0002081 | 0.003496 |
| 278 | POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS | 28 | 867 | 0.000211 | 0.003531 |
| 279 | POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS | 17 | 406 | 0.0002178 | 0.00363 |
| 280 | CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION | 16 | 368 | 0.0002185 | 0.00363 |
| 281 | T CELL SELECTION | 5 | 36 | 0.0002202 | 0.003646 |
| 282 | NEGATIVE REGULATION OF CELL JUNCTION ASSEMBLY | 4 | 20 | 0.0002254 | 0.003668 |
| 283 | NEGATIVE REGULATION OF CELL CYCLE ARREST | 4 | 20 | 0.0002254 | 0.003668 |
| 284 | POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT | 6 | 56 | 0.0002236 | 0.003668 |
| 285 | MELANOCYTE DIFFERENTIATION | 4 | 20 | 0.0002254 | 0.003668 |
| 286 | NEGATIVE REGULATION OF CELL DIFFERENTIATION | 22 | 609 | 0.0002246 | 0.003668 |
| 287 | REGULATION OF MUSCLE SYSTEM PROCESS | 11 | 195 | 0.0002425 | 0.003914 |
| 288 | TELENCEPHALON DEVELOPMENT | 12 | 228 | 0.0002431 | 0.003914 |
| 289 | CELLULAR RESPONSE TO MECHANICAL STIMULUS | 7 | 80 | 0.0002425 | 0.003914 |
| 290 | ENDOTHELIAL CELL MIGRATION | 6 | 57 | 0.0002467 | 0.003918 |
| 291 | MESENCHYMAL CELL DIFFERENTIATION | 9 | 134 | 0.0002467 | 0.003918 |
| 292 | RHYTHMIC PROCESS | 14 | 298 | 0.0002461 | 0.003918 |
| 293 | APOPTOTIC MITOCHONDRIAL CHANGES | 6 | 57 | 0.0002467 | 0.003918 |
| 294 | REGULATION OF PROTEIN AUTOPHOSPHORYLATION | 5 | 37 | 0.0002514 | 0.003978 |
| 295 | UROGENITAL SYSTEM DEVELOPMENT | 14 | 299 | 0.0002547 | 0.004017 |
| 296 | REGULATION OF EPITHELIAL CELL MIGRATION | 10 | 166 | 0.0002737 | 0.004302 |
| 297 | NEGATIVE REGULATION OF ORGAN GROWTH | 4 | 21 | 0.0002751 | 0.00431 |
| 298 | SKELETAL SYSTEM DEVELOPMENT | 18 | 455 | 0.0002857 | 0.004461 |
| 299 | MORPHOGENESIS OF A BRANCHING STRUCTURE | 10 | 167 | 0.0002872 | 0.004469 |
| 300 | CIRCADIAN RHYTHM | 9 | 137 | 0.0002909 | 0.004512 |
| 301 | REGULATION OF VASCULATURE DEVELOPMENT | 12 | 233 | 0.0002964 | 0.004582 |
| 302 | REGULATION OF CELL CYCLE G2 M PHASE TRANSITION | 6 | 59 | 0.0002985 | 0.004599 |
| 303 | CELLULAR RESPONSE TO LIPID | 18 | 457 | 0.0003011 | 0.004614 |
| 304 | NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY | 11 | 200 | 0.0003014 | 0.004614 |
| 305 | REGULATION OF LIPASE ACTIVITY | 7 | 83 | 0.0003047 | 0.004648 |
| 306 | REGULATION OF ION HOMEOSTASIS | 11 | 201 | 0.0003146 | 0.004783 |
| 307 | IMMUNE SYSTEM DEVELOPMENT | 21 | 582 | 0.0003162 | 0.004793 |
| 308 | SINGLE ORGANISM CELL ADHESION | 18 | 459 | 0.0003173 | 0.004794 |
| 309 | REGULATION OF PHOSPHOLIPASE C ACTIVITY | 5 | 39 | 0.0003237 | 0.004831 |
| 310 | MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL | 5 | 39 | 0.0003237 | 0.004831 |
| 311 | MITOTIC CELL CYCLE CHECKPOINT | 9 | 139 | 0.000324 | 0.004831 |
| 312 | REGULATION OF CELL SHAPE | 9 | 139 | 0.000324 | 0.004831 |
| 313 | RELEASE OF CYTOCHROME C FROM MITOCHONDRIA | 4 | 22 | 0.0003322 | 0.004938 |
| 314 | DEVELOPMENTAL PIGMENTATION | 5 | 40 | 0.0003653 | 0.005414 |
| 315 | PLATELET ACTIVATION | 9 | 142 | 0.0003792 | 0.005567 |
| 316 | PIGMENTATION | 7 | 86 | 0.000379 | 0.005567 |
| 317 | MEMBRANE ORGANIZATION | 28 | 899 | 0.0003781 | 0.005567 |
| 318 | POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING | 6 | 62 | 0.0003917 | 0.005732 |
| 319 | RESPONSE TO MAGNESIUM ION | 4 | 23 | 0.0003972 | 0.005788 |
| 320 | CELLULAR RESPONSE TO OXYGEN LEVELS | 9 | 143 | 0.0003993 | 0.005788 |
| 321 | ACTIN FILAMENT ORGANIZATION | 10 | 174 | 0.0003983 | 0.005788 |
| 322 | POSITIVE REGULATION OF ENDOCYTOSIS | 8 | 114 | 0.0004042 | 0.005841 |
| 323 | CELLULAR RESPONSE TO ESTROGEN STIMULUS | 5 | 41 | 0.0004109 | 0.005919 |
| 324 | NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION | 8 | 115 | 0.0004287 | 0.006119 |
| 325 | REGULATION OF CARTILAGE DEVELOPMENT | 6 | 63 | 0.0004274 | 0.006119 |
| 326 | NEUROEPITHELIAL CELL DIFFERENTIATION | 6 | 63 | 0.0004274 | 0.006119 |
| 327 | EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING | 20 | 554 | 0.0004351 | 0.006191 |
| 328 | ACTIVATION OF PROTEIN KINASE ACTIVITY | 13 | 279 | 0.0004402 | 0.006245 |
| 329 | RESPONSE TO IONIZING RADIATION | 9 | 145 | 0.0004421 | 0.006252 |
| 330 | DETECTION OF MECHANICAL STIMULUS | 5 | 42 | 0.0004605 | 0.006493 |
| 331 | BLOOD VESSEL ENDOTHELIAL CELL MIGRATION | 4 | 24 | 0.0004709 | 0.006619 |
| 332 | REGULATION OF CELL CYCLE PROCESS | 20 | 558 | 0.0004764 | 0.006658 |
| 333 | REGULATION OF OSSIFICATION | 10 | 178 | 0.0004765 | 0.006658 |
| 334 | POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT | 13 | 282 | 0.000487 | 0.00676 |
| 335 | ION TRANSMEMBRANE TRANSPORT | 26 | 822 | 0.0004864 | 0.00676 |
| 336 | REGULATION OF MAP KINASE ACTIVITY | 14 | 319 | 0.0004882 | 0.00676 |
| 337 | ENDOTHELIUM DEVELOPMENT | 7 | 90 | 5e-04 | 0.006904 |
| 338 | MULTI MULTICELLULAR ORGANISM PROCESS | 11 | 213 | 0.0005138 | 0.007052 |
| 339 | RESPONSE TO TRANSITION METAL NANOPARTICLE | 9 | 148 | 0.0005133 | 0.007052 |
| 340 | CELLULAR RESPONSE TO UV | 6 | 66 | 0.0005498 | 0.007505 |
| 341 | REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY | 4 | 25 | 0.0005538 | 0.007505 |
| 342 | NEGATIVE REGULATION OF SMOOTHENED SIGNALING PATHWAY | 4 | 25 | 0.0005538 | 0.007505 |
| 343 | NEGATIVE REGULATION OF CATALYTIC ACTIVITY | 26 | 829 | 0.0005518 | 0.007505 |
| 344 | ACTIVATION OF MAPKKK ACTIVITY | 3 | 11 | 0.0005549 | 0.007505 |
| 345 | POSITIVE REGULATION OF PROTEOLYSIS | 15 | 363 | 0.0005809 | 0.007835 |
| 346 | REGULATION OF CELL ACTIVATION | 18 | 484 | 0.0005929 | 0.007974 |
| 347 | CELL AGING | 6 | 67 | 0.0005961 | 0.007994 |
| 348 | POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT | 8 | 121 | 0.0006021 | 0.008051 |
