Visible node/edge number:
Node colors:
Node labels:

show label of nodes with degree >=

Node sizes:
Edge colors:
Edge widths factor:
Layout:

gravity >=

edgeLength =

GRN in network:

Notice: IE browser need to manually refresh (F5) this page after resetting the network.

This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-335-3p BMP2 2.52 0 -0.33 0.46013 mirMAP -0.23 0.00128 NA
2 hsa-miR-338-3p BMP7 -0.96 0.01915 0.77 0.31178 miRanda -0.54 3.0E-5 NA
3 hsa-miR-3614-3p BMP7 0.82 0.01436 0.77 0.31178 mirMAP -0.56 0.00079 NA
4 hsa-miR-362-3p BMP7 -0.03 0.91378 0.77 0.31178 miRanda -0.47 0.00508 NA
5 hsa-miR-134-5p EPB41L5 0.57 0.10962 -0.5 0.02395 MirTarget -0.14 0.00137 NA
6 hsa-miR-152-3p EPB41L5 0.44 0.1617 -0.5 0.02395 MirTarget -0.28 0 NA
7 hsa-miR-16-2-3p EPB41L5 1.8 0 -0.5 0.02395 mirMAP -0.14 0.00569 NA
8 hsa-miR-224-3p EPB41L5 1.52 0.0065 -0.5 0.02395 mirMAP -0.14 0 NA
9 hsa-miR-328-3p EPB41L5 -0.38 0.16088 -0.5 0.02395 MirTarget -0.17 0.00342 NA
10 hsa-miR-33a-5p EPB41L5 0.41 0.32143 -0.5 0.02395 mirMAP -0.15 0.0001 NA
11 hsa-miR-34c-3p EPB41L5 2.25 9.0E-5 -0.5 0.02395 mirMAP -0.15 0 NA
12 hsa-miR-142-3p FAM83D 1.32 0.00015 0.57 0.08496 miRanda -0.21 0.00194 NA
13 hsa-miR-192-5p FAM83D 0.08 0.94106 0.57 0.08496 miRNAWalker2 validate -0.14 0 NA
14 hsa-miR-19b-3p FAM83D 0.76 0.00653 0.57 0.08496 miRNATAP -0.27 0.00112 NA
15 hsa-miR-429 FAM83D 1.4 0.009 0.57 0.08496 miRanda -0.17 6.0E-5 NA
16 hsa-miR-186-5p FGFR2 0.15 0.43471 -0.1 0.81404 miRNAWalker2 validate -0.42 0.00939 NA
17 hsa-miR-326 FGFR2 -0.43 0.26299 -0.1 0.81404 miRanda -0.23 0.00385 NA
18 hsa-miR-338-3p FGFR2 -0.96 0.01915 -0.1 0.81404 miRanda; miRNATAP -0.2 0.00698 NA
19 hsa-miR-130b-3p FOXF2 1.33 5.0E-5 -0.83 0.02659 miRNATAP -0.35 1.0E-5 NA
20 hsa-miR-142-3p FOXF2 1.32 0.00015 -0.83 0.02659 miRanda -0.37 0 NA
21 hsa-miR-182-5p FOXF2 0.89 0.03106 -0.83 0.02659 miRNAWalker2 validate; miRNATAP -0.23 0.00042 25738520 miR 182 promotes cell growth and invasion by targeting forkhead box F2 transcription factor in colorectal cancer; In the present study we aimed to investigate the role of miR-182 in colorectal cancer CRC and identify the regulation of FoxF2 by miR-182; The direct binding of miR-182 to the 3' untranslated region 3'UTR of FoxF2 mRNA was confirmed using a luciferase reporter gene assay
22 hsa-miR-19a-3p FOXF2 1.27 0.00011 -0.83 0.02659 miRNATAP -0.49 0 NA
23 hsa-miR-19b-3p FOXF2 0.76 0.00653 -0.83 0.02659 miRNATAP -0.62 0 NA
24 hsa-miR-200b-3p FOXF2 0.97 0.0595 -0.83 0.02659 TargetScan -0.26 0 25798833 The miR 200 family and the miR 183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers; We therefore identified a novel mechanism whereby the miR-200 family and the miR-183~96~182 cluster inhibit lung cancer invasion and metastasis by targeting Foxf2
25 hsa-miR-200c-3p FOXF2 1.28 0.0037 -0.83 0.02659 miRNATAP -0.32 0 NA
26 hsa-miR-26b-5p FOXF2 -0.3 0.16008 -0.83 0.02659 miRNAWalker2 validate -0.46 0.00032 NA
27 hsa-miR-3607-3p FOXF2 0.52 0.08425 -0.83 0.02659 miRNATAP -0.36 4.0E-5 NA
28 hsa-miR-3662 FOXF2 1.83 0.0054 -0.83 0.02659 mirMAP -0.2 0.00015 NA
29 hsa-miR-429 FOXF2 1.4 0.009 -0.83 0.02659 PITA; miRanda; miRNATAP -0.26 0 NA
30 hsa-miR-454-3p FOXF2 0.63 0.01349 -0.83 0.02659 miRNATAP -0.3 0.00485 NA
31 hsa-miR-590-3p FOXF2 1.12 0.00016 -0.83 0.02659 PITA; miRanda -0.43 0 NA
32 hsa-miR-96-5p FOXF2 1.14 0.00943 -0.83 0.02659 TargetScan; miRNATAP -0.24 0.00017 NA
33 hsa-miR-101-3p GSK3B -0.45 0.02834 0.17 0.35876 miRNATAP -0.31 0 NA
34 hsa-miR-212-3p GSK3B 0.96 0.00133 0.17 0.35876 mirMAP; miRNATAP -0.16 0.00037 NA
35 hsa-miR-26a-5p GSK3B -0.38 0.04425 0.17 0.35876 miRNAWalker2 validate; miRNATAP -0.3 3.0E-5 NA
36 hsa-miR-26b-5p GSK3B -0.3 0.16008 0.17 0.35876 miRNATAP -0.2 0.00136 NA
37 hsa-miR-29a-3p GSK3B -0.11 0.61501 0.17 0.35876 miRNATAP -0.24 7.0E-5 NA
38 hsa-miR-29b-3p GSK3B -0.23 0.36746 0.17 0.35876 miRTarBase; miRNATAP -0.14 0.00818 NA
39 hsa-miR-29c-3p GSK3B -1.62 0 0.17 0.35876 miRNATAP -0.15 0.00019 NA
40 hsa-miR-30d-3p GSK3B -0.55 0.04337 0.17 0.35876 miRNATAP -0.13 0.00688 NA
41 hsa-miR-340-5p GSK3B -0.16 0.52991 0.17 0.35876 mirMAP -0.18 0.0003 NA
42 hsa-let-7a-3p HGF 0.5 0.04111 -0.38 0.55049 mirMAP -0.82 1.0E-5 NA
43 hsa-let-7b-3p HGF 0.22 0.29604 -0.38 0.55049 mirMAP -0.85 9.0E-5 NA
44 hsa-miR-141-3p HGF 1.46 0.00116 -0.38 0.55049 MirTarget; TargetScan -0.49 0 NA
45 hsa-miR-203a-3p HGF 1.45 0.03941 -0.38 0.55049 MirTarget -0.52 0 NA
46 hsa-miR-224-3p HGF 1.52 0.0065 -0.38 0.55049 mirMAP -0.46 0 NA
47 hsa-miR-33a-3p HGF 0.35 0.32171 -0.38 0.55049 mirMAP -0.54 5.0E-5 NA
48 hsa-miR-34c-5p HGF 2.21 0.00038 -0.38 0.55049 miRanda -0.31 2.0E-5 NA
49 hsa-miR-3682-3p HGF 1.97 0 -0.38 0.55049 mirMAP -0.4 0.00077 NA
50 hsa-miR-590-5p HGF 1.04 0.00027 -0.38 0.55049 miRanda -0.58 0.00019 NA
51 hsa-miR-944 HGF 3.33 0.01778 -0.38 0.55049 mirMAP -0.25 0 NA
52 hsa-miR-106b-5p HIF1A 1.71 0 0.84 0.00084 MirTarget -0.17 0.00333 NA
53 hsa-miR-107 HIF1A 0.9 5.0E-5 0.84 0.00084 miRNAWalker2 validate; miRTarBase; miRanda -0.36 1.0E-5 NA
54 hsa-miR-139-5p HIF1A -1.83 0 0.84 0.00084 miRanda -0.16 0.00469 NA
55 hsa-miR-151a-3p HIF1A 1 1.0E-5 0.84 0.00084 MirTarget -0.23 0.00333 NA
56 hsa-miR-320c HIF1A 0.46 0.24061 0.84 0.00084 miRanda -0.15 0.00656 NA
57 hsa-miR-330-3p HIF1A 0.8 0.00747 0.84 0.00084 MirTarget; PITA -0.18 0.00313 NA
58 hsa-miR-338-3p HIF1A -0.96 0.01915 0.84 0.00084 MirTarget; PITA; miRanda -0.18 3.0E-5 NA
59 hsa-miR-338-5p HIF1A -1.2 0.01003 0.84 0.00084 MirTarget; PITA; miRNATAP -0.14 0.0002 NA
60 hsa-miR-361-5p HIF1A 0.41 0.01813 0.84 0.00084 miRanda -0.31 0.00432 NA
61 hsa-miR-660-5p HIF1A -0.02 0.93887 0.84 0.00084 MirTarget -0.28 2.0E-5 NA
62 hsa-miR-129-5p HMGA2 -2.57 0 3.29 1.0E-5 miRanda; mirMAP -0.4 7.0E-5 NA
63 hsa-miR-195-3p HMGA2 -1.35 2.0E-5 3.29 1.0E-5 mirMAP -0.48 0.00544 NA
64 hsa-miR-195-5p HMGA2 -0.91 0.00151 3.29 1.0E-5 MirTarget -0.57 0.00284 NA
65 hsa-miR-23b-3p HMGA2 -0.29 0.18665 3.29 1.0E-5 mirMAP -0.7 0.00716 NA
66 hsa-miR-29b-2-5p HMGA2 -1.7 0 3.29 1.0E-5 mirMAP -1.01 0 NA
67 hsa-miR-30d-5p HMGA2 -0.55 0.01401 3.29 1.0E-5 mirMAP -0.91 0.00027 NA
68 hsa-miR-30e-3p HMGA2 -0.91 1.0E-5 3.29 1.0E-5 MirTarget -0.88 0.00106 NA
69 hsa-miR-664a-3p HMGA2 -0.83 0.00014 3.29 1.0E-5 mirMAP -1.08 2.0E-5 NA
70 hsa-miR-664a-5p HMGA2 -0.13 0.62435 3.29 1.0E-5 MirTarget -0.55 0.00812 NA
71 hsa-miR-29b-2-5p HNRNPAB -1.7 0 0.59 0.0003 MirTarget -0.13 0.00126 NA
72 hsa-miR-7-1-3p LEF1 0.71 0.04123 1.62 5.0E-5 mirMAP -0.22 0.0094 NA
73 hsa-miR-221-3p LIMS1 1.33 0 0.06 0.73539 miRNAWalker2 validate; MirTarget -0.14 0.00327 NA
74 hsa-miR-222-3p LIMS1 1.39 0 0.06 0.73539 MirTarget -0.12 0.0087 NA
75 hsa-miR-30b-5p LIMS1 -0.43 0.05936 0.06 0.73539 MirTarget -0.19 0.0008 NA
76 hsa-miR-30d-5p LIMS1 -0.55 0.01401 0.06 0.73539 MirTarget -0.17 0.00243 NA
77 hsa-miR-590-3p LIMS1 1.12 0.00016 0.06 0.73539 miRNAWalker2 validate; miRanda -0.12 0.00533 NA
78 hsa-miR-126-5p NOG 0.42 0.07532 -1.03 0.09157 mirMAP; miRNATAP -0.76 5.0E-5 NA
79 hsa-miR-144-3p NOG -0.13 0.79825 -1.03 0.09157 miRNATAP -0.26 0.00181 NA
80 hsa-miR-148b-3p NOG 0.3 0.17466 -1.03 0.09157 MirTarget -0.63 0.00197 NA
81 hsa-miR-200b-3p NOG 0.97 0.0595 -1.03 0.09157 MirTarget; TargetScan -0.54 0 NA
82 hsa-miR-200c-3p NOG 1.28 0.0037 -1.03 0.09157 MirTarget; miRNATAP -0.53 0 NA
83 hsa-miR-338-5p NOG -1.2 0.01003 -1.03 0.09157 miRNATAP -0.26 0.00475 NA
84 hsa-miR-362-3p NOG -0.03 0.91378 -1.03 0.09157 miRanda; miRNATAP -0.46 0.00075 NA
85 hsa-miR-375 NOG -2.95 0.0057 -1.03 0.09157 miRanda -0.21 0 NA
86 hsa-miR-429 NOG 1.4 0.009 -1.03 0.09157 MirTarget; PITA; miRanda; miRNATAP -0.45 0 NA
87 hsa-miR-101-3p NOTCH1 -0.45 0.02834 1.03 0.00018 MirTarget -0.41 3.0E-5 NA
88 hsa-miR-139-5p NOTCH1 -1.83 0 1.03 0.00018 PITA; miRanda; miRNATAP -0.24 0.0001 27173050; 25149074; 26299922; 27738333; 24885920 miR 139 5p sensitizes colorectal cancer cells to 5 fluorouracil by targeting NOTCH 1;MiR 139 5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1; Mechanistic investigations revealed that miR-139-5p suppress CRC cell invasion and metastasis by targeting AMFR and NOTCH1;MiR 139 5p inhibits the biological function of breast cancer cells by targeting Notch1 and mediates chemosensitivity to docetaxel; MiR-139-5p expression in MCF-7 MCF-7/Doc cells and in selected breast cancer tissue samples was confirmed by real-time PCR; cell viability was analyzed by Cell Counting Kit-8 assay; apoptosis and cell cycle were analyzed by flow cytometry; control of metastasis and invasion of breast cancer cells was measured by transwell assay; expression of Notch1 was measured by western blot; a luciferase reporter vector was constructed to identify the miR-139-5p target gene; MiR-139-5p not only attenuated the development of breast cancer cells but also mediated drug-resistance by regulating the expression of the downstream target gene Notch1;MiR 139 5p reverses CD44+/CD133+ associated multidrug resistance by downregulating NOTCH1 in colorectal carcinoma cells; We also identified NOTCH1 an important protein for stem cell maintenance and function as a direct target of miR-139-5p both in vitro and in a knockout mouse model; Notch1 expression was upregulated in tumor samples and inversely correlated with expression of miR-139-5p; Silencing NOTCH1 exerted an effect similar to overexpression of miR-139-5p by inhibiting the CD44+ and CD133+ population and reversing the drug-resistant phenotype; In conclusion miR-139-5p downregulated NOTCH1 signaling to reverse CD44+/CD133+-associated MDR in colorectal cancer cells;microRNA 139 5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer
