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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-192-3p ACTB -0.64 0.00027 -0.06 0.43313 MirTarget -0.11 0 NA
2 hsa-miR-92a-3p ACTB 0.21 0.13429 -0.06 0.43313 miRNAWalker2 validate -0.1 6.0E-5 NA
3 hsa-miR-148a-5p ACTG1 -0.77 0 -0.12 0.20938 MirTarget; miRNATAP -0.17 0 NA
4 hsa-miR-193b-3p ACTG1 -0.17 0.27202 -0.12 0.20938 miRNAWalker2 validate -0.18 0 NA
5 hsa-miR-103a-3p AMOT 0.77 0 -0.9 0.00079 MirTarget -0.45 0.00011 NA
6 hsa-miR-107 AMOT 0.24 0.01708 -0.9 0.00079 MirTarget; PITA; miRanda; miRNATAP -0.41 0.00177 NA
7 hsa-miR-10b-3p AMOT 2.77 0 -0.9 0.00079 mirMAP -0.14 0.00214 NA
8 hsa-miR-16-1-3p AMOT 0.39 0.00112 -0.9 0.00079 mirMAP -0.31 0.00493 NA
9 hsa-miR-221-3p AMOT 1.12 0 -0.9 0.00079 miRNAWalker2 validate -0.32 9.0E-5 NA
10 hsa-miR-30d-5p AMOT 0.72 0 -0.9 0.00079 mirMAP -0.3 0.00241 NA
11 hsa-miR-330-5p AMOT 0.44 0.00533 -0.9 0.00079 miRanda -0.28 0.00054 NA
12 hsa-miR-362-3p AMOT 0.81 0 -0.9 0.00079 miRanda -0.29 0.00208 NA
13 hsa-miR-500a-5p AMOT 0.8 0 -0.9 0.00079 mirMAP -0.29 0.00067 NA
14 hsa-miR-501-5p AMOT 1.15 0 -0.9 0.00079 miRNATAP -0.29 3.0E-5 NA
15 hsa-miR-532-5p AMOT 1.03 0 -0.9 0.00079 MirTarget -0.37 0.00017 NA
16 hsa-miR-618 AMOT 0.14 0.51715 -0.9 0.00079 mirMAP -0.18 0.00497 NA
17 hsa-miR-766-3p AMOT 0.2 0.25723 -0.9 0.00079 MirTarget -0.36 0 NA
18 hsa-miR-106b-5p APC 0.65 0 -0.18 0.06792 miRNAWalker2 validate; miRTarBase -0.15 0.00024 23087084 miR 106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma; Moreover we demonstrated that miR-106b downregulates APC expression by directly targeting the 3'-untranslated region of APC messenger RNA; Taken together our results suggest that miR-106b plays an important role in promoting the proliferation of human hepatoma cells and presents a novel mechanism of micro RNA-mediated direct suppression of APC expression in cancer cells
19 hsa-miR-21-5p APC 1.51 0 -0.18 0.06792 miRNAWalker2 validate -0.17 0 23773491; 24832083 The prognostic significance of APC gene mutation and miR 21 expression in advanced stage colorectal cancer; The aim of this study was to analyse the association of APC gene mutation and miR-21 expression with clinical outcome in CRC patients; APC gene mutation and expression of APC and miR-21 were analysed by direct DNA sequencing and real-time reverse transcription polymerase chain reaction; APC gene expression was low in CRC and negatively correlated with miR-21 expression and gene mutation; In Taiwan downregulation of the APC gene in CRC correlated with gene mutation and miR-21 upregulation; APC mutation and miR-21 expression could be used to predict the clinical outcome of CRC especially in patients with advanced disease;MicroRNA 21 promotes tumour malignancy via increased nuclear translocation of β catenin and predicts poor outcome in APC mutated but not in APC wild type colorectal cancer; However in our preliminary data the prognostic value of miR-21 levels was observed only in adenomatous polyposis coli APC-mutated tumours not in APC-wild-type tumours; We enrolled 165 colorectal tumour to determine APC mutation miR-21 levels and nuclear β-catenin expression by direct sequencing real-time PCR and immunohistochemistry
20 hsa-let-7a-5p APC2 -0.33 0.00046 1.72 0 TargetScan -0.3 0.00538 NA
21 hsa-miR-125a-5p APC2 -0.91 0 1.72 0 mirMAP -0.2 0.0003 NA
22 hsa-miR-194-3p APC2 -0.77 3.0E-5 1.72 0 mirMAP -0.17 0.00111 NA
23 hsa-miR-199a-5p APC2 -1.99 0 1.72 0 mirMAP -0.1 0.00178 NA
24 hsa-miR-20a-3p APC2 -0.32 0.04679 1.72 0 mirMAP -0.25 7.0E-5 NA
25 hsa-miR-23b-5p APC2 -1.05 0 1.72 0 mirMAP -0.22 0.0013 NA
26 hsa-miR-28-5p APC2 -0.43 0 1.72 0 mirMAP -0.3 0.00527 NA
27 hsa-miR-505-5p APC2 -0.77 1.0E-5 1.72 0 mirMAP -0.15 0.00924 NA
28 hsa-miR-107 AREG 0.24 0.01708 -1.67 0 miRanda -1.2 0 NA
29 hsa-miR-320a AXIN1 0.33 0.02214 0.3 0.00968 miRNAWalker2 validate -0.1 0.00946 NA
30 hsa-miR-15b-5p AXIN2 0.23 0.08248 0.11 0.75298 miRTarBase; MirTarget; miRNATAP -0.45 0.00081 NA
31 hsa-miR-16-2-3p AXIN2 -0.03 0.80516 0.11 0.75298 mirMAP -0.64 0 NA
32 hsa-miR-16-5p AXIN2 -0.4 0.0001 0.11 0.75298 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.49 0.00421 NA
33 hsa-miR-195-3p AXIN2 -1.09 0 0.11 0.75298 mirMAP -0.31 0.00083 NA
34 hsa-miR-195-5p AXIN2 -1.86 0 0.11 0.75298 MirTarget; miRNATAP -0.25 0.00506 NA
35 hsa-miR-26b-3p AXIN2 -1.26 0 0.11 0.75298 MirTarget -0.59 3.0E-5 NA
36 hsa-miR-326 AXIN2 -1.88 0 0.11 0.75298 miRanda -0.36 2.0E-5 NA
37 hsa-miR-338-5p AXIN2 -0.22 0.25239 0.11 0.75298 miRNATAP -0.34 0.00017 NA
38 hsa-miR-497-5p AXIN2 -1.41 0 0.11 0.75298 MirTarget; miRNATAP -0.29 0.00329 NA
