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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7a-5p AIFM1 -1.37 0 0.7 0 TargetScan; miRNATAP -0.11 0.00018 NA
2 hsa-let-7b-5p AIFM1 -1.62 0 0.7 0 miRNATAP -0.12 0 NA
3 hsa-miR-125a-5p AIFM1 -1.05 0 0.7 0 miRanda -0.08 0.00249 NA
4 hsa-miR-125b-5p AIFM1 -0.55 0.01072 0.7 0 miRNATAP -0.09 0.00028 NA
5 hsa-miR-145-5p AIFM1 -1.35 0 0.7 0 miRNATAP -0.09 1.0E-5 20332243 Artificial overexpression of miR145 by using adenoviral vectors in prostate cancer PC-3 and DU145 cells significantly downregulated BNIP3 together with the upregulation of AIF reduced cell growth and increased cell death
6 hsa-miR-155-5p AIFM1 0.81 0.00061 0.7 0 miRNAWalker2 validate -0.06 0.01116 NA
7 hsa-miR-199a-5p AIFM1 1.31 0 0.7 0 miRanda -0.06 0.00903 NA
8 hsa-miR-143-3p AKT1 -1.21 1.0E-5 -0.13 0.25348 miRNAWalker2 validate -0.06 0.00284 NA
9 hsa-let-7a-5p AKT2 -1.37 0 0.16 0.1135 TargetScan -0.12 0 NA
10 hsa-miR-29a-3p AKT2 0.1 0.5732 0.16 0.1135 MirTarget -0.1 4.0E-5 24076586 Furthermore a feed-back loop comprising of c-Myc miR-29 family and Akt2 were found in myeloid leukemogenesis
11 hsa-miR-29c-3p AKT2 1.32 0 0.16 0.1135 MirTarget -0.07 5.0E-5 NA
12 hsa-miR-30d-3p AKT2 0 0.98646 0.16 0.1135 mirMAP -0.05 0.01424 NA
13 hsa-miR-30e-3p AKT2 -0.1 0.52624 0.16 0.1135 mirMAP -0.07 0.01256 NA
14 hsa-miR-106a-5p AKT3 1.39 6.0E-5 -1.44 0 miRNATAP -0.09 0.01547 NA
15 hsa-miR-106b-5p AKT3 1.47 0 -1.44 0 miRNATAP -0.16 0.00426 NA
16 hsa-miR-107 AKT3 0.66 0 -1.44 0 PITA; miRanda -0.26 0.0031 NA
17 hsa-miR-142-3p AKT3 3.98 0 -1.44 0 miRanda -0.1 0.0026 NA
18 hsa-miR-146b-5p AKT3 1.09 1.0E-5 -1.44 0 miRNAWalker2 validate -0.15 0.00189 NA
19 hsa-miR-15a-5p AKT3 1.63 0 -1.44 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.41 0 NA
20 hsa-miR-16-5p AKT3 0.75 0 -1.44 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.27 0.0001 NA
21 hsa-miR-17-3p AKT3 1.37 0 -1.44 0 miRNATAP -0.15 0.01027 NA
22 hsa-miR-17-5p AKT3 2.07 0 -1.44 0 TargetScan; miRNATAP -0.22 0 NA
23 hsa-miR-181a-5p AKT3 -0.38 0.05621 -1.44 0 miRNATAP -0.23 9.0E-5 NA
24 hsa-miR-181b-5p AKT3 0.67 0.00024 -1.44 0 miRNATAP -0.37 0 NA
25 hsa-miR-20a-5p AKT3 2.65 0 -1.44 0 miRNATAP -0.24 0 NA
26 hsa-miR-22-3p AKT3 1.43 0 -1.44 0 miRNATAP -0.26 0.00109 NA
27 hsa-miR-28-3p AKT3 0.39 0.00778 -1.44 0 miRNATAP -0.2 0.01226 NA
28 hsa-miR-29a-3p AKT3 0.1 0.5732 -1.44 0 miRNATAP -0.15 0.02016 NA
29 hsa-miR-29b-2-5p AKT3 0.35 0.19484 -1.44 0 mirMAP -0.18 2.0E-5 NA
30 hsa-miR-29b-3p AKT3 3.11 0 -1.44 0 miRNATAP -0.27 0 26512921 MicroRNA 29B mir 29b regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3
31 hsa-miR-3065-5p AKT3 0.65 0.09995 -1.44 0 mirMAP -0.18 0 NA
32 hsa-miR-335-3p AKT3 1.51 0 -1.44 0 mirMAP -0.13 0.01067 NA
33 hsa-miR-362-5p AKT3 0.66 0.02433 -1.44 0 PITA; TargetScan; miRNATAP -0.23 0 NA
34 hsa-miR-424-5p AKT3 1.26 1.0E-5 -1.44 0 miRNATAP -0.09 0.02225 26315541 Silencing Akt3 and E2F3 by siRNA pheno-copied the effect of ectopic miR-424 on HCC growth; Whereas overexpression of Akt3 and E2F3 attenuated the effect of miR-424 on HCC growth
35 hsa-miR-542-3p AKT3 1.62 0 -1.44 0 miRanda -0.19 1.0E-5 NA
36 hsa-miR-93-5p AKT3 1.51 0 -1.44 0 miRNATAP -0.25 0 NA
37 hsa-miR-195-3p APAF1 -1.33 0 0.05 0.6283 mirMAP -0.06 0.00936 NA
38 hsa-miR-23a-3p APAF1 0.11 0.39309 0.05 0.6283 miRNATAP -0.13 0.00069 24992592; 24249161 Luciferase assay was performed to verify a putative target site of miR-23a in the 3'-UTR of apoptosis protease activating factor 1 APAF1 mRNA; The expression levels of miR-23a and APAF1 in CRC cell lines SW480 and SW620 and clinical samples were assessed using reverse transcription-quantitative real-time PCR RT-qPCR and Western blot; Moreover miR-23a up-regulation was coupled with APAF1 down-regulation in CRC tissue samples;We found that the expression of miR-23a was increased and the level of apoptosis-activating factor-1 APAF-1 was decreased in 5-FU-treated colon cancer cells compared to untreated cells; APAF-1 as a target gene of miR-23a was identified and miR-23a antisense-induced increase in the activation of caspase-9 was observed
39 hsa-miR-23b-3p APAF1 -0.07 0.62059 0.05 0.6283 miRNATAP -0.11 0.00216 NA
40 hsa-miR-27a-3p APAF1 0.43 0.00737 0.05 0.6283 miRNATAP -0.16 0 NA
41 hsa-miR-27b-3p APAF1 0.24 0.12264 0.05 0.6283 miRNATAP -0.17 0 NA
42 hsa-miR-374b-5p APAF1 0.47 0.01092 0.05 0.6283 mirMAP -0.07 0.01286 NA
43 hsa-miR-664a-3p APAF1 0.44 0.02142 0.05 0.6283 mirMAP -0.11 2.0E-5 NA
44 hsa-miR-125a-3p ATM -1.05 0 0.08 0.53013 miRanda -0.06 0.02074 NA
45 hsa-miR-18a-5p ATM 1.37 1.0E-5 0.08 0.53013 miRNAWalker2 validate; miRTarBase; MirTarget -0.08 0.0004 23437304; 25963391; 23857602; 23229340 MicroRNA 18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer; Through in silico search the 3'UTR of Ataxia telangiectasia mutated ATM contains a conserved miR-18a binding site; Expression of ATM was down-regulated in CRC tumors p<0.0001 and inversely correlated with miR-18a expression r = -0.4562 p<0.01; This was further confirmed by the down-regulation of ATM protein by miR-18a; As ATM is a key enzyme in DNA damage repair we evaluated the effect of miR-18a on DNA double-strand breaks; miR-18a attenuates cellular repair of DNA double-strand breaks by directly suppressing ATM a key enzyme in DNA damage repair;However the upregulation of miR-18a suppressed the level of ataxia-telangiectasia mutated and attenuated DNA double-strand break repair after irradiation which re-sensitized the cervical cancer cells to radiotherapy by promoting apoptosis;Furthermore we used antisense oligonucleotides against micro RNAs miRNA or miRNA overexpression plasmids to study the role of miR-18a and -106a on ATM expression; Furthermore we identified that ERα activates miR-18a and -106a to downregulate ATM expression; We reveal a novel mechanism involving ERα and miR-18a and -106a regulation of ATM in breast cancer;MicroRNA 18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells; Previous studies showed that certain microRNAs including miR-18a potentially regulate ATM in cancer cells; However the mechanisms behind the modulation of ATM by miR-18a remain to be elucidated in colon cancer cells; In the present study we explored the impact of miR-18a on the autophagy process and ATM expression in HCT116 colon cancer cells; Western blotting and luciferase assays were implemented to explore the impact of miR-18a on ATM gene expression in HCT116 cells; Moreover miR-18a overexpression led to the upregulation of ATM expression and suppression of mTORC1 activity; Results of the present study pertaining to the role of miR-18a in regulating autophagy and ATM gene expression in colon cancer cells revealed a novel function for miR-18a in a critical cellular event and on a crucial gene with significant impacts in cancer development progression treatment and in other diseases
46 hsa-miR-590-5p ATM 2.07 0 0.08 0.53013 mirMAP -0.07 0.00604 NA
47 hsa-miR-15a-5p BCL2 1.63 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.19 0.00401 26915294; 25594541; 18931683; 25623762; 22335947 As a result transcript levels of the tumor-suppressive miR-15 and let-7 families increased which targeted and decreased the expression of the crucial prosurvival genes BCL-2 and BCL-XL respectively;MicroRNAs miRNAs encoded by the miR-15 cluster are known to induce G1 arrest and apoptosis by targeting G1 checkpoints and the anti-apoptotic B cell lymphoma 2 BCL-2 gene;MicroRNAs miRNAs are noncoding small RNAs that repress protein translation by targeting specific messenger RNAs miR-15a and miR-16-1 act as putative tumor suppressors by targeting the oncogene BCL2;miR 15a and miR 16 modulate drug resistance by targeting bcl 2 in human colon cancer cells; To investigate the reversal effect of targeted modulation of bcl-2 expression by miR-15a and miR-16 on drug resistance of human colon cancer cells;The expression of MiR-15a was significantly inhibited by Bcl-2 P < 0.05
48 hsa-miR-17-5p BCL2 2.07 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.12 0.02174 25435430 Combined overexpression of miR-16 and miR-17 greatly reduced Beclin-1 and Bcl-2 expressions respectively; miR-17 overexpression reduced cytoprotective autophagy by targeting Beclin-1 whereas overexpression of miR-16 potentiated paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2
49 hsa-miR-200c-3p BCL2 0.38 0.08422 -0.49 0.06421 miRNAWalker2 validate; miRTarBase; mirMAP -0.13 0.02205 NA
50 hsa-miR-20a-3p BCL2 2.52 0 -0.49 0.06421 mirMAP -0.1 0.01974 NA
51 hsa-miR-20a-5p BCL2 2.65 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.12 0.01368 NA
52 hsa-miR-21-5p BCL2 4.38 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.2 1.0E-5 22964582; 21468550; 25994220; 25381586; 26555418; 23359184; 21376256 Tumors harvested from these lungs have elevated levels of oncogenic miRNAs miR-21 and miR-155; are deficient for p53-regulated miRNAs; and have heightened expression of miR-34 target genes such as Met and Bcl-2;BCL-2 up-regulation could be achieved by miR-21 overexpression which prevented T24 cells from apoptosis induced by doxorubicin; Furthermore the miR-21 induced BCL-2 up-regulation could be cancelled by the PI3K inhibitor LY294002;Meanwhile miR-21 loss reduced STAT3 and Bcl-2 activation causing an increase in the apoptosis of tumour cells in CAC mice;Changes in the sensitivity of osteosarcoma cells to CDDP were examined after transfection with miR-21 mimics or anti-miR-21 or bcl-2 siRNA in combination with CDDP;The expression of Bax Bcl-2 and miR-21 in parental and paclitaxel-resistant cells was detected by RT-PCR and Western blotting;Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR 21 regulation of BCL 2 expression; We also used Western blot to measure BCL-2 protein levels after down-regulation of miR-21 expression; Besides down-regulation of miR-21 expression can inhibit BCL-2 expression in PANC-1 CFPAC-1 and MIA Paca-2 cells; Over-expression of miR-21 expression can reverse down-regulation of BCL-2 expression and apoptosis induced by resveratrol; In this study we demonstrated that the effect of resveratrol on apoptosis is due to inhibiting miR-21 regulation of BCL-2 expression;Bcl 2 upregulation induced by miR 21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa 2 pancreatic cancer cells; However the roles and mechanisms of miRNA miR-21 in regulation of Bcl-2 in pancreatic cancer remain to be elucidated; Then luciferase activity was observed after miR-21 mimics and pRL-TK plasmids containing wild-type and mutant 3'UTRs of Bcl-2 mRNA were co-transfected; Cells transfected with miR-21 inhibitor revealed an opposite trend. There was a significant increase in luciferase activity in the cells transfected with the wild-type pRL-TK plasmid in contrast to those transfected with the mutant one indicating that miR-21 promotes Bcl-2 expression by binding directly to the 3'UTR of Bcl-2 mRNA; Upregulation of Bcl-2 directly induced by miR-21 is associated with apoptosis chemoresistance and proliferation of MIA PaCa-2 pancreatic cancer cells
53 hsa-miR-224-5p BCL2 1.92 0 -0.49 0.06421 mirMAP -0.14 0 24796455 In addition the expressions of Bcl2 mRNA and protein were 1.05 ± 0.04 and 0.21 ± 0.03 in the miR-224 ASO group significantly lower than that in the control group 4.87 ± 0.96 and 0.88 ± 0.09 P < 0.01
54 hsa-miR-24-2-5p BCL2 1.44 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.16 0.00352 NA
55 hsa-miR-29a-5p BCL2 1.9 0 -0.49 0.06421 mirMAP -0.24 0 20041405 Subsequent investigation characterized two antiapoptotic molecules Bcl-2 and Mcl-1 as direct targets of miR-29; Furthermore silencing of Bcl-2 and Mcl-1 phenocopied the proapoptotic effect of miR-29 whereas overexpression of these proteins attenuated the effect of miR-29
56 hsa-miR-29b-3p BCL2 3.11 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.1 0.02485 20041405 Subsequent investigation characterized two antiapoptotic molecules Bcl-2 and Mcl-1 as direct targets of miR-29; Furthermore silencing of Bcl-2 and Mcl-1 phenocopied the proapoptotic effect of miR-29 whereas overexpression of these proteins attenuated the effect of miR-29
57 hsa-miR-3065-5p BCL2 0.65 0.09995 -0.49 0.06421 mirMAP -0.12 0.00023 NA
58 hsa-miR-33a-5p BCL2 2.8 0 -0.49 0.06421 mirMAP -0.1 0.00701 NA