89 hsa-miR-30a-5p NOTCH1 -1.72 0 1.03 0.00018 miRNAWalker2 validate; miRTarBase; miRNATAP -0.24 3.0E-5 NA
90 hsa-miR-30b-5p NOTCH1 -0.43 0.05936 1.03 0.00018 miRNATAP -0.36 4.0E-5 NA
91 hsa-miR-30c-5p NOTCH1 -0.98 5.0E-5 1.03 0.00018 miRNATAP -0.33 6.0E-5 23974200 We identified NOTCH1 as a direct target of miR-30c; Finally a block of miR-30c prevents C/EBPα-induced downregulation of Notch1 protein and leads to a reduced CD11b expression in myeloid differentiation; Our study presents the first evidence that C/EBPα miR-30c and Notch1 together play a critical role in granulocytic differentiation and AML and particularly in AML with CEBPA mutations
92 hsa-miR-30d-5p NOTCH1 -0.55 0.01401 1.03 0.00018 miRNATAP -0.28 0.00181 NA
93 hsa-miR-32-5p NOTCH1 0.42 0.10646 1.03 0.00018 miRNATAP -0.25 0.00133 NA
94 hsa-miR-326 NOTCH1 -0.43 0.26299 1.03 0.00018 miRNAWalker2 validate; miRTarBase -0.17 0.00149 NA
95 hsa-miR-151a-3p RBPJ 1 1.0E-5 -0.39 0.00735 miRNATAP -0.12 0.00733 NA
96 hsa-miR-15b-5p RBPJ 1.62 0 -0.39 0.00735 MirTarget -0.12 0.00077 NA
97 hsa-miR-200c-3p RBPJ 1.28 0.0037 -0.39 0.00735 mirMAP -0.11 0 NA
98 hsa-miR-107 SNAI2 0.9 5.0E-5 0.87 0.16367 miRanda -0.96 0 NA
99 hsa-miR-126-5p SNAI2 0.42 0.07532 0.87 0.16367 MirTarget -0.7 0.00024 NA
100 hsa-miR-140-5p SNAI2 0.21 0.303 0.87 0.16367 miRanda -0.71 0.00155 25322669; 27597739 Down regulation of miR 140 induces EMT and promotes invasion by targeting Slug in esophageal cancer; Slug a target gene of miR-140 was examined by luciferase assay and Western blot; miR-140 may regulate the cell invasion of EC via controlling Slug expression;Mechanistically Unigene56159 could directly bind to miR-140-5p and effectively act as a competing endogenous RNA ceRNA for miR-140-5p to de-repress the expression of the target gene Slug
101 hsa-miR-148b-3p SNAI2 0.3 0.17466 0.87 0.16367 miRNAWalker2 validate -0.88 2.0E-5 NA
102 hsa-miR-200b-3p SNAI2 0.97 0.0595 0.87 0.16367 TargetScan -0.48 0 NA
103 hsa-miR-335-3p SNAI2 2.52 0 0.87 0.16367 mirMAP -0.31 0.00223 NA
104 hsa-miR-3614-5p SNAI2 1.1 0.00706 0.87 0.16367 MirTarget -0.42 9.0E-5 NA
105 hsa-miR-375 SNAI2 -2.95 0.0057 0.87 0.16367 miRanda -0.41 0 NA
106 hsa-miR-429 SNAI2 1.4 0.009 0.87 0.16367 PITA; miRanda; miRNATAP -0.39 0 NA
107 hsa-miR-532-5p SNAI2 0.31 0.25225 0.87 0.16367 PITA -1.32 0 NA
108 hsa-miR-1-3p SOX9 -2.66 2.0E-5 1.26 0.00806 MirTarget -0.18 0.00086 NA
109 hsa-miR-129-5p SOX9 -2.57 0 1.26 0.00806 miRanda -0.24 7.0E-5 NA
110 hsa-miR-145-5p SOX9 -1.75 2.0E-5 1.26 0.00806 miRNATAP -0.37 1.0E-5 25145279; 24631504 The epigenetic regulation of SOX9 by miR 145 in human chondrosarcoma; We hypothesized that the expression of miR-145 is low in chondrosarcoma leading to decreased transcriptional control of SOX9 the master regulator of chondrogenesis and downstream activation of the transcription factor ETV5;Ectopic expression of miR-145 in turn regulates SOX9 expression through the binding to specific seed motifs; Together these results suggest that miR-145 is a novel target of PPARγ acts as a tumor suppressor in CRC cell lines and is a key regulator of intestinal cell differentiation by directly targeting SOX9 a marker of undifferentiated progenitors in the colonic crypts
111 hsa-miR-199a-5p SOX9 0.37 0.23266 1.26 0.00806 miRNAWalker2 validate -0.31 0.00435 NA
112 hsa-miR-9-3p SOX9 0.33 0.54111 1.26 0.00806 miRNATAP -0.35 0 NA
113 hsa-miR-139-5p TGFB1 -1.83 0 0.92 0.01544 miRanda -0.23 0.0078 NA
114 hsa-miR-29b-3p TGFB1 -0.23 0.36746 0.92 0.01544 miRTarBase -0.46 2.0E-5 NA
115 hsa-miR-141-3p TGFB2 1.46 0.00116 0.53 0.23727 miRNAWalker2 validate; miRTarBase; MirTarget; TargetScan; miRNATAP -0.31 1.0E-5 NA
116 hsa-miR-148a-3p TGFB2 -1.54 4.0E-5 0.53 0.23727 MirTarget; miRNATAP -0.22 0.00927 NA
117 hsa-miR-148b-3p TGFB2 0.3 0.17466 0.53 0.23727 MirTarget -0.47 0.00177 NA
118 hsa-miR-200a-3p TGFB2 0.72 0.19391 0.53 0.23727 MirTarget; miRNATAP -0.25 1.0E-5 25813153 Tumor suppressive microRNA 200a inhibits renal cell carcinoma development by directly targeting TGFB2; By performing quantitative real-time PCR ELISA and luciferase reporter assays transforming growth factor beta2 TGFB2 was validated as a direct target gene of miR-200a; Moreover siRNA-mediated knockdown of TGFB2 partially phenocopied the effect of miR-200a overexpression; These results suggest that miR-200a suppresses RCC development via directly targeting TGFB2 indicating that miR-200a may present a novel target for diagnostic and therapeutic strategies in RCC
119 hsa-miR-203a-3p TGFB2 1.45 0.03941 0.53 0.23727 MirTarget -0.17 0.00022 NA
120 hsa-miR-32-3p TGFB2 0.58 0.11837 0.53 0.23727 mirMAP -0.26 0.00779 NA
121 hsa-miR-330-3p TGFB2 0.8 0.00747 0.53 0.23727 miRNATAP -0.3 0.00575 NA
122 hsa-miR-33a-3p TGFB2 0.35 0.32171 0.53 0.23727 MirTarget; mirMAP -0.4 3.0E-5 NA
123 hsa-miR-375 TGFB2 -2.95 0.0057 0.53 0.23727 miRNAWalker2 validate -0.14 0 NA
124 hsa-miR-429 TGFB2 1.4 0.009 0.53 0.23727 miRNATAP -0.28 0 NA
125 hsa-miR-101-3p TGFBR1 -0.45 0.02834 -0.25 0.2568 miRNAWalker2 validate; miRNATAP -0.33 1.0E-5 NA
126 hsa-miR-126-5p TGFBR1 0.42 0.07532 -0.25 0.2568 mirMAP; miRNATAP -0.2 0.00366 NA
127 hsa-miR-128-3p TGFBR1 0.98 6.0E-5 -0.25 0.2568 miRNAWalker2 validate; miRTarBase -0.24 0.00011 NA
128 hsa-miR-130b-3p TGFBR1 1.33 5.0E-5 -0.25 0.2568 miRNATAP -0.18 0.0001 NA
129 hsa-miR-140-5p TGFBR1 0.21 0.303 -0.25 0.2568 miRNAWalker2 validate; PITA; miRanda; miRNATAP -0.23 0.00361 NA
130 hsa-miR-142-5p TGFBR1 1.56 1.0E-5 -0.25 0.2568 mirMAP -0.15 0.00101 NA
131 hsa-miR-32-3p TGFBR1 0.58 0.11837 -0.25 0.2568 mirMAP; miRNATAP -0.13 0.00671 NA
132 hsa-miR-330-3p TGFBR1 0.8 0.00747 -0.25 0.2568 mirMAP; miRNATAP -0.2 0.0001 NA
133 hsa-miR-429 TGFBR1 1.4 0.009 -0.25 0.2568 miRanda; miRNATAP -0.1 0.00033 NA
134 hsa-miR-769-5p TGFBR1 1.15 0 -0.25 0.2568 PITA; miRNATAP -0.21 0.00106 NA
135 hsa-miR-15a-5p TGFBR3 1.04 0 -2.55 0 MirTarget; miRNATAP -0.72 2.0E-5 NA
136 hsa-miR-15b-5p TGFBR3 1.62 0 -2.55 0 MirTarget; miRNATAP -0.56 1.0E-5 NA
137 hsa-miR-16-2-3p TGFBR3 1.8 0 -2.55 0 mirMAP -0.48 2.0E-5 NA
138 hsa-miR-16-5p TGFBR3 1.01 1.0E-5 -2.55 0 MirTarget; miRNATAP -0.68 2.0E-5 NA
139 hsa-miR-182-5p TGFBR3 0.89 0.03106 -2.55 0 miRNATAP -0.29 0.00089 NA
140 hsa-miR-185-3p TGFBR3 1.34 3.0E-5 -2.55 0 MirTarget; miRNATAP -0.36 0.00097 NA
141 hsa-miR-18a-3p TGFBR3 2.35 0 -2.55 0 MirTarget -0.39 0 NA
142 hsa-miR-18a-5p TGFBR3 2.2 0 -2.55 0 MirTarget -0.43 0 NA
143 hsa-miR-193b-3p TGFBR3 0.28 0.45126 -2.55 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.5 0 NA
144 hsa-miR-21-5p TGFBR3 1.75 0 -2.55 0 miRNAWalker2 validate -1.12 0 NA
145 hsa-miR-222-5p TGFBR3 1.88 0 -2.55 0 MirTarget -0.28 0.00219 NA
146 hsa-miR-23a-3p TGFBR3 1.11 0 -2.55 0 MirTarget; mirMAP -0.76 2.0E-5 NA
147 hsa-miR-27a-3p TGFBR3 1.3 0 -2.55 0 MirTarget; miRNATAP -0.74 0 NA
148 hsa-miR-296-5p TGFBR3 0.93 0.06024 -2.55 0 MirTarget -0.26 0.00062 NA
149 hsa-miR-323b-3p TGFBR3 1.14 0.02148 -2.55 0 miRNATAP -0.24 0.00327 NA
150 hsa-miR-335-3p TGFBR3 2.52 0 -2.55 0 mirMAP -0.27 0.00114 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 EPITHELIAL TO MESENCHYMAL TRANSITION 23 56 9.885e-62 4.6e-58
2 MESENCHYMAL CELL DIFFERENTIATION 23 134 1.365e-51 3.175e-48
3 MESENCHYME DEVELOPMENT 23 190 7.772e-48 9.041e-45
4 STEM CELL DIFFERENTIATION 23 190 7.772e-48 9.041e-45
5 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 23 513 1.574e-37 1.465e-34
6 CELLULAR COMPONENT MORPHOGENESIS 23 900 8.059e-32 6.25e-29
7 CELL DEVELOPMENT 23 1426 3.541e-27 2.354e-24
8 TISSUE DEVELOPMENT 23 1518 1.508e-26 8.769e-24
9 RESPONSE TO GROWTH FACTOR 17 475 1.624e-23 8.394e-21
10 TISSUE MORPHOGENESIS 17 533 1.168e-22 5.437e-20
11 REGULATION OF OSSIFICATION 13 178 1.492e-21 6.313e-19
12 GLAND DEVELOPMENT 15 395 8.849e-21 3.431e-18
13 MESENCHYME MORPHOGENESIS 9 38 9.287e-20 3.324e-17
14 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 18 1021 1.268e-19 4.213e-17
15 REGULATION OF STEM CELL DIFFERENTIATION 11 113 1.452e-19 4.505e-17
16 ORGAN MORPHOGENESIS 17 841 2.735e-19 7.952e-17
17 REGULATION OF EPITHELIAL CELL PROLIFERATION 13 285 7.654e-19 2.095e-16
18 MORPHOGENESIS OF AN EPITHELIUM 14 400 9.072e-19 2.298e-16
19 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 18 1142 9.384e-19 2.298e-16
20 REGULATION OF CELL DIFFERENTIATION 19 1492 2.274e-18 5.291e-16
21 REGULATION OF CELL PROLIFERATION 19 1496 2.392e-18 5.3e-16
22 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 17 1008 5.814e-18 1.23e-15