39 hsa-miR-616-3p AXIN2 -0.7 2.0E-5 0.11 0.75298 MirTarget -0.42 8.0E-5 NA
40 hsa-let-7a-2-3p BBC3 -1.19 0 0.8 0 MirTarget -0.19 0 NA
41 hsa-let-7g-3p BBC3 -1.14 0 0.8 0 MirTarget; miRNATAP -0.18 0.0001 NA
42 hsa-miR-101-3p BBC3 -1.48 0 0.8 0 miRNATAP -0.32 0 NA
43 hsa-miR-125b-5p BBC3 -1.36 0 0.8 0 miRNAWalker2 validate; miRTarBase -0.25 0 25184537 Thus far two of these target genes BBC3 and NEU1 that are tumor suppressor genes but not yet studied in PDAC appear to be functional targets of miR-125b since knockdown of miR125b caused their up regulation
44 hsa-miR-139-5p BBC3 -2.11 0 0.8 0 miRNATAP -0.23 0 NA
45 hsa-miR-140-5p BBC3 -0.22 0.01407 0.8 0 miRNATAP -0.25 0.0003 NA
46 hsa-miR-144-3p BBC3 -2.98 0 0.8 0 miRNATAP -0.11 0 NA
47 hsa-miR-27b-3p BBC3 -0.82 0 0.8 0 miRNATAP -0.2 0.00022 NA
48 hsa-miR-345-5p BBC3 -0.71 0 0.8 0 miRNATAP -0.17 4.0E-5 NA
49 hsa-miR-590-3p BBC3 -0.47 2.0E-5 0.8 0 miRanda -0.25 1.0E-5 NA
50 hsa-let-7b-5p BIRC5 -0.96 0 4.5 0 miRNAWalker2 validate -0.71 0 NA
51 hsa-miR-101-3p BIRC5 -1.48 0 4.5 0 miRNAWalker2 validate -1.33 0 NA
52 hsa-miR-10a-5p BIRC5 -1.48 0 4.5 0 miRNAWalker2 validate -0.71 0 NA
53 hsa-miR-203a-3p BIRC5 -1.34 9.0E-5 4.5 0 miRTarBase -0.13 0.00935 22713668; 27714672 Luciferase assays were also performed to validate BIRC5 and LASP1 as miR-203 targets; Both miR-203 and BIRC5 siRNA signicantly inhibited cell proliferation in TNBC cells; Moreover up-regulated of BIRC5 and LASP1 was able to abrogate the effects induced by transfection with the miR-203 precursor;miR 203 is a predictive biomarker for colorectal cancer and its expression is associated with BIRC5; The purpose of this study was to explore the role of miR-203 in colorectal cancer CRC and evaluate the correlation between miR-203 and BIRC5; Finally miR-203 expression was negatively associated with that of BIRC5 r = -0.8150 P < 0.05
54 hsa-miR-30c-5p BIRC5 -0.43 0.00016 4.5 0 miRNAWalker2 validate -0.45 0.00191 NA
55 hsa-miR-335-5p BIRC5 -1.61 0 4.5 0 miRNAWalker2 validate; MirTarget -0.5 0 23232114 Genetic variation in a miR 335 binding site in BIRC5 alters susceptibility to lung cancer in Chinese Han populations; In support of the postulation that the 3' UTR SNP may directly affect miRNA-binding site reporter gene assays indicated BIRC5 was a direct target of miR-335 and the rs2239680 T>C change resulted in altered regulation of BIRC5 expression; Our findings defined a 3' UTR SNP in human BIRC5 oncogene that may increase individual susceptibility to lung cancer probably by attenuating the interaction between miR-335 and BIRC5
56 hsa-miR-542-3p BIRC5 -1.31 0 4.5 0 miRNAWalker2 validate; MirTarget; miRanda -0.82 0 NA
57 hsa-miR-142-3p BMP4 -1.42 0 0.76 0.00257 PITA; miRanda -0.21 0.00115 NA
58 hsa-miR-130b-3p BMP6 0.69 0.00011 -1.04 0 MirTarget -0.26 0 NA
59 hsa-miR-362-3p BMP6 0.81 0 -1.04 0 miRanda -0.3 4.0E-5 NA
60 hsa-miR-454-3p BMP6 0.67 0 -1.04 0 MirTarget -0.22 0.00157 NA
61 hsa-miR-130b-5p BMP7 0.17 0.33761 0.83 0.04887 mirMAP -0.32 0.00583 NA
62 hsa-miR-1976 BMP7 -0.43 0.00325 0.83 0.04887 MirTarget -0.45 0.00115 NA
63 hsa-miR-22-3p BMP7 -0.63 0 0.83 0.04887 miRNAWalker2 validate; miRTarBase -0.87 1.0E-5 NA
64 hsa-miR-30a-5p BMP7 -0.63 0.00011 0.83 0.04887 mirMAP; miRNATAP -0.35 0.00579 NA
65 hsa-miR-30e-5p BMP7 -0.63 0 0.83 0.04887 mirMAP -0.58 0.00444 NA
66 hsa-miR-34a-5p BMP7 1.04 0 0.83 0.04887 miRNAWalker2 validate -0.45 0.00162 NA
67 hsa-miR-616-5p BMP7 0.15 0.40284 0.83 0.04887 mirMAP -0.33 0.0036 NA
68 hsa-miR-194-3p BMP8A -0.77 3.0E-5 1.39 0 MirTarget -0.35 0 NA
69 hsa-miR-30b-3p BMP8A -0.44 0.00095 1.39 0 MirTarget -0.25 0.00222 NA
70 hsa-miR-30e-3p BMP8A -1.21 0 1.39 0 MirTarget -0.32 0.00032 NA
71 hsa-miR-455-5p BMP8A -0.27 0.05813 1.39 0 MirTarget; miRanda -0.22 0.00398 NA
72 hsa-miR-618 BMP8B 0.14 0.51715 0.28 0.41783 mirMAP -0.24 0.00328 NA
73 hsa-miR-140-5p BMPR1A -0.22 0.01407 0.07 0.48504 miRanda -0.15 0.00409 NA
74 hsa-miR-130b-3p BMPR1B 0.69 0.00011 -3.31 0 miRNATAP -0.34 0.00049 NA
75 hsa-miR-140-3p BMPR1B 0.55 0 -3.31 0 MirTarget -1.09 0 NA
76 hsa-miR-362-3p BMPR1B 0.81 0 -3.31 0 MirTarget; miRanda -0.65 0 NA
77 hsa-miR-374a-5p BMPR1B 0.02 0.86978 -3.31 0 MirTarget -0.96 0 NA
78 hsa-miR-374b-5p BMPR1B -0.31 0.00301 -3.31 0 MirTarget -0.45 0.00882 NA
79 hsa-miR-106b-5p BMPR2 0.65 0 -0.74 0 MirTarget; miRNATAP -0.22 0 NA
80 hsa-miR-130b-3p BMPR2 0.69 0.00011 -0.74 0 MirTarget; miRNATAP -0.12 2.0E-5 NA
81 hsa-miR-148b-3p BMPR2 0.27 0.00185 -0.74 0 mirMAP -0.27 1.0E-5 NA
82 hsa-miR-17-5p BMPR2 0.7 2.0E-5 -0.74 0 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.26 0 NA