| 349 | ACTIN FILAMENT BASED MOVEMENT | 7 | 93 | 0.0006096 | 0.008127 |
| 350 | THYMOCYTE AGGREGATION | 5 | 45 | 0.0006368 | 0.008418 |
| 351 | SPROUTING ANGIOGENESIS | 5 | 45 | 0.0006368 | 0.008418 |
| 352 | T CELL DIFFERENTIATION IN THYMUS | 5 | 45 | 0.0006368 | 0.008418 |
| 353 | NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT | 4 | 26 | 0.0006465 | 0.008522 |
| 354 | REGULATION OF HOMEOSTATIC PROCESS | 17 | 447 | 0.0006535 | 0.008589 |
| 355 | CELLULAR RESPONSE TO STRESS | 41 | 1565 | 0.0006553 | 0.008589 |
| 356 | AMEBOIDAL TYPE CELL MIGRATION | 9 | 154 | 0.0006839 | 0.008939 |
| 357 | REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND | 5 | 46 | 0.0007055 | 0.00917 |
| 358 | REGULATION OF CHONDROCYTE DIFFERENTIATION | 5 | 46 | 0.0007055 | 0.00917 |
| 359 | INOSITOL LIPID MEDIATED SIGNALING | 8 | 124 | 0.000708 | 0.009176 |
| 360 | NEGATIVE REGULATION OF CARDIAC MUSCLE TISSUE GROWTH | 3 | 12 | 0.0007314 | 0.009401 |
| 361 | NEGATIVE REGULATION OF HEART GROWTH | 3 | 12 | 0.0007314 | 0.009401 |
| 362 | POSITIVE REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS | 3 | 12 | 0.0007314 | 0.009401 |
| 363 | PHOSPHORYLATION | 34 | 1228 | 0.0007616 | 0.009763 |
| 364 | POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS | 13 | 296 | 0.0007648 | 0.009777 |
| 365 | RESPONSE TO ANTIBIOTIC | 5 | 47 | 0.0007796 | 0.009912 |
| 366 | POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS | 5 | 47 | 0.0007796 | 0.009912 |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | MOLECULAR FUNCTION REGULATOR | 51 | 1353 | 2.997e-09 | 2.784e-06 |
| 2 | ENZYME BINDING | 59 | 1737 | 6.952e-09 | 3.229e-06 |
| 3 | PROTEIN COMPLEX BINDING | 38 | 935 | 5.83e-08 | 1.805e-05 |
| 4 | CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE REGULATOR ACTIVITY | 7 | 28 | 1.799e-07 | 4.178e-05 |
| 5 | KINASE BINDING | 28 | 606 | 2.934e-07 | 5.452e-05 |
| 6 | MACROMOLECULAR COMPLEX BINDING | 47 | 1399 | 4.218e-07 | 6.531e-05 |
| 7 | CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 7 | 34 | 7.546e-07 | 0.0001001 |
| 8 | ENZYME REGULATOR ACTIVITY | 36 | 959 | 8.98e-07 | 0.0001043 |
| 9 | RECEPTOR BINDING | 47 | 1476 | 1.892e-06 | 0.0001953 |
| 10 | ENZYME ACTIVATOR ACTIVITY | 22 | 471 | 4.822e-06 | 0.0004479 |
| 11 | HISTONE KINASE ACTIVITY | 5 | 19 | 8.427e-06 | 0.0007117 |
| 12 | KINASE ACTIVITY | 30 | 842 | 2.099e-05 | 0.001625 |
| 13 | PROTEIN KINASE ACTIVITY | 25 | 640 | 2.378e-05 | 0.001699 |
| 14 | KINASE REGULATOR ACTIVITY | 12 | 186 | 3.51e-05 | 0.002174 |
| 15 | CELL ADHESION MOLECULE BINDING | 12 | 186 | 3.51e-05 | 0.002174 |
| 16 | INTEGRIN BINDING | 9 | 105 | 3.756e-05 | 0.002181 |
| 17 | ACTIN BINDING | 18 | 393 | 4.586e-05 | 0.002506 |
| 18 | RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING | 24 | 629 | 5.027e-05 | 0.002594 |
| 19 | TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING | 16 | 328 | 5.791e-05 | 0.002832 |
| 20 | TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING | 8 | 90 | 7.841e-05 | 0.003642 |
| 21 | PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY | 5 | 30 | 8.98e-05 | 0.003973 |
| 22 | ACTIN FILAMENT BINDING | 9 | 121 | 0.0001138 | 0.004805 |
| 23 | TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING | 15 | 315 | 0.0001284 | 0.005185 |
| 24 | CYCLIN BINDING | 4 | 19 | 0.0001826 | 0.007067 |
| 25 | TRANSCRIPTION FACTOR BINDING | 20 | 524 | 0.0002127 | 0.007902 |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | CELL JUNCTION | 51 | 1151 | 1.013e-11 | 5.918e-09 |
| 2 | CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX | 8 | 31 | 1.761e-08 | 5.144e-06 |
| 3 | MEMBRANE REGION | 43 | 1134 | 5.217e-08 | 1.016e-05 |
| 4 | PROTEIN KINASE COMPLEX | 10 | 90 | 1.325e-06 | 0.0001934 |
| 5 | CELL CELL JUNCTION | 20 | 383 | 2.506e-06 | 0.0002928 |
| 6 | ANCHORING JUNCTION | 22 | 489 | 8.719e-06 | 0.0008487 |
| 7 | MEMBRANE MICRODOMAIN | 16 | 288 | 1.195e-05 | 0.0009969 |
| 8 | CELL SUBSTRATE JUNCTION | 19 | 398 | 1.597e-05 | 0.001036 |
| 9 | CELL PROJECTION | 51 | 1786 | 1.438e-05 | 0.001036 |
| 10 | SYNAPSE | 28 | 754 | 1.917e-05 | 0.00112 |
| 11 | ACTIN CYTOSKELETON | 20 | 444 | 2.207e-05 | 0.001172 |
| 12 | PLASMA MEMBRANE REGION | 31 | 929 | 5.272e-05 | 0.002368 |
| 13 | PLASMA MEMBRANE PROTEIN COMPLEX | 21 | 510 | 5.116e-05 | 0.002368 |
| 14 | NEURON PART | 38 | 1265 | 7.131e-05 | 0.002975 |
| 15 | SOMATODENDRITIC COMPARTMENT | 24 | 650 | 8.366e-05 | 0.003257 |
| 16 | APICAL PART OF CELL | 16 | 361 | 0.0001759 | 0.006419 |
Over-represented Pathway
| Num | Pathway | Pathview | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|---|
| 1 | p53_signaling_pathway_hsa04115 | 45 | 68 | 7.969e-66 | 4.144e-64 | |
| 2 | Cellular_senescence_hsa04218 | 25 | 160 | 3.755e-18 | 9.763e-17 | |
| 3 | Cell_cycle_hsa04110 | 19 | 124 | 6.29e-14 | 1.09e-12 | |
| 4 | Focal_adhesion_hsa04510 | 20 | 199 | 4.144e-11 | 5.388e-10 | |
| 5 | PI3K_Akt_signaling_pathway_hsa04151 | 25 | 352 | 2.865e-10 | 2.979e-09 | |
| 6 | FoxO_signaling_pathway_hsa04068 | 15 | 132 | 2.155e-09 | 1.868e-08 | |
| 7 | Apoptosis_hsa04210 | 14 | 138 | 3.238e-08 | 2.405e-07 | |
| 8 | MAPK_signaling_pathway_hsa04010 | 17 | 295 | 3.922e-06 | 2.55e-05 | |
| 9 | Apoptosis_multiple_species_hsa04215 | 6 | 33 | 1.028e-05 | 5.942e-05 | |
| 10 | Ras_signaling_pathway_hsa04014 | 14 | 232 | 1.681e-05 | 8.742e-05 | |
| 11 | HIF_1_signaling_pathway_hsa04066 | 9 | 100 | 2.544e-05 | 0.0001202 | |
| 12 | Hippo_signaling_pathway_hsa04390 | 11 | 154 | 2.924e-05 | 0.0001267 | |
| 13 | ErbB_signaling_pathway_hsa04012 | 8 | 85 | 5.204e-05 | 0.0002082 | |