23 REGULATION OF ORGAN MORPHOGENESIS 12 242 9.005e-18 1.822e-15
24 REGULATION OF CELL DEVELOPMENT 16 836 1.407e-17 2.729e-15
25 SENSORY ORGAN DEVELOPMENT 14 493 1.7e-17 3.164e-15
26 POSITIVE REGULATION OF GENE EXPRESSION 19 1733 3.783e-17 6.771e-15
27 CONNECTIVE TISSUE DEVELOPMENT 11 194 6.567e-17 1.132e-14
28 EMBRYONIC ORGAN DEVELOPMENT 13 406 7.821e-17 1.3e-14
29 TUBE DEVELOPMENT 14 552 8.23e-17 1.321e-14
30 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 16 957 1.196e-16 1.855e-14
31 HEART MORPHOGENESIS 11 212 1.769e-16 2.655e-14
32 REGULATION OF CELLULAR COMPONENT MOVEMENT 15 771 1.987e-16 2.889e-14
33 TUBE MORPHOGENESIS 12 323 2.962e-16 4.177e-14
34 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 7 24 3.305e-16 4.523e-14
35 CARTILAGE DEVELOPMENT 10 147 3.557e-16 4.729e-14
36 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 8 50 4.037e-16 5.218e-14
37 POSITIVE REGULATION OF CELL PROLIFERATION 15 814 4.443e-16 5.587e-14
38 POSITIVE REGULATION OF CELL DIFFERENTIATION 15 823 5.228e-16 6.402e-14
39 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 8 53 6.651e-16 7.936e-14
40 EMBRYO DEVELOPMENT 15 894 1.778e-15 2.068e-13
41 RESPONSE TO ENDOGENOUS STIMULUS 17 1450 2.566e-15 2.912e-13
42 REGULATION OF CARTILAGE DEVELOPMENT 8 63 2.887e-15 3.198e-13
43 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 18 1805 3.157e-15 3.416e-13
44 EPITHELIUM DEVELOPMENT 15 945 4.031e-15 4.262e-13
45 REGULATION OF BINDING 11 283 4.362e-15 4.51e-13
46 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 18 1848 4.779e-15 4.834e-13
47 POSITIVE REGULATION OF LOCOMOTION 12 420 6.908e-15 6.839e-13
48 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 15 983 7.205e-15 6.984e-13
49 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 15 1004 9.834e-15 9.338e-13
50 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 10 207 1.154e-14 1.074e-12
51 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 14 801 1.428e-14 1.303e-12
52 SKELETAL SYSTEM DEVELOPMENT 12 455 1.795e-14 1.606e-12
53 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 17 1672 2.735e-14 2.393e-12
54 POSITIVE REGULATION OF CELL DEVELOPMENT 12 472 2.777e-14 2.393e-12
55 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 16 1360 2.986e-14 2.481e-12
56 NEGATIVE REGULATION OF CELL PROLIFERATION 13 643 2.962e-14 2.481e-12
57 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 10 236 4.325e-14 3.531e-12
58 LOCOMOTION 15 1114 4.526e-14 3.631e-12
59 REGULATION OF STEM CELL PROLIFERATION 8 88 4.712e-14 3.716e-12
60 CELL PROLIFERATION 13 672 5.21e-14 4.041e-12
61 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 9 154 5.601e-14 4.272e-12
62 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 15 1152 7.396e-14 5.551e-12
63 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 17 1784 7.997e-14 5.907e-12
64 ENDOCARDIAL CUSHION MORPHOGENESIS 6 22 8.381e-14 6.094e-12
65 REGULATION OF CELL DEATH 16 1472 1.025e-13 7.338e-12
66 GLAND MORPHOGENESIS 8 97 1.053e-13 7.424e-12
67 MORPHOGENESIS OF A BRANCHING STRUCTURE 9 167 1.174e-13 8.153e-12
68 NEGATIVE REGULATION OF CELL COMMUNICATION 15 1192 1.219e-13 8.338e-12
69 NEGATIVE REGULATION OF GENE EXPRESSION 16 1493 1.278e-13 8.617e-12
70 EMBRYONIC MORPHOGENESIS 12 539 1.343e-13 8.869e-12
71 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 8 100 1.353e-13 8.869e-12
72 PATTERN SPECIFICATION PROCESS 11 418 3.148e-13 2.034e-11
73 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 15 1275 3.255e-13 2.075e-11
74 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 8 115 4.258e-13 2.678e-11
75 UROGENITAL SYSTEM DEVELOPMENT 10 299 4.625e-13 2.869e-11
76 REGULATION OF HEART MORPHOGENESIS 6 29 5.309e-13 3.25e-11
77 NEGATIVE REGULATION OF CELL DIFFERENTIATION 12 609 5.684e-13 3.435e-11
78 REGULATION OF WNT SIGNALING PATHWAY 10 310 6.63e-13 3.955e-11
79 MESODERM MORPHOGENESIS 7 66 7.221e-13 4.253e-11
80 CELL MOTILITY 13 835 8.297e-13 4.663e-11
81 LOCALIZATION OF CELL 13 835 8.297e-13 4.663e-11
82 REGULATION OF CELL ADHESION 12 629 8.318e-13 4.663e-11
83 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 7 67 8.057e-13 4.663e-11
84 REGULATION OF GROWTH 12 633 8.963e-13 4.965e-11
85 ENDOCARDIAL CUSHION DEVELOPMENT 6 32 1.011e-12 5.532e-11
86 HEART DEVELOPMENT 11 466 1.027e-12 5.557e-11
87 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 15 1395 1.204e-12 6.442e-11
88 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 8 131 1.232e-12 6.515e-11
89 NEUROGENESIS 15 1402 1.295e-12 6.771e-11
90 NEGATIVE REGULATION OF CELL DEATH 13 872 1.438e-12 7.433e-11
91 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 6 34 1.498e-12 7.657e-11
92 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 10 337 1.522e-12 7.696e-11
93 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 5 13 1.615e-12 8.081e-11
94 EPITHELIAL CELL DIFFERENTIATION 11 495 1.977e-12 9.787e-11
95 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 9 229 2.055e-12 1.006e-10
96 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 8 144 2.656e-12 1.288e-10
97 DIGESTIVE SYSTEM DEVELOPMENT 8 148 3.317e-12 1.591e-10
98 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 15 1517 4.058e-12 1.927e-10
99 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 11 554 6.68e-12 3.14e-10
100 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 8 162 6.886e-12 3.172e-10
101 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 8 162 6.886e-12 3.172e-10
102 REGULATION OF PROTEIN BINDING 8 168 9.233e-12 4.212e-10
103 REPRODUCTIVE SYSTEM DEVELOPMENT 10 408 1.01e-11 4.563e-10
104 GROWTH 10 410 1.06e-11 4.743e-10
105 CARDIOVASCULAR SYSTEM DEVELOPMENT 12 788 1.169e-11 5.13e-10
106 CIRCULATORY SYSTEM DEVELOPMENT 12 788 1.169e-11 5.13e-10
107 EMBRYONIC ORGAN MORPHOGENESIS 9 279 1.212e-11 5.268e-10
108 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 6 48 1.353e-11 5.827e-10
109 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 11 602 1.635e-11 6.978e-10
110 REGULATION OF MUSCLE TISSUE DEVELOPMENT 7 103 1.79e-11 7.503e-10
111 REGULATION OF MUSCLE ORGAN DEVELOPMENT 7 103 1.79e-11 7.503e-10
112 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 8 190 2.484e-11 1.032e-09
113 CARDIAC MUSCLE TISSUE MORPHOGENESIS 6 54 2.834e-11 1.167e-09
114 FORMATION OF PRIMARY GERM LAYER 7 110 2.861e-11 1.168e-09
115 ANTERIOR POSTERIOR PATTERN SPECIFICATION 8 194 2.935e-11 1.188e-09
116 EAR DEVELOPMENT 8 195 3.059e-11 1.217e-09
117 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 7 111 3.051e-11 1.217e-09
118 IN UTERO EMBRYONIC DEVELOPMENT 9 311 3.197e-11 1.24e-09
119 RESPONSE TO OXYGEN LEVELS 9 311 3.197e-11 1.24e-09
120 REGIONALIZATION 9 311 3.197e-11 1.24e-09
121 REGULATION OF OSTEOBLAST DIFFERENTIATION 7 112 3.252e-11 1.251e-09
122 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 8 197 3.32e-11 1.266e-09
123 NEURON DIFFERENTIATION 12 874 3.903e-11 1.477e-09
124 MESODERM DEVELOPMENT 7 118 4.713e-11 1.768e-09
125 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 6 60 5.47e-11 2.036e-09
126 POSITIVE REGULATION OF STEM CELL PROLIFERATION 6 61 6.062e-11 2.239e-09
127 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 11 689 6.95e-11 2.546e-09
128 KIDNEY EPITHELIUM DEVELOPMENT 7 125 7.093e-11 2.578e-09
129 POSITIVE REGULATION OF BINDING 7 127 7.937e-11 2.863e-09
130 NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT 5 26 8.175e-11 2.926e-09
131 HEAD DEVELOPMENT 11 709 9.435e-11 3.351e-09
132 POSITIVE REGULATION OF CELL COMMUNICATION 14 1532 9.563e-11 3.371e-09
133 CELL FATE COMMITMENT 8 227 1.031e-10 3.606e-09
134 FOREBRAIN DEVELOPMENT 9 357 1.091e-10 3.788e-09
135 POSITIVE REGULATION OF RESPONSE TO STIMULUS 15 1929 1.28e-10 4.411e-09
136 NEGATIVE REGULATION OF OSSIFICATION 6 69 1.301e-10 4.452e-09
137 MUSCLE ORGAN MORPHOGENESIS 6 70 1.422e-10 4.83e-09
138 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 11 740 1.489e-10 5.021e-09
139 CARDIAC MUSCLE TISSUE DEVELOPMENT 7 140 1.581e-10 5.291e-09
140 REGULATION OF CELL MORPHOGENESIS 10 552 1.96e-10 6.513e-09
141 OSSIFICATION 8 251 2.294e-10 7.57e-09
142 RESPONSE TO ABIOTIC STIMULUS 12 1024 2.439e-10 7.992e-09
143 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 14 1656 2.7e-10 8.786e-09
144 GASTRULATION 7 155 3.237e-10 1.046e-08
145 POSITIVE REGULATION OF OSSIFICATION 6 84 4.364e-10 1.4e-08
146 PALATE DEVELOPMENT 6 85 4.692e-10 1.495e-08
147 MUSCLE TISSUE DEVELOPMENT 8 275 4.733e-10 1.498e-08
148 POSITIVE REGULATION OF CELL DEATH 10 605 4.781e-10 1.503e-08
149 REGULATION OF EPITHELIAL CELL MIGRATION 7 166 5.239e-10 1.636e-08
150 MUSCLE STRUCTURE DEVELOPMENT 9 432 5.888e-10 1.818e-08
151 APPENDAGE DEVELOPMENT 7 169 5.94e-10 1.818e-08
152 LIMB DEVELOPMENT 7 169 5.94e-10 1.818e-08
153 MESONEPHROS DEVELOPMENT 6 90 6.655e-10 2.024e-08
154 CENTRAL NERVOUS SYSTEM DEVELOPMENT 11 872 8.499e-10 2.568e-08
155 PROSTATE GLAND DEVELOPMENT 5 41 9.209e-10 2.764e-08
156 NEGATIVE REGULATION OF CELL DEVELOPMENT 8 303 1.019e-09 3.038e-08
157 RESPONSE TO LIPID 11 888 1.03e-09 3.052e-08
158 REGULATION OF MAPK CASCADE 10 660 1.111e-09 3.271e-08