83 hsa-miR-185-5p BMPR2 0.48 0 -0.74 0 MirTarget -0.25 0 NA
84 hsa-miR-19a-3p BMPR2 1.02 0 -0.74 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.17 0 NA
85 hsa-miR-19b-3p BMPR2 0.6 0.00017 -0.74 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.21 0 NA
86 hsa-miR-20a-5p BMPR2 0.85 0 -0.74 0 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.24 0 NA
87 hsa-miR-21-5p BMPR2 1.51 0 -0.74 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.28 0 NA
88 hsa-miR-25-3p BMPR2 0.63 0 -0.74 0 miRNATAP -0.17 0.00117 NA
89 hsa-miR-29a-5p BMPR2 -0.11 0.34962 -0.74 0 mirMAP -0.15 0.00063 NA
90 hsa-miR-301a-3p BMPR2 0.84 0 -0.74 0 MirTarget; miRNATAP -0.11 0.00019 NA
91 hsa-miR-30d-5p BMPR2 0.72 0 -0.74 0 mirMAP -0.19 0 NA
92 hsa-miR-362-3p BMPR2 0.81 0 -0.74 0 MirTarget; PITA; miRanda; miRNATAP -0.18 0 NA
93 hsa-miR-455-5p BMPR2 -0.27 0.05813 -0.74 0 PITA -0.13 0.00044 NA
94 hsa-miR-532-5p BMPR2 1.03 0 -0.74 0 PITA -0.29 0 NA
95 hsa-miR-590-5p BMPR2 -0.1 0.31003 -0.74 0 MirTarget; PITA; miRNATAP -0.19 0.0002 NA
96 hsa-miR-618 BMPR2 0.14 0.51715 -0.74 0 PITA; mirMAP -0.1 5.0E-5 NA
97 hsa-miR-671-5p BMPR2 0.84 0 -0.74 0 miRNATAP -0.11 0.00171 NA
98 hsa-miR-769-5p BMPR2 0.22 0.03334 -0.74 0 miRNATAP -0.15 0.003 NA
99 hsa-miR-877-5p BMPR2 1.36 0 -0.74 0 MirTarget -0.15 0 NA
100 hsa-miR-92a-3p BMPR2 0.21 0.13429 -0.74 0 miRNAWalker2 validate; miRNATAP -0.24 0 NA
101 hsa-miR-93-3p BMPR2 0.4 0.00131 -0.74 0 miRNAWalker2 validate -0.19 0 NA
102 hsa-miR-93-5p BMPR2 1.4 0 -0.74 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.27 0 NA
103 hsa-miR-15b-5p BTRC 0.23 0.08248 -0 0.97671 MirTarget; miRNATAP -0.12 0 NA
104 hsa-miR-16-5p BTRC -0.4 0.0001 -0 0.97671 miRNAWalker2 validate; MirTarget; miRNATAP -0.17 0 NA
105 hsa-miR-193a-3p BTRC -0.12 0.30939 -0 0.97671 MirTarget; miRanda -0.15 0 NA
106 hsa-miR-193b-3p BTRC -0.17 0.27202 -0 0.97671 miRNAWalker2 validate -0.16 0 NA
107 hsa-miR-361-3p BTRC 0.28 0.00549 -0 0.97671 MirTarget; PITA; miRNATAP -0.1 0.00495 NA
108 hsa-miR-497-5p BTRC -1.41 0 -0 0.97671 MirTarget; miRNATAP -0.11 0 NA
109 hsa-miR-505-3p BTRC -1.2 0 -0 0.97671 MirTarget -0.13 0 NA
110 hsa-miR-106a-5p CCND1 -0.46 0.00972 -0.9 1.0E-5 MirTarget; miRNATAP -0.26 0 NA
111 hsa-miR-106b-5p CCND1 0.65 0 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.43 0 NA
112 hsa-miR-1266-5p CCND1 1.63 0 -0.9 1.0E-5 MirTarget -0.23 0 NA
113 hsa-miR-15b-5p CCND1 0.23 0.08248 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.54 0 NA
114 hsa-miR-16-5p CCND1 -0.4 0.0001 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.31 0.00178 23991964; 22922827; 18483394 At the molecular level our results further revealed that cyclin D1 expression was negatively regulated by miR-16;CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL
115 hsa-miR-17-5p CCND1 0.7 2.0E-5 -0.9 1.0E-5 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.34 0 26431674 Bioinformatics Prediction and In Vitro Analysis Revealed That miR 17 Targets Cyclin D1 mRNA in Triple Negative Breast Cancer Cells; In this study using bioinformatic analyses miR-17 was selected as it targets the 3'UTR of CCND1 gene with the highest score; After lentiviral transduction of miR-17 to the target cells gene expression analysis showed decreased expression of CCND1 gene
116 hsa-miR-186-5p CCND1 -0.06 0.53529 -0.9 1.0E-5 mirMAP -0.32 0.00286 NA
117 hsa-miR-19a-3p CCND1 1.02 0 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; miRNATAP -0.28 0 25985117 Moreover miR-19a might play inhibitory roles in HCC malignancy via regulating Cyclin D1 expression
118 hsa-miR-19b-1-5p CCND1 -0.28 0.07831 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase -0.31 0 NA
119 hsa-miR-19b-3p CCND1 0.6 0.00017 -0.9 1.0E-5 miRNATAP -0.34 0 NA
120 hsa-miR-20a-5p CCND1 0.85 0 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.33 0 NA
121 hsa-miR-20b-5p CCND1 0.46 0.02859 -0.9 1.0E-5 MirTarget; miRNATAP -0.23 0 NA
122 hsa-miR-340-5p CCND1 -0 0.9685 -0.9 1.0E-5 mirMAP -0.32 0.00013 NA
123 hsa-miR-425-5p CCND1 0.59 2.0E-5 -0.9 1.0E-5 miRNAWalker2 validate -0.39 0 NA