59 hsa-miR-34a-5p BCL2 1.41 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.19 0.00135 22964582; 24565525; 23155233; 24444609; 20687223; 22623155; 24988056; 18803879; 19714243; 25053345; 20433755; 21399894; 23862748 Tumors harvested from these lungs have elevated levels of oncogenic miRNAs miR-21 and miR-155; are deficient for p53-regulated miRNAs; and have heightened expression of miR-34 target genes such as Met and Bcl-2;In vitro and in vivo experiments showed that miR-34a and DOX can be efficiently encapsulated into HA-CS NPs and delivered into tumor cells or tumor tissues and enhance anti-tumor effects of DOX by suppressing the expression of non-pump resistance and anti-apoptosis proto-oncogene Bcl-2;The miR-34a expression levels in cells after irradiation at 30 and 60 Gy were 0.17- and 18.7-times the BCL2 and caspase-9 expression levels respectively;Functional analyses further indicate that restoration of miR-34a inhibits B cell lymphoma-2 Bcl-2 protein expression to withdraw the survival advantage of these resistant NSCLC cells;Thus in PC3PR cells reduced expression of miR-34a confers paclitaxel resistance via up-regulating SIRT1 and Bcl2 expression; MiR-34a and its downstream targets SIRT1 and Bcl2 play important roles in the development of paclitaxel resistance all of which can be useful biomarkers and promising therapeutic targets for the drug resistance in hormone-refractory prostate cancer;MiR 34a inhibits proliferation and migration of breast cancer through down regulation of Bcl 2 and SIRT1; In this study we aimed to determine the effect of miR-34a on the growth of breast cancer and to investigate whether its effect is achieved by targeting Bcl-2 and SIRT1; Bcl-2 and SIRT1 as the targets of miR-34a were found to be in reverse correlation with ectopic expression of miR-34a;Target analysis indicated that micro RNA miR-34a directly regulates Bcl-2 and miR-34a overexpression decreased Bcl-2 protein level in gastric cancer cells; We also found that luteolin upregulates miR-34a expression and downregulates Bcl-2 expression; Based on these results we can draw the conclusion that luteolin partly decreases Bcl-2 expression through upregulating miR-34a expression;miR-34 targets Notch HMGA2 and Bcl-2 genes involved in the self-renewal and survival of cancer stem cells; Human gastric cancer cells were transfected with miR-34 mimics or infected with the lentiviral miR-34-MIF expression system and validated by miR-34 reporter assay using Bcl-2 3'UTR reporter; Human gastric cancer Kato III cells with miR-34 restoration reduced the expression of target genes Bcl-2 Notch and HMGA2; Bcl-2 3'UTR reporter assay showed that the transfected miR-34s were functional and confirmed that Bcl-2 is a direct target of miR-34; The mechanism of miR-34-mediated suppression of self-renewal appears to be related to the direct modulation of downstream targets Bcl-2 Notch and HMGA2 indicating that miR-34 may be involved in gastric cancer stem cell self-renewal/differentiation decision-making;Among the target proteins regulated by miR-34 are Notch pathway proteins and Bcl-2 suggesting the possibility of a role for miR-34 in the maintenance and survival of cancer stem cells; Our data support the view that miR-34 may be involved in pancreatic cancer stem cell self-renewal potentially via the direct modulation of downstream targets Bcl-2 and Notch implying that miR-34 may play an important role in pancreatic cancer stem cell self-renewal and/or cell fate determination;Manipulating miR-34a in prostate cancer cells confirms that this miRNA regulates BCL-2 and may in part regulate response to docetaxel;For instance miR-34a up-regulation corresponded with a down-regulation of BCL2 protein; Treating Par-4-overexpressing HT29 cells with a miR-34a antagomir functionally reversed both BCL2 down-regulation and apoptosis by 5-FU;Quantitative PCR and western analysis confirmed decreased expression of two genes BCL-2 and CCND1 in docetaxel-resistant cells which are both targeted by miR-34a;MicroRNA 34a targets Bcl 2 and sensitizes human hepatocellular carcinoma cells to sorafenib treatment; HCC tissues with lower miR-34a expression displayed higher expression of Bcl-2 protein than those with high expression of miR-34a; therefore an inverse correlation is evident between the miR-34a level and Bcl-2 expression; Bioinformatics and luciferase reporter assays revealed that miR-34a binds the 3'-UTR of the Bcl-2 mRNA and represses its translation; Western blotting analysis and qRT-PCR confirmed that Bcl-2 is inhibited by miR-34a overexpression; Functional analyses indicated that the restoration of miR-34a reduced cell viability promoted cell apoptosis and potentiated sorafenib-induced apoptosis and toxicity in HCC cell lines by inhibiting Bcl-2 expression
60 hsa-miR-365a-3p BCL2 0.01 0.9536 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.14 0.01107 NA
61 hsa-miR-450b-5p BCL2 1.69 0 -0.49 0.06421 mirMAP -0.2 0 NA
62 hsa-miR-452-5p BCL2 0.64 0.04582 -0.49 0.06421 mirMAP -0.12 0.00113 NA
63 hsa-miR-542-3p BCL2 1.62 0 -0.49 0.06421 mirMAP -0.19 3.0E-5 NA
64 hsa-miR-590-3p BCL2 0.84 0.00129 -0.49 0.06421 miRanda; mirMAP -0.12 0.02705 NA
65 hsa-miR-590-5p BCL2 2.07 0 -0.49 0.06421 miRanda -0.18 0.00054 NA
66 hsa-miR-96-5p BCL2 3.04 0 -0.49 0.06421 miRNAWalker2 validate; TargetScan -0.14 0.00193 NA
67 hsa-miR-326 BCL2L1 -0.99 0.00335 -0.25 0.07732 PITA; miRanda; mirMAP; miRNATAP -0.06 0.00125 NA
68 hsa-miR-330-5p BCL2L1 0.17 0.33643 -0.25 0.07732 PITA; miRanda; miRNATAP -0.08 0.03195 NA
69 hsa-miR-421 BCL2L1 0.17 0.53528 -0.25 0.07732 miRanda -0.09 0.00056 NA
70 hsa-miR-204-5p BIRC2 -1.02 0.00767 -0.06 0.62026 miRNAWalker2 validate; miRTarBase; MirTarget -0.08 0 NA
71 hsa-miR-29a-3p BIRC2 0.1 0.5732 -0.06 0.62026 MirTarget -0.06 0.04035 NA
72 hsa-miR-29b-3p BIRC2 3.11 0 -0.06 0.62026 MirTarget -0.06 0.00214 NA
73 hsa-miR-500a-5p BIRC2 0.65 0.01047 -0.06 0.62026 MirTarget -0.11 0 NA
74 hsa-miR-624-5p BIRC2 -0.06 0.82985 -0.06 0.62026 MirTarget -0.05 0.02001 NA
75 hsa-miR-24-1-5p BIRC3 0.86 0.00011 0.13 0.67648 MirTarget -0.21 0.00165 NA
76 hsa-miR-375 BIRC3 0.62 0.1492 0.13 0.67648 miRNAWalker2 validate -0.2 0 23726271 Taken together these data suggest that miR-375 sensitizes TNF-α-induced apoptosis and the reduction in the expression of the apoptosis inhibitory proteins cFLIP-L and cIAP2 plays an important role in this sensitization
77 hsa-miR-664a-3p BIRC3 0.44 0.02142 0.13 0.67648 mirMAP -0.17 0.0216 NA
78 hsa-miR-98-5p BIRC3 1.17 0 0.13 0.67648 miRNAWalker2 validate -0.14 0.0476 NA
79 hsa-miR-107 CAPN2 0.66 0 -0.31 0.05176 miRanda -0.13 0.02025 NA
80 hsa-miR-1468-5p CAPN2 -0.9 0.00072 -0.31 0.05176 MirTarget -0.06 0.03764 NA
81 hsa-miR-16-2-3p CAPN2 0.5 0.02636 -0.31 0.05176 mirMAP -0.11 0.00157 NA
82 hsa-miR-20a-3p CAPN2 2.52 0 -0.31 0.05176 MirTarget -0.13 0 NA
83 hsa-miR-320b CAPN2 0.23 0.37882 -0.31 0.05176 miRanda -0.12 1.0E-5 NA
84 hsa-miR-421 CAPN2 0.17 0.53528 -0.31 0.05176 miRanda -0.16 0 NA
85 hsa-miR-590-3p CAPN2 0.84 0.00129 -0.31 0.05176 miRanda -0.1 0.00294 NA
86 hsa-miR-590-5p CAPN2 2.07 0 -0.31 0.05176 miRanda -0.16 0 NA
87 hsa-miR-7-5p CAPN2 0.34 0.43506 -0.31 0.05176 miRNAWalker2 validate -0.08 6.0E-5 NA
88 hsa-miR-129-5p CASP10 -0.41 0.34149 -0.27 0.09806 mirMAP -0.06 0.00151 NA
89 hsa-miR-148b-5p CASP10 1.39 0 -0.27 0.09806 mirMAP -0.14 2.0E-5 NA
90 hsa-miR-19a-3p CASP10 2.12 0 -0.27 0.09806 MirTarget; mirMAP -0.1 6.0E-5 NA
91 hsa-miR-19b-1-5p CASP10 1.71 0 -0.27 0.09806 mirMAP -0.18 0 NA
92 hsa-miR-19b-3p CASP10 2.11 0 -0.27 0.09806 MirTarget; mirMAP -0.12 0.00012 NA
93 hsa-miR-200c-3p CASP10 0.38 0.08422 -0.27 0.09806 mirMAP -0.07 0.048 NA
94 hsa-miR-320b CASP10 0.23 0.37882 -0.27 0.09806 miRanda -0.09 0.00149 NA
95 hsa-miR-421 CASP10 0.17 0.53528 -0.27 0.09806 mirMAP -0.17 0 NA
96 hsa-miR-744-3p CASP10 2.07 0 -0.27 0.09806 mirMAP -0.13 0 NA
97 hsa-let-7a-5p CASP3 -1.37 0 0.75 0 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.09 0.00189 NA
98 hsa-let-7b-5p CASP3 -1.62 0 0.75 0 MirTarget; miRNATAP -0.07 0.01162 NA
99 hsa-let-7c-5p CASP3 -2.14 0 0.75 0 MirTarget -0.07 0.00043 NA
100 hsa-miR-139-5p CASP3 -2.27 0 0.75 0 miRanda -0.1 0 NA
101 hsa-miR-195-3p CASP3 -1.33 0 0.75 0 MirTarget -0.12 0 NA
102 hsa-miR-30a-5p CASP3 -0.92 0.00076 0.75 0 miRNATAP -0.09 0 NA
103 hsa-miR-30c-5p CASP3 -0.33 0.1236 0.75 0 miRNATAP -0.15 0 NA
104 hsa-miR-30d-5p CASP3 -0.92 4.0E-5 0.75 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.17 0 NA
105 hsa-miR-362-3p CASP3 0.19 0.52808 0.75 0 miRanda -0.06 0.00859 NA
106 hsa-miR-374a-5p CASP3 -0.2 0.29808 0.75 0 mirMAP -0.07 0.0379 NA
107 hsa-miR-125a-5p CASP6 -1.05 0 0.9 0 miRanda -0.12 0.00016 NA
108 hsa-miR-106b-5p CASP7 1.47 0 -0.21 0.08139 miRNAWalker2 validate -0.06 0.01907 22986525 MicroRNA 106b 25 cluster expression is associated with early disease recurrence and targets caspase 7 and focal adhesion in human prostate cancer; Moreover increased tumor miR-106b expression was associated with disease recurrence and the combination of high miR-106b and low CASP7 caspase-7 expressions in primary tumors was an independent predictor of early disease recurrence adjusted hazard ratio=4.1; 95% confidence interval: 1.6-12.3; The approach revealed that CASP7 is a direct target of miR-106b which was confirmed by western blot analysis and a 3'-untranslated region reporter assay; Moreover selected phenotypes induced by miR-106b knockdown in DU145 human prostate cancer cells did not develop when both miR-106b and CASP7 expression were inhibited
109 hsa-miR-664a-3p CASP7 0.44 0.02142 -0.21 0.08139 MirTarget -0.11 0.00018 NA
110 hsa-miR-17-5p CASP8 2.07 0 0.38 0.00232 MirTarget -0.07 0.00207 NA
111 hsa-miR-19b-1-5p CASP8 1.71 0 0.38 0.00232 miRNAWalker2 validate -0.07 0.00768 NA
112 hsa-miR-19b-3p CASP8 2.11 0 0.38 0.00232 MirTarget -0.05 0.02505 NA
113 hsa-miR-20a-5p CASP8 2.65 0 0.38 0.00232 MirTarget -0.05 0.02464 NA
114 hsa-miR-93-5p CASP8 1.51 0 0.38 0.00232 MirTarget -0.06 0.01825 NA
115 hsa-miR-195-5p CASP9 -1.02 5.0E-5 -0.03 0.82555 mirMAP -0.06 0.01207 NA
116 hsa-miR-199a-3p CASP9 1.68 0 -0.03 0.82555 mirMAP -0.09 0.00108 23319430 The techniques used were the MTT assay flow cytometry real-time PCR to assess miR-199a expression as also caspase-8 and caspase-9 activity in HepG2 cells treated with Propofol
117 hsa-miR-199b-3p CASP9 1.68 0 -0.03 0.82555 mirMAP -0.09 0.00109 NA
118 hsa-miR-222-5p CASP9 0.1 0.71933 -0.03 0.82555 mirMAP -0.05 0.01673 NA
119 hsa-miR-342-5p CASP9 -0.38 0.0897 -0.03 0.82555 MirTarget -0.07 0.01107 NA
120 hsa-miR-497-5p CASP9 -0.05 0.78621 -0.03 0.82555 mirMAP -0.08 0.00786 NA
121 hsa-miR-107 CFLAR 0.66 0 -0.6 0.00015 miRanda -0.15 0.00732 NA
122 hsa-miR-130b-3p CFLAR 1.83 0 -0.6 0.00015 mirMAP -0.17 0 NA
123 hsa-miR-186-5p CFLAR 0.85 0 -0.6 0.00015 mirMAP -0.11 0.03888 NA
124 hsa-miR-301a-3p CFLAR 2.7 0 -0.6 0.00015 mirMAP -0.06 0.01637 NA
125 hsa-miR-320b CFLAR 0.23 0.37882 -0.6 0.00015 miRanda -0.15 0 NA
126 hsa-miR-330-5p CFLAR 0.17 0.33643 -0.6 0.00015 miRanda -0.11 0.0124 NA
127 hsa-miR-421 CFLAR 0.17 0.53528 -0.6 0.00015 miRanda -0.11 0.00019 NA
128 hsa-miR-454-3p CFLAR 1.49 0 -0.6 0.00015 mirMAP -0.11 0.0011 NA
129 hsa-miR-550a-5p CFLAR 0.6 0.03148 -0.6 0.00015 mirMAP -0.06 0.01426 NA
130 hsa-miR-708-5p CFLAR 3.04 0 -0.6 0.00015 mirMAP -0.1 2.0E-5 NA
131 hsa-miR-106b-5p CHP2 1.47 0 -0.7 0.27547 MirTarget -0.29 0.04606 NA
132 hsa-miR-582-5p CHP2 1.08 0.00149 -0.7 0.27547 miRNATAP -0.17 0.04861 NA
133 hsa-miR-148a-3p CHUK 2.31 0 0.04 0.74424 MirTarget -0.07 0.0015 NA
134 hsa-miR-15a-5p CHUK 1.63 0 0.04 0.74424 miRNAWalker2 validate; miRTarBase; MirTarget -0.16 0 NA
135 hsa-miR-15b-5p CHUK -1.26 0 0.04 0.74424 MirTarget -0.06 0.03926 NA
136 hsa-miR-195-5p CHUK -1.02 5.0E-5 0.04 0.74424 miRNAWalker2 validate; MirTarget -0.06 0.00384 NA
137 hsa-miR-23b-3p CHUK -0.07 0.62059 0.04 0.74424 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.08 0.04582 NA
138 hsa-miR-29b-2-5p CHUK 0.35 0.19484 0.04 0.74424 MirTarget -0.12 0 NA
139 hsa-miR-339-5p CHUK 0.54 0.04881 0.04 0.74424 miRanda -0.1 0 NA
140 hsa-miR-342-3p CHUK -0.13 0.56103 0.04 0.74424 miRanda -0.18 0 NA
141 hsa-miR-362-3p CHUK 0.19 0.52808 0.04 0.74424 miRanda -0.07 0.00121 NA
142 hsa-miR-376c-3p CHUK 0.02 0.95781 0.04 0.74424 MirTarget -0.06 8.0E-5 NA
143 hsa-miR-429 CHUK 2.38 0 0.04 0.74424 miRanda -0.06 0.00053 NA
144 hsa-miR-497-5p CHUK -0.05 0.78621 0.04 0.74424 MirTarget -0.19 0 NA
145 hsa-miR-15b-3p CSF2RB 0.8 0.0004 -1.28 0 mirMAP -0.15 0.00822 NA
146 hsa-miR-181d-5p CSF2RB 1.19 0 -1.28 0 MirTarget -0.23 8.0E-5 NA
147 hsa-miR-19a-3p CSF2RB 2.12 0 -1.28 0 MirTarget -0.17 4.0E-5 NA
148 hsa-miR-19b-3p CSF2RB 2.11 0 -1.28 0 MirTarget -0.25 0 NA
149 hsa-miR-139-5p CYCS -2.27 0 0.53 0.0008 miRanda -0.18 0 NA
150 hsa-miR-200a-3p CYCS 3.15 0 0.53 0.0008 mirMAP -0.06 0.00378 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 POSITIVE REGULATION OF RESPONSE TO STIMULUS 54 1929 1.986e-38 9.239e-35
2 INTRACELLULAR SIGNAL TRANSDUCTION 49 1572 5.008e-36 7.988e-33
3 REGULATION OF CELL DEATH 48 1472 5.15e-36 7.988e-33
4 CELL DEATH 42 1001 4.305e-35 5.007e-32
5 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 49 1848 1.059e-32 9.852e-30
6 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 21 99 6.827e-32 5.294e-29
7 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 45 1492 8.67e-32 5.763e-29
8 POSITIVE REGULATION OF CELL COMMUNICATION 45 1532 2.724e-31 1.584e-28
9 APOPTOTIC SIGNALING PATHWAY 27 289 5.996e-31 3.1e-28
10 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 45 1656 7.799e-30 3.629e-27
11 POSITIVE REGULATION OF MOLECULAR FUNCTION 46 1791 1.396e-29 5.628e-27
12 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 23 179 1.451e-29 5.628e-27
13 RESPONSE TO OXYGEN CONTAINING COMPOUND 42 1381 2.122e-29 7.596e-27
14 NEGATIVE REGULATION OF CELL DEATH 36 872 3.364e-29 1.118e-26
15 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 36 876 3.948e-29 1.225e-26
16 IMMUNE SYSTEM PROCESS 47 1984 8.021e-29 2.333e-26
17 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 24 233 1.789e-28 4.897e-26
18 RESPONSE TO CYTOKINE 33 714 4.143e-28 1.071e-25
19 EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 15 39 2.149e-27 5.263e-25
20 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 22 213 4.172e-26 9.705e-24
21 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 17 95 1.678e-24 3.718e-22
22 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 17 98 2.967e-24 6.024e-22
23 POSITIVE REGULATION OF CATALYTIC ACTIVITY 39 1518 2.978e-24 6.024e-22
24 POSITIVE REGULATION OF CELL DEATH 28 605 1.298e-23 2.516e-21
25 ZYMOGEN ACTIVATION 17 112 3.355e-23 6.245e-21
26 CELLULAR RESPONSE TO CYTOKINE STIMULUS 27 606 2.654e-22 4.749e-20
27 REGULATION OF IMMUNE SYSTEM PROCESS 36 1403 4.177e-22 7.198e-20
28 RESPONSE TO NITROGEN COMPOUND 30 859 7.373e-22 1.183e-19
29 REGULATION OF IMMUNE RESPONSE 30 858 7.131e-22 1.183e-19
30 POSITIVE REGULATION OF IMMUNE RESPONSE 26 563 7.682e-22 1.191e-19