159 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 6 102 1.427e-09 4.175e-08
160 EXOCRINE SYSTEM DEVELOPMENT 5 45 1.497e-09 4.353e-08
161 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 6 103 1.514e-09 4.375e-08
162 CARDIAC CHAMBER MORPHOGENESIS 6 104 1.605e-09 4.583e-08
163 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 6 104 1.605e-09 4.583e-08
164 RESPIRATORY SYSTEM DEVELOPMENT 7 197 1.734e-09 4.921e-08
165 CARDIAC VENTRICLE DEVELOPMENT 6 106 1.802e-09 5.081e-08
166 EYE DEVELOPMENT 8 326 1.813e-09 5.081e-08
167 SKELETAL SYSTEM MORPHOGENESIS 7 201 1.995e-09 5.559e-08
168 DIGESTIVE TRACT MORPHOGENESIS 5 48 2.093e-09 5.729e-08
169 REGULATION OF CELL CYCLE 11 949 2.074e-09 5.729e-08
170 POSITIVE REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 5 48 2.093e-09 5.729e-08
171 DEVELOPMENTAL GROWTH 8 333 2.142e-09 5.829e-08
172 FACE DEVELOPMENT 5 50 2.586e-09 6.996e-08
173 NOTCH SIGNALING PATHWAY 6 114 2.801e-09 7.491e-08
174 SKIN DEVELOPMENT 7 211 2.797e-09 7.491e-08
175 BRANCH ELONGATION OF AN EPITHELIUM 4 17 3.131e-09 8.325e-08
176 REGULATION OF PHOSPHORUS METABOLIC PROCESS 13 1618 3.21e-09 8.487e-08
177 MAMMARY GLAND DEVELOPMENT 6 117 3.278e-09 8.617e-08
178 REPRODUCTION 12 1297 3.643e-09 9.523e-08
179 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 10 750 3.807e-09 9.896e-08
180 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 6 121 4.016e-09 1.038e-07
181 ENDOCRINE SYSTEM DEVELOPMENT 6 123 4.434e-09 1.14e-07
182 REGULATION OF CELLULAR COMPONENT BIOGENESIS 10 767 4.721e-09 1.207e-07
183 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 11 1036 5.202e-09 1.316e-07
184 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 11 1036 5.202e-09 1.316e-07
185 POSITIVE REGULATION OF CELL ADHESION 8 376 5.552e-09 1.396e-07
186 REGULATION OF PROTEIN MODIFICATION PROCESS 13 1710 6.308e-09 1.578e-07
187 POSITIVE REGULATION OF GROWTH 7 238 6.449e-09 1.605e-07
188 STEM CELL PROLIFERATION 5 60 6.616e-09 1.635e-07
189 SENSORY ORGAN MORPHOGENESIS 7 239 6.639e-09 1.635e-07
190 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 6 134 7.43e-09 1.819e-07
191 CARDIAC VENTRICLE MORPHOGENESIS 5 62 7.827e-09 1.907e-07
192 IMMUNE SYSTEM DEVELOPMENT 9 582 7.989e-09 1.936e-07
193 SOMATIC STEM CELL DIVISION 4 22 9.587e-09 2.311e-07
194 CARDIAC CHAMBER DEVELOPMENT 6 144 1.145e-08 2.746e-07
195 PROSTATE GLAND MORPHOGENESIS 4 23 1.16e-08 2.767e-07
196 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 7 262 1.253e-08 2.965e-07
197 ORGAN GROWTH 5 68 1.255e-08 2.965e-07
198 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 11 1135 1.347e-08 3.166e-07
199 RESPONSE TO EXTERNAL STIMULUS 13 1821 1.355e-08 3.168e-07
200 SKIN EPIDERMIS DEVELOPMENT 5 71 1.564e-08 3.621e-07
201 ENDODERM DEVELOPMENT 5 71 1.564e-08 3.621e-07
202 REGULATION OF MUSCLE CELL DIFFERENTIATION 6 152 1.583e-08 3.647e-07
203 POSITIVE REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 4 25 1.654e-08 3.791e-07
204 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 5 75 2.067e-08 4.715e-07
205 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER INVOLVED IN CELLULAR RESPONSE TO CHEMICAL STIMULUS 4 27 2.291e-08 5.176e-07
206 AXIS ELONGATION 4 27 2.291e-08 5.176e-07
207 DIENCEPHALON DEVELOPMENT 5 77 2.363e-08 5.312e-07
208 SOMITE DEVELOPMENT 5 78 2.523e-08 5.644e-07
209 RESPONSE TO ORGANIC CYCLIC COMPOUND 10 917 2.595e-08 5.777e-07
210 ANGIOGENESIS 7 293 2.704e-08 5.991e-07
211 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 4 29 3.096e-08 6.732e-07
212 REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 4 29 3.096e-08 6.732e-07
213 STEM CELL DIVISION 4 29 3.096e-08 6.732e-07
214 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 4 29 3.096e-08 6.732e-07
215 ORGAN REGENERATION 5 83 3.457e-08 7.378e-07
216 HAIR CYCLE 5 83 3.457e-08 7.378e-07
217 PROTEIN PHOSPHORYLATION 10 944 3.416e-08 7.378e-07
218 MOLTING CYCLE 5 83 3.457e-08 7.378e-07
219 REGULATION OF CELLULAR RESPONSE TO STRESS 9 691 3.525e-08 7.489e-07
220 SALIVARY GLAND DEVELOPMENT 4 32 4.677e-08 9.847e-07
221 REGULATION OF ORGAN FORMATION 4 32 4.677e-08 9.847e-07
222 RESPONSE TO STEROID HORMONE 8 497 4.854e-08 1.013e-06
223 REGULATION OF MAP KINASE ACTIVITY 7 319 4.842e-08 1.013e-06
224 HEART VALVE DEVELOPMENT 4 34 6.023e-08 1.251e-06
225 POSITIVE REGULATION OF CELL CYCLE 7 332 6.362e-08 1.316e-06
226 RESPONSE TO BMP 5 94 6.482e-08 1.329e-06
227 CELLULAR RESPONSE TO BMP STIMULUS 5 94 6.482e-08 1.329e-06
228 NEGATIVE REGULATION OF MUSCLE ORGAN DEVELOPMENT 4 36 7.638e-08 1.545e-06
229 NEGATIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 4 36 7.638e-08 1.545e-06
230 HEAD MORPHOGENESIS 4 36 7.638e-08 1.545e-06
231 REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 4 37 8.558e-08 1.724e-06
232 CAMERA TYPE EYE MORPHOGENESIS 5 101 9.304e-08 1.866e-06
233 GLANDULAR EPITHELIAL CELL DIFFERENTIATION 4 39 1.064e-07 2.125e-06
234 REGULATION OF NEURON DIFFERENTIATION 8 554 1.12e-07 2.226e-06
235 ODONTOGENESIS 5 105 1.131e-07 2.239e-06
236 REGULATION OF APOPTOTIC SIGNALING PATHWAY 7 363 1.169e-07 2.305e-06
237 BLOOD VESSEL MORPHOGENESIS 7 364 1.191e-07 2.338e-06
238 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 7 368 1.283e-07 2.508e-06
239 POSITIVE REGULATION OF MOLECULAR FUNCTION 12 1791 1.357e-07 2.632e-06
240 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 6 218 1.354e-07 2.632e-06
241 PITUITARY GLAND DEVELOPMENT 4 42 1.445e-07 2.778e-06
242 REGULATION OF HEART GROWTH 4 42 1.445e-07 2.778e-06
243 NEGATIVE REGULATION OF CELL ADHESION 6 223 1.548e-07 2.964e-06
244 REGULATION OF CELL CELL ADHESION 7 380 1.595e-07 3.042e-06
245 BODY MORPHOGENESIS 4 44 1.75e-07 3.323e-06
246 NEPHRON DEVELOPMENT 5 115 1.784e-07 3.374e-06
247 VENTRICULAR CARDIAC MUSCLE TISSUE DEVELOPMENT 4 45 1.919e-07 3.615e-06
248 REGULATION OF EXTRACELLULAR MATRIX ASSEMBLY 3 11 2.179e-07 4.072e-06
249 EPITHELIAL TO MESENCHYMAL TRANSITION INVOLVED IN ENDOCARDIAL CUSHION FORMATION 3 11 2.179e-07 4.072e-06
250 MUSCLE CELL DIFFERENTIATION 6 237 2.216e-07 4.125e-06
251 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 11 1492 2.243e-07 4.157e-06
252 NEURON PROJECTION MORPHOGENESIS 7 402 2.336e-07 4.314e-06
253 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 5 122 2.397e-07 4.408e-06
254 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 7 406 2.498e-07 4.576e-06
255 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 9 876 2.673e-07 4.877e-06
256 REGULATION OF MESENCHYMAL CELL APOPTOTIC PROCESS 3 12 2.903e-07 5.256e-06
257 REGULATION OF MACROPHAGE CYTOKINE PRODUCTION 3 12 2.903e-07 5.256e-06
258 RESPONSE TO HORMONE 9 893 3.145e-07 5.665e-06
259 REGULATION OF REPRODUCTIVE PROCESS 5 129 3.166e-07 5.665e-06
260 TUBE FORMATION 5 129 3.166e-07 5.665e-06
261 EPIDERMIS DEVELOPMENT 6 253 3.255e-07 5.803e-06
262 NEGATIVE REGULATION OF BINDING 5 131 3.418e-07 6.07e-06
263 MAMMARY GLAND EPITHELIUM DEVELOPMENT 4 53 3.748e-07 6.621e-06
264 CARDIOBLAST DIFFERENTIATION 3 13 3.771e-07 6.621e-06
265 MESENCHYMAL CELL PROLIFERATION 3 13 3.771e-07 6.621e-06
266 CELL GROWTH 5 135 3.97e-07 6.944e-06
267 PHOSPHORYLATION 10 1228 4.021e-07 7.008e-06
268 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 7 437 4.105e-07 7.123e-06
269 EYE MORPHOGENESIS 5 136 4.118e-07 7.123e-06
270 NEGATIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 4 55 4.359e-07 7.484e-06
271 REGULATION OF KIDNEY DEVELOPMENT 4 55 4.359e-07 7.484e-06
272 NEGATIVE REGULATION OF CELL CELL ADHESION 5 138 4.428e-07 7.575e-06
273 SMAD PROTEIN SIGNAL TRANSDUCTION 4 56 4.691e-07 7.937e-06
274 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 4 56 4.691e-07 7.937e-06
275 OUTFLOW TRACT MORPHOGENESIS 4 56 4.691e-07 7.937e-06
276 REGULATION OF PROTEIN LOCALIZATION 9 950 5.301e-07 8.937e-06
277 EMBRYONIC PATTERN SPECIFICATION 4 58 5.41e-07 9.088e-06
278 MUSCLE ORGAN DEVELOPMENT 6 277 5.537e-07 9.268e-06
279 RESPONSE TO ESTRADIOL 5 146 5.858e-07 9.769e-06
280 ENDOCARDIAL CUSHION FORMATION 3 15 5.99e-07 9.849e-06
281 MORPHOGENESIS OF AN EPITHELIAL FOLD 3 15 5.99e-07 9.849e-06
282 REGULATION OF CELL PROLIFERATION INVOLVED IN HEART MORPHOGENESIS 3 15 5.99e-07 9.849e-06
283 STRIATED MUSCLE CELL PROLIFERATION 3 15 5.99e-07 9.849e-06
284 CHONDROCYTE DIFFERENTIATION 4 60 6.209e-07 1.017e-05
285 VASCULATURE DEVELOPMENT 7 469 6.603e-07 1.078e-05
286 POSITIVE REGULATION OF MAPK CASCADE 7 470 6.698e-07 1.082e-05
287 WOUND HEALING 7 470 6.698e-07 1.082e-05
288 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 7 470 6.698e-07 1.082e-05
289 REGULATION OF DEVELOPMENTAL GROWTH 6 289 7.095e-07 1.138e-05
290 SOMITOGENESIS 4 62 7.092e-07 1.138e-05
291 PARAXIAL MESODERM DEVELOPMENT 3 16 7.367e-07 1.174e-05
292 CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN HEART DEVELOPMENT 3 16 7.367e-07 1.174e-05
293 NEUROEPITHELIAL CELL DIFFERENTIATION 4 63 7.567e-07 1.202e-05
294 AMEBOIDAL TYPE CELL MIGRATION 5 154 7.63e-07 1.208e-05
295 NEGATIVE REGULATION OF STEM CELL PROLIFERATION 3 17 8.939e-07 1.405e-05
296 POSITIVE REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 3 17 8.939e-07 1.405e-05