124 hsa-miR-503-5p CCND1 0.19 0.26842 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget -0.16 0.00815 26047605; 23731275 MiR 503 inhibited cell proliferation of human breast cancer cells by suppressing CCND1 expression; Overexpression of miR-503 in breast cancer cell lines reduced cell proliferation through inducing G0/G1 cell cycle arrest by targeting CCND1;MicroRNA 503 suppresses proliferation and cell cycle progression of endometrioid endometrial cancer by negatively regulating cyclin D1; CCND1 has a binding sequence of miR-503 within its 3' untranslated region and was confirmed to be a direct target of miR-503 by the fluorescent reporter assays; Increasing the miR-503 level in EEC cells suppressed cell viability colon formation activity and cell-cycle progression and the inhibited oncogenic phenotypes induced by miR-503 were alleviated by ectopic expression of CCND1 without the untranslated region sequence; Collectively this study suggested that miR-503 plays a tumor-suppressor role by targeting CCND1; Abnormal suppression of miR-503 leads to an increase in the CCND1 level which may promote carcinogenesis and progression of EEC
125 hsa-miR-589-3p CCND1 1.17 0 -0.9 1.0E-5 MirTarget -0.18 0.00124 NA
126 hsa-miR-616-5p CCND1 0.15 0.40284 -0.9 1.0E-5 mirMAP -0.26 1.0E-5 NA
127 hsa-miR-7-1-3p CCND1 -0.57 2.0E-5 -0.9 1.0E-5 mirMAP -0.26 0.00057 NA
128 hsa-miR-9-5p CCND1 1.26 9.0E-5 -0.9 1.0E-5 miRNAWalker2 validate -0.14 1.0E-5 NA
129 hsa-miR-92a-3p CCND1 0.21 0.13429 -0.9 1.0E-5 miRNAWalker2 validate -0.41 0 NA
130 hsa-miR-93-5p CCND1 1.4 0 -0.9 1.0E-5 miRNAWalker2 validate; MirTarget; miRNATAP -0.34 0 NA
131 hsa-miR-942-5p CCND1 0.35 0.02833 -0.9 1.0E-5 MirTarget -0.25 0.00012 NA
132 hsa-miR-130b-5p CCND2 0.17 0.33761 0.36 0.03656 mirMAP -0.17 0.00018 NA
133 hsa-miR-20a-5p CCND2 0.85 0 0.36 0.03656 miRNAWalker2 validate; miRTarBase; miRNATAP -0.16 0.00121 NA
134 hsa-miR-28-5p CCND2 -0.43 0 0.36 0.03656 miRanda -0.48 0 NA
135 hsa-miR-33a-3p CCND2 -0.68 1.0E-5 0.36 0.03656 MirTarget -0.26 0 NA
136 hsa-miR-3607-3p CCND2 -2.16 0 0.36 0.03656 mirMAP -0.12 0.0007 NA
137 hsa-miR-378a-3p CCND2 -1.19 0 0.36 0.03656 miRNAWalker2 validate -0.18 2.0E-5 NA
138 hsa-miR-548v CCND2 -0.27 0.17626 0.36 0.03656 MirTarget -0.15 0.00034 NA
139 hsa-miR-616-5p CCND2 0.15 0.40284 0.36 0.03656 mirMAP -0.32 0 NA
140 hsa-miR-618 CCND2 0.14 0.51715 0.36 0.03656 mirMAP -0.23 0 NA
141 hsa-miR-27b-3p CCND3 -0.82 0 0.08 0.47843 miRNAWalker2 validate -0.24 0 NA
142 hsa-miR-320a CCND3 0.33 0.02214 0.08 0.47843 miRanda -0.12 0.00135 NA
143 hsa-miR-146b-5p CDH1 0.42 0.04574 -0.93 4.0E-5 miRanda -0.21 6.0E-5 NA
144 hsa-miR-185-5p CDH1 0.48 0 -0.93 4.0E-5 MirTarget -0.45 8.0E-5 27212161; 24025511 We also found that ectopic expression of miR-185 reversed EMT via the up-regulation of E-cadherin and down-regulation of vimentin in epithelial and mesenchymal HCC cells;After transfection of miR-185 inhibitor into KYSE30 the expression of E-cadherin a downstream protein of Six1 was observed under confocal microscope; After transfection of miR-185 inhibitorthe expression level of E-cadherin decreased
145 hsa-let-7b-5p CSNK1D -0.96 0 0.47 0 miRNAWalker2 validate -0.19 0 NA
146 hsa-miR-29a-3p CSNK1D -0.86 0 0.47 0 mirMAP -0.14 0 NA
147 hsa-miR-29c-3p CSNK1D -1.44 0 0.47 0 mirMAP -0.15 0 NA
148 hsa-miR-148a-5p CSNK1E -0.77 0 0.61 0 miRNATAP -0.25 0 NA
149 hsa-miR-195-3p CSNK1E -1.09 0 0.61 0 miRNATAP -0.1 1.0E-5 NA
150 hsa-miR-140-5p CTNNA1 -0.22 0.01407 0.48 0 miRanda -0.1 0.00712 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 CANONICAL WNT SIGNALING PATHWAY 31 95 2.596e-46 1.208e-42
2 WNT SIGNALING PATHWAY 42 351 4.268e-43 9.93e-40
3 EPITHELIUM DEVELOPMENT 56 945 1.584e-41 2.457e-38
4 ORGAN MORPHOGENESIS 53 841 2.025e-40 2.356e-37
5 TISSUE MORPHOGENESIS 45 533 1.958e-39 1.822e-36
6 TISSUE DEVELOPMENT 63 1518 3.754e-38 2.911e-35
7 REGULATION OF WNT SIGNALING PATHWAY 37 310 9.888e-38 6.573e-35
8 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 33 236 6.579e-36 3.827e-33
9 NEUROGENESIS 59 1402 1.191e-35 6.156e-33
10 REGULATION OF PHOSPHORUS METABOLIC PROCESS 61 1618 2.462e-34 1.145e-31
11 REGULATION OF PROTEIN MODIFICATION PROCESS 62 1710 5.021e-34 2.124e-31
12 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 61 1672 1.587e-33 6.154e-31
13 TUBE DEVELOPMENT 41 552 1.774e-33 6.348e-31
14 POSITIVE REGULATION OF RESPONSE TO STIMULUS 64 1929 4.617e-33 1.534e-30
15 MORPHOGENESIS OF AN EPITHELIUM 36 400 3.279e-32 1.017e-29
16 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 49 1021 1.646e-31 4.788e-29
17 POSITIVE REGULATION OF CELL COMMUNICATION 57 1532 2.071e-31 5.668e-29
18 EMBRYONIC MORPHOGENESIS 39 539 2.469e-31 6.381e-29
19 REGULATION OF CELL DIFFERENTIATION 56 1492 5.69e-31 1.393e-28
20 REGULATION OF CELLULAR PROTEIN LOCALIZATION 39 552 6.129e-31 1.426e-28
21 NEGATIVE REGULATION OF CELL COMMUNICATION 51 1192 1.536e-30 3.404e-28
22 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 50 1142 2.42e-30 5.118e-28
23 POSITIVE REGULATION OF CELL DIFFERENTIATION 44 823 5.505e-30 1.114e-27
24 TUBE MORPHOGENESIS 32 323 6.727e-30 1.304e-27