31 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 17 153 8.596e-21 1.29e-18
32 ACTIVATION OF IMMUNE RESPONSE 23 427 8.975e-21 1.305e-18
33 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 17 154 9.636e-21 1.359e-18
34 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 21 321 1.031e-20 1.411e-18
35 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 32 1135 1.293e-20 1.718e-18
36 REGULATION OF PEPTIDASE ACTIVITY 22 392 2.987e-20 3.861e-18
37 CYTOKINE MEDIATED SIGNALING PATHWAY 23 452 3.225e-20 4.055e-18
38 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 13 6.301e-20 7.715e-18
39 RESPONSE TO ABIOTIC STIMULUS 30 1024 1.071e-19 1.278e-17
40 REGULATION OF APOPTOTIC SIGNALING PATHWAY 21 363 1.322e-19 1.538e-17
41 POSITIVE REGULATION OF DEFENSE RESPONSE 21 364 1.4e-19 1.588e-17
42 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 28 867 2.02e-19 2.237e-17
43 REGULATION OF PROTEOLYSIS 26 711 2.619e-19 2.835e-17
44 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 27 799 3.37e-19 3.564e-17
45 RESPONSE TO BIOTIC STIMULUS 28 886 3.577e-19 3.698e-17
46 RESPONSE TO TUMOR NECROSIS FACTOR 18 233 4.279e-19 4.328e-17
47 REGULATION OF PHOSPHORUS METABOLIC PROCESS 35 1618 5.082e-19 5.031e-17
48 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 17 200 8.966e-19 8.691e-17
49 ACTIVATION OF INNATE IMMUNE RESPONSE 17 204 1.259e-18 1.196e-16
50 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 15 132 1.416e-18 1.318e-16
51 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 29 1036 1.828e-18 1.636e-16
52 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 29 1036 1.828e-18 1.636e-16
53 REGULATION OF TRANSFERASE ACTIVITY 28 946 1.998e-18 1.754e-16
54 POSITIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 17 2.117e-18 1.824e-16
55 REGULATION OF KINASE ACTIVITY 26 776 2.26e-18 1.912e-16
56 REGULATION OF PROTEIN MODIFICATION PROCESS 35 1710 2.958e-18 2.458e-16
57 PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 14 109 3.663e-18 2.99e-16
58 PROTEIN MATURATION 18 265 4.321e-18 3.466e-16
59 TOLL LIKE RECEPTOR SIGNALING PATHWAY 13 85 5.798e-18 4.572e-16
60 CELLULAR RESPONSE TO NITROGEN COMPOUND 22 505 6.723e-18 5.214e-16
61 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 17 228 8.406e-18 6.412e-16
62 ACTIVATION OF PROTEIN KINASE ACTIVITY 18 279 1.083e-17 8.126e-16
63 PHOSPHORYLATION 30 1228 1.676e-17 1.238e-15
64 RESPONSE TO BACTERIUM 22 528 1.722e-17 1.252e-15
65 RESPONSE TO ENDOGENOUS STIMULUS 32 1450 1.793e-17 1.283e-15
66 RESPONSE TO EXTERNAL STIMULUS 35 1821 2.158e-17 1.521e-15
67 REGULATION OF RESPONSE TO STRESS 32 1468 2.567e-17 1.782e-15
68 I KAPPAB KINASE NF KAPPAB SIGNALING 12 70 2.754e-17 1.884e-15
69 POSITIVE REGULATION OF INNATE IMMUNE RESPONSE 17 246 3.047e-17 2.055e-15
70 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 10 34 3.596e-17 2.39e-15
71 POSITIVE REGULATION OF KINASE ACTIVITY 21 482 4.321e-17 2.793e-15
72 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 22 4.267e-17 2.793e-15
73 POSITIVE REGULATION OF PROTEOLYSIS 19 363 5.899e-17 3.76e-15
74 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 15 171 7.476e-17 4.701e-15
75 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 14 144 2.035e-16 1.262e-14
76 INFLAMMATORY RESPONSE 20 454 2.217e-16 1.357e-14
77 PROTEIN PHOSPHORYLATION 26 944 2.635e-16 1.592e-14
78 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 20 470 4.309e-16 2.57e-14
79 TUMOR NECROSIS FACTOR MEDIATED SIGNALING PATHWAY 13 118 4.962e-16 2.923e-14
80 REGULATION OF INNATE IMMUNE RESPONSE 18 357 8.375e-16 4.871e-14
81 CELLULAR RESPONSE TO ABIOTIC STIMULUS 16 263 2.164e-15 1.243e-13
82 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 34 1977 2.243e-15 1.273e-13
83 REGULATION OF TUMOR NECROSIS FACTOR MEDIATED SIGNALING PATHWAY 10 50 2.686e-15 1.506e-13
84 REGULATION OF DEFENSE RESPONSE 23 759 2.788e-15 1.544e-13
85 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 17 323 2.892e-15 1.583e-13
86 FC EPSILON RECEPTOR SIGNALING PATHWAY 13 142 5.79e-15 3.097e-13
87 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 21 616 5.772e-15 3.097e-13
88 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 10 55 7.537e-15 3.985e-13
89 CELLULAR RESPONSE TO MECHANICAL STIMULUS 11 80 8.188e-15 4.281e-13
90 REGULATION OF HYDROLASE ACTIVITY 28 1327 1.176e-14 6.079e-13
91 INTRINSIC APOPTOTIC SIGNALING PATHWAY 13 152 1.416e-14 7.238e-13
92 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 17 365 2.162e-14 1.093e-12
93 REGULATION OF NEURON DEATH 15 252 2.454e-14 1.228e-12
94 REGULATION OF CELL PROLIFERATION 29 1496 2.957e-14 1.464e-12
95 RESPONSE TO MECHANICAL STIMULUS 14 210 4.086e-14 2.001e-12
96 NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR SIGNALING PATHWAY 8 28 7.791e-14 3.737e-12
97 RESPONSE TO LIPID 23 888 7.757e-14 3.737e-12
98 IMMUNE RESPONSE 25 1100 9.214e-14 4.375e-12
99 POSITIVE REGULATION OF HYDROLASE ACTIVITY 23 905 1.154e-13 5.425e-12
100 POSITIVE REGULATION OF GENE EXPRESSION 30 1733 1.757e-13 8.175e-12
101 SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 8 33 3.429e-13 1.549e-11
102 EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 8 33 3.429e-13 1.549e-11
103 CYTOPLASMIC PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 8 33 3.429e-13 1.549e-11
104 EXECUTION PHASE OF APOPTOSIS 9 55 4.945e-13 2.212e-11
105 NEURON APOPTOTIC PROCESS 8 35 5.778e-13 2.56e-11
106 CELLULAR RESPONSE TO STRESS 28 1565 6.985e-13 3.066e-11
107 FC RECEPTOR SIGNALING PATHWAY 13 206 7.255e-13 3.155e-11
108 PROTEOLYSIS 25 1208 7.466e-13 3.217e-11
109 CELLULAR RESPONSE TO EXTERNAL STIMULUS 14 264 9.448e-13 4.033e-11
110 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 23 1008 1.084e-12 4.587e-11
111 RESPONSE TO PEPTIDE 16 404 1.649e-12 6.913e-11
112 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 15 360 4.325e-12 1.797e-10
113 REGULATION OF NECROTIC CELL DEATH 7 26 4.863e-12 2.002e-10
114 T CELL RECEPTOR SIGNALING PATHWAY 11 146 7.039e-12 2.873e-10
115 RESPONSE TO HORMONE 21 893 7.484e-12 3.002e-10
116 NEURON DEATH 8 47 7.448e-12 3.002e-10
117 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 12 195 8.024e-12 3.191e-10
118 DEFENSE RESPONSE 24 1231 8.694e-12 3.428e-10
119 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 25 1360 1.009e-11 3.944e-10
120 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 8 49 1.062e-11 4.117e-10
121 RESPONSE TO ORGANIC CYCLIC COMPOUND 21 917 1.233e-11 4.74e-10
122 MYD88 INDEPENDENT TOLL LIKE RECEPTOR SIGNALING PATHWAY 7 30 1.487e-11 5.672e-10
123 REGULATION OF CELLULAR PROTEIN LOCALIZATION 17 552 1.653e-11 6.253e-10
124 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 28 1805 2.173e-11 8.153e-10
125 RESPONSE TO WOUNDING 17 563 2.253e-11 8.386e-10
126 NIK NF KAPPAB SIGNALING 9 83 2.352e-11 8.684e-10
127 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 10 121 2.681e-11 9.745e-10
128 CELLULAR RESPONSE TO PEPTIDE 13 274 2.677e-11 9.745e-10
129 NEGATIVE REGULATION OF CELL COMMUNICATION 23 1192 3.294e-11 1.188e-09
130 INOSITOL LIPID MEDIATED SIGNALING 10 124 3.427e-11 1.227e-09
131 HOMEOSTATIC PROCESS 24 1337 4.88e-11 1.734e-09
132 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 16 514 6.077e-11 2.142e-09
133 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 14 370 8.694e-11 3.042e-09
134 REGULATION OF NEURON APOPTOTIC PROCESS 11 192 1.374e-10 4.77e-09
135 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 15 465 1.593e-10 5.49e-09
136 CELLULAR RESPONSE TO HORMONE STIMULUS 16 552 1.736e-10 5.94e-09
137 REGULATION OF MAP KINASE ACTIVITY 13 319 1.767e-10 6.001e-09
138 WOUND HEALING 15 470 1.848e-10 6.231e-09
139 CELLULAR COMPONENT DISASSEMBLY INVOLVED IN EXECUTION PHASE OF APOPTOSIS 7 43 2.265e-10 7.581e-09
140 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 8 71 2.346e-10 7.796e-09
141 RESPONSE TO INORGANIC SUBSTANCE 15 479 2.404e-10 7.933e-09
142 NEGATIVE REGULATION OF MOLECULAR FUNCTION 21 1079 2.513e-10 8.234e-09
143 CELLULAR GLUCOSE HOMEOSTASIS 8 75 3.676e-10 1.196e-08
144 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 7 46 3.728e-10 1.205e-08
145 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 6 25 3.795e-10 1.218e-08
146 RESPONSE TO INTERLEUKIN 1 9 115 4.573e-10 1.458e-08
147 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 20 1004 4.956e-10 1.569e-08
148 CELLULAR RESPONSE TO BIOTIC STIMULUS 10 163 5.149e-10 1.619e-08
149 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 11 220 5.871e-10 1.833e-08
150 RESPONSE TO OXIDATIVE STRESS 13 352 5.908e-10 1.833e-08
151 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 9 120 6.7e-10 2.065e-08
152 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 12 289 7.664e-10 2.346e-08
153 POSITIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 7 51 7.944e-10 2.416e-08
154 NECROTIC CELL DEATH 6 28 8.002e-10 2.418e-08
155 INTERLEUKIN 1 MEDIATED SIGNALING PATHWAY 5 13 8.141e-10 2.444e-08
156 REGULATION OF CATABOLIC PROCESS 17 731 1.259e-09 3.755e-08
157 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 9 129 1.278e-09 3.788e-08
158 CELLULAR RESPONSE TO INTERLEUKIN 1 8 88 1.347e-09 3.967e-08
159 REGULATION OF PROTEIN LOCALIZATION 19 950 1.384e-09 4.051e-08
160 LIPOPOLYSACCHARIDE MEDIATED SIGNALING PATHWAY 6 31 1.55e-09 4.508e-08
161 RESPONSE TO OXYGEN LEVELS 12 311 1.762e-09 5.092e-08
162 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 6 32 1.902e-09 5.43e-08
163 NEGATIVE REGULATION OF SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 6 32 1.902e-09 5.43e-08
164 POSITIVE REGULATION OF MAPK CASCADE 14 470 1.956e-09 5.551e-08
165 REGULATION OF MAPK CASCADE 16 660 2.31e-09 6.514e-08
166 RESPONSE TO ACID CHEMICAL 12 319 2.347e-09 6.578e-08
167 CELL ACTIVATION 15 568 2.486e-09 6.91e-08
168 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 8 95 2.495e-09 6.91e-08
169 CHEMICAL HOMEOSTASIS 18 874 2.586e-09 7.121e-08
170 T CELL HOMEOSTASIS 6 34 2.806e-09 7.681e-08
171 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 11 258 3.145e-09 8.557e-08
172 ACTIVATION OF PROTEIN KINASE A ACTIVITY 5 17 3.869e-09 1.047e-07
173 AGING 11 264 3.998e-09 1.075e-07
174 NEGATIVE REGULATION OF CATABOLIC PROCESS 10 203 4.342e-09 1.161e-07
175 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 8 103 4.765e-09 1.267e-07
176 POSITIVE REGULATION OF PROTEIN IMPORT 8 104 5.146e-09 1.361e-07
177 POSITIVE REGULATION OF NEURON DEATH 7 67 5.69e-09 1.496e-07
178 INNATE IMMUNE RESPONSE ACTIVATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 8 106 5.99e-09 1.566e-07
179 POSITIVE REGULATION OF TRANSPORT 18 936 7.553e-09 1.963e-07
180 REGULATION OF LIPID METABOLIC PROCESS 11 282 7.939e-09 2.052e-07
181 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 17 829 8.284e-09 2.118e-07
182 REGULATION OF INTRACELLULAR TRANSPORT 15 621 8.267e-09 2.118e-07
183 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 10 218 8.606e-09 2.188e-07
184 RESPONSE TO AMINO ACID 8 112 9.276e-09 2.346e-07
185 REGULATION OF NIK NF KAPPAB SIGNALING 6 42 1.069e-08 2.689e-07
186 LEUKOCYTE DIFFERENTIATION 11 292 1.139e-08 2.848e-07
187 CELLULAR RESPONSE TO CARBOHYDRATE STIMULUS 7 74 1.153e-08 2.869e-07
188 REGULATION OF INFLAMMATORY RESPONSE 11 294 1.222e-08 3.024e-07
189 NECROPTOTIC PROCESS 5 21 1.258e-08 3.096e-07
190 GLUCOSE HOMEOSTASIS 9 170 1.454e-08 3.543e-07
191 CARBOHYDRATE HOMEOSTASIS 9 170 1.454e-08 3.543e-07
192 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 12 381 1.705e-08 4.133e-07
193 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 6 47 2.156e-08 5.198e-07
194 HEMOSTASIS 11 311 2.179e-08 5.226e-07
195 RESPONSE TO TOXIC SUBSTANCE 10 241 2.236e-08 5.336e-07
196 REGULATION OF EXECUTION PHASE OF APOPTOSIS 5 24 2.604e-08 6.181e-07
197 REGULATION OF PROTEIN IMPORT 9 183 2.758e-08 6.514e-07
198 IMMUNE SYSTEM DEVELOPMENT 14 582 2.926e-08 6.877e-07
199 LYMPHOCYTE HOMEOSTASIS 6 50 3.162e-08 7.394e-07
200 RESPONSE TO NICOTINE 6 51 3.573e-08 8.313e-07
201 LEUKOCYTE CELL CELL ADHESION 10 255 3.813e-08 8.826e-07
202 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 7 88 3.901e-08 8.987e-07
203 RESPONSE TO REACTIVE OXYGEN SPECIES 9 191 3.992e-08 9.15e-07
204 RESPONSE TO RADIATION 12 413 4.142e-08 9.447e-07
205 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 9 193 4.367e-08 9.912e-07
206 RESPONSE TO ALKALOID 8 137 4.525e-08 1.018e-06
207 REGULATION OF ORGANELLE ORGANIZATION 19 1178 4.53e-08 1.018e-06
208 LYMPHOCYTE ACTIVATION 11 342 5.746e-08 1.285e-06
209 REGULATION OF NECROPTOTIC PROCESS 4 11 5.9e-08 1.307e-06
210 POSITIVE REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 4 11 5.9e-08 1.307e-06
211 RESPONSE TO DRUG 12 431 6.598e-08 1.455e-06
212 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 29 7.169e-08 1.559e-06
213 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 29 7.169e-08 1.559e-06
214 POSITIVE REGULATION OF NIK NF KAPPAB SIGNALING 5 29 7.169e-08 1.559e-06
215 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 18 1087 7.46e-08 1.614e-06
216 REGULATION OF CELL ADHESION 14 629 7.662e-08 1.65e-06
217 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 23 1784 7.787e-08 1.67e-06
218 POSITIVE REGULATION OF MAP KINASE ACTIVITY 9 207 7.969e-08 1.701e-06
219 PEPTIDYL SERINE MODIFICATION 8 148 8.252e-08 1.745e-06
220 RESPONSE TO TEMPERATURE STIMULUS 8 148 8.252e-08 1.745e-06
221 REGULATION OF ENDOTHELIAL CELL DEVELOPMENT 4 12 8.824e-08 1.831e-06
222 LIPID PHOSPHORYLATION 7 99 8.854e-08 1.831e-06
223 REGULATION OF ESTABLISHMENT OF ENDOTHELIAL BARRIER 4 12 8.824e-08 1.831e-06
224 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 6 59 8.731e-08 1.831e-06
225 POSITIVE REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 4 12 8.824e-08 1.831e-06