297 REGENERATION 5 161 9.506e-07 1.489e-05
298 NEURON FATE COMMITMENT 4 67 9.707e-07 1.516e-05
299 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 4 68 1.031e-06 1.604e-05
300 PERICARDIUM DEVELOPMENT 3 18 1.072e-06 1.657e-05
301 NOTOCHORD DEVELOPMENT 3 18 1.072e-06 1.657e-05
302 RESPONSE TO OXYGEN CONTAINING COMPOUND 10 1381 1.187e-06 1.829e-05
303 REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 3 19 1.272e-06 1.94e-05
304 MUSCLE CELL PROLIFERATION 3 19 1.272e-06 1.94e-05
305 POSITIVE REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 3 19 1.272e-06 1.94e-05
306 POSITIVE REGULATION OF PROTEIN BINDING 4 73 1.372e-06 2.066e-05
307 EMBRYONIC HEART TUBE DEVELOPMENT 4 73 1.372e-06 2.066e-05
308 REGULATION OF ORGAN GROWTH 4 73 1.372e-06 2.066e-05
309 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 4 73 1.372e-06 2.066e-05
310 GLIOGENESIS 5 175 1.434e-06 2.153e-05
311 REGULATION OF KINASE ACTIVITY 8 776 1.447e-06 2.164e-05
312 NEGATIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 3 20 1.495e-06 2.23e-05
313 NEURAL CREST CELL DIFFERENTIATION 4 75 1.53e-06 2.274e-05
314 NEGATIVE REGULATION OF MOLECULAR FUNCTION 9 1079 1.539e-06 2.281e-05
315 REGULATION OF BMP SIGNALING PATHWAY 4 77 1.701e-06 2.512e-05
316 RENAL TUBULE DEVELOPMENT 4 78 1.791e-06 2.63e-05
317 REGULATION OF PROTEIN IMPORT 5 183 1.787e-06 2.63e-05
318 NEURON PROJECTION DEVELOPMENT 7 545 1.801e-06 2.635e-05
319 NEGATIVE REGULATION OF PROTEIN BINDING 4 79 1.886e-06 2.75e-05
320 EPITHELIAL CELL DEVELOPMENT 5 186 1.936e-06 2.815e-05
321 REGULATION OF CELLULAR PROTEIN LOCALIZATION 7 552 1.961e-06 2.842e-05
322 POSITIVE REGULATION OF MESONEPHROS DEVELOPMENT 3 22 2.017e-06 2.914e-05
323 REGULATION OF RESPONSE TO STRESS 10 1468 2.075e-06 2.99e-05
324 REGULATION OF CELL CYCLE PROCESS 7 558 2.106e-06 3.025e-05
325 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 5 191 2.206e-06 3.158e-05
326 REGULATION OF CYTOKINE PRODUCTION 7 563 2.235e-06 3.18e-05
327 RESPONSE TO WOUNDING 7 563 2.235e-06 3.18e-05
328 EMBRYONIC PLACENTA DEVELOPMENT 4 83 2.299e-06 3.262e-05
329 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO STRESS 3 23 2.318e-06 3.278e-05
330 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 4 85 2.529e-06 3.567e-05
331 RESPONSE TO ALCOHOL 6 362 2.625e-06 3.69e-05
332 EMBRYONIC CAMERA TYPE EYE MORPHOGENESIS 3 24 2.647e-06 3.698e-05
333 NEGATIVE REGULATION OF MYOBLAST DIFFERENTIATION 3 24 2.647e-06 3.698e-05
334 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 5 200 2.765e-06 3.851e-05
335 TISSUE REMODELING 4 87 2.776e-06 3.856e-05
336 POSITIVE REGULATION OF CATALYTIC ACTIVITY 10 1518 2.814e-06 3.897e-05
337 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 3 25 3.005e-06 4.15e-05
338 SEGMENTATION 4 89 3.041e-06 4.186e-05
339 HEART TRABECULA MORPHOGENESIS 3 26 3.395e-06 4.632e-05
340 REGULATION OF MESONEPHROS DEVELOPMENT 3 26 3.395e-06 4.632e-05
341 HEART GROWTH 3 26 3.395e-06 4.632e-05
342 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 4 93 3.625e-06 4.918e-05
343 NEPHRON EPITHELIUM DEVELOPMENT 4 93 3.625e-06 4.918e-05
344 POSITIVE REGULATION OF HEART GROWTH 3 27 3.816e-06 5.132e-05
345 REGULATION OF ASTROCYTE DIFFERENTIATION 3 27 3.816e-06 5.132e-05
346 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 3 27 3.816e-06 5.132e-05
347 CANONICAL WNT SIGNALING PATHWAY 4 95 3.947e-06 5.277e-05
348 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 4 95 3.947e-06 5.277e-05
349 REGULATION OF CELL GROWTH 6 391 4.093e-06 5.456e-05
350 CARDIOCYTE DIFFERENTIATION 4 96 4.115e-06 5.471e-05
351 RESPONSE TO ESTROGEN 5 218 4.214e-06 5.586e-05
352 VENTRICULAR SEPTUM MORPHOGENESIS 3 28 4.271e-06 5.614e-05
353 REGULATION OF NEUROBLAST PROLIFERATION 3 28 4.271e-06 5.614e-05
354 MAMMARY GLAND DUCT MORPHOGENESIS 3 28 4.271e-06 5.614e-05
355 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 5 220 4.406e-06 5.775e-05
356 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 4 98 4.468e-06 5.84e-05
357 EPIDERMIS MORPHOGENESIS 3 29 4.76e-06 6.187e-05
358 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 3 29 4.76e-06 6.187e-05
359 CELL PART MORPHOGENESIS 7 633 4.849e-06 6.285e-05
360 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 6 404 4.939e-06 6.383e-05
361 TELENCEPHALON DEVELOPMENT 5 228 5.244e-06 6.759e-05
362 REGULATION OF VASCULATURE DEVELOPMENT 5 233 5.829e-06 7.492e-05
363 REGULATION OF FAT CELL DIFFERENTIATION 4 106 6.107e-06 7.829e-05
364 REGULATION OF CELLULAR LOCALIZATION 9 1277 6.184e-06 7.906e-05
365 NEGATIVE REGULATION OF GROWTH 5 236 6.203e-06 7.908e-05
366 REGULATION OF TRANSFERASE ACTIVITY 8 946 6.318e-06 8.032e-05
367 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO HYPOXIA 3 32 6.447e-06 8.174e-05
368 REGULATION OF T CELL APOPTOTIC PROCESS 3 33 7.087e-06 8.912e-05
369 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 3 33 7.087e-06 8.912e-05
370 EMBRYONIC EYE MORPHOGENESIS 3 33 7.087e-06 8.912e-05
371 NEGATIVE REGULATION OF CELL CYCLE 6 433 7.346e-06 9.213e-05
372 EAR MORPHOGENESIS 4 112 7.601e-06 9.507e-05
373 ORGAN FORMATION 3 34 7.767e-06 9.637e-05
374 REGULATION OF MESENCHYMAL CELL PROLIFERATION 3 34 7.767e-06 9.637e-05
375 POSITIVE REGULATION OF CELL CYCLE PROCESS 5 247 7.74e-06 9.637e-05
376 NEURON DEVELOPMENT 7 687 8.296e-06 0.0001027
377 EMBRYONIC CAMERA TYPE EYE DEVELOPMENT 3 35 8.488e-06 0.0001048
378 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 4 117 9.039e-06 0.0001113
379 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 4 118 9.349e-06 0.0001148
380 CELL DEATH 8 1001 9.575e-06 0.0001172
381 CELLULAR RESPONSE TO LIPID 6 457 9.993e-06 0.000122
382 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 3 37 1.006e-05 0.0001226
383 CELL DIVISION 6 460 1.037e-05 0.000126
384 NEGATIVE REGULATION OF LOCOMOTION 5 263 1.049e-05 0.0001271
385 TAXIS 6 464 1.09e-05 0.0001313
386 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 3 38 1.092e-05 0.0001313
387 POSITIVE REGULATION OF ORGAN GROWTH 3 38 1.092e-05 0.0001313
388 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 6 465 1.103e-05 0.0001323
389 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 7 724 1.168e-05 0.0001397
390 ANATOMICAL STRUCTURE MATURATION 3 39 1.182e-05 0.0001406
391 TRABECULA MORPHOGENESIS 3 39 1.182e-05 0.0001406
392 OSTEOBLAST DIFFERENTIATION 4 126 1.212e-05 0.0001439
393 REGULATION OF CELL DIVISION 5 272 1.235e-05 0.0001462
394 MAMMARY GLAND MORPHOGENESIS 3 40 1.277e-05 0.0001504
395 POSITIVE REGULATION OF CELL MATRIX ADHESION 3 40 1.277e-05 0.0001504
396 HEPATICOBILIARY SYSTEM DEVELOPMENT 4 128 1.29e-05 0.0001515
397 PROTEIN LOCALIZATION 10 1805 1.332e-05 0.0001561
398 POSITIVE REGULATION OF KINASE ACTIVITY 6 482 1.353e-05 0.0001582
399 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 3 41 1.376e-05 0.0001605
400 ACTIVATION OF PROTEIN KINASE ACTIVITY 5 279 1.396e-05 0.0001624
401 POSITIVE REGULATION OF CELL DIVISION 4 132 1.456e-05 0.0001686
402 MAINTENANCE OF CELL NUMBER 4 132 1.456e-05 0.0001686
403 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 3 42 1.481e-05 0.000171
404 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 3 43 1.591e-05 0.0001828
405 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 4 135 1.591e-05 0.0001828
406 GLIAL CELL DIFFERENTIATION 4 136 1.638e-05 0.0001878
407 CELL CELL SIGNALING 7 767 1.699e-05 0.0001942
408 LABYRINTHINE LAYER DEVELOPMENT 3 44 1.706e-05 0.0001946
409 MULTICELLULAR ORGANISM REPRODUCTION 7 768 1.713e-05 0.0001949
410 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 4 138 1.735e-05 0.0001965
411 PLACENTA DEVELOPMENT 4 138 1.735e-05 0.0001965
412 LUNG MORPHOGENESIS 3 45 1.827e-05 0.0002063
413 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 6 514 1.947e-05 0.0002193
414 REGULATION OF CHONDROCYTE DIFFERENTIATION 3 46 1.953e-05 0.0002195
415 CELLULAR RESPONSE TO OXYGEN LEVELS 4 143 1.996e-05 0.0002233
416 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 4 143 1.996e-05 0.0002233
417 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 5 303 2.077e-05 0.0002317
418 EXTRACELLULAR STRUCTURE ORGANIZATION 5 304 2.11e-05 0.0002349
419 POSITIVE REGULATION OF NEURON DIFFERENTIATION 5 306 2.178e-05 0.0002418
420 REGULATION OF PROTEIN TARGETING 5 307 2.212e-05 0.0002451
421 REGULATION OF MYOBLAST DIFFERENTIATION 3 48 2.221e-05 0.0002455
422 POSITIVE REGULATION OF CELL GROWTH 4 148 2.285e-05 0.000252
423 NEURAL TUBE DEVELOPMENT 4 149 2.346e-05 0.0002581
424 CARDIAC SEPTUM MORPHOGENESIS 3 49 2.365e-05 0.0002595
425 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 4 152 2.537e-05 0.0002778
426 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 4 153 2.604e-05 0.000283
427 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 6 541 2.598e-05 0.000283
428 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 6 541 2.598e-05 0.000283
429 RESPONSE TO ACID CHEMICAL 5 319 2.659e-05 0.0002883
430 ARTERY MORPHOGENESIS 3 51 2.669e-05 0.0002888
431 BONE DEVELOPMENT 4 156 2.81e-05 0.0003019