25 REGULATION OF ORGAN MORPHOGENESIS 29 242 1.645e-29 3.061e-27
26 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 54 1492 6.374e-29 1.141e-26
27 NEURON DIFFERENTIATION 44 874 6.787e-29 1.17e-26
28 CELL DEVELOPMENT 53 1426 7.101e-29 1.18e-26
29 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 52 1360 7.528e-29 1.208e-26
30 RESPONSE TO GROWTH FACTOR 35 475 2.757e-28 4.277e-26
31 SENSORY ORGAN DEVELOPMENT 35 493 9.836e-28 1.476e-25
32 POSITIVE REGULATION OF GENE EXPRESSION 56 1733 1.236e-27 1.798e-25
33 HIPPO SIGNALING 15 27 4.042e-27 5.699e-25
34 REGULATION OF PROTEIN LOCALIZATION 43 950 2.511e-26 3.437e-24
35 EMBRYO DEVELOPMENT 42 894 2.616e-26 3.478e-24
36 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 46 1135 2.942e-26 3.803e-24
37 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 25 197 4.185e-26 5.263e-24
38 CELL FATE COMMITMENT 26 227 5.976e-26 7.317e-24
39 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 44 1036 7.507e-26 8.732e-24
40 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 44 1036 7.507e-26 8.732e-24
41 REGULATION OF CELL DEATH 50 1472 2.902e-25 3.294e-23
42 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 23 162 3.255e-25 3.606e-23
43 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 42 957 3.769e-25 4.078e-23
44 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 54 1805 7.096e-25 7.504e-23
45 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 54 1848 2.202e-24 2.277e-22
46 REGULATION OF CELLULAR LOCALIZATION 46 1277 4.219e-24 4.267e-22
47 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 38 801 7.883e-24 7.804e-22
48 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 33 554 1.088e-23 1.055e-21
49 REGULATION OF CELL DEVELOPMENT 38 836 3.583e-23 3.402e-21
50 REGULATION OF CELL PROLIFERATION 48 1496 4.472e-23 4.162e-21
51 EMBRYONIC ORGAN DEVELOPMENT 29 406 5.265e-23 4.803e-21
52 GROWTH 29 410 6.939e-23 6.209e-21
53 HEAD DEVELOPMENT 35 709 1.877e-22 1.648e-20
54 REGULATION OF EMBRYONIC DEVELOPMENT 19 114 2.434e-22 2.097e-20
55 POSITIVE REGULATION OF CELL DEVELOPMENT 30 472 2.5e-22 2.115e-20
56 CELL PROLIFERATION 34 672 3.88e-22 3.167e-20
57 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 22 190 3.875e-22 3.167e-20
58 BETA CATENIN DESTRUCTION COMPLEX DISASSEMBLY 12 22 9.359e-22 7.508e-20
59 POSITIVE REGULATION OF CELL DEATH 32 605 2.138e-21 1.686e-19
60 REGULATION OF OSSIFICATION 21 178 2.452e-21 1.902e-19
61 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 39 1008 2.675e-21 2.041e-19
62 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 30 513 2.725e-21 2.045e-19
63 GASTRULATION 20 155 3.741e-21 2.763e-19
64 CARDIOVASCULAR SYSTEM DEVELOPMENT 35 788 5.84e-21 4.18e-19
65 CIRCULATORY SYSTEM DEVELOPMENT 35 788 5.84e-21 4.18e-19
66 GLAND DEVELOPMENT 27 395 6.253e-21 4.408e-19
67 REGULATION OF STEM CELL DIFFERENTIATION 18 113 7.769e-21 5.395e-19
68 NON CANONICAL WNT SIGNALING PATHWAY 19 140 1.446e-20 9.896e-19
69 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 14 50 3.573e-20 2.409e-18
70 CARTILAGE DEVELOPMENT 19 147 3.763e-20 2.501e-18
71 CELLULAR COMPONENT MORPHOGENESIS 36 900 4.5e-20 2.949e-18
72 REGULATION OF INTRACELLULAR TRANSPORT 31 621 5.411e-20 3.497e-18
73 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 43 1395 8.293e-20 5.286e-18
74 EMBRYONIC ORGAN MORPHOGENESIS 23 279 1.014e-19 6.374e-18
75 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 18 131 1.249e-19 7.749e-18
76 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 21 218 1.798e-19 1.101e-17
77 SMAD PROTEIN SIGNAL TRANSDUCTION 14 56 2.145e-19 1.296e-17
78 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 21 220 2.178e-19 1.299e-17
79 REGULATION OF OSTEOBLAST DIFFERENTIATION 17 112 2.348e-19 1.383e-17
80 REGULATION OF MAPK CASCADE 31 660 3.134e-19 1.823e-17
81 RESPONSE TO ENDOGENOUS STIMULUS 43 1450 3.571e-19 2.038e-17
82 CONNECTIVE TISSUE DEVELOPMENT 20 194 3.591e-19 2.038e-17
83 MORPHOGENESIS OF A BRANCHING STRUCTURE 19 167 4.477e-19 2.51e-17
84 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 18 141 4.892e-19 2.71e-17
85 MAMMARY GLAND DEVELOPMENT 17 117 5.097e-19 2.79e-17
86 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 14 60 6.282e-19 3.399e-17
87 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 12 34 7.466e-19 3.993e-17
88 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 20 207 1.317e-18 6.962e-17
89 REGULATION OF CARTILAGE DEVELOPMENT 14 63 1.334e-18 6.973e-17
90 POSITIVE REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 13 48 1.354e-18 6.999e-17
91 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 38 1152 2.284e-18 1.168e-16