226 GLYCEROLIPID BIOSYNTHETIC PROCESS 9 211 9.386e-08 1.932e-06
227 REGULATION OF GLUCOSE TRANSPORT 7 100 9.492e-08 1.946e-06
228 REGULATION OF GLUCOSE IMPORT 6 60 9.672e-08 1.965e-06
229 LEUKOCYTE HOMEOSTASIS 6 60 9.672e-08 1.965e-06
230 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 10 282 9.794e-08 1.981e-06
231 RENAL SYSTEM PROCESS 7 102 1.089e-07 2.193e-06
232 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 22 1672 1.145e-07 2.297e-06
233 MYD88 DEPENDENT TOLL LIKE RECEPTOR SIGNALING PATHWAY 5 32 1.205e-07 2.396e-06
234 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 5 32 1.205e-07 2.396e-06
235 RESPONSE TO COBALT ION 4 13 1.271e-07 2.517e-06
236 REGULATION OF CYTOKINE PRODUCTION 13 563 1.555e-07 3.067e-06
237 REGULATION OF CELLULAR LOCALIZATION 19 1277 1.609e-07 3.159e-06
238 PROTEIN KINASE B SIGNALING 5 34 1.656e-07 3.21e-06
239 RENAL WATER HOMEOSTASIS 5 34 1.656e-07 3.21e-06
240 CELLULAR RESPONSE TO ALKALOID 5 34 1.656e-07 3.21e-06
241 TOLL LIKE RECEPTOR 9 SIGNALING PATHWAY 4 14 1.774e-07 3.426e-06
242 REGULATION OF CYTOPLASMIC TRANSPORT 12 481 2.16e-07 4.136e-06
243 REGULATION OF PROTEIN TARGETING 10 307 2.154e-07 4.136e-06
244 RESPONSE TO CARBOHYDRATE 8 168 2.193e-07 4.165e-06
245 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 8 168 2.193e-07 4.165e-06
246 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 36 2.23e-07 4.218e-06
247 REGULATION OF CELL ACTIVATION 12 484 2.309e-07 4.349e-06
248 PHOSPHOLIPID BIOSYNTHETIC PROCESS 9 235 2.345e-07 4.4e-06
249 T CELL APOPTOTIC PROCESS 4 15 2.413e-07 4.509e-06
250 REGULATION OF MEMBRANE PERMEABILITY 6 70 2.459e-07 4.577e-06
251 NEGATIVE REGULATION OF NEURON DEATH 8 171 2.512e-07 4.656e-06
252 CELLULAR RESPONSE TO GLUCAGON STIMULUS 5 38 2.952e-07 5.45e-06
253 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 11 404 3.065e-07 5.636e-06
254 RESPONSE TO VIRUS 9 247 3.57e-07 6.539e-06
255 REGULATION OF CELL DIFFERENTIATION 20 1492 3.781e-07 6.899e-06
256 REGULATION OF RESPONSE TO WOUNDING 11 413 3.814e-07 6.932e-06
257 LEUKOCYTE ACTIVATION 11 414 3.906e-07 7.072e-06
258 REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 4 17 4.183e-07 7.486e-06
259 ACTIVATION OF NF KAPPAB INDUCING KINASE ACTIVITY 4 17 4.183e-07 7.486e-06
260 REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 4 17 4.183e-07 7.486e-06
261 REGULATION OF TRANSPORT 22 1804 4.291e-07 7.649e-06
262 RESPONSE TO UV 7 126 4.633e-07 8.229e-06
263 POSITIVE REGULATION OF GLUCOSE TRANSPORT 5 42 4.944e-07 8.748e-06
264 LEUKOCYTE MIGRATION 9 259 5.315e-07 9.368e-06
265 LYMPHOCYTE APOPTOTIC PROCESS 4 18 5.363e-07 9.416e-06
266 INSULIN RECEPTOR SIGNALING PATHWAY 6 80 5.472e-07 9.572e-06
267 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 43 5.579e-07 9.722e-06
268 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 19 1395 6.262e-07 1.087e-05
269 MULTICELLULAR ORGANISMAL HOMEOSTASIS 9 272 7.999e-07 1.384e-05
270 CELL DEVELOPMENT 19 1426 8.736e-07 1.505e-05
271 RESPONSE TO ANTIBIOTIC 5 47 8.787e-07 1.509e-05
272 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 17 1152 9.294e-07 1.59e-05
273 RESPONSE TO GLUCAGON 5 48 9.78e-07 1.667e-05
274 CELLULAR RESPONSE TO LIPID 11 457 1.033e-06 1.754e-05
275 NEGATIVE REGULATION OF LIPID CATABOLIC PROCESS 4 21 1.04e-06 1.76e-05
276 SINGLE ORGANISM CELL ADHESION 11 459 1.078e-06 1.817e-05
277 LYMPHOCYTE DIFFERENTIATION 8 209 1.151e-06 1.934e-05
278 POSITIVE REGULATION OF CYTOKINE PRODUCTION 10 370 1.184e-06 1.982e-05
279 RESPONSE TO GAMMA RADIATION 5 50 1.203e-06 2.006e-05
280 CELLULAR HOMEOSTASIS 13 676 1.232e-06 2.047e-05
281 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 10 372 1.243e-06 2.059e-05
282 MITOCHONDRIAL MEMBRANE ORGANIZATION 6 92 1.253e-06 2.068e-05
283 CELLULAR CHEMICAL HOMEOSTASIS 12 570 1.301e-06 2.14e-05
284 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 13 684 1.404e-06 2.3e-05
285 REGULATION OF LIPID CATABOLIC PROCESS 5 52 1.467e-06 2.395e-05
286 REGULATION OF CELL CELL ADHESION 10 380 1.506e-06 2.45e-05
287 POSITIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 4 23 1.53e-06 2.472e-05
288 LEUKOCYTE APOPTOTIC PROCESS 4 23 1.53e-06 2.472e-05
289 REGULATION OF MITOCHONDRION ORGANIZATION 8 218 1.579e-06 2.543e-05
290 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 7 152 1.642e-06 2.635e-05
291 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 9 297 1.657e-06 2.649e-05
292 IMMUNE EFFECTOR PROCESS 11 486 1.878e-06 2.992e-05
293 REGULATION OF HOMOTYPIC CELL CELL ADHESION 9 307 2.175e-06 3.454e-05
294 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 10 397 2.229e-06 3.527e-05
295 MULTICELLULAR ORGANISMAL WATER HOMEOSTASIS 5 58 2.542e-06 4.009e-05
296 DEVELOPMENTAL PROGRAMMED CELL DEATH 4 26 2.561e-06 4.026e-05
297 RESPONSE TO ENDOPLASMIC RETICULUM STRESS 8 233 2.593e-06 4.063e-05
298 REGULATION OF BODY FLUID LEVELS 11 506 2.77e-06 4.324e-05
299 REGULATION OF ENDOTHELIAL CELL DIFFERENTIATION 4 27 2.998e-06 4.65e-05
300 DNA CATABOLIC PROCESS 4 27 2.998e-06 4.65e-05
301 POSITIVE REGULATION OF CELL CELL ADHESION 8 243 3.541e-06 5.474e-05
302 PROTEIN HETEROOLIGOMERIZATION 6 113 4.173e-06 6.43e-05
303 RESPONSE TO METAL ION 9 333 4.222e-06 6.483e-05
304 RESPONSE TO CORTICOSTEROID 7 176 4.349e-06 6.657e-05
305 PROTEIN OLIGOMERIZATION 10 434 4.913e-06 7.496e-05
306 RESPONSE TO KETONE 7 182 5.424e-06 8.248e-05
307 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 6 122 6.501e-06 9.821e-05
308 WATER HOMEOSTASIS 5 70 6.483e-06 9.821e-05
309 MYELOID CELL DIFFERENTIATION 7 189 6.949e-06 0.0001046
310 GLYCEROLIPID METABOLIC PROCESS 9 356 7.241e-06 0.0001087
311 PROTEIN AUTOPHOSPHORYLATION 7 192 7.703e-06 0.0001153
312 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 6 126 7.828e-06 0.0001167
313 NEGATIVE REGULATION OF NECROTIC CELL DEATH 3 11 8.179e-06 0.0001216
314 RESPONSE TO ALCOHOL 9 362 8.281e-06 0.0001227
315 PHOSPHOLIPID METABOLIC PROCESS 9 364 8.655e-06 0.0001278
316 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 11 573 9.026e-06 0.0001329
317 POSITIVE REGULATION OF CELL PROLIFERATION 13 814 9.361e-06 0.0001374
318 B CELL ACTIVATION 6 132 1.022e-05 0.0001496
319 RESPONSE TO GROWTH FACTOR 10 475 1.082e-05 0.0001578
320 REGULATION OF VITAMIN METABOLIC PROCESS 3 12 1.088e-05 0.0001581
321 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 14 957 1.099e-05 0.0001593
322 RESPONSE TO INSULIN 7 205 1.181e-05 0.0001706
323 NEGATIVE REGULATION OF LIPID METABOLIC PROCESS 5 80 1.251e-05 0.0001802
324 MITOCHONDRION ORGANIZATION 11 594 1.264e-05 0.000181
325 ACTIVATION OF MAPK ACTIVITY 6 137 1.265e-05 0.000181
326 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 6 138 1.318e-05 0.0001881
327 LIPID MODIFICATION 7 210 1.38e-05 0.0001964
328 JNK CASCADE 5 82 1.411e-05 0.0001978
329 HEPATOCYTE APOPTOTIC PROCESS 3 13 1.41e-05 0.0001978
330 REGULATION OF PROTEIN MATURATION 5 82 1.411e-05 0.0001978
331 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 12 720 1.411e-05 0.0001978
332 REGULATION OF BICELLULAR TIGHT JUNCTION ASSEMBLY 3 13 1.41e-05 0.0001978
333 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 11 602 1.432e-05 0.0002001
334 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 4 40 1.505e-05 0.0002096
335 PLATELET ACTIVATION 6 142 1.551e-05 0.0002154
336 CELL CELL ADHESION 11 608 1.57e-05 0.0002174
337 CELLULAR RESPONSE TO OXYGEN LEVELS 6 143 1.614e-05 0.0002229
338 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 10 498 1.628e-05 0.0002241
339 PROTEIN COMPLEX BIOGENESIS 15 1132 1.652e-05 0.0002261
340 PROTEIN COMPLEX ASSEMBLY 15 1132 1.652e-05 0.0002261
341 RESPONSE TO IONIZING RADIATION 6 145 1.747e-05 0.0002384
342 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 5 86 1.781e-05 0.0002423
343 REGULATION OF CAMP DEPENDENT PROTEIN KINASE ACTIVITY 3 14 1.79e-05 0.0002428
344 CELLULAR RESPONSE TO INSULIN STIMULUS 6 146 1.816e-05 0.0002457
345 INNATE IMMUNE RESPONSE 11 619 1.854e-05 0.00025
346 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 5 88 1.991e-05 0.0002678
347 RESPONSE TO HEAT 5 89 2.104e-05 0.0002821
348 POSITIVE REGULATION OF CELL ACTIVATION 8 311 2.134e-05 0.0002854
349 REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA 4 44 2.21e-05 0.0002946
350 APOPTOTIC DNA FRAGMENTATION 3 15 2.231e-05 0.0002958
351 NEUROTROPHIN TRK RECEPTOR SIGNALING PATHWAY 3 15 2.231e-05 0.0002958
352 NEGATIVE REGULATION OF CELLULAR CATABOLIC PROCESS 6 156 2.642e-05 0.0003492
353 REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 5 94 2.742e-05 0.0003614
354 REGULATION OF LIPID TRANSPORT 5 95 2.886e-05 0.0003793
355 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 4 48 3.132e-05 0.0004093
356 REGULATION OF LIPID KINASE ACTIVITY 4 48 3.132e-05 0.0004093
357 NEGATIVE REGULATION OF PROTEOLYSIS 8 329 3.188e-05 0.0004156
358 NEGATIVE REGULATION OF ANOIKIS 3 17 3.316e-05 0.000431
359 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 13 926 3.634e-05 0.000471
360 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 9 437 3.666e-05 0.0004738
361 NEGATIVE REGULATION OF PEPTIDASE ACTIVITY 7 245 3.713e-05 0.0004786
362 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 6 167 3.874e-05 0.000498
363 CELL PROLIFERATION 11 672 3.935e-05 0.000503
364 RESPONSE TO EXTRACELLULAR STIMULUS 9 441 3.935e-05 0.000503
365 NEGATIVE REGULATION OF ORGANIC ACID TRANSPORT 3 18 3.969e-05 0.0005046
366 INOSITOL PHOSPHATE MEDIATED SIGNALING 3 18 3.969e-05 0.0005046
367 REGULATION OF AUTOPHAGY 7 249 4.115e-05 0.0005217
368 NEGATIVE REGULATION OF KINASE ACTIVITY 7 250 4.221e-05 0.0005337
369 REGULATION OF T CELL MEDIATED IMMUNITY 4 52 4.308e-05 0.0005433
370 CELLULAR PROCESS INVOLVED IN REPRODUCTION IN MULTICELLULAR ORGANISM 7 252 4.44e-05 0.0005583
371 RESPONSE TO MUSCLE STRETCH 3 19 4.701e-05 0.0005771
372 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 4 53 4.647e-05 0.0005771
373 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 9 450 4.602e-05 0.0005771
374 NEGATIVE REGULATION OF MEIOTIC CELL CYCLE 3 19 4.701e-05 0.0005771
375 REGULATION OF CELL CYCLE 13 949 4.68e-05 0.0005771
376 CELLULAR RESPONSE TO AMINO ACID STIMULUS 4 53 4.647e-05 0.0005771
377 POSITIVE REGULATION OF PROTEIN EXPORT FROM NUCLEUS 3 19 4.701e-05 0.0005771
378 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 4 53 4.647e-05 0.0005771
379 DNA CATABOLIC PROCESS ENDONUCLEOLYTIC 3 19 4.701e-05 0.0005771
380 STRIATED MUSCLE CELL DIFFERENTIATION 6 173 4.719e-05 0.0005778
381 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 11 689 4.934e-05 0.0006025
382 CELLULAR RESPONSE TO ACID CHEMICAL 6 175 5.031e-05 0.0006105
383 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 8 351 5.038e-05 0.0006105
384 HOMEOSTASIS OF NUMBER OF CELLS 6 175 5.031e-05 0.0006105
385 MITOCHONDRIAL TRANSPORT 6 177 5.36e-05 0.0006478
386 RESPONSE TO HYDROGEN PEROXIDE 5 109 5.587e-05 0.0006734
387 RESPONSE TO NITRIC OXIDE 3 21 6.417e-05 0.0007715
388 REGULATION OF MYELOID CELL DIFFERENTIATION 6 183 6.45e-05 0.0007735
389 POSITIVE REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 4 58 6.638e-05 0.0007931
390 CELLULAR RESPONSE TO OXIDATIVE STRESS 6 184 6.648e-05 0.0007931
391 REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 5 114 6.919e-05 0.0008233
392 REGULATION OF MONOOXYGENASE ACTIVITY 4 60 7.586e-05 0.0009005
393 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 14 1142 7.685e-05 0.0009099
394 PROTEIN DEPHOSPHORYLATION 6 190 7.939e-05 0.0009375
395 REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 4 61 8.096e-05 0.0009536
396 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 5 118 8.151e-05 0.0009554
397 POSITIVE REGULATION OF CELL ADHESION 8 376 8.151e-05 0.0009554
398 NEUROTROPHIN SIGNALING PATHWAY 3 23 8.499e-05 0.0009936
399 RESPONSE TO LIGHT STIMULUS 7 280 8.613e-05 0.001004
400 REGULATION OF ANOIKIS 3 24 9.687e-05 0.001127
401 RESPONSE TO STEROID HORMONE 9 497 9.851e-05 0.001143
402 REGULATION OF ADAPTIVE IMMUNE RESPONSE 5 123 9.92e-05 0.001145
403 T CELL DIFFERENTIATION 5 123 9.92e-05 0.001145
404 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 4 65 0.0001038 0.001196
405 CELLULAR EXTRAVASATION 3 25 0.0001098 0.001255
406 APOPTOTIC NUCLEAR CHANGES 3 25 0.0001098 0.001255
407 EPITHELIAL CELL APOPTOTIC PROCESS 3 25 0.0001098 0.001255
408 POSITIVE REGULATION OF LIPID BIOSYNTHETIC PROCESS 4 66 0.0001102 0.001257
409 GLAND DEVELOPMENT 8 395 0.0001147 0.001305
410 EMBRYO DEVELOPMENT 12 894 0.000115 0.001305
411 CELLULAR RESPONSE TO DRUG 4 67 0.0001169 0.001323
412 REGULATION OF LIPID BIOSYNTHETIC PROCESS 5 128 0.0001197 0.001346
413 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 5 128 0.0001197 0.001346
414 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 5 128 0.0001197 0.001346
415 REGULATION OF LEUKOCYTE PROLIFERATION 6 206 0.0001238 0.001382
416 NEGATIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 4 68 0.0001239 0.001382
417 NEGATIVE REGULATION OF LIPID TRANSPORT 3 26 0.0001238 0.001382
418 NUCLEAR IMPORT 5 129 0.0001242 0.001382
419 CELLULAR COMPONENT DISASSEMBLY 9 515 0.0001289 0.001431
420 POSITIVE REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 4 69 0.0001311 0.001452
421 TISSUE DEVELOPMENT 16 1518 0.0001315 0.001453
422 POSITIVE REGULATION OF TYPE I INTERFERON PRODUCTION 4 70 0.0001387 0.001527
423 REGULATION OF FATTY ACID TRANSPORT 3 27 0.0001389 0.001527
424 CELLULAR LIPID METABOLIC PROCESS 12 913 0.0001401 0.001537
425 PROTEIN COMPLEX SUBUNIT ORGANIZATION 16 1527 0.0001409 0.001542
426 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 5 135 0.0001537 0.001679
427 POSITIVE REGULATION OF ACUTE INFLAMMATORY RESPONSE 3 28 0.0001551 0.00169