| 14 | Hedgehog_signaling_pathway_hsa04340 | 6 | 47 | 8.311e-05 | 0.0003087 | |
| 15 | Rap1_signaling_pathway_hsa04015 | 12 | 206 | 9.418e-05 | 0.0003265 | |
| 16 | Gap_junction_hsa04540 | 7 | 88 | 0.0004362 | 0.001418 | |
| 17 | Oocyte_meiosis_hsa04114 | 8 | 124 | 0.000708 | 0.002166 | |
| 18 | Hippo_signaling_pathway_multiple_species_hsa04392 | 4 | 29 | 0.0009903 | 0.002803 | |
| 19 | cGMP_PKG_signaling_pathway_hsa04022 | 9 | 163 | 0.001024 | 0.002803 | |
| 20 | Regulation_of_actin_cytoskeleton_hsa04810 | 10 | 208 | 0.001567 | 0.004074 | |
| 21 | Wnt_signaling_pathway_hsa04310 | 8 | 146 | 0.002024 | 0.005011 | |
| 22 | Sphingolipid_signaling_pathway_hsa04071 | 7 | 118 | 0.002446 | 0.005644 | |
| 23 | mTOR_signaling_pathway_hsa04150 | 8 | 151 | 0.002496 | 0.005644 | |
| 24 | Jak_STAT_signaling_pathway_hsa04630 | 8 | 162 | 0.003839 | 0.008318 | |
| 25 | Phosphatidylinositol_signaling_system_hsa04070 | 6 | 99 | 0.004436 | 0.009227 | |
| 26 | Tight_junction_hsa04530 | 8 | 170 | 0.005124 | 0.01025 | |
| 27 | TNF_signaling_pathway_hsa04668 | 6 | 108 | 0.006753 | 0.01301 | |
| 28 | ECM_receptor_interaction_hsa04512 | 5 | 82 | 0.008947 | 0.01662 | |
| 29 | cAMP_signaling_pathway_hsa04024 | 8 | 198 | 0.01231 | 0.02207 | |
| 30 | VEGF_signaling_pathway_hsa04370 | 4 | 59 | 0.01321 | 0.0229 | |
| 31 | Apelin_signaling_pathway_hsa04371 | 6 | 137 | 0.02007 | 0.03367 | |
| 32 | Phospholipase_D_signaling_pathway_hsa04072 | 6 | 146 | 0.02643 | 0.04295 | |
| 33 | AMPK_signaling_pathway_hsa04152 | 5 | 121 | 0.04031 | 0.06351 | |
| 34 | Autophagy_animal_hsa04140 | 5 | 128 | 0.04925 | 0.07533 | |
| 35 | Calcium_signaling_pathway_hsa04020 | 6 | 182 | 0.06457 | 0.09593 | |
| 36 | Adherens_junction_hsa04520 | 3 | 72 | 0.1011 | 0.146 | |
| 37 | Ferroptosis_hsa04216 | 2 | 40 | 0.1274 | 0.179 | |
| 38 | TGF_beta_signaling_pathway_hsa04350 | 3 | 84 | 0.1417 | 0.194 | |
| 39 | Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 | 4 | 139 | 0.1699 | 0.2265 | |
| 40 | NF_kappa_B_signaling_pathway_hsa04064 | 3 | 95 | 0.1829 | 0.2378 | |
| 41 | Cell_adhesion_molecules_.CAMs._hsa04514 | 4 | 145 | 0.1883 | 0.2388 | |
| 42 | Phagosome_hsa04145 | 4 | 152 | 0.2106 | 0.2607 | |
| 43 | Cytokine_cytokine_receptor_interaction_hsa04060 | 6 | 270 | 0.2424 | 0.2932 | |
| 44 | Mitophagy_animal_hsa04137 | 2 | 65 | 0.267 | 0.3156 | |
| 45 | Endocytosis_hsa04144 | 5 | 244 | 0.328 | 0.3791 | |
| 46 | Necroptosis_hsa04217 | 3 | 164 | 0.4685 | 0.5297 | |
| 47 | Lysosome_hsa04142 | 2 | 123 | 0.5709 | 0.6185 | |
| 48 | Neuroactive_ligand_receptor_interaction_hsa04080 | 2 | 278 | 0.9314 | 0.9884 |
lncRNA-mediated sponge
| Num | lncRNA | miRNAs | miRNAs count | Gene | Sponge regulatory network | lncRNA log2FC | lncRNA pvalue | Gene log2FC | Gene pvalue | lncRNA-gene Pearson correlation |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | RP11-389C8.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-429;hsa-miR-550a-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-93-5p | 24 | CCND2 | Sponge network | -2.039 | 0 | -1.641 | 0 | 0.52 |
| 2 | AF131215.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-550a-5p;hsa-miR-589-3p;hsa-miR-7-1-3p | 18 | CCND2 | Sponge network | -2.09 | 0 | -1.641 | 0 | 0.505 |
| 3 | LINC00702 |
hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-32-5p;hsa-miR-335-3p;hsa-miR-421;hsa-miR-500a-5p;hsa-miR-576-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 22 | THBS1 | Sponge network | -2.856 | 0 | -0.931 | 0.0014 | 0.501 |
| 4 | RP11-750H9.5 | hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-2355-3p;hsa-miR-301a-3p;hsa-miR-550a-5p;hsa-miR-877-5p | 10 | CCND2 | Sponge network | -1.959 | 0 | -1.641 | 0 | 0.493 |
| 5 | PCED1B-AS1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-301a-3p;hsa-miR-429;hsa-miR-877-5p;hsa-miR-93-5p;hsa-miR-96-5p | 18 | CCND2 | Sponge network | -0.672 | 0.02084 | -1.641 | 0 | 0.488 |
| 6 | DNM3OS |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-629-5p | 10 | IGF1 | Sponge network | 0.053 | 0.85755 | -0.879 | 0.00545 | 0.484 |
| 7 | SH3RF3-AS1 |
hsa-miR-16-1-3p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-29b-1-5p;hsa-miR-576-5p;hsa-miR-590-5p;hsa-miR-7-1-3p | 11 | THBS1 | Sponge network | -1.583 | 0 | -0.931 | 0.0014 | 0.469 |
| 8 | RP11-399O19.9 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-429;hsa-miR-7-1-3p;hsa-miR-93-5p | 18 | CCND2 | Sponge network | -0.873 | 0.00072 | -1.641 | 0 | 0.469 |
| 9 | MAGI2-AS3 |
hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-32-5p;hsa-miR-335-3p;hsa-miR-421;hsa-miR-576-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 20 | THBS1 | Sponge network | -1.892 | 0 | -0.931 | 0.0014 | 0.461 |
| 10 | AF131215.9 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-450b-5p;hsa-miR-503-5p;hsa-miR-589-3p;hsa-miR-590-3p | 14 | CCND2 | Sponge network | -1.808 | 0 | -1.641 | 0 | 0.46 |
| 11 | BZRAP1-AS1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-324-3p;hsa-miR-550a-5p;hsa-miR-877-5p;hsa-miR-93-5p | 17 | CCND2 | Sponge network | -0.785 | 0.00723 | -1.641 | 0 | 0.456 |
| 12 | LINC00996 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-320b;hsa-miR-550a-5p | 10 | CCND2 | Sponge network | -1.372 | 0.00025 | -1.641 | 0 | 0.454 |
| 13 | RP11-532F6.3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-590-3p | 17 | CCND2 | Sponge network | -2.028 | 0 | -1.641 | 0 | 0.445 |
| 14 | DNM3OS |
hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-7-1-3p | 12 | THBS1 | Sponge network | 0.053 | 0.85755 | -0.931 | 0.0014 | 0.435 |