92 REGULATION OF PROTEIN IMPORT 19 183 2.591e-18 1.296e-16
93 POSITIVE REGULATION OF OSSIFICATION 15 84 2.584e-18 1.296e-16
94 SKELETAL SYSTEM DEVELOPMENT 26 455 3.111e-18 1.54e-16
95 CELL JUNCTION ORGANIZATION 19 185 3.189e-18 1.562e-16
96 EYE DEVELOPMENT 23 326 3.331e-18 1.598e-16
97 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 46 1784 3.331e-18 1.598e-16
98 NEGATIVE REGULATION OF CELL DIFFERENTIATION 29 609 3.737e-18 1.774e-16
99 MESENCHYME DEVELOPMENT 19 190 5.3e-18 2.491e-16
100 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 35 983 6.611e-18 3.076e-16
101 CENTRAL NERVOUS SYSTEM DEVELOPMENT 33 872 1.192e-17 5.492e-16
102 REGULATION OF TRANSFERASE ACTIVITY 34 946 1.651e-17 7.531e-16
103 EPITHELIAL CELL DIFFERENTIATION 26 495 2.445e-17 1.104e-15
104 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 23 360 2.99e-17 1.338e-15
105 REGULATION OF KINASE ACTIVITY 31 776 3.114e-17 1.38e-15
106 REGULATION OF APOPTOTIC SIGNALING PATHWAY 23 363 3.588e-17 1.575e-15
107 PATTERN SPECIFICATION PROCESS 24 418 6.463e-17 2.811e-15
108 HEART DEVELOPMENT 25 466 6.638e-17 2.86e-15
109 DEVELOPMENTAL GROWTH 22 333 7.759e-17 3.312e-15
110 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 30 750 1.076e-16 4.551e-15
111 UROGENITAL SYSTEM DEVELOPMENT 21 299 1.215e-16 5.093e-15
112 MESODERM MORPHOGENESIS 13 66 1.309e-16 5.44e-15
113 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 16 134 1.488e-16 6.128e-15
114 NEGATIVE REGULATION OF CELL PROLIFERATION 28 643 1.554e-16 6.345e-15
115 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 13 67 1.616e-16 6.54e-15
116 FORMATION OF PRIMARY GERM LAYER 15 110 1.799e-16 7.218e-15
117 RESPIRATORY SYSTEM DEVELOPMENT 18 197 2.125e-16 8.452e-15
118 MAMMARY GLAND EPITHELIUM DEVELOPMENT 12 53 3.297e-16 1.3e-14
119 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 17 171 3.675e-16 1.437e-14
120 SENSORY ORGAN MORPHOGENESIS 19 239 3.958e-16 1.535e-14
121 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 16 144 4.788e-16 1.841e-14
122 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 40 1517 5.341e-16 1.988e-14
123 RESPONSE TO BMP 14 94 5.314e-16 1.988e-14
124 CELLULAR RESPONSE TO BMP STIMULUS 14 94 5.314e-16 1.988e-14
125 MESODERM DEVELOPMENT 15 118 5.317e-16 1.988e-14
126 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 25 514 6.516e-16 2.406e-14
127 REGULATION OF EPITHELIAL CELL PROLIFERATION 20 285 7.013e-16 2.57e-14
128 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 33 1004 7.464e-16 2.713e-14
129 HEART MORPHOGENESIS 18 212 7.834e-16 2.826e-14
130 OSSIFICATION 19 251 9.808e-16 3.51e-14
131 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 14 100 1.307e-15 4.642e-14
132 STEM CELL DIFFERENTIATION 17 190 2.181e-15 7.688e-14
133 REGULATION OF PROTEIN TARGETING 20 307 2.927e-15 1.024e-13
134 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 16 162 3.181e-15 1.104e-13
135 MESENCHYMAL CELL DIFFERENTIATION 15 134 3.707e-15 1.278e-13
136 NEGATIVE REGULATION OF GROWTH 18 236 5.178e-15 1.771e-13
137 LENS DEVELOPMENT IN CAMERA TYPE EYE 12 66 5.694e-15 1.934e-13
138 REGULATION OF TRANSPORT 42 1804 6.146e-15 2.072e-13
139 REGULATION OF STEM CELL PROLIFERATION 13 88 6.875e-15 2.301e-13
140 CELLULAR MACROMOLECULE LOCALIZATION 35 1234 7.004e-15 2.328e-13
141 MIDBRAIN DEVELOPMENT 13 90 9.314e-15 3.052e-13
142 MESONEPHROS DEVELOPMENT 13 90 9.314e-15 3.052e-13
143 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 23 470 9.597e-15 3.123e-13
144 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 40 1656 1.02e-14 3.296e-13
145 NEGATIVE REGULATION OF GENE EXPRESSION 38 1493 1.13e-14 3.627e-13
146 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 21 381 1.545e-14 4.925e-13
147 NEURAL TUBE DEVELOPMENT 15 149 1.837e-14 5.815e-13
148 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 10 38 2.006e-14 6.264e-13
149 MESENCHYME MORPHOGENESIS 10 38 2.006e-14 6.264e-13
150 PROTEIN COMPLEX SUBUNIT ORGANIZATION 38 1527 2.314e-14 7.18e-13
151 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 15 152 2.477e-14 7.632e-13
152 GLAND MORPHOGENESIS 13 97 2.549e-14 7.804e-13
153 POSITIVE REGULATION OF MOLECULAR FUNCTION 41 1791 2.587e-14 7.869e-13
154 REGULATION OF CELL MORPHOGENESIS 24 552 3.169e-14 9.574e-13
155 KIDNEY EPITHELIUM DEVELOPMENT 14 125 3.192e-14 9.582e-13
156 EPITHELIAL TO MESENCHYMAL TRANSITION 11 56 3.246e-14 9.681e-13
157 REGULATION OF CATENIN IMPORT INTO NUCLEUS 9 27 3.703e-14 1.097e-12
158 CELL CYCLE 35 1316 4.748e-14 1.398e-12
159 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 32 1087 4.835e-14 1.415e-12
160 PROTEIN PHOSPHORYLATION 30 944 4.919e-14 1.422e-12