428 POSITIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE 4 73 0.0001632 0.001774
429 CELLULAR RESPONSE TO RADIATION 5 137 0.0001647 0.001786
430 RESPONSE TO ESTROGEN 6 218 0.0001685 0.001823
431 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 4 74 0.000172 0.00185
432 PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION 3 29 0.0001725 0.00185
433 MUSCLE ADAPTATION 3 29 0.0001725 0.00185
434 POSITIVE REGULATION OF MONOOXYGENASE ACTIVITY 3 29 0.0001725 0.00185
435 POSITIVE REGULATION OF LOCOMOTION 8 420 0.0001746 0.001867
436 REGULATION OF HEMOPOIESIS 7 314 0.0001751 0.001867
437 INTERSPECIES INTERACTION BETWEEN ORGANISMS 10 662 0.0001758 0.001867
438 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 10 662 0.0001758 0.001867
439 GRANULOCYTE MIGRATION 4 75 0.0001812 0.001918
440 LIPID BIOSYNTHETIC PROCESS 9 539 0.0001813 0.001918
441 MACROMOLECULAR COMPLEX ASSEMBLY 15 1398 0.0001825 0.001925
442 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 9 541 0.0001864 0.001954
443 REGULATION OF IMMUNE EFFECTOR PROCESS 8 424 0.0001863 0.001954
444 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 9 541 0.0001864 0.001954
445 NEGATIVE REGULATION OF B CELL ACTIVATION 3 30 0.0001912 0.001999
446 EPITHELIUM DEVELOPMENT 12 945 0.000193 0.002014
447 LYMPHOCYTE COSTIMULATION 4 78 0.0002109 0.002193
448 POSITIVE REGULATION OF INTERLEUKIN 2 PRODUCTION 3 31 0.0002111 0.002193
449 NEGATIVE REGULATION OF CELL CYCLE 8 433 0.0002148 0.002226
450 RESPONSE TO ESTRADIOL 5 146 0.0002215 0.002291
451 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 9 554 0.0002224 0.002294
452 POSITIVE REGULATION OF T CELL MEDIATED IMMUNITY 3 32 0.0002323 0.002392
453 REGULATION OF CELL CYCLE PROCESS 9 558 0.0002345 0.002409
454 REGULATION OF LEUKOCYTE DIFFERENTIATION 6 232 0.0002359 0.002417
455 POSITIVE REGULATION OF CELL DIFFERENTIATION 11 823 0.0002366 0.00242
456 REGULATION OF CELLULAR RESPONSE TO STRESS 10 691 0.0002481 0.002532
457 REGULATION OF PROTEIN EXPORT FROM NUCLEUS 3 33 0.0002549 0.002589
458 NEGATIVE REGULATION OF ANION TRANSPORT 3 33 0.0002549 0.002589
459 MUSCLE CELL DIFFERENTIATION 6 237 0.0002645 0.002681
460 SYSTEM PROCESS 17 1785 0.0002651 0.002682
461 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 12 983 0.0002773 0.002799
462 PEPTIDYL AMINO ACID MODIFICATION 11 841 0.0002849 0.002863
463 REGULATION OF DNA METABOLIC PROCESS 7 340 0.0002843 0.002863
464 REPRODUCTION 14 1297 0.0002913 0.002922
465 PROTEIN IMPORT 5 155 0.0002922 0.002924
466 POSITIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 4 85 0.0002935 0.00293
467 REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 5 156 0.0003011 0.002993
468 PROTEIN LOCALIZATION TO NUCLEUS 5 156 0.0003011 0.002993
469 NEGATIVE REGULATION OF PROTEIN PROCESSING 3 35 0.0003041 0.003011
470 NEGATIVE REGULATION OF PROTEIN MATURATION 3 35 0.0003041 0.003011
471 NEGATIVE REGULATION OF TRANSPORT 8 458 0.0003135 0.003097
472 REGULATION OF JNK CASCADE 5 159 0.0003287 0.00324
473 B CELL DIFFERENTIATION 4 89 0.0003499 0.003435
474 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 4 89 0.0003499 0.003435
475 RESPONSE TO NERVE GROWTH FACTOR 3 37 0.0003591 0.003517
476 REGULATION OF OXIDOREDUCTASE ACTIVITY 4 90 0.0003652 0.003562
477 CALCIUM MEDIATED SIGNALING 4 90 0.0003652 0.003562
478 NEGATIVE REGULATION OF GENE EXPRESSION 15 1493 0.0003713 0.003614
479 GAMETE GENERATION 9 595 0.0003757 0.003649
480 ESTABLISHMENT OF LOCALIZATION IN CELL 16 1676 0.000406 0.003936
481 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 3 39 0.0004201 0.004047
482 ERBB2 SIGNALING PATHWAY 3 39 0.0004201 0.004047
483 SPLEEN DEVELOPMENT 3 39 0.0004201 0.004047
484 BIOLOGICAL ADHESION 12 1032 0.0004309 0.004143
485 NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY 5 170 0.0004466 0.004285
486 FC GAMMA RECEPTOR SIGNALING PATHWAY 4 95 0.0004486 0.004295
487 REGULATION OF MEIOTIC CELL CYCLE 3 40 0.0004529 0.004318
488 REGULATION OF ACTIVATED T CELL PROLIFERATION 3 40 0.0004529 0.004318
489 MYELOID LEUKOCYTE DIFFERENTIATION 4 96 0.0004668 0.004432
490 FEMALE GAMETE GENERATION 4 96 0.0004668 0.004432
491 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 10 750 0.0004743 0.004495
492 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 9 616 0.0004831 0.004569
493 REGULATION OF LIPID STORAGE 3 41 0.0004873 0.004581
494 MITOTIC SPINDLE ASSEMBLY 3 41 0.0004873 0.004581
495 MICROTUBULE CYTOSKELETON ORGANIZATION INVOLVED IN MITOSIS 3 41 0.0004873 0.004581
496 SINGLE ORGANISM CELLULAR LOCALIZATION 11 898 0.0004963 0.004656
497 MEMBRANE ORGANIZATION 11 899 0.000501 0.00469
498 MYELOID LEUKOCYTE MIGRATION 4 99 0.0005245 0.0049
499 MYELOID LEUKOCYTE MEDIATED IMMUNITY 3 43 0.0005612 0.005222
500 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 3 43 0.0005612 0.005222
501 REGULATION OF CELLULAR COMPONENT BIOGENESIS 10 767 0.0005647 0.005245
502 MULTICELLULAR ORGANISM REPRODUCTION 10 768 0.0005705 0.005288
503 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 7 387 0.0006167 0.005704
504 REGULATION OF INTERLEUKIN 6 PRODUCTION 4 104 0.0006317 0.00582
505 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 4 104 0.0006317 0.00582
506 POSITIVE REGULATION OF INTERLEUKIN 8 PRODUCTION 3 45 0.0006418 0.005855
507 THYMOCYTE AGGREGATION 3 45 0.0006418 0.005855
508 T CELL DIFFERENTIATION IN THYMUS 3 45 0.0006418 0.005855
509 MACROMOLECULE CATABOLIC PROCESS 11 926 0.000641 0.005855
510 REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 3 45 0.0006418 0.005855
511 MUSCLE SYSTEM PROCESS 6 282 0.0006643 0.006049
512 REGULATION OF PROTEIN CATABOLIC PROCESS 7 393 0.0006752 0.006136
513 PEPTIDYL THREONINE MODIFICATION 3 46 0.0006847 0.006211
514 DEPHOSPHORYLATION 6 286 0.000715 0.006472
515 REGULATION OF CELL CYCLE ARREST 4 108 0.0007279 0.006564
516 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 4 108 0.0007279 0.006564
517 POSITIVE REGULATION OF OXIDOREDUCTASE ACTIVITY 3 47 0.0007294 0.006565
518 REGULATION OF CERAMIDE BIOSYNTHETIC PROCESS 2 11 0.0007466 0.006681
519 POSITIVE REGULATION OF HAIR CYCLE 2 11 0.0007466 0.006681
520 REGULATION OF FEVER GENERATION 2 11 0.0007466 0.006681
521 REGULATION OF NF KAPPAB IMPORT INTO NUCLEUS 3 48 0.000776 0.006904
522 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 3 48 0.000776 0.006904
523 REGULATION OF INTERLEUKIN 2 PRODUCTION 3 48 0.000776 0.006904
524 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 10 801 0.000789 0.007006
525 REGULATION OF TYPE I INTERFERON PRODUCTION 4 111 0.0008067 0.007149
526 REGULATION OF TOLL LIKE RECEPTOR SIGNALING PATHWAY 3 49 0.0008244 0.007279
527 REGULATION OF STEROID BIOSYNTHETIC PROCESS 3 49 0.0008244 0.007279
528 REPRODUCTIVE SYSTEM DEVELOPMENT 7 408 0.0008411 0.007412
529 LOCOMOTION 12 1114 0.0008482 0.00746
530 POSITIVE REGULATION OF INFLAMMATORY RESPONSE 4 113 0.0008624 0.007571
531 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 5 197 0.0008702 0.007626
532 REGULATION OF ORGANIC ACID TRANSPORT 3 50 0.0008746 0.007636
533 POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 3 50 0.0008746 0.007636
534 REGULATION OF CHEMOKINE BIOSYNTHETIC PROCESS 2 12 0.0008938 0.00773
535 I KAPPAB PHOSPHORYLATION 2 12 0.0008938 0.00773
536 REPLICATIVE SENESCENCE 2 12 0.0008938 0.00773
537 MYELIN MAINTENANCE 2 12 0.0008938 0.00773
538 POSITIVE REGULATION OF INTERLEUKIN 2 BIOSYNTHETIC PROCESS 2 12 0.0008938 0.00773
539 REGULATION OF INTERLEUKIN 12 PRODUCTION 3 51 0.0009268 0.008001
540 CELLULAR RESPONSE TO IONIZING RADIATION 3 52 0.0009809 0.008421
541 POSITIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY 3 52 0.0009809 0.008421
542 ACTIVATION OF MAPKK ACTIVITY 3 52 0.0009809 0.008421
543 PLASMA MEMBRANE ORGANIZATION 5 203 0.0009952 0.008528
544 NEGATIVE REGULATION OF PHOSPHORYLATION 7 422 0.001024 0.008755
545 NEGATIVE REGULATION OF AUTOPHAGY 3 53 0.001037 0.008853
546 REGULATION OF SPHINGOLIPID BIOSYNTHETIC PROCESS 2 13 0.001054 0.008882
547 REGULATION OF MEMBRANE LIPID METABOLIC PROCESS 2 13 0.001054 0.008882
548 POSITIVE REGULATION OF STEROID BIOSYNTHETIC PROCESS 2 13 0.001054 0.008882
549 REGULATION OF HISTONE PHOSPHORYLATION 2 13 0.001054 0.008882
550 GLUCOSE METABOLIC PROCESS 4 119 0.001046 0.008882
551 REGULATION OF PROTEIN POLYUBIQUITINATION 2 13 0.001054 0.008882
552 POSITIVE REGULATION OF MACROPHAGE DIFFERENTIATION 2 13 0.001054 0.008882
553 CYTOKINE PRODUCTION 4 120 0.001079 0.009075
554 CELL MOTILITY 10 835 0.001082 0.009075
555 LOCALIZATION OF CELL 10 835 0.001082 0.009075
556 NEGATIVE REGULATION OF REPRODUCTIVE PROCESS 3 54 0.001095 0.009131
557 REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 3 54 0.001095 0.009131
558 REGULATION OF CELL DEVELOPMENT 10 836 0.001092 0.009131
559 REGULATION OF B CELL ACTIVATION 4 121 0.001112 0.00926
560 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 5 209 0.001133 0.009397
561 GERM CELL DEVELOPMENT 5 209 0.001133 0.009397
562 REGULATION OF B CELL PROLIFERATION 3 55 0.001155 0.009564
563 LIPID METABOLIC PROCESS 12 1158 0.001186 0.009804
NumGOOverlapSizeP ValueAdj. P Value
1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY BINDING 11 47 1.5e-17 1.393e-14
2 CYTOKINE RECEPTOR BINDING 17 271 1.554e-16 7.219e-14
3 KINASE ACTIVITY 24 842 2.336e-15 7.235e-13
4 ENZYME BINDING 32 1737 3.216e-15 7.47e-13
5 CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC PROCESS 7 15 4.916e-14 9.134e-12
6 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 24 992 8.568e-14 1.327e-11
7 DEATH RECEPTOR BINDING 7 18 2.409e-13 3.198e-11
8 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 8 43 3.476e-12 4.036e-10
9 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 9 70 4.836e-12 4.992e-10
10 PROTEIN SERINE THREONINE KINASE ACTIVITY 16 445 7.092e-12 6.589e-10
11 PROTEIN KINASE ACTIVITY 18 640 1.705e-11 1.131e-09
12 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 8 51 1.49e-11 1.131e-09
13 UBIQUITIN LIKE PROTEIN LIGASE BINDING 13 264 1.681e-11 1.131e-09
14 TUMOR NECROSIS FACTOR RECEPTOR BINDING 7 30 1.487e-11 1.131e-09
15 KINASE BINDING 17 606 7.101e-11 4.398e-09
16 PROTEIN HETERODIMERIZATION ACTIVITY 15 468 1.742e-10 1.009e-08
17 PROTEASE BINDING 9 104 1.846e-10 1.009e-08
18 IDENTICAL PROTEIN BINDING 22 1209 3.028e-10 1.481e-08
19 DEATH RECEPTOR ACTIVITY 6 24 2.893e-10 1.481e-08
20 ADENYL NUCLEOTIDE BINDING 24 1514 6.224e-10 2.891e-08
21 CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 8 86 1.119e-09 4.949e-08
22 RECEPTOR BINDING 22 1476 1.233e-08 5.206e-07
23 PROTEIN DIMERIZATION ACTIVITY 19 1149 3.048e-08 1.229e-06
24 KINASE REGULATOR ACTIVITY 9 186 3.175e-08 1.229e-06
25 RIBONUCLEOTIDE BINDING 24 1860 3.606e-08 1.34e-06
26 ENZYME REGULATOR ACTIVITY 17 959 6.971e-08 2.491e-06
27 INTERLEUKIN 1 RECEPTOR BINDING 4 16 3.208e-07 1.064e-05
28 PHOSPHATIDYLINOSITOL PHOSPHATE KINASE ACTIVITY 4 16 3.208e-07 1.064e-05
29 PROTEIN PHOSPHATASE BINDING 7 120 3.323e-07 1.065e-05
30 MOLECULAR FUNCTION REGULATOR 19 1353 3.928e-07 1.216e-05
31 CYSTEINE TYPE PEPTIDASE ACTIVITY 8 184 4.394e-07 1.317e-05
32 PROTEIN DOMAIN SPECIFIC BINDING 13 624 5.022e-07 1.414e-05
33 CYSTEINE TYPE ENDOPEPTIDASE REGULATOR ACTIVITY INVOLVED IN APOPTOTIC PROCESS 5 42 4.944e-07 1.414e-05
34 PHOSPHATASE BINDING 7 162 2.512e-06 6.863e-05
35 SIGNAL TRANSDUCER ACTIVITY 20 1731 3.845e-06 0.0001021
36 PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY 4 30 4.642e-06 0.0001198
37 INSULIN RECEPTOR SUBSTRATE BINDING 3 11 8.179e-06 0.0002054
38 PROTEIN KINASE A BINDING 4 42 1.832e-05 0.0004365
39 NEUROTROPHIN RECEPTOR BINDING 3 14 1.79e-05 0.0004365
40 PROTEIN KINASE A CATALYTIC SUBUNIT BINDING 3 15 2.231e-05 0.0005182
41 PROTEIN COMPLEX BINDING 13 935 4.016e-05 0.00091
42 PROTEIN HOMODIMERIZATION ACTIVITY 11 722 7.508e-05 0.001661
43 CAMP BINDING 3 23 8.499e-05 0.001755
44 CYSTEINE TYPE ENDOPEPTIDASE INHIBITOR ACTIVITY INVOLVED IN APOPTOTIC PROCESS 3 23 8.499e-05 0.001755
45 ENZYME INHIBITOR ACTIVITY 8 378 8.458e-05 0.001755
46 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 4 64 9.773e-05 0.001974
47 GROWTH FACTOR RECEPTOR BINDING 5 129 0.0001242 0.002455
48 PEPTIDASE REGULATOR ACTIVITY 6 214 0.0001524 0.002941
49 PROTEIN PHOSPHATASE 2A BINDING 3 28 0.0001551 0.002941
50 MACROMOLECULAR COMPLEX BINDING 15 1399 0.0001839 0.003417
51 ENDOPEPTIDASE ACTIVITY 8 448 0.0002703 0.004924
52 CYCLIC NUCLEOTIDE BINDING 3 36 0.0003308 0.005911
53 HEAT SHOCK PROTEIN BINDING 4 89 0.0003499 0.00602
54 KINASE INHIBITOR ACTIVITY 4 89 0.0003499 0.00602
55 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 5 178 0.0005507 0.009302
NumGOOverlapSizeP ValueAdj. P Value
1 TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS 17 237 1.622e-17 5.562e-15
2 MEMBRANE MICRODOMAIN 18 288 1.905e-17 5.562e-15
3 CATALYTIC COMPLEX 26 1038 2.544e-15 4.722e-13
4 PHOSPHATIDYLINOSITOL 3 KINASE COMPLEX 8 20 3.234e-15 4.722e-13
5 MEMBRANE PROTEIN COMPLEX 23 1020 1.384e-12 1.616e-10
6 TRANSFERASE COMPLEX 18 703 7.927e-11 7.715e-09
7 PROTEIN KINASE COMPLEX 8 90 1.615e-09 1.347e-07
8 CILIARY BASE 5 23 2.067e-08 1.509e-06
9 MEMBRANE REGION 19 1134 2.471e-08 1.603e-06
10 PLASMA MEMBRANE PROTEIN COMPLEX 13 510 4.952e-08 2.892e-06
11 CD40 RECEPTOR COMPLEX 4 11 5.9e-08 3.132e-06
12 CYTOSOLIC PART 9 223 1.504e-07 7.319e-06
13 RECEPTOR COMPLEX 9 327 3.642e-06 0.0001636
14 EXTRINSIC COMPONENT OF MEMBRANE 8 252 4.63e-06 0.0001931
15 IKAPPAB KINASE COMPLEX 3 11 8.179e-06 0.0003184
16 INTRINSIC COMPONENT OF PLASMA MEMBRANE 18 1649 2.855e-05 0.001042
17 PHOSPHATASE COMPLEX 4 48 3.132e-05 0.001076
18 PLASMA MEMBRANE RECEPTOR COMPLEX 6 175 5.031e-05 0.001632
19 MITOCHONDRION 16 1633 0.0003035 0.008963
20 PLASMA MEMBRANE RAFT 4 86 0.0003069 0.008963