| 15 | LINC00702 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-450b-5p;hsa-miR-501-5p;hsa-miR-503-5p;hsa-miR-550a-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-660-5p;hsa-miR-7-1-3p;hsa-miR-877-5p;hsa-miR-93-5p;hsa-miR-96-5p | 35 | CCND2 | Sponge network | -2.856 | 0 | -1.641 | 0 | 0.433 |
| 16 | LINC00426 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-2355-3p;hsa-miR-331-5p;hsa-miR-550a-5p;hsa-miR-877-5p;hsa-miR-96-5p | 10 | CCND2 | Sponge network | 0.629 | 0.03874 | -1.641 | 0 | 0.431 |
| 17 | TBX5-AS1 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-29b-3p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-421;hsa-miR-450b-5p;hsa-miR-576-5p;hsa-miR-629-5p | 15 | IGF1 | Sponge network | -2.108 | 0 | -0.879 | 0.00545 | 0.429 |
| 18 | RP11-456K23.1 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-29b-3p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-450b-5p;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-590-3p | 15 | IGF1 | Sponge network | -1.488 | 0 | -0.879 | 0.00545 | 0.429 |
| 19 | RP11-166D19.1 |
hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-32-5p;hsa-miR-335-3p;hsa-miR-421;hsa-miR-576-5p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-664a-3p;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 19 | THBS1 | Sponge network | -0.582 | 0.05253 | -0.931 | 0.0014 | 0.426 |
| 20 | LINC00702 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-29b-3p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-421;hsa-miR-450b-5p;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-629-5p | 17 | IGF1 | Sponge network | -2.856 | 0 | -0.879 | 0.00545 | 0.42 |
| 21 | AC109642.1 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-29b-3p;hsa-miR-301a-3p;hsa-miR-590-3p;hsa-miR-629-5p | 12 | IGF1 | Sponge network | -2.791 | 0 | -0.879 | 0.00545 | 0.41 |
| 22 | TBX5-AS1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-450b-5p;hsa-miR-501-5p;hsa-miR-503-5p;hsa-miR-550a-5p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-877-5p | 27 | CCND2 | Sponge network | -2.108 | 0 | -1.641 | 0 | 0.404 |
| 23 | CTD-2269F5.1 |
hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-32-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-7-1-3p | 15 | THBS1 | Sponge network | -1.576 | 0.00334 | -0.931 | 0.0014 | 0.404 |
| 24 | AC011899.9 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-503-5p;hsa-miR-550a-5p;hsa-miR-590-3p;hsa-miR-7-1-3p | 21 | CCND2 | Sponge network | -2.611 | 0 | -1.641 | 0 | 0.404 |
| 25 | RP11-253E3.3 | hsa-miR-101-3p;hsa-miR-141-3p;hsa-miR-146b-5p;hsa-miR-148a-3p;hsa-miR-15a-5p;hsa-miR-182-5p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-21-5p;hsa-miR-27b-5p;hsa-miR-29b-3p;hsa-miR-30b-5p;hsa-miR-30e-5p;hsa-miR-660-5p | 14 | CDK6 | Sponge network | -2.404 | 0 | -0.635 | 0.01747 | 0.403 |
| 26 | TBX5-AS1 |
hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-32-5p;hsa-miR-335-3p;hsa-miR-421;hsa-miR-576-5p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 17 | THBS1 | Sponge network | -2.108 | 0 | -0.931 | 0.0014 | 0.398 |
| 27 | LINC00968 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-450b-5p;hsa-miR-503-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-5p;hsa-miR-96-5p | 28 | CCND2 | Sponge network | -4.19 | 0 | -1.641 | 0 | 0.396 |
| 28 | RP11-720L2.4 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-93-5p | 12 | CCND2 | Sponge network | -2.305 | 0 | -1.641 | 0 | 0.394 |
| 29 | CTD-2013N24.2 |
hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-181b-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-335-3p;hsa-miR-500a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-7-1-3p | 16 | THBS1 | Sponge network | -1.745 | 0 | -0.931 | 0.0014 | 0.393 |
| 30 | MAGI2-AS3 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-29b-3p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-421;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-629-5p | 16 | IGF1 | Sponge network | -1.892 | 0 | -0.879 | 0.00545 | 0.384 |
| 31 | MAGI2-AS3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-429;hsa-miR-501-5p;hsa-miR-503-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-660-5p;hsa-miR-7-1-3p;hsa-miR-877-5p;hsa-miR-93-5p | 29 | CCND2 | Sponge network | -1.892 | 0 | -1.641 | 0 | 0.378 |
| 32 | AP001189.4 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-550a-5p | 10 | CCND2 | Sponge network | -3.07 | 0 | -1.641 | 0 | 0.377 |
| 33 | SH3RF3-AS1 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-26b-5p;hsa-miR-29b-3p;hsa-miR-576-5p | 11 | IGF1 | Sponge network | -1.583 | 0 | -0.879 | 0.00545 | 0.374 |
| 34 | RP11-1024P17.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-429;hsa-miR-589-3p;hsa-miR-590-3p | 22 | CCND2 | Sponge network | -2.062 | 0 | -1.641 | 0 | 0.374 |
| 35 | AC020571.3 |
hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-3065-5p;hsa-miR-335-3p | 10 | THBS1 | Sponge network | 0.248 | 0.40984 | -0.931 | 0.0014 | 0.367 |
| 36 | AC007743.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-142-5p;hsa-miR-17-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-29b-1-5p;hsa-miR-320b;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-550a-5p;hsa-miR-7-1-3p;hsa-miR-93-5p;hsa-miR-96-5p | 19 | SESN3 | Sponge network | -2.595 | 0 | -0.097 | 0.73838 | 0.366 |
| 37 | MIR497HG |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-450b-5p | 10 | IGF1 | Sponge network | -2.142 | 0 | -0.879 | 0.00545 | 0.361 |
| 38 | RP11-1008C21.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-550a-5p;hsa-miR-590-3p | 17 | CCND2 | Sponge network | -1.826 | 3.0E-5 | -1.641 | 0 | 0.36 |
| 39 | RP11-284N8.3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-93-5p;hsa-miR-96-5p | 24 | CCND2 | Sponge network | -0.761 | 0.05061 | -1.641 | 0 | 0.36 |