432 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 4 156 2.81e-05 0.0003019
433 PROTEIN LOCALIZATION TO NUCLEUS 4 156 2.81e-05 0.0003019
434 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 10 1977 2.971e-05 0.0003186
435 MESONEPHRIC TUBULE MORPHOGENESIS 3 53 2.997e-05 0.0003206
436 PROTEIN LOCALIZATION TO ORGANELLE 6 556 3.03e-05 0.0003234
437 IMMUNE SYSTEM PROCESS 10 1984 3.065e-05 0.0003263
438 REGULATION OF ORGANELLE ORGANIZATION 8 1178 3.128e-05 0.0003323
439 REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 3 54 3.171e-05 0.0003354
440 VENTRICULAR SEPTUM DEVELOPMENT 3 54 3.171e-05 0.0003354
441 CELLULAR RESPONSE TO BIOTIC STIMULUS 4 163 3.337e-05 0.000352
442 CRANIAL SKELETAL SYSTEM DEVELOPMENT 3 55 3.352e-05 0.0003529
443 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 57 3.733e-05 0.0003921
444 SECRETION 6 588 4.146e-05 0.0004335
445 REGULATION OF GLIAL CELL DIFFERENTIATION 3 59 4.141e-05 0.0004335
446 REGULATION OF CELL SUBSTRATE ADHESION 4 173 4.211e-05 0.0004393
447 RESPONSE TO BIOTIC STIMULUS 7 886 4.296e-05 0.0004472
448 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 3 60 4.356e-05 0.0004504
449 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 3 60 4.356e-05 0.0004504
450 OLIGODENDROCYTE DIFFERENTIATION 3 60 4.356e-05 0.0004504
451 HOMEOSTASIS OF NUMBER OF CELLS 4 175 4.404e-05 0.0004544
452 RESPONSE TO CORTICOSTEROID 4 176 4.503e-05 0.0004635
453 EMBRYONIC DIGIT MORPHOGENESIS 3 61 4.578e-05 0.0004691
454 REGULATION OF VIRAL TRANSCRIPTION 3 61 4.578e-05 0.0004691
455 CELL PROJECTION ORGANIZATION 7 902 4.816e-05 0.0004903
456 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 3 62 4.807e-05 0.0004903
457 EMBRYONIC HEART TUBE MORPHOGENESIS 3 62 4.807e-05 0.0004903
458 RESPONSE TO KETONE 4 182 5.131e-05 0.0005213
459 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 6 616 5.374e-05 0.0005436
460 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 6 616 5.374e-05 0.0005436
461 CELL JUNCTION ORGANIZATION 4 185 5.469e-05 0.000552
462 REGULATION OF CHEMOKINE PRODUCTION 3 65 5.539e-05 0.0005566
463 REGULATION OF RESPONSE TO OXIDATIVE STRESS 3 65 5.539e-05 0.0005566
464 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 3 66 5.798e-05 0.0005765
465 SOMATIC STEM CELL POPULATION MAINTENANCE 3 66 5.798e-05 0.0005765
466 FOREBRAIN GENERATION OF NEURONS 3 66 5.798e-05 0.0005765
467 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 3 66 5.798e-05 0.0005765
468 LENS DEVELOPMENT IN CAMERA TYPE EYE 3 66 5.798e-05 0.0005765
469 MYELOID CELL DIFFERENTIATION 4 189 5.943e-05 0.0005896
470 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 3 67 6.066e-05 0.0006005
471 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 5 381 6.197e-05 0.0006122
472 REGULATION OF CELL JUNCTION ASSEMBLY 3 68 6.341e-05 0.0006251
473 DEVELOPMENTAL MATURATION 4 193 6.447e-05 0.0006342
474 ENDOCARDIUM DEVELOPMENT 2 11 6.914e-05 0.0006716
475 RESPONSE TO FOLLICLE STIMULATING HORMONE 2 11 6.914e-05 0.0006716
476 PROSTATE GLAND GROWTH 2 11 6.914e-05 0.0006716
477 EPITHELIAL CELL DIFFERENTIATION INVOLVED IN PROSTATE GLAND DEVELOPMENT 2 11 6.914e-05 0.0006716
478 VENTRICULAR TRABECULA MYOCARDIUM MORPHOGENESIS 2 11 6.914e-05 0.0006716
479 PROSTATE GLANDULAR ACINUS DEVELOPMENT 2 11 6.914e-05 0.0006716
480 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 4 197 6.982e-05 0.0006768
481 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 3 71 7.215e-05 0.0006965
482 CELL FATE SPECIFICATION 3 71 7.215e-05 0.0006965
483 REGULATION OF HYDROLASE ACTIVITY 8 1327 7.33e-05 0.0007061
484 NEURON PROJECTION GUIDANCE 4 205 8.147e-05 0.0007832
485 CARDIAC LEFT VENTRICLE MORPHOGENESIS 2 12 8.291e-05 0.0007857
486 REGULATION OF TIMING OF CELL DIFFERENTIATION 2 12 8.291e-05 0.0007857
487 REGULATION OF THYMOCYTE APOPTOTIC PROCESS 2 12 8.291e-05 0.0007857
488 POSITIVE REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 2 12 8.291e-05 0.0007857
489 REGULATION OF DEVELOPMENT HETEROCHRONIC 2 12 8.291e-05 0.0007857
490 POSITIVE REGULATION OF ASTROCYTE DIFFERENTIATION 2 12 8.291e-05 0.0007857
491 NEGATIVE REGULATION OF RECEPTOR BINDING 2 12 8.291e-05 0.0007857
492 POSITIVE REGULATION OF MAP KINASE ACTIVITY 4 207 8.459e-05 8e-04
493 ARTERY DEVELOPMENT 3 75 8.499e-05 0.0008005
494 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 3 75 8.499e-05 0.0008005
495 POSITIVE REGULATION OF PROTEIN SECRETION 4 211 9.109e-05 0.0008545
496 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 4 211 9.109e-05 0.0008545
497 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 6 684 9.601e-05 0.0008988
498 NEURONAL STEM CELL DIVISION 2 13 9.792e-05 0.000904
499 LEFT RIGHT AXIS SPECIFICATION 2 13 9.792e-05 0.000904
500 CELLULAR RESPONSE TO HEPATOCYTE GROWTH FACTOR STIMULUS 2 13 9.792e-05 0.000904
501 HEART VALVE FORMATION 2 13 9.792e-05 0.000904
502 RESPONSE TO HEPATOCYTE GROWTH FACTOR 2 13 9.792e-05 0.000904
503 NEUROBLAST DIVISION 2 13 9.792e-05 0.000904
504 POSITIVE REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 2 13 9.792e-05 0.000904
505 REGULATION OF TRANSPORT 9 1804 9.819e-05 0.0009047
506 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 3 79 9.923e-05 0.0009107
507 BONE MORPHOGENESIS 3 79 9.923e-05 0.0009107
508 NEGATIVE REGULATION OF PHOSPHORYLATION 5 422 0.0001004 0.0009197
509 CELLULAR RESPONSE TO MECHANICAL STIMULUS 3 80 0.000103 0.0009418
510 KIDNEY MORPHOGENESIS 3 82 0.0001109 0.001012
511 CELL MIGRATION INVOLVED IN HEART DEVELOPMENT 2 14 0.0001142 0.001027
512 SPECIFICATION OF ORGAN IDENTITY 2 14 0.0001142 0.001027
513 CELL MIGRATION INVOLVED IN GASTRULATION 2 14 0.0001142 0.001027
514 REGULATION OF GLOMERULUS DEVELOPMENT 2 14 0.0001142 0.001027
515 EMBRYONIC SKELETAL JOINT DEVELOPMENT 2 14 0.0001142 0.001027
516 POSITIVE REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 2 14 0.0001142 0.001027
517 REGULATION OF EXTRACELLULAR MATRIX DISASSEMBLY 2 14 0.0001142 0.001027
518 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 5 437 0.0001183 0.001063
519 CARDIAC SEPTUM DEVELOPMENT 3 85 0.0001234 0.001106
520 OTIC VESICLE DEVELOPMENT 2 15 0.0001316 0.001171
521 POSITIVE REGULATION OF T CELL APOPTOTIC PROCESS 2 15 0.0001316 0.001171
522 EPITHELIAL CELL FATE COMMITMENT 2 15 0.0001316 0.001171
523 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 4 232 0.0001314 0.001171
524 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 3 88 0.0001368 0.001215
525 REGULATION OF CATABOLIC PROCESS 6 731 0.0001383 0.001226
526 INFLAMMATORY RESPONSE 5 454 0.0001415 0.001249
527 EPITHELIAL CELL PROLIFERATION 3 89 0.0001414 0.001249
528 AXIS SPECIFICATION 3 90 0.0001462 0.001284
529 REGULATION OF CELL MATRIX ADHESION 3 90 0.0001462 0.001284
530 REGULATION OF GLIOGENESIS 3 90 0.0001462 0.001284
531 NEGATIVE REGULATION OF TRANSPORT 5 458 0.0001474 0.001292
532 REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 2 16 0.0001503 0.001305
533 MORPHOGENESIS OF AN ENDOTHELIUM 2 16 0.0001503 0.001305
534 APOPTOTIC PROCESS INVOLVED IN MORPHOGENESIS 2 16 0.0001503 0.001305
535 ATRIOVENTRICULAR VALVE MORPHOGENESIS 2 16 0.0001503 0.001305
536 BRANCHING INVOLVED IN SALIVARY GLAND MORPHOGENESIS 2 16 0.0001503 0.001305
537 CELL CYCLE PROCESS 7 1081 0.0001508 0.001307
538 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 7 1087 0.0001561 0.001348
539 INNER EAR MORPHOGENESIS 3 92 0.0001561 0.001348
540 POSITIVE REGULATION OF CELL CELL ADHESION 4 243 0.000157 0.001353
541 REGULATION OF DNA BINDING 3 93 0.0001611 0.001386
542 NEURAL TUBE FORMATION 3 94 0.0001663 0.001428
543 NEGATIVE REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 2 17 0.0001703 0.001446
544 REGULATION OF RECEPTOR BINDING 2 17 0.0001703 0.001446
545 ESTABLISHMENT OF TISSUE POLARITY 2 17 0.0001703 0.001446
546 NEGATIVE REGULATION OF ANOIKIS 2 17 0.0001703 0.001446
547 REGULATION OF STEM CELL POPULATION MAINTENANCE 2 17 0.0001703 0.001446
548 NEGATIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 2 17 0.0001703 0.001446
549 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 3 95 0.0001716 0.001455
550 MYELOID LEUKOCYTE DIFFERENTIATION 3 96 0.000177 0.001498
551 REGULATION OF CYTOPLASMIC TRANSPORT 5 481 0.0001853 0.001565
552 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 3 98 0.0001882 0.001586
553 REGULATION OF HORMONE BIOSYNTHETIC PROCESS 2 18 0.0001914 0.001608
554 NEPHRON TUBULE FORMATION 2 18 0.0001914 0.001608
555 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 3 99 0.0001939 0.001617
556 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 3 99 0.0001939 0.001617
557 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 3 99 0.0001939 0.001617
558 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 3 99 0.0001939 0.001617
559 SECRETION BY CELL 5 486 0.0001944 0.001618
560 MODIFICATION OF MORPHOLOGY OR PHYSIOLOGY OF OTHER ORGANISM 3 100 0.0001997 0.001654
561 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 3 100 0.0001997 0.001654
562 LIMBIC SYSTEM DEVELOPMENT 3 100 0.0001997 0.001654
563 KERATINOCYTE DIFFERENTIATION 3 101 0.0002057 0.001697