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04210_Apoptosis 75 89 5.759e-198 1.019e-195
2 hsa04380_Osteoclast_differentiation 27 128 4.502e-41 3.984e-39
3 hsa04620_Toll.like_receptor_signaling_pathway 24 102 1.092e-37 6.442e-36
4 hsa04660_T_cell_receptor_signaling_pathway 24 108 5.065e-37 2.236e-35
5 hsa04662_B_cell_receptor_signaling_pathway 22 75 6.316e-37 2.236e-35
6 hsa04010_MAPK_signaling_pathway 29 268 3.07e-35 9.057e-34
7 hsa04722_Neurotrophin_signaling_pathway 24 127 3.679e-35 9.302e-34
8 hsa04650_Natural_killer_cell_mediated_cytotoxicity 22 136 1.34e-30 2.965e-29
9 hsa04370_VEGF_signaling_pathway 17 76 2.635e-26 5.182e-25
10 hsa04062_Chemokine_signaling_pathway 20 189 5.913e-24 1.047e-22
11 hsa04910_Insulin_signaling_pathway 18 138 2.745e-23 4.417e-22
12 hsa04914_Progesterone.mediated_oocyte_maturation 14 87 1.316e-19 1.941e-18
13 hsa04920_Adipocytokine_signaling_pathway 13 68 2.586e-19 3.52e-18
14 hsa04621_NOD.like_receptor_signaling_pathway 12 59 2.992e-18 3.783e-17
15 hsa04973_Carbohydrate_digestion_and_absorption 11 44 6.663e-18 7.862e-17
16 hsa04510_Focal_adhesion 16 200 2.779e-17 3.074e-16
17 hsa04622_RIG.I.like_receptor_signaling_pathway 12 71 3.304e-17 3.44e-16
18 hsa04150_mTOR_signaling_pathway 11 52 5.126e-17 5.04e-16
19 hsa04664_Fc_epsilon_RI_signaling_pathway 12 79 1.291e-16 1.203e-15
20 hsa04630_Jak.STAT_signaling_pathway 13 155 1.828e-14 1.618e-13
21 hsa04012_ErbB_signaling_pathway 11 87 2.144e-14 1.807e-13
22 hsa04666_Fc_gamma_R.mediated_phagocytosis 11 95 5.838e-14 4.697e-13
23 hsa04960_Aldosterone.regulated_sodium_reabsorption 8 42 2.838e-12 2.184e-11
24 hsa04115_p53_signaling_pathway 9 69 4.227e-12 3.117e-11
25 hsa04720_Long.term_potentiation 8 70 2.088e-10 1.478e-09
26 hsa04070_Phosphatidylinositol_signaling_system 8 78 5.063e-10 3.447e-09
27 hsa04623_Cytosolic_DNA.sensing_pathway 7 56 1.568e-09 1.028e-08
28 hsa04310_Wnt_signaling_pathway 9 151 5.153e-09 3.257e-08
29 hsa04114_Oocyte_meiosis 8 114 1.067e-08 6.514e-08
30 hsa04670_Leukocyte_transendothelial_migration 8 117 1.311e-08 7.733e-08
31 hsa04020_Calcium_signaling_pathway 8 177 3.27e-07 1.867e-06
32 hsa04810_Regulation_of_actin_cytoskeleton 8 214 1.375e-06 7.604e-06
33 hsa00562_Inositol_phosphate_metabolism 4 57 6.198e-05 0.0003324
34 hsa04360_Axon_guidance 5 130 0.0001288 0.0006704
35 hsa04640_Hematopoietic_cell_lineage 4 88 0.0003351 0.001695
36 hsa04962_Vasopressin.regulated_water_reabsorption 3 44 0.0006006 0.002953
37 hsa04742_Taste_transduction 3 52 0.0009809 0.004693
38 hsa04340_Hedgehog_signaling_pathway 3 56 0.001217 0.00567
39 hsa04976_Bile_secretion 3 71 0.002411 0.01094
40 hsa04971_Gastric_acid_secretion 3 74 0.002712 0.012
41 hsa04970_Salivary_secretion 3 89 0.004565 0.01971
42 hsa04540_Gap_junction 3 90 0.00471 0.01985
43 hsa04912_GnRH_signaling_pathway 3 101 0.006488 0.0261
44 hsa04916_Melanogenesis 3 101 0.006488 0.0261
45 hsa04270_Vascular_smooth_muscle_contraction 3 116 0.009482 0.03729
46 hsa04530_Tight_junction 3 133 0.01371 0.05274
47 hsa04120_Ubiquitin_mediated_proteolysis 3 139 0.01541 0.05805
48 hsa04141_Protein_processing_in_endoplasmic_reticulum 3 168 0.0253 0.0933
49 hsa04110_Cell_cycle 2 128 0.08341 0.3013
50 hsa04740_Olfactory_transduction 3 388 0.1783 0.619