| 40 | RP11-367G6.3 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-877-5p | 11 | CCND2 | Sponge network | -0.777 | 0.06559 | -1.641 | 0 | 0.36 |
| 41 | RP4-555D20.2 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-21-3p;hsa-miR-28-5p;hsa-miR-550a-5p;hsa-miR-96-5p | 10 | CCND2 | Sponge network | -2.64 | 2.0E-5 | -1.641 | 0 | 0.359 |
| 42 | GAS6-AS2 |
hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-32-5p;hsa-miR-335-3p;hsa-miR-421;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 16 | THBS1 | Sponge network | -1.761 | 0 | -0.931 | 0.0014 | 0.355 |
| 43 | RP11-672A2.4 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-301a-3p | 12 | CCND2 | Sponge network | -2.68 | 0 | -1.641 | 0 | 0.355 |
| 44 | CTD-2013N24.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-429;hsa-miR-501-5p;hsa-miR-590-3p;hsa-miR-660-5p;hsa-miR-7-1-3p;hsa-miR-93-5p | 26 | CCND2 | Sponge network | -1.745 | 0 | -1.641 | 0 | 0.354 |
| 45 | AC011526.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-450b-5p;hsa-miR-503-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p | 12 | CCND2 | Sponge network | -2.783 | 0 | -1.641 | 0 | 0.352 |
| 46 | AC116366.6 | hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-324-3p;hsa-miR-550a-5p;hsa-miR-877-5p | 10 | CCND2 | Sponge network | -0.777 | 0.01756 | -1.641 | 0 | 0.351 |
| 47 | RP11-389C8.2 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-421;hsa-miR-590-3p;hsa-miR-629-5p | 12 | IGF1 | Sponge network | -2.039 | 0 | -0.879 | 0.00545 | 0.345 |
| 48 | CTD-2003C8.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-550a-5p;hsa-miR-590-3p;hsa-miR-93-5p | 14 | CCND2 | Sponge network | -3.403 | 0 | -1.641 | 0 | 0.345 |
| 49 | RP11-1223D19.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-142-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-25-3p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-590-3p;hsa-miR-93-5p | 16 | SESN3 | Sponge network | -0.862 | 0.05389 | -0.097 | 0.73838 | 0.34 |
| 50 | RP11-23P13.6 | hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-20a-5p;hsa-miR-28-5p;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-590-3p;hsa-miR-877-5p | 12 | CCND2 | Sponge network | -0.705 | 0.00072 | -1.641 | 0 | 0.34 |
| 51 | AC109642.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-503-5p;hsa-miR-550a-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p | 27 | CCND2 | Sponge network | -2.791 | 0 | -1.641 | 0 | 0.339 |
| 52 | RP11-401P9.4 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-331-5p;hsa-miR-550a-5p;hsa-miR-590-5p;hsa-miR-93-5p | 22 | CCND2 | Sponge network | -3.04 | 0 | -1.641 | 0 | 0.337 |
| 53 | GAS6-AS2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-429;hsa-miR-550a-5p;hsa-miR-590-5p;hsa-miR-7-1-3p | 25 | CCND2 | Sponge network | -1.761 | 0 | -1.641 | 0 | 0.337 |
| 54 | RP11-354E11.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-590-3p;hsa-miR-96-5p | 19 | CCND2 | Sponge network | -2.138 | 0 | -1.641 | 0 | 0.335 |
| 55 | RP11-479G22.8 | hsa-miR-101-3p;hsa-miR-146b-5p;hsa-miR-148a-3p;hsa-miR-16-1-3p;hsa-miR-182-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-23b-3p;hsa-miR-27b-3p;hsa-miR-27b-5p;hsa-miR-30d-3p;hsa-miR-429;hsa-miR-664a-3p | 13 | CDK6 | Sponge network | -0.38 | 0.08909 | -0.635 | 0.01747 | 0.335 |
| 56 | MIR497HG |
hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-671-5p;hsa-miR-7-1-3p | 14 | THBS1 | Sponge network | -2.142 | 0 | -0.931 | 0.0014 | 0.33 |
| 57 | AC109642.1 |
hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-32-5p;hsa-miR-590-3p;hsa-miR-92a-3p | 13 | THBS1 | Sponge network | -2.791 | 0 | -0.931 | 0.0014 | 0.328 |
| 58 | LINC00472 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-301a-3p;hsa-miR-450b-5p;hsa-miR-503-5p;hsa-miR-550a-5p;hsa-miR-7-1-3p;hsa-miR-93-5p | 21 | CCND2 | Sponge network | -2.952 | 0 | -1.641 | 0 | 0.327 |
| 59 | AC144831.1 |
hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-550a-5p;hsa-miR-7-1-3p;hsa-miR-877-5p;hsa-miR-93-5p | 16 | CCND2 | Sponge network | -2.063 | 0 | -1.641 | 0 | 0.327 |
| 60 | RP11-1024P17.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148b-3p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-193a-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-301a-3p | 15 | PTEN | Sponge network | -2.062 | 0 | -0.419 | 0.00014 | 0.325 |
| 61 | CTD-2013N24.2 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-181b-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-29b-3p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-590-3p | 15 | IGF1 | Sponge network | -1.745 | 0 | -0.879 | 0.00545 | 0.323 |
| 62 | RP11-166D19.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-429;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-877-5p;hsa-miR-96-5p | 25 | CCND2 | Sponge network | -0.582 | 0.05253 | -1.641 | 0 | 0.322 |
| 63 | LINC00092 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-503-5p;hsa-miR-589-3p;hsa-miR-590-3p | 15 | CCND2 | Sponge network | -2.383 | 0 | -1.641 | 0 | 0.321 |
| 64 | RP11-166D19.1 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-421;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-629-5p | 12 | IGF1 | Sponge network | -0.582 | 0.05253 | -0.879 | 0.00545 | 0.319 |
| 65 | RP11-359E10.1 | hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-7-1-3p | 10 | THBS1 | Sponge network | -0.504 | 0.29085 | -0.931 | 0.0014 | 0.319 |
| 66 | RP11-293M10.6 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-301a-3p;hsa-miR-576-5p;hsa-miR-93-5p | 11 | SESN3 | Sponge network | -1.199 | 0.00063 | -0.097 | 0.73838 | 0.317 |
| 67 | NR2F1-AS1 |
hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-32-5p;hsa-miR-335-3p;hsa-miR-421;hsa-miR-590-3p;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 13 | THBS1 | Sponge network | -0.427 | 0.1559 | -0.931 | 0.0014 | 0.317 |
| 68 | BAIAP2-AS1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-142-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-25-3p;hsa-miR-320b;hsa-miR-550a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-93-5p | 16 | SESN3 | Sponge network | -0.182 | 0.51705 | -0.097 | 0.73838 | 0.317 |
| 69 | RP11-1094H24.4 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-193a-3p;hsa-miR-20b-5p;hsa-miR-769-3p;hsa-miR-92a-3p;hsa-miR-93-5p;hsa-miR-942-5p | 10 | CCND1 | Sponge network | -0.831 | 0.01225 | -0.296 | 0.2554 | 0.317 |
| 70 | RP5-1042I8.7 |
hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-20a-5p;hsa-miR-320b;hsa-miR-331-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p | 14 | CCND2 | Sponge network | -0.733 | 0.00018 | -1.641 | 0 | 0.316 |
| 71 | AC079630.4 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-331-5p;hsa-miR-550a-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-877-5p;hsa-miR-93-5p | 20 | CCND2 | Sponge network | -3.758 | 0 | -1.641 | 0 | 0.314 |
| 72 | RP4-668J24.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-2355-3p | 10 | CCND2 | Sponge network | -2.397 | 0.00331 | -1.641 | 0 | 0.314 |
| 73 | RP11-462G12.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-25-3p;hsa-miR-29b-1-5p;hsa-miR-363-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-93-5p | 18 | SESN3 | Sponge network | -1.071 | 0.01175 | -0.097 | 0.73838 | 0.313 |
| 74 | RP11-354E11.2 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-629-5p | 12 | IGF1 | Sponge network | -2.138 | 0 | -0.879 | 0.00545 | 0.313 |
| 75 | LINC00702 |
hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148b-3p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-425-5p;hsa-miR-454-3p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p;hsa-miR-93-5p | 21 | PTEN | Sponge network | -2.856 | 0 | -0.419 | 0.00014 | 0.312 |
| 76 | DIO3OS |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-550a-5p;hsa-miR-589-3p;hsa-miR-877-5p | 19 | CCND2 | Sponge network | -1.936 | 0.00085 | -1.641 | 0 | 0.307 |
| 77 | RP11-283G6.4 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-301a-3p;hsa-miR-450b-5p;hsa-miR-93-5p;hsa-miR-96-5p | 16 | CCND2 | Sponge network | -3.669 | 1.0E-5 | -1.641 | 0 | 0.305 |
| 78 | MAGI2-AS3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-425-5p;hsa-miR-429;hsa-miR-454-3p;hsa-miR-501-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-660-5p;hsa-miR-671-5p;hsa-miR-93-5p | 24 | ZMAT3 | Sponge network | -1.892 | 0 | -0.319 | 0.07814 | 0.305 |
| 79 | CTC-366B18.4 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-320b;hsa-miR-590-3p;hsa-miR-93-5p | 11 | CCND2 | Sponge network | -0.652 | 0.01265 | -1.641 | 0 | 0.303 |
| 80 | RP11-389C8.2 |
hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148b-3p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-193a-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-301a-3p;hsa-miR-7-1-3p;hsa-miR-93-5p | 17 | PTEN | Sponge network | -2.039 | 0 | -0.419 | 0.00014 | 0.303 |
| 81 | SAP30L-AS1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-26b-3p;hsa-miR-421;hsa-miR-92a-3p;hsa-miR-93-5p | 13 | SESN3 | Sponge network | 0.631 | 0.02291 | -0.097 | 0.73838 | 0.303 |
| 82 | FENDRR |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-331-5p;hsa-miR-450b-5p;hsa-miR-503-5p;hsa-miR-550a-5p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-93-5p;hsa-miR-96-5p | 27 | CCND2 | Sponge network | -4.222 | 0 | -1.641 | 0 | 0.301 |
| 83 | RP11-378A13.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-503-5p;hsa-miR-550a-5p;hsa-miR-590-3p;hsa-miR-877-5p;hsa-miR-93-5p | 21 | CCND2 | Sponge network | -1.713 | 0 | -1.641 | 0 | 0.301 |
| 84 | RP11-760H22.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-142-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-25-3p;hsa-miR-26b-3p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-454-3p | 17 | SESN3 | Sponge network | 0.688 | 0.02737 | -0.097 | 0.73838 | 0.301 |
| 85 | BAIAP2-AS1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-193a-3p;hsa-miR-193b-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-365a-3p;hsa-miR-590-3p;hsa-miR-769-3p;hsa-miR-93-5p;hsa-miR-942-5p | 15 | CCND1 | Sponge network | -0.182 | 0.51705 | -0.296 | 0.2554 | 0.3 |
| 86 | GAS6-AS2 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-421 | 10 | IGF1 | Sponge network | -1.761 | 0 | -0.879 | 0.00545 | 0.3 |
| 87 | AC011899.9 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-26b-5p;hsa-miR-301a-3p;hsa-miR-590-3p | 10 | IGF1 | Sponge network | -2.611 | 0 | -0.879 | 0.00545 | 0.3 |
| 88 | LINC00922 |
hsa-miR-17-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-20a-5p;hsa-miR-32-5p;hsa-miR-421;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 11 | THBS1 | Sponge network | -0.842 | 0.11239 | -0.931 | 0.0014 | 0.3 |
| 89 | RP4-647J21.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-200a-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-550a-5p;hsa-miR-7-1-3p;hsa-miR-93-5p | 14 | CCND2 | Sponge network | -0.153 | 0.73575 | -1.641 | 0 | 0.299 |
| 90 | RP11-815I9.4 | hsa-miR-148b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-29b-1-5p;hsa-miR-590-5p;hsa-miR-671-5p | 11 | ZMAT3 | Sponge network | -0.881 | 0.0002 | -0.319 | 0.07814 | 0.299 |
| 91 | LINC00922 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-501-5p;hsa-miR-7-1-3p;hsa-miR-877-5p | 18 | CCND2 | Sponge network | -0.842 | 0.11239 | -1.641 | 0 | 0.298 |