564 REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 3 101 0.0002057 0.001697
565 CELLULAR RESPONSE TO ABIOTIC STIMULUS 4 263 0.0002125 0.00175
566 ATRIOVENTRICULAR VALVE DEVELOPMENT 2 19 0.0002138 0.001757
567 AGING 4 264 0.0002156 0.00177
568 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 5 498 0.0002177 0.001784
569 SEX DIFFERENTIATION 4 266 0.0002219 0.001815
570 POSITIVE REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 2 20 0.0002374 0.001917
571 NEGATIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 2 20 0.0002374 0.001917
572 REGULATION OF SMOOTH MUSCLE CELL DIFFERENTIATION 2 20 0.0002374 0.001917
573 TRACHEA DEVELOPMENT 2 20 0.0002374 0.001917
574 FAT CELL DIFFERENTIATION 3 106 0.0002372 0.001917
575 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 2 20 0.0002374 0.001917
576 MYELOID DENDRITIC CELL DIFFERENTIATION 2 20 0.0002374 0.001917
577 PLATELET DEGRANULATION 3 107 0.0002439 0.001967
578 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 4 274 0.0002485 0.002001
579 POSITIVE REGULATION OF NEUROBLAST PROLIFERATION 2 21 0.0002622 0.002082
580 LEFT RIGHT PATTERN FORMATION 2 21 0.0002622 0.002082
581 CELL AGGREGATION 2 21 0.0002622 0.002082
582 APOPTOTIC PROCESS INVOLVED IN DEVELOPMENT 2 21 0.0002622 0.002082
583 POSITIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 2 21 0.0002622 0.002082
584 COCHLEA MORPHOGENESIS 2 21 0.0002622 0.002082
585 NEGATIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 2 21 0.0002622 0.002082
586 CARTILAGE CONDENSATION 2 21 0.0002622 0.002082
587 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 6 829 0.0002742 0.002174
588 RESPONSE TO BACTERIUM 5 528 0.0002855 0.002259
589 NEGATIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 2 22 0.0002882 0.002269
590 MODULATION OF TRANSCRIPTION IN OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 2 22 0.0002882 0.002269
591 EMBRYONIC PLACENTA MORPHOGENESIS 2 22 0.0002882 0.002269
592 REGULATION OF ENDOTHELIAL CELL MIGRATION 3 114 0.0002939 0.002306
593 REGULATION OF EMBRYONIC DEVELOPMENT 3 114 0.0002939 0.002306
594 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 4 289 0.0003044 0.002385
595 RESPONSE TO FIBROBLAST GROWTH FACTOR 3 116 0.0003094 0.002419
596 REGULATION OF OSTEOBLAST PROLIFERATION 2 23 0.0003154 0.002458
597 REGULATION OF SUPEROXIDE METABOLIC PROCESS 2 23 0.0003154 0.002458
598 SPECIFICATION OF SYMMETRY 3 117 0.0003173 0.002464
599 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 3 117 0.0003173 0.002464
600 NEGATIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 2 24 0.0003438 0.002636
601 NEGATIVE REGULATION OF STEROID METABOLIC PROCESS 2 24 0.0003438 0.002636
602 CYTOKINE PRODUCTION 3 120 0.0003417 0.002636
603 RESPONSE TO STEROL 2 24 0.0003438 0.002636
604 POSITIVE REGULATION OF CELL JUNCTION ASSEMBLY 2 24 0.0003438 0.002636
605 REGULATION OF ODONTOGENESIS 2 24 0.0003438 0.002636
606 REGULATION OF ANOIKIS 2 24 0.0003438 0.002636
607 CELLULAR MACROMOLECULE LOCALIZATION 7 1234 0.0003417 0.002636
608 CELLULAR RESPONSE TO HORMONE STIMULUS 5 552 0.0003504 0.002677
609 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 3 121 0.0003502 0.002677
610 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 3 122 0.0003587 0.002736
611 REGULATION OF CELL PROJECTION ORGANIZATION 5 558 0.0003683 0.002804
612 CELLULAR RESPONSE TO EPIDERMAL GROWTH FACTOR STIMULUS 2 25 0.0003735 0.002826
613 EPITHELIAL TUBE BRANCHING INVOLVED IN LUNG MORPHOGENESIS 2 25 0.0003735 0.002826
614 LUNG CELL DIFFERENTIATION 2 25 0.0003735 0.002826
615 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 2 25 0.0003735 0.002826
616 DEVELOPMENTAL PROGRAMMED CELL DEATH 2 26 0.0004043 0.00301
617 NEGATIVE REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 2 26 0.0004043 0.00301
618 NEGATIVE REGULATION OF GLIAL CELL DIFFERENTIATION 2 26 0.0004043 0.00301
619 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 2 26 0.0004043 0.00301
620 MESODERMAL CELL DIFFERENTIATION 2 26 0.0004043 0.00301
621 REGULATION OF HORMONE METABOLIC PROCESS 2 26 0.0004043 0.00301
622 REGULATION OF P38MAPK CASCADE 2 26 0.0004043 0.00301
623 MYELOID DENDRITIC CELL ACTIVATION 2 26 0.0004043 0.00301
624 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 2 26 0.0004043 0.00301
625 REGULATION OF CELL FATE COMMITMENT 2 26 0.0004043 0.00301
626 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 5 573 0.0004159 0.003091
627 REGULATION OF HEMOPOIESIS 4 314 0.0004169 0.003094
628 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 3 129 0.0004224 0.00313
629 DEVELOPMENTAL INDUCTION 2 27 0.0004363 0.003212
630 INFLAMMATORY RESPONSE TO ANTIGENIC STIMULUS 2 27 0.0004363 0.003212
631 RESPONSE TO LITHIUM ION 2 27 0.0004363 0.003212
632 SUBSTRATE DEPENDENT CELL MIGRATION 2 27 0.0004363 0.003212
633 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 4 321 0.0004531 0.003331
634 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 3 133 0.0004619 0.00339
635 POSITIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 2 28 0.0004696 0.003419
636 AUDITORY RECEPTOR CELL DIFFERENTIATION 2 28 0.0004696 0.003419
637 MORPHOGENESIS OF A POLARIZED EPITHELIUM 2 28 0.0004696 0.003419
638 DOPAMINERGIC NEURON DIFFERENTIATION 2 28 0.0004696 0.003419
639 RESPONSE TO GONADOTROPIN 2 28 0.0004696 0.003419
640 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 3 135 0.0004825 0.003508
641 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 6 926 0.0004964 0.003603
642 NEGATIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 2 29 0.000504 0.003641
643 NEUROBLAST PROLIFERATION 2 29 0.000504 0.003641
644 ACTIVATION OF MAPK ACTIVITY 3 137 0.0005037 0.003641
645 CELL CYCLE 7 1316 0.0005054 0.003646
646 RESPONSE TO METAL ION 4 333 0.0005204 0.003748
647 POSITIVE REGULATION OF TRANSPORT 6 936 0.0005256 0.00378
648 PROTEIN EXPORT FROM NUCLEUS 2 30 0.0005396 0.003845
649 PROTEIN LOCALIZATION TO CYTOSKELETON 2 30 0.0005396 0.003845
650 SMOOTH MUSCLE CELL DIFFERENTIATION 2 30 0.0005396 0.003845
651 RESPONSE TO EPIDERMAL GROWTH FACTOR 2 30 0.0005396 0.003845
652 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 2 30 0.0005396 0.003845
653 CELLULAR RESPONSE TO CYTOKINE STIMULUS 5 606 0.0005372 0.003845
654 EPIDERMAL CELL DIFFERENTIATION 3 142 0.0005592 0.003978
655 REGULATION OF DNA METABOLIC PROCESS 4 340 0.0005627 0.003997
656 HYALURONAN METABOLIC PROCESS 2 31 0.0005764 0.004076
657 CARDIAC ATRIUM DEVELOPMENT 2 31 0.0005764 0.004076
658 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 2 31 0.0005764 0.004076
659 REGULATION OF INTRACELLULAR TRANSPORT 5 621 0.0006004 0.004239
660 POSITIVE REGULATION OF GLIAL CELL DIFFERENTIATION 2 32 0.0006144 0.004312
661 POSITIVE REGULATION OF BMP SIGNALING PATHWAY 2 32 0.0006144 0.004312
662 POSITIVE REGULATION OF EPIDERMIS DEVELOPMENT 2 32 0.0006144 0.004312
663 BLOOD VESSEL REMODELING 2 32 0.0006144 0.004312
664 PEPTIDYL SERINE MODIFICATION 3 148 0.0006308 0.004414
665 MALE SEX DIFFERENTIATION 3 148 0.0006308 0.004414
666 WNT SIGNALING PATHWAY 4 351 0.0006342 0.004431
667 DENDRITIC CELL DIFFERENTIATION 2 33 0.0006536 0.004539
668 EMBRYONIC AXIS SPECIFICATION 2 33 0.0006536 0.004539
669 RESPONSE TO VITAMIN D 2 33 0.0006536 0.004539
670 POSITIVE REGULATION OF RESPONSE TO CYTOKINE STIMULUS 2 33 0.0006536 0.004539
671 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 3 152 0.0006817 0.004727
672 FOREBRAIN NEURON DEVELOPMENT 2 34 0.000694 0.00479
673 LUNG EPITHELIUM DEVELOPMENT 2 34 0.000694 0.00479
674 PROTEIN KINASE B SIGNALING 2 34 0.000694 0.00479
675 PALLIUM DEVELOPMENT 3 153 0.0006948 0.00479
676 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 4 360 0.0006973 0.004799
677 CELL CYCLE ARREST 3 154 0.0007081 0.004867
678 NEGATIVE REGULATION OF RESPONSE TO OXIDATIVE STRESS 2 35 0.0007355 0.005018
679 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 3 156 0.0007351 0.005018
680 HAIR CELL DIFFERENTIATION 2 35 0.0007355 0.005018
681 NEGATIVE REGULATION OF CELLULAR RESPONSE TO OXIDATIVE STRESS 2 35 0.0007355 0.005018
682 REGULATION OF RESPONSE TO REACTIVE OXYGEN SPECIES 2 35 0.0007355 0.005018
683 REGULATION OF IMMUNE SYSTEM PROCESS 7 1403 0.0007431 0.005063
684 REGULATION OF DEPHOSPHORYLATION 3 158 0.0007628 0.005189
685 POSITIVE REGULATION OF CYTOKINE PRODUCTION 4 370 0.0007725 0.005239
686 POSITIVE REGULATION OF SECRETION 4 370 0.0007725 0.005239
687 POSITIVE REGULATION OF PROTEIN ACETYLATION 2 36 0.0007783 0.005256
688 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 2 36 0.0007783 0.005256
689 POSITIVE CHEMOTAXIS 2 36 0.0007783 0.005256
690 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 4 372 0.0007882 0.005315
691 CELL CHEMOTAXIS 3 162 0.0008201 0.00552
692 NEGATIVE REGULATION OF GLIOGENESIS 2 37 0.0008221 0.00552
693 MYOBLAST DIFFERENTIATION 2 37 0.0008221 0.00552
694 POSITIVE REGULATION OF HEMOPOIESIS 3 163 0.0008349 0.005589
695 REGULATION OF NUCLEAR DIVISION 3 163 0.0008349 0.005589
696 COLLAGEN FIBRIL ORGANIZATION 2 38 0.0008672 0.005781
697 BONE MINERALIZATION 2 38 0.0008672 0.005781