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

TBX5-AS1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-450b-5p;hsa-miR-542-3p;hsa-miR-590-5p;hsa-miR-629-3p 23 PIK3R1 Sponge network -2.108 0 -1.285 0 0.544
2

AC109642.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-3607-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p 23 PIK3R1 Sponge network -2.791 0 -1.285 0 0.529
3

RP11-389C8.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-429;hsa-miR-542-3p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 22 PIK3R1 Sponge network -2.039 0 -1.285 0 0.52
4

LINC00968

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 24 PIK3R1 Sponge network -4.19 0 -1.285 0 0.51
5

RP11-672A2.4

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-424-5p 10 AKT3 Sponge network -2.68 0 -1.44 0 0.497
6 RP11-720L2.4 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-93-5p 14 PIK3R1 Sponge network -2.305 0 -1.285 0 0.496
7

LINC00702

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-374a-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-582-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 29 PIK3R1 Sponge network -2.856 0 -1.285 0 0.494
8

MAGI2-AS3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-429;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 25 PIK3R1 Sponge network -1.892 0 -1.285 0 0.486
9

LINC00702

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-424-5p;hsa-miR-93-5p 14 AKT3 Sponge network -2.856 0 -1.44 0 0.485
10

RP11-815I9.4

 hsa-miR-106a-5p;hsa-miR-148a-3p;hsa-miR-155-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-29a-5p;hsa-miR-590-5p 10 PRKAR2A Sponge network -0.881 0.0002 -0.542 0.00821 0.477
11

LINC00472

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-93-5p 15 PIK3R1 Sponge network -2.952 0 -1.285 0 0.458
12

FENDRR

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-3607-3p;hsa-miR-374a-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-542-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 24 PIK3R1 Sponge network -4.222 0 -1.285 0 0.438
13

AC007743.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-374a-3p;hsa-miR-424-5p;hsa-miR-429;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 21 PIK3R1 Sponge network -2.595 0 -1.285 0 0.436
14

RP11-815I9.4

 hsa-miR-106a-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-3607-3p;hsa-miR-590-5p 12 PIK3R1 Sponge network -0.881 0.0002 -1.285 0 0.43
15

AF131215.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-3607-3p;hsa-miR-542-3p;hsa-miR-589-3p 15 PIK3R1 Sponge network -2.09 0 -1.285 0 0.428
16

RP11-456K23.1

 hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-224-5p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-450b-5p;hsa-miR-542-3p;hsa-miR-590-3p;hsa-miR-590-5p 12 BCL2 Sponge network -1.488 0 -0.487 0.06421 0.423
17

RP11-1024P17.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-429;hsa-miR-582-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p 22 PIK3R1 Sponge network -2.062 0 -1.285 0 0.418
18

RP11-400K9.4

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29b-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -1.193 0.00359 -1.285 0 0.418
19

RP11-672A2.4

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-22-5p;hsa-miR-424-5p 13 PIK3R1 Sponge network -2.68 0 -1.285 0 0.417
20

RP11-456K23.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-542-3p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 25 PIK3R1 Sponge network -1.488 0 -1.285 0 0.416
21

RP11-354E11.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-96-5p 19 PIK3R1 Sponge network -2.138 0 -1.285 0 0.41
22

RP11-401P9.4

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-374a-3p;hsa-miR-542-3p;hsa-miR-590-5p;hsa-miR-93-5p 17 PIK3R1 Sponge network -3.04 0 -1.285 0 0.408
23

LIPE-AS1

 hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-10a-3p;hsa-miR-148a-3p;hsa-miR-155-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-582-5p;hsa-miR-590-5p;hsa-miR-766-3p 15 PRKAR2A Sponge network -0.734 0.00039 -0.542 0.00821 0.408
24

CTD-2013N24.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-3607-3p;hsa-miR-374a-3p;hsa-miR-424-5p;hsa-miR-429;hsa-miR-582-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 28 PIK3R1 Sponge network -1.745 0 -1.285 0 0.407
25 CTD-2353F22.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p 10 PIK3R1 Sponge network -1.501 0.00083 -1.285 0 0.407
26

GAS6-AS2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-28-3p;hsa-miR-335-3p 11 AKT3 Sponge network -1.761 0 -1.44 0 0.397
27

RP11-532F6.3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-590-3p;hsa-miR-629-3p 16 PIK3R1 Sponge network -2.028 0 -1.285 0 0.395
28

MIR497HG

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 24 PIK3R1 Sponge network -2.142 0 -1.285 0 0.391
29

RP11-456K23.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-146b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-22-3p;hsa-miR-28-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-424-5p;hsa-miR-542-3p;hsa-miR-93-5p 17 AKT3 Sponge network -1.488 0 -1.44 0 0.389
30

TBX5-AS1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-28-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-542-3p 14 AKT3 Sponge network -2.108 0 -1.44 0 0.386
31

MAGI2-AS3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-93-5p 13 AKT3 Sponge network -1.892 0 -1.44 0 0.386
32

RP11-399O19.9

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-429;hsa-miR-93-5p 14 PIK3R1 Sponge network -0.873 0.00072 -1.285 0 0.38
33

FGF14-AS2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-96-5p 13 PIK3R1 Sponge network -2.159 0 -1.285 0 0.378
34

HHIP-AS1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-590-3p 16 PIK3R1 Sponge network -2.807 0 -1.285 0 0.374
35 LINC00092 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-542-3p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p 15 PIK3R1 Sponge network -2.383 0 -1.285 0 0.369
36

RP11-378A13.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 18 PIK3R1 Sponge network -1.713 0 -1.285 0 0.367
37

RP11-462G12.2

 hsa-miR-130b-3p;hsa-miR-192-5p;hsa-miR-193a-3p;hsa-miR-193b-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-26b-3p;hsa-miR-330-5p;hsa-miR-590-3p 10 ENDOD1 Sponge network -0.602 0.22954 0.057 0.80229 0.366
38

CTD-2013N24.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-181b-5p;hsa-miR-20a-5p;hsa-miR-22-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-424-5p;hsa-miR-93-5p 16 AKT3 Sponge network -1.745 0 -1.44 0 0.366
39

SH3RF3-AS1

 hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-582-5p;hsa-miR-590-5p 15 PIK3R1 Sponge network -1.583 0 -1.285 0 0.364
40

AC011899.9

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-590-3p 16 PIK3R1 Sponge network -2.611 0 -1.285 0 0.364
41

AC079630.4

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-3607-3p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-93-5p 15 PIK3R1 Sponge network -3.758 0 -1.285 0 0.359
42

RP5-1042I8.7

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 17 PIK3R1 Sponge network -0.733 0.00018 -1.285 0 0.358
43

AC003090.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 17 PIK3R1 Sponge network -3.16 2.0E-5 -1.285 0 0.358
44

GAS6-AS2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-429;hsa-miR-450b-5p;hsa-miR-590-5p 20 PIK3R1 Sponge network -1.761 0 -1.285 0 0.354
45

RP11-815I9.4

 hsa-miR-106a-5p;hsa-miR-142-3p;hsa-miR-146b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29b-3p 10 AKT3 Sponge network -0.881 0.0002 -1.44 0 0.35
46

MAGI2-AS3

 hsa-miR-141-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-324-5p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-429;hsa-miR-501-5p;hsa-miR-589-3p;hsa-miR-660-5p 12 IRAK3 Sponge network -1.892 0 -1.317 1.0E-5 0.348
47

LINC00961

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-96-5p 17 PIK3R1 Sponge network -2.724 0 -1.285 0 0.346
48

RBMS3-AS3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-22-5p;hsa-miR-629-3p;hsa-miR-96-5p 12 PIK3R1 Sponge network -2.307 0.0011 -1.285 0 0.345
49 AC010226.4 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -1.081 2.0E-5 -1.285 0 0.344
50

AC003991.3

 hsa-miR-130a-3p;hsa-miR-130b-3p;hsa-miR-16-1-3p;hsa-miR-192-5p;hsa-miR-193a-3p;hsa-miR-193b-3p;hsa-miR-19a-3p;hsa-miR-20a-3p;hsa-miR-26b-3p;hsa-miR-301a-3p;hsa-miR-335-3p;hsa-miR-590-3p 12 ENDOD1 Sponge network -0.787 0.08132 0.057 0.80229 0.343
51

LINC00987

 hsa-miR-106a-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-93-5p;hsa-miR-96-5p 14 PIK3R1 Sponge network -0.927 0 -1.285 0 0.343
52 BZRAP1-AS1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -0.785 0.00723 -1.285 0 0.34
53

RP11-5C23.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-3607-3p;hsa-miR-582-5p;hsa-miR-590-3p 14 PIK3R1 Sponge network -0.758 0.00105 -1.285 0 0.339
54

AC011526.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-374a-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p 15 PIK3R1 Sponge network -2.783 0 -1.285 0 0.338
55

AC004947.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 17 PIK3R1 Sponge network -3.94 0 -1.285 0 0.332
56 CTC-523E23.4 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-590-3p 11 PIK3R1 Sponge network -1.636 0.00051 -1.285 0 0.33
57

WDFY3-AS2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-3607-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-96-5p 21 PIK3R1 Sponge network -1.297 0 -1.285 0 0.329
58

CTD-2003C8.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-590-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -3.403 0 -1.285 0 0.328
59

LINC00883

 hsa-miR-107;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-629-3p 13 PIK3R1 Sponge network -1.466 0 -1.285 0 0.327
60 CTC-429P9.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -0.908 0.00061 -1.285 0 0.326
61

RP11-389C8.2

 hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-24-2-5p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-542-3p;hsa-miR-590-3p 10 BCL2 Sponge network -2.039 0 -0.487 0.06421 0.325
62