161 REGIONALIZATION 19 311 4.908e-14 1.422e-12
162 TUBE FORMATION 14 129 4.981e-14 1.431e-12
163 POSITIVE REGULATION OF CELL PROLIFERATION 28 814 5.83e-14 1.654e-12
164 INTRACELLULAR SIGNAL TRANSDUCTION 38 1572 5.799e-14 1.654e-12
165 REPRODUCTIVE SYSTEM DEVELOPMENT 21 408 5.921e-14 1.67e-12
166 SINGLE ORGANISM CELL ADHESION 22 459 5.962e-14 1.671e-12
167 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 26 689 6.379e-14 1.777e-12
168 REGULATION OF CELL ADHESION 25 629 6.53e-14 1.809e-12
169 REGULATION OF ORGANELLE ORGANIZATION 33 1178 7.149e-14 1.968e-12
170 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 20 370 1.001e-13 2.74e-12
171 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY 13 110 1.357e-13 3.694e-12
172 PALATE DEVELOPMENT 12 85 1.381e-13 3.737e-12
173 REGULATION OF CYTOPLASMIC TRANSPORT 22 481 1.536e-13 4.131e-12
174 POSITIVE REGULATION OF KINASE ACTIVITY 22 482 1.602e-13 4.283e-12
175 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 23 541 1.86e-13 4.917e-12
176 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 23 541 1.86e-13 4.917e-12
177 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 19 337 2.073e-13 5.442e-12
178 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 24 602 2.082e-13 5.442e-12
179 RHYTHMIC PROCESS 18 298 2.916e-13 7.579e-12
180 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 24 616 3.414e-13 8.777e-12
181 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 24 616 3.414e-13 8.777e-12
182 REGULATION OF CELL CYCLE 29 949 3.781e-13 9.667e-12
183 NEURON DEVELOPMENT 25 687 4.672e-13 1.188e-11
184 NEURAL TUBE FORMATION 12 94 4.789e-13 1.211e-11
185 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 12 95 5.453e-13 1.372e-11
186 REGULATION OF GROWTH 24 633 6.119e-13 1.531e-11
187 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 36 7.104e-13 1.768e-11
188 OSTEOBLAST DIFFERENTIATION 13 126 8.058e-13 1.994e-11
189 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 19 365 8.556e-13 2.106e-11
190 POSITIVE REGULATION OF MAPK CASCADE 21 470 9.136e-13 2.226e-11
191 ANTERIOR POSTERIOR PATTERN SPECIFICATION 15 194 9.119e-13 2.226e-11
192 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 15 197 1.141e-12 2.764e-11
193 REGULATION OF BINDING 17 283 1.532e-12 3.675e-11
194 SKELETAL SYSTEM MORPHOGENESIS 15 201 1.528e-12 3.675e-11
195 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 9 39 1.575e-12 3.758e-11
196 ODONTOGENESIS 12 105 1.85e-12 4.393e-11
197 REGULATION OF HYDROLASE ACTIVITY 33 1327 1.936e-12 4.574e-11
198 MAMMARY GLAND MORPHOGENESIS 9 40 2.022e-12 4.751e-11
199 RESPONSE TO RETINOIC ACID 12 107 2.326e-12 5.439e-11
200 REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 7 16 2.886e-12 6.583e-11
201 STEM CELL PROLIFERATION 10 60 2.859e-12 6.583e-11
202 CHONDROCYTE DIFFERENTIATION 10 60 2.859e-12 6.583e-11
203 PARAXIAL MESODERM DEVELOPMENT 7 16 2.886e-12 6.583e-11
204 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 10 60 2.859e-12 6.583e-11
205 POSITIVE REGULATION OF CATALYTIC ACTIVITY 35 1518 2.997e-12 6.802e-11
206 DEVELOPMENTAL INDUCTION 8 27 3.061e-12 6.915e-11
207 RESPONSE TO LIPID 27 888 3.209e-12 7.214e-11
208 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 40 1977 3.241e-12 7.251e-11
209 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 43 4.106e-12 9.141e-11
210 PROTEIN LOCALIZATION 38 1805 4.172e-12 9.244e-11
211 CELL DIVISION 20 460 5.539e-12 1.222e-10
212 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 8 29 5.859e-12 1.274e-10
213 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 8 29 5.859e-12 1.274e-10
214 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 8 29 5.859e-12 1.274e-10
215 FOREBRAIN DEVELOPMENT 18 357 6.126e-12 1.326e-10
216 DIGESTIVE SYSTEM DEVELOPMENT 13 148 6.438e-12 1.387e-10
217 CELLULAR RESPONSE TO RETINOIC ACID 10 65 6.617e-12 1.419e-10
218 SEGMENTATION 11 89 6.726e-12 1.436e-10
219 IN UTERO EMBRYONIC DEVELOPMENT 17 311 6.924e-12 1.471e-10
220 PHOSPHORYLATION 31 1228 7.309e-12 1.546e-10
221 REGULATION OF CHONDROCYTE DIFFERENTIATION 9 46 7.9e-12 1.663e-10
222 POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 12 119 8.376e-12 1.756e-10
223 DORSAL VENTRAL PATTERN FORMATION 11 91 8.627e-12 1.8e-10
224 CELL CYCLE PROCESS 29 1081 9.355e-12 1.943e-10
225 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 15 229 1.003e-11 2.074e-10
226 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 18 368 1.015e-11 2.089e-10
227 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 13 154 1.07e-11 2.193e-10
228 REGULATION OF ORGAN FORMATION 8 32 1.414e-11 2.886e-10