698 CYTOKINE SECRETION 2 38 0.0008672 0.005781
699 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 3 166 0.0008801 0.005859
700 POSITIVE REGULATION OF VIRAL TRANSCRIPTION 2 39 0.0009135 0.00602
701 NEGATIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 2 39 0.0009135 0.00602
702 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 2 39 0.0009135 0.00602
703 REGULATION OF CELL ADHESION MEDIATED BY INTEGRIN 2 39 0.0009135 0.00602
704 ASTROCYTE DIFFERENTIATION 2 39 0.0009135 0.00602
705 COCHLEA DEVELOPMENT 2 39 0.0009135 0.00602
706 NEGATIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 2 39 0.0009135 0.00602
707 REGULATION OF PROTEIN SECRETION 4 389 0.0009309 0.006127
708 NEGATIVE REGULATION OF CELL GROWTH 3 170 0.0009429 0.006197
709 ENDOCRINE PANCREAS DEVELOPMENT 2 40 0.0009609 0.006288
710 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 2 40 0.0009609 0.006288
711 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 3 171 0.000959 0.006288
712 REGULATION OF PROTEIN CATABOLIC PROCESS 4 393 0.000967 0.006319
713 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 3 172 0.0009753 0.006356
714 REGULATION OF CELL SIZE 3 172 0.0009753 0.006356
715 POSITIVE REGULATION OF CATABOLIC PROCESS 4 395 0.0009854 0.006413
716 STRIATED MUSCLE CELL DIFFERENTIATION 3 173 0.0009918 0.006445
717 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 2 41 0.001009 0.006542
718 LUNG ALVEOLUS DEVELOPMENT 2 41 0.001009 0.006542
719 CELLULAR RESPONSE TO ACID CHEMICAL 3 175 0.001025 0.006626
720 REGULATION OF SECRETION 5 699 0.001024 0.006626
721 POSITIVE REGULATION OF DNA BINDING 2 42 0.001059 0.006816
722 POSITIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 2 42 0.001059 0.006816
723 GENITALIA DEVELOPMENT 2 42 0.001059 0.006816
724 RESPONSE TO PEPTIDE 4 404 0.001071 0.006885
725 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 2 43 0.00111 0.007098
726 MORPHOGENESIS OF AN EPITHELIAL SHEET 2 43 0.00111 0.007098
727 REGULATION OF NEURON PROJECTION DEVELOPMENT 4 408 0.001111 0.007098
728 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 2 43 0.00111 0.007098
729 REGULATION OF CHEMOTAXIS 3 180 0.001112 0.007098
730 RESPONSE TO CYTOKINE 5 714 0.001126 0.00718
731 NEGATIVE REGULATION OF LIPID BIOSYNTHETIC PROCESS 2 44 0.001162 0.007387
732 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 2 44 0.001162 0.007387
733 POSITIVE REGULATION OF DNA METABOLIC PROCESS 3 185 0.001203 0.007639
734 SPROUTING ANGIOGENESIS 2 45 0.001215 0.007694
735 REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 2 45 0.001215 0.007694
736 IMMUNE RESPONSE 6 1100 0.001227 0.007759
737 PROTEIN COMPLEX SUBUNIT ORGANIZATION 7 1527 0.001229 0.007759
738 NEGATIVE REGULATION OF DNA BINDING 2 46 0.00127 0.007962
739 PEPTIDYL THREONINE MODIFICATION 2 46 0.00127 0.007962
740 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 2 46 0.00127 0.007962
741 REGULATION OF OXIDATIVE STRESS INDUCED CELL DEATH 2 46 0.00127 0.007962
742 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 2 46 0.00127 0.007962
743 POSITIVE REGULATION OF DEPHOSPHORYLATION 2 47 0.001325 0.008276
744 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 2 47 0.001325 0.008276
745 POSITIVE REGULATION OF GLIOGENESIS 2 47 0.001325 0.008276
746 REGULATION OF NEURON APOPTOTIC PROCESS 3 192 0.001339 0.008351
747 RESPONSE TO DRUG 4 431 0.001361 0.008476
748 COLUMNAR CUBOIDAL EPITHELIAL CELL DEVELOPMENT 2 48 0.001382 0.008584
749 ANTERIOR POSTERIOR AXIS SPECIFICATION 2 48 0.001382 0.008584
750 CELLULAR RESPONSE TO STRESS 7 1565 0.00142 0.008809
751 REGULATION OF NITRIC OXIDE SYNTHASE ACTIVITY 2 49 0.00144 0.008896
752 POSITIVE REGULATION OF CHEMOKINE PRODUCTION 2 49 0.00144 0.008896
753 REGULATION OF STEROID BIOSYNTHETIC PROCESS 2 49 0.00144 0.008896
754 INTRACELLULAR SIGNAL TRANSDUCTION 7 1572 0.001457 0.008994
755 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 3 199 0.001484 0.009144
756 LYMPHOCYTE HOMEOSTASIS 2 50 0.001499 0.009187
757 REGULATION OF ADHERENS JUNCTION ORGANIZATION 2 50 0.001499 0.009187
758 RESPONSE TO PROGESTERONE 2 50 0.001499 0.009187
759 ENDODERM FORMATION 2 50 0.001499 0.009187
760 POSITIVE REGULATION OF FAT CELL DIFFERENTIATION 2 51 0.001559 0.009492
761 NEURAL CREST CELL MIGRATION 2 51 0.001559 0.009492
762 NEGATIVE REGULATION OF CHEMOTAXIS 2 51 0.001559 0.009492
763 REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 2 51 0.001559 0.009492
764 MECHANORECEPTOR DIFFERENTIATION 2 51 0.001559 0.009492
765 POSITIVE REGULATION OF REPRODUCTIVE PROCESS 2 52 0.00162 0.009801
766 NEGATIVE REGULATION OF RESPONSE TO DNA DAMAGE STIMULUS 2 52 0.00162 0.009801
767 REGULATION OF SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 3 205 0.001616 0.009801
768 INTERACTION WITH SYMBIONT 2 52 0.00162 0.009801
769 POSITIVE REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 2 52 0.00162 0.009801
NumGOOverlapSizeP ValueAdj. P Value
1 TRANSFORMING GROWTH FACTOR BETA RECEPTOR BINDING 6 50 1.749e-11 1.625e-08
2 RECEPTOR BINDING 12 1476 1.57e-08 7.293e-06
3 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 5 90 5.205e-08 1.612e-05
4 MACROMOLECULAR COMPLEX BINDING 11 1399 1.164e-07 2.703e-05
5 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 10 1199 3.221e-07 5.985e-05
6 CYTOKINE RECEPTOR BINDING 6 271 4.871e-07 7.542e-05
7 PROTEIN HETERODIMERIZATION ACTIVITY 7 468 6.509e-07 8.638e-05
8 SMAD BINDING 4 72 1.298e-06 0.000106
9 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 6 315 1.172e-06 0.000106
10 GROWTH FACTOR ACTIVITY 5 160 9.218e-07 0.000106
11 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 6 328 1.483e-06 0.000106
12 TRANSCRIPTION FACTOR BINDING 7 524 1.386e-06 0.000106
13 SEQUENCE SPECIFIC DNA BINDING 9 1037 1.105e-06 0.000106
14 PROTEIN DIMERIZATION ACTIVITY 9 1149 2.593e-06 0.0001721
15 CYTOKINE ACTIVITY 5 219 4.309e-06 0.0002669
16 PROTEIN KINASE ACTIVITY 7 640 5.213e-06 0.000269
17 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 7 629 4.651e-06 0.000269
18 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 5 226 5.024e-06 0.000269
19 CHROMATIN BINDING 6 435 7.542e-06 0.0003688
20 CORE PROMOTER BINDING 4 152 2.537e-05 0.001139
21 REGULATORY REGION NUCLEIC ACID BINDING 7 818 2.575e-05 0.001139
22 KINASE ACTIVITY 7 842 3.101e-05 0.001309
23 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 7 992 8.8e-05 0.003555
24 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 3 81 0.0001069 0.004138
25 BETA CATENIN BINDING 3 84 0.0001191 0.004217
26 C2H2 ZINC FINGER DOMAIN BINDING 2 14 0.0001142 0.004217
27 RECEPTOR SERINE THREONINE KINASE BINDING 2 15 0.0001316 0.004217
28 PROTEIN KINASE A CATALYTIC SUBUNIT BINDING 2 15 0.0001316 0.004217
29 PROTEIN SERINE THREONINE KINASE ACTIVITY 5 445 0.0001288 0.004217
30 TRANSFORMING GROWTH FACTOR BETA BINDING 2 16 0.0001503 0.004655
31 CYTOKINE BINDING 3 92 0.0001561 0.004677
32 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE ACTIVITY 2 17 0.0001703 0.004943
33 DNA BINDING BENDING 2 20 0.0002374 0.006682
34 FIBROBLAST GROWTH FACTOR BINDING 2 23 0.0003154 0.008618
35 GROWTH FACTOR BINDING 3 123 0.0003674 0.009752
NumGOOverlapSizeP ValueAdj. P Value
1 TRANSCRIPTION FACTOR COMPLEX 6 298 8.486e-07 0.0004956
2 EXTRACELLULAR MATRIX 6 426 6.692e-06 0.001954
3 CELL SURFACE 7 757 1.561e-05 0.002278
4 NUCLEAR TRANSCRIPTION FACTOR COMPLEX 4 127 1.25e-05 0.002278
5 PLATELET ALPHA GRANULE LUMEN 3 55 3.352e-05 0.003915
6 PLATELET ALPHA GRANULE 3 75 8.499e-05 0.007904
7 EXTRACELLULAR SPACE 8 1376 9.473e-05 0.007904
8 SECRETORY GRANULE LUMEN 3 85 0.0001234 0.009007

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04390_Hippo_signaling_pathway 9 154 5.601e-14 1.008e-11
2 hsa04350_TGF.beta_signaling_pathway 6 85 4.692e-10 4.223e-08
3 hsa04340_Hedgehog_signaling_pathway 4 56 4.691e-07 2.814e-05
4 hsa04520_Adherens_junction 3 73 7.84e-05 0.002824
5 hsa04144_Endocytosis 4 203 7.843e-05 0.002824
6 hsa04916_Melanogenesis 3 101 0.0002057 0.005873
7 hsa04010_MAPK_signaling_pathway 4 268 0.0002284 0.005873
8 hsa04110_Cell_cycle 3 128 0.0004129 0.008258
9 hsa04380_Osteoclast_differentiation 3 128 0.0004129 0.008258
10 hsa04310_Wnt_signaling_pathway 3 151 0.0006687 0.01204
11 hsa04330_Notch_signaling_pathway 2 47 0.001325 0.02168
12 hsa04151_PI3K_AKT_signaling_pathway 3 351 0.007315 0.1097
13 hsa04510_Focal_adhesion 2 200 0.02193 0.3037
14 hsa04014_Ras_signaling_pathway 2 236 0.02981 0.3577

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

PCA3

 hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-185-3p;hsa-miR-18a-3p;hsa-miR-18a-5p;hsa-miR-193b-3p;hsa-miR-21-5p;hsa-miR-222-5p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-296-5p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-944 18 TGFBR3 Sponge network -2.778 8.0E-5 -2.545 0 0.424
2 FAM95B1 hsa-miR-16-2-3p;hsa-miR-18a-3p;hsa-miR-193b-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-323b-3p;hsa-miR-424-5p;hsa-miR-455-5p;hsa-miR-484;hsa-miR-944 10 TGFBR3 Sponge network -1.726 0.00466 -2.545 0 0.287

Quest ID: 8464b0604102667906ce6089a644c8be