RP11-389C8.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-28-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-542-3p;hsa-miR-93-5p 12 AKT3 Sponge network -2.039 0 -1.44 0 0.324
63

RP11-401P9.4

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-146b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-542-3p;hsa-miR-93-5p 11 AKT3 Sponge network -3.04 0 -1.44 0 0.323
64

AC020571.3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-29b-2-5p;hsa-miR-3065-5p;hsa-miR-335-3p;hsa-miR-362-5p 10 AKT3 Sponge network 0.248 0.40984 -1.44 0 0.321
65

RP11-293M10.6

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-590-5p;hsa-miR-93-5p 11 PIK3R1 Sponge network -1.199 0.00063 -1.285 0 0.32
66

RP11-354E11.2

 hsa-miR-130b-3p;hsa-miR-16-1-3p;hsa-miR-192-5p;hsa-miR-193a-3p;hsa-miR-193b-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-26b-3p;hsa-miR-301a-3p;hsa-miR-330-5p;hsa-miR-335-3p;hsa-miR-590-3p 13 ENDOD1 Sponge network -2.138 0 0.057 0.80229 0.32
67 RP11-434D9.1 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-590-3p;hsa-miR-629-3p 11 PIK3R1 Sponge network -4.573 0 -1.285 0 0.319
68

NR2F1-AS1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 20 PIK3R1 Sponge network -0.427 0.1559 -1.285 0 0.318
69

CTC-559E9.4

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-590-5p;hsa-miR-93-5p 12 PIK3R1 Sponge network -0.737 0.0562 -1.285 0 0.318
70

RP11-789C1.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-93-5p 12 PIK3R1 Sponge network -4.664 0.00012 -1.285 0 0.317
71

LINC00607

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-429;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p 18 PIK3R1 Sponge network -2.277 0 -1.285 0 0.316
72 RP11-517P14.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-590-3p;hsa-miR-93-5p 11 PIK3R1 Sponge network -0.795 6.0E-5 -1.285 0 0.315
73

RP4-639F20.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-96-5p 13 PIK3R1 Sponge network -1.312 0 -1.285 0 0.314
74

RP11-1223D19.1

 hsa-miR-130a-3p;hsa-miR-130b-3p;hsa-miR-192-5p;hsa-miR-193a-3p;hsa-miR-193b-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-3613-5p;hsa-miR-590-3p 11 ENDOD1 Sponge network -0.862 0.05389 0.057 0.80229 0.314
75 RP1-151F17.2 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-582-5p;hsa-miR-590-5p 10 PIK3R1 Sponge network -0.793 0.00074 -1.285 0 0.313
76 RP11-736K20.5 hsa-miR-15a-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p 10 PIK3R1 Sponge network -1.84 0 -1.285 0 0.312
77

FZD10-AS1

 hsa-miR-146b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-28-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-424-5p;hsa-miR-542-3p 10 AKT3 Sponge network -1.071 0.02419 -1.44 0 0.309
78

CTD-2619J13.17

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-320b;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -0.819 0.00282 -1.285 0 0.307
79

LINC00968

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-28-3p;hsa-miR-424-5p;hsa-miR-93-5p 12 AKT3 Sponge network -4.19 0 -1.44 0 0.305
80

RP11-244O19.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -0.428 0.21699 -1.285 0 0.303
81

RP11-462G12.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-93-5p 16 PIK3R1 Sponge network -1.071 0.01175 -1.285 0 0.302
82 LINC01088 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -1.385 0.01604 -1.285 0 0.3
83

CTD-2269F5.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-93-5p 10 AKT3 Sponge network -1.576 0.00334 -1.44 0 0.3
84 AC016735.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-582-5p;hsa-miR-96-5p 12 PIK3R1 Sponge network -2.711 0.00282 -1.285 0 0.298
85

RP11-67L2.2

 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-3607-3p;hsa-miR-374a-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p 14 PIK3R1 Sponge network -1.062 0 -1.285 0 0.298
86

TBX5-AS1

 hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-24-2-5p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-33a-5p;hsa-miR-365a-3p;hsa-miR-450b-5p;hsa-miR-542-3p;hsa-miR-590-5p 14 BCL2 Sponge network -2.108 0 -0.487 0.06421 0.297
87

LINC00702

 hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-33a-5p;hsa-miR-34a-5p;hsa-miR-450b-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-96-5p 14 BCL2 Sponge network -2.856 0 -0.487 0.06421 0.297
88

RP11-88I21.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-429;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 14 PIK3R1 Sponge network -8.789 0 -1.285 0 0.297
89

RP11-1008C21.2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-3607-3p;hsa-miR-629-3p;hsa-miR-93-5p 18 PIK3R1 Sponge network -1.249 0 -1.285 0 0.297
90 AC034187.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -1.974 0 -1.285 0 0.297
91

AC109642.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-29b-3p;hsa-miR-424-5p;hsa-miR-93-5p 12 AKT3 Sponge network -2.791 0 -1.44 0 0.293
92 RP11-365O16.3 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-93-5p 13 PIK3R1 Sponge network -2.765 0.00017 -1.285 0 0.293
93

FENDRR

 hsa-miR-141-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-3200-3p;hsa-miR-324-5p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-450b-5p 10 IRAK3 Sponge network -4.222 0 -1.317 1.0E-5 0.291
94

CASC2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-3607-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 21 PIK3R1 Sponge network -1.086 0 -1.285 0 0.29
95

RP11-532F6.3

 hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-24-2-5p;hsa-miR-29a-5p;hsa-miR-33a-5p;hsa-miR-590-3p 10 BCL2 Sponge network -2.028 0 -0.487 0.06421 0.29
96

RP11-686D22.8

 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p 10 PIK3R1 Sponge network -0.161 0.52228 -1.285 0 0.29
97

RP11-416I2.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-3p;hsa-miR-93-5p 10 PPP3CA Sponge network 3.177 1.0E-5 -0.314 0.01652 0.289
98

LINC00702

 hsa-miR-141-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-450b-5p;hsa-miR-501-5p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-660-5p 12 IRAK3 Sponge network -2.856 0 -1.317 1.0E-5 0.285
99 RP11-268F1.3 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-22-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-96-5p 10 PIK3R1 Sponge network -6.474 1.0E-5 -1.285 0 0.285
100

RP11-284N8.3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 20 PIK3R1 Sponge network -0.761 0.05061 -1.285 0 0.285
101 AF131215.9 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-590-3p 12 PIK3R1 Sponge network -1.808 0 -1.285 0 0.282
102

WDFY3-AS2

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-142-5p;hsa-miR-17-5p;hsa-miR-194-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-3607-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-642a-5p;hsa-miR-7-1-3p;hsa-miR-96-5p 18 PPP3CA Sponge network -1.297 0 -0.314 0.01652 0.281
103

RP11-352D13.6

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-424-5p;hsa-miR-542-3p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 17 PIK3R1 Sponge network -4.634 0 -1.285 0 0.28
104

LIPE-AS1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-424-5p;hsa-miR-582-5p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 21 PIK3R1 Sponge network -0.734 0.00039 -1.285 0 0.28
105 SRGAP3-AS2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-450b-5p 10 PIK3R1 Sponge network -5.086 5.0E-5 -1.285 0 0.279
106

RP11-401P9.4

 hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-224-5p;hsa-miR-29a-5p;hsa-miR-33a-5p;hsa-miR-542-3p;hsa-miR-590-5p 10 BCL2 Sponge network -3.04 0 -0.487 0.06421 0.279
107

RP11-476D10.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-96-5p 14 PIK3R1 Sponge network -4.519 0 -1.285 0 0.279
108

BDNF-AS

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 16 PIK3R1 Sponge network -0.568 0.02011 -1.285 0 0.277
109 CTD-2135D7.5 hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-590-5p;hsa-miR-629-3p 11 PIK3R1 Sponge network -3.162 0 -1.285 0 0.277
110 CTC-441N14.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-582-5p;hsa-miR-96-5p 13 PIK3R1 Sponge network -2.273 0.01231 -1.285 0 0.276
111

AC011526.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-424-5p;hsa-miR-93-5p 10 AKT3 Sponge network -2.783 0 -1.44 0 0.276
112

LINC00443

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-542-3p 15 PIK3R1 Sponge network -3.704 0.0003 -1.285 0 0.276
113

AC008268.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-629-3p;hsa-miR-93-5p 11 PIK3R1 Sponge network -5.661 0 -1.285 0 0.276
114

LIPE-AS1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-582-5p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-642a-5p;hsa-miR-93-3p;hsa-miR-93-5p;hsa-miR-96-5p 17 PPP3CA Sponge network -0.734 0.00039 -0.314 0.01652 0.274
115

RP11-1008C21.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-320b;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-629-3p 15 PIK3R1 Sponge network -1.826 3.0E-5 -1.285 0 0.272
116

SNHG18

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -1.073 0.00533 -1.285 0 0.27
117 C1orf132 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-374a-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-542-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 15 PIK3R1 Sponge network -0.86 0.02429 -1.285 0 0.269
118 LINC00551 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-629-3p;hsa-miR-96-5p 10 PIK3R1 Sponge network -2.179 0.00466 -1.285 0 0.269
119

CTD-2013N24.2

 hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-33a-5p;hsa-miR-590-3p 10 BCL2 Sponge network -1.745 0 -0.487 0.06421 0.268
120 RP11-890B15.3 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-335-3p;hsa-miR-374a-3p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p 11 PIK3R1 Sponge network -0.389 0.02728 -1.285 0 0.268
121

TBX5-AS1

 hsa-miR-141-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-3200-3p;hsa-miR-324-5p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-450b-5p;hsa-miR-501-5p;hsa-miR-590-5p 12 IRAK3 Sponge network -2.108 0 -1.317 1.0E-5 0.267
122

LINC00657

 hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-142-5p;hsa-miR-155-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-29a-5p;hsa-miR-342-5p;hsa-miR-766-3p 10 PRKAR2A Sponge network -0.222 0.34002 -0.542 0.00821 0.266
123

LINC01024

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-3607-3p;hsa-miR-590-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -0.659 0.02711 -1.285 0 0.266
124 CTC-366B18.4 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-374a-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -0.652 0.01265 -1.285 0 0.265
125

LINC00472

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-22-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-93-5p 11 AKT3 Sponge network -2.952 0 -1.44 0 0.265
126

NR2F1-AS1

 hsa-miR-106a-5p;hsa-miR-129-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-192-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-215-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-582-5p;hsa-miR-7-1-3p;hsa-miR-93-5p 14 IL1RAP Sponge network -0.427 0.1559 0 0.99919 0.265
127

LINC00511

 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-139-5p;hsa-miR-195-3p;hsa-miR-30a-5p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-362-3p;hsa-miR-374a-5p 10 CASP3 Sponge network 2.848 0 0.75 0 0.264
128

RP1-78O14.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-629-3p 12 PIK3R1 Sponge network -4.409 0 -1.285 0 0.264
129

AC096670.3

 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-3607-3p;hsa-miR-424-5p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -1.939 7.0E-5 -1.285 0 0.263
130

AC007743.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-5p;hsa-miR-148a-3p;hsa-miR-155-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-590-5p 13 PRKAR2A Sponge network -2.595 0 -0.542 0.00821 0.263
131

RP11-815I9.4

 hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-24-2-5p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-34a-5p;hsa-miR-590-5p 10 BCL2 Sponge network -0.881 0.0002 -0.487 0.06421 0.262
132

RP5-839B4.8

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-629-3p;hsa-miR-93-5p 16 PIK3R1 Sponge network -5.037 0 -1.285 0 0.262
133

MIR497HG

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-424-5p;hsa-miR-93-5p 11 AKT3 Sponge network -2.142 0 -1.44 0 0.262
134 DIO3OS hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-424-5p;hsa-miR-542-3p;hsa-miR-589-3p;hsa-miR-629-3p 15 PIK3R1 Sponge network -1.936 0.00085 -1.285 0 0.262
135 CTC-523E23.1 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-590-3p;hsa-miR-629-3p 10 PIK3R1 Sponge network -1.223 0.0005 -1.285 0 0.262
136 RP4-668J24.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-629-3p 12 PIK3R1 Sponge network -2.397 0.00331 -1.285 0 0.261
137 RP11-347J14.7 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-96-5p 11 PIK3R1 Sponge network -5.394 0 -1.285 0 0.261
138 RP11-582J16.4 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-21-5p;hsa-miR-3607-3p;hsa-miR-374a-3p;hsa-miR-424-5p;hsa-miR-542-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-96-5p 12 PIK3R1 Sponge network -2.665 0.00014 -1.285 0 0.26
139

LINC00261

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p 18 PIK3R1 Sponge network -2.566 0.00025 -1.285 0 0.259
140 RP11-23P13.6 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-320b;hsa-miR-590-3p;hsa-miR-629-3p 12 PIK3R1 Sponge network -0.705 0.00072 -1.285 0 0.256
141

GAS6-AS2

 hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-33a-5p;hsa-miR-450b-5p;hsa-miR-590-5p 10 BCL2 Sponge network -1.761 0 -0.487 0.06421 0.256
142 AGAP11 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-21-5p;hsa-miR-320b;hsa-miR-3607-3p;hsa-miR-424-5p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -2.127 0 -1.285 0 0.255
143 LINC00619 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p 12 PIK3R1 Sponge network -2.307 0.02217 -1.285 0 0.255
144

DNM3OS

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-320b;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 19 PIK3R1 Sponge network 0.053 0.85755 -1.285 0 0.255
145

CTA-221G9.11

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -0.645 0.06404 -1.285 0 0.254
146

PCED1B-AS1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-429;hsa-miR-93-5p;hsa-miR-96-5p 13 PIK3R1 Sponge network -0.672 0.02084 -1.285 0 0.254
147

RP11-1024P17.1

 hsa-miR-141-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-3200-3p;hsa-miR-324-5p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-429;hsa-miR-589-3p 10 IRAK3 Sponge network -2.062 0 -1.317 1.0E-5 0.254
148

RP11-473I1.9

 hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-29a-5p;hsa-miR-335-3p;hsa-miR-501-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-3p;hsa-miR-93-5p 10 PPP3CA Sponge network -0.037 0.8641 -0.314 0.01652 0.252
149 RP11-677M14.3 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-20b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 11 PIK3R1 Sponge network -1.866 0 -1.285 0 0.251
150

MIR497HG

 hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-450b-5p;hsa-miR-590-5p;hsa-miR-96-5p 10 BCL2 Sponge network -2.142 0 -0.487 0.06421 0.251
151 AC012501.2 hsa-miR-139-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-30a-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-342-3p 10 PPP3R1 Sponge network 2.091 0.06305 -0.021 0.82881 0.251

Quest ID: 07cdafe05b23dc98502e9204740c0c2e