| 92 | RP11-476D10.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-550a-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-96-5p | 22 | CCND2 | Sponge network | -4.519 | 0 | -1.641 | 0 | 0.296 |
| 93 | MAGI2-AS3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-25-3p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-32-5p;hsa-miR-320b;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-92a-3p;hsa-miR-93-5p | 26 | SESN3 | Sponge network | -1.892 | 0 | -0.097 | 0.73838 | 0.295 |
| 94 | RP11-24F11.2 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-320b;hsa-miR-877-5p | 10 | CCND2 | Sponge network | -0.836 | 0.01357 | -1.641 | 0 | 0.295 |
| 95 | RP11-166D19.1 |
hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-425-5p;hsa-miR-454-3p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 19 | PTEN | Sponge network | -0.582 | 0.05253 | -0.419 | 0.00014 | 0.295 |
| 96 | RP11-5C23.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-590-3p | 11 | CCND2 | Sponge network | -0.758 | 0.00105 | -1.641 | 0 | 0.295 |
| 97 | RP11-416I2.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-193a-3p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-590-3p;hsa-miR-769-3p;hsa-miR-92a-3p;hsa-miR-93-5p;hsa-miR-942-5p | 16 | CCND1 | Sponge network | 3.177 | 1.0E-5 | -0.296 | 0.2554 | 0.294 |
| 98 | CTC-523E23.4 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-362-3p;hsa-miR-362-5p;hsa-miR-454-3p;hsa-miR-590-3p;hsa-miR-671-5p | 17 | ZMAT3 | Sponge network | -1.636 | 0.00051 | -0.319 | 0.07814 | 0.294 |
| 99 | RP11-456K23.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-450b-5p;hsa-miR-501-5p;hsa-miR-503-5p;hsa-miR-550a-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-5p | 26 | CCND2 | Sponge network | -1.488 | 0 | -1.641 | 0 | 0.292 |
| 100 | WDFY3-AS2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-18a-5p;hsa-miR-193a-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-425-5p;hsa-miR-590-5p;hsa-miR-7-1-3p | 16 | PTEN | Sponge network | -1.297 | 0 | -0.419 | 0.00014 | 0.292 |
| 101 | LINC00961 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-589-3p;hsa-miR-96-5p | 18 | CCND2 | Sponge network | -2.724 | 0 | -1.641 | 0 | 0.292 |
| 102 | RP11-284N8.3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-26b-3p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-33a-5p;hsa-miR-576-5p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-93-5p;hsa-miR-96-5p | 18 | SESN3 | Sponge network | -0.761 | 0.05061 | -0.097 | 0.73838 | 0.291 |
| 103 | RP11-1008C21.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-26b-3p;hsa-miR-301a-3p;hsa-miR-32-5p;hsa-miR-320b;hsa-miR-92a-3p;hsa-miR-93-5p | 16 | SESN3 | Sponge network | -1.249 | 0 | -0.097 | 0.73838 | 0.291 |
| 104 | RP11-400K9.4 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-7-1-3p;hsa-miR-93-5p | 17 | CCND2 | Sponge network | -1.193 | 0.00359 | -1.641 | 0 | 0.29 |
| 105 | RP3-395M20.8 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-324-3p;hsa-miR-550a-5p;hsa-miR-590-3p | 10 | CCND2 | Sponge network | -0.076 | 0.8237 | -1.641 | 0 | 0.29 |
| 106 | AC004947.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-877-5p;hsa-miR-93-5p | 23 | CCND2 | Sponge network | -3.94 | 0 | -1.641 | 0 | 0.289 |
| 107 | AC006129.1 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-877-5p | 11 | CCND2 | Sponge network | -1.587 | 0.00086 | -1.641 | 0 | 0.287 |
| 108 | LINC00968 |
hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-421;hsa-miR-450b-5p;hsa-miR-590-3p | 12 | IGF1 | Sponge network | -4.19 | 0 | -0.879 | 0.00545 | 0.287 |
| 109 | RP11-774O3.3 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-21-3p;hsa-miR-28-5p;hsa-miR-590-3p;hsa-miR-7-1-3p | 10 | CCND2 | Sponge network | -0.694 | 0.00725 | -1.641 | 0 | 0.287 |
| 110 | SH3RF3-AS1 |
hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-503-5p;hsa-miR-590-5p;hsa-miR-7-1-3p | 16 | CCND2 | Sponge network | -1.583 | 0 | -1.641 | 0 | 0.286 |
| 111 | TBX5-AS1 |
hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148b-3p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-193a-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 19 | PTEN | Sponge network | -2.108 | 0 | -0.419 | 0.00014 | 0.286 |
| 112 | RP11-244O19.1 |
hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-26b-3p;hsa-miR-363-3p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-5p | 11 | SESN3 | Sponge network | -0.428 | 0.21699 | -0.097 | 0.73838 | 0.285 |
| 113 | TBX5-AS1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-25-3p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-32-5p;hsa-miR-33a-5p;hsa-miR-363-3p;hsa-miR-421;hsa-miR-550a-5p;hsa-miR-576-5p;hsa-miR-7-1-3p;hsa-miR-92a-3p | 24 | SESN3 | Sponge network | -2.108 | 0 | -0.097 | 0.73838 | 0.283 |
| 114 | AGAP11 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-590-5p;hsa-miR-93-5p | 12 | CCND2 | Sponge network | -2.127 | 0 | -1.641 | 0 | 0.283 |
| 115 | LINC00968 |
hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-421;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-671-5p | 15 | THBS1 | Sponge network | -4.19 | 0 | -0.931 | 0.0014 | 0.283 |
| 116 | CTC-429P9.1 | hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-17-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-29a-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-33a-5p;hsa-miR-93-5p | 11 | SESN3 | Sponge network | -0.908 | 0.00061 | -0.097 | 0.73838 | 0.279 |
| 117 | CTD-2003C8.2 |
hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-590-3p;hsa-miR-671-5p | 10 | THBS1 | Sponge network | -3.403 | 0 | -0.931 | 0.0014 | 0.279 |
| 118 | AC020571.3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-877-5p;hsa-miR-96-5p | 11 | CCND2 | Sponge network | 0.248 | 0.40984 | -1.641 | 0 | 0.274 |
| 119 | NR2F1-AS1 |
hsa-miR-15b-3p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-29b-3p;hsa-miR-362-5p;hsa-miR-421;hsa-miR-590-3p;hsa-miR-629-5p | 11 | IGF1 | Sponge network | -0.427 | 0.1559 | -0.879 | 0.00545 | 0.273 |
| 120 | LINC00883 |
hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-425-5p;hsa-miR-501-5p;hsa-miR-590-3p;hsa-miR-664a-3p | 10 | ZMAT3 | Sponge network | -1.466 | 0 | -0.319 | 0.07814 | 0.272 |
| 121 | AC010226.4 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-93-5p | 10 | CCND2 | Sponge network | -1.081 | 2.0E-5 | -1.641 | 0 | 0.272 |
| 122 | MIR497HG |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-450b-5p;hsa-miR-501-5p;hsa-miR-503-5p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-877-5p;hsa-miR-93-5p;hsa-miR-96-5p | 30 | CCND2 | Sponge network | -2.142 | 0 | -1.641 | 0 | 0.271 |
| 123 | DNM3OS |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-320b;hsa-miR-331-5p;hsa-miR-501-5p;hsa-miR-550a-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-7-1-3p;hsa-miR-93-5p | 22 | CCND2 | Sponge network | 0.053 | 0.85755 | -1.641 | 0 | 0.27 |
| 124 | RP4-575N6.4 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-301a-3p | 11 | CCND2 | Sponge network | -3.22 | 0 | -1.641 | 0 | 0.27 |
| 125 | C1orf132 |
hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-28-5p;hsa-miR-320b;hsa-miR-450b-5p;hsa-miR-503-5p;hsa-miR-550a-5p;hsa-miR-590-3p;hsa-miR-877-5p;hsa-miR-93-5p | 17 | CCND2 | Sponge network | -0.86 | 0.02429 | -1.641 | 0 | 0.269 |
| 126 | MAGI2-AS3 |
hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148b-3p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-425-5p;hsa-miR-454-3p;hsa-miR-7-1-3p;hsa-miR-92a-3p;hsa-miR-93-5p | 20 | PTEN | Sponge network | -1.892 | 0 | -0.419 | 0.00014 | 0.268 |
| 127 | RP11-462G12.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-142-5p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-26b-3p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-92a-3p;hsa-miR-93-5p | 16 | SESN3 | Sponge network | -0.602 | 0.22954 | -0.097 | 0.73838 | 0.268 |
| 128 | RP11-244O19.1 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-20a-5p;hsa-miR-324-3p;hsa-miR-590-3p;hsa-miR-877-5p;hsa-miR-93-5p | 10 | CCND2 | Sponge network | -0.428 | 0.21699 | -1.641 | 0 | 0.267 |
| 129 | RP11-389C8.2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-421;hsa-miR-550a-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-93-5p | 19 | SESN3 | Sponge network | -2.039 | 0 | -0.097 | 0.73838 | 0.265 |
| 130 | RP11-399O19.9 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-7-1-3p;hsa-miR-93-5p | 13 | PTEN | Sponge network | -0.873 | 0.00072 | -0.419 | 0.00014 | 0.264 |
| 131 | RP11-20J15.3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-320b;hsa-miR-550a-5p;hsa-miR-877-5p | 15 | CCND2 | Sponge network | -1.709 | 0.0268 | -1.641 | 0 | 0.264 |
| 132 | AC022182.3 |
hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-877-5p;hsa-miR-93-5p | 11 | CCND2 | Sponge network | -0.559 | 0.20451 | -1.641 | 0 | 0.263 |
| 133 | RP11-536K7.3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-2355-3p;hsa-miR-324-3p;hsa-miR-877-5p;hsa-miR-93-5p | 19 | CCND2 | Sponge network | -1.239 | 5.0E-5 | -1.641 | 0 | 0.263 |
| 134 | RP11-517P14.2 |
hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-590-3p;hsa-miR-93-5p | 13 | ZMAT3 | Sponge network | -0.795 | 6.0E-5 | -0.319 | 0.07814 | 0.261 |
| 135 | AC109642.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-25-3p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-32-5p;hsa-miR-320b;hsa-miR-363-3p;hsa-miR-550a-5p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-5p;hsa-miR-96-5p | 24 | SESN3 | Sponge network | -2.791 | 0 | -0.097 | 0.73838 | 0.261 |
| 136 | RP11-67L2.2 |
hsa-miR-106b-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-550a-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p | 11 | CCND2 | Sponge network | -1.062 | 0 | -1.641 | 0 | 0.259 |
| 137 | CTD-2376I4.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-7-1-3p | 10 | SESN3 | Sponge network | 0 | 0.99994 | -0.097 | 0.73838 | 0.258 |
| 138 | RP11-456K23.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-142-5p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-25-3p;hsa-miR-29a-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-454-3p;hsa-miR-550a-5p;hsa-miR-576-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-5p | 23 | SESN3 | Sponge network | -1.488 | 0 | -0.097 | 0.73838 | 0.256 |
| 139 | AC003991.3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-193a-3p;hsa-miR-193b-3p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-365a-3p;hsa-miR-425-5p;hsa-miR-590-3p;hsa-miR-7-1-3p;hsa-miR-769-3p;hsa-miR-92a-3p;hsa-miR-93-5p | 20 | CCND1 | Sponge network | -0.787 | 0.08132 | -0.296 | 0.2554 | 0.255 |
| 140 | LIPE-AS1 |
hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-193a-3p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-301a-3p;hsa-miR-425-5p;hsa-miR-590-5p;hsa-miR-93-5p | 14 | PTEN | Sponge network | -0.734 | 0.00039 | -0.419 | 0.00014 | 0.254 |
| 141 | RP11-53M11.3 | hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-3p;hsa-miR-301a-3p;hsa-miR-7-1-3p | 10 | CCND2 | Sponge network | -2.058 | 0.01204 | -1.641 | 0 | 0.253 |
| 142 | AC008268.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-142-5p;hsa-miR-17-5p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-29a-5p;hsa-miR-29b-1-5p;hsa-miR-550a-5p;hsa-miR-93-5p | 13 | SESN3 | Sponge network | -5.661 | 0 | -0.097 | 0.73838 | 0.253 |