229 REGULATION OF DEPHOSPHORYLATION 13 158 1.483e-11 3.013e-10
230 EAR DEVELOPMENT 14 195 1.494e-11 3.022e-10
231 NEURON PROJECTION DEVELOPMENT 21 545 1.507e-11 3.035e-10
232 NEGATIVE REGULATION OF CELL CYCLE 19 433 1.691e-11 3.391e-10
233 DORSAL VENTRAL AXIS SPECIFICATION 7 20 1.917e-11 3.828e-10
234 LOCOMOTION 29 1114 1.936e-11 3.85e-10
235 CELL JUNCTION ASSEMBLY 12 129 2.194e-11 4.345e-10
236 REGULATION OF DEVELOPMENTAL GROWTH 16 289 2.487e-11 4.884e-10
237 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 16 289 2.487e-11 4.884e-10
238 PROTEIN COMPLEX BIOGENESIS 29 1132 2.847e-11 5.543e-10
239 PROTEIN COMPLEX ASSEMBLY 29 1132 2.847e-11 5.543e-10
240 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 10 75 2.911e-11 5.645e-10
241 REPRODUCTION 31 1297 2.943e-11 5.681e-10
242 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 12 135 3.762e-11 7.234e-10
243 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 11 104 3.805e-11 7.286e-10
244 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 21 573 3.831e-11 7.307e-10
245 REGULATION OF CELLULAR COMPONENT MOVEMENT 24 771 3.858e-11 7.327e-10
246 POSITIVE REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 6 12 4.081e-11 7.719e-10
247 REGULATION OF KIDNEY DEVELOPMENT 9 55 4.355e-11 8.204e-10
248 REGULATION OF FAT CELL DIFFERENTIATION 11 106 4.694e-11 8.807e-10
249 NEGATIVE REGULATION OF MOLECULAR FUNCTION 28 1079 4.99e-11 9.325e-10
250 NEGATIVE REGULATION OF CELL DEVELOPMENT 16 303 5.04e-11 9.381e-10
251 POSITIVE REGULATION OF TRANSPORT 26 936 6.388e-11 1.184e-09
252 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 6 13 7.541e-11 1.392e-09
253 NEGATIVE REGULATION OF CELL DEATH 25 872 8.164e-11 1.501e-09
254 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 10 84 9.262e-11 1.697e-09
255 NEGATIVE REGULATION OF PHOSPHORYLATION 18 422 9.618e-11 1.755e-09
256 REGULATION OF MAP KINASE ACTIVITY 16 319 1.081e-10 1.957e-09
257 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 23 740 1.078e-10 1.957e-09
258 CELL CELL ADHESION 21 608 1.144e-10 2.063e-09
259 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY INVOLVED IN NEURAL TUBE CLOSURE 6 14 1.313e-10 2.359e-09
260 RESPONSE TO OXYGEN CONTAINING COMPOUND 31 1381 1.42e-10 2.541e-09
261 ESTABLISHMENT OF CELL POLARITY 10 88 1.484e-10 2.645e-09
262 REGULATION OF CELL CELL ADHESION 17 380 1.603e-10 2.846e-09
263 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 18 437 1.695e-10 2.998e-09
264 REGULATION OF CELLULAR RESPONSE TO STRESS 22 691 1.843e-10 3.249e-09
265 AXIS SPECIFICATION 10 90 1.861e-10 3.268e-09
266 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 11 121 1.997e-10 3.493e-09
267 AXIS ELONGATION 7 27 2.12e-10 3.694e-09
268 INNER EAR MORPHOGENESIS 10 92 2.322e-10 4.031e-09
269 RESPONSE TO ORGANIC CYCLIC COMPOUND 25 917 2.349e-10 4.064e-09
270 CELL ACTIVATION 20 568 2.386e-10 4.111e-09
271 CELL DEATH 26 1001 2.737e-10 4.7e-09
272 MAMMARY GLAND DUCT MORPHOGENESIS 7 28 2.812e-10 4.81e-09
273 CELLULAR RESPONSE TO LIPID 18 457 3.485e-10 5.94e-09
274 REGULATION OF HEART MORPHOGENESIS 7 29 3.688e-10 6.263e-09
275 NEURON PROJECTION MORPHOGENESIS 17 402 3.811e-10 6.448e-09
276 REGULATION OF MEMBRANE PERMEABILITY 9 70 4.126e-10 6.956e-09
277 RESPONSE TO ABIOTIC STIMULUS 26 1024 4.454e-10 7.482e-09
278 RESPONSE TO EXTERNAL STIMULUS 35 1821 4.67e-10 7.8e-09
279 DIGESTIVE TRACT MORPHOGENESIS 8 48 4.677e-10 7.8e-09
280 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 29 1275 4.739e-10 7.875e-09
281 APPENDAGE DEVELOPMENT 12 169 5.197e-10 8.575e-09
282 LIMB DEVELOPMENT 12 169 5.197e-10 8.575e-09
283 CELL CYCLE PHASE TRANSITION 14 255 5.28e-10 8.682e-09
284 BRANCH ELONGATION OF AN EPITHELIUM 6 17 5.332e-10 8.735e-09
285 REGULATION OF ORGAN GROWTH 9 73 6.066e-10 9.869e-09
286 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 9 73 6.066e-10 9.869e-09
287 REGULATION OF MUSCLE TISSUE DEVELOPMENT 10 103 7.182e-10 1.16e-08
288 REGULATION OF MUSCLE ORGAN DEVELOPMENT 10 103 7.182e-10 1.16e-08
289 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 14 262 7.519e-10 1.211e-08
290 MACROMOLECULAR COMPLEX ASSEMBLY 30 1398 8.87e-10 1.423e-08
291 CELL PROJECTION ORGANIZATION 24 902 9.282e-10 1.484e-08
292 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 8 53 1.071e-09 1.707e-08
293 MACROMOLECULAR COMPLEX DISASSEMBLY 12 182 1.218e-09 1.935e-08
294 REGULATION OF MESENCHYMAL CELL PROLIFERATION 7 34 1.24e-09 1.962e-08
295 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 13 228 1.432e-09 2.258e-08
296 REGULATION OF JUN KINASE ACTIVITY 9 81 1.565e-09 2.46e-08
297 EAR MORPHOGENESIS 10 112 1.646e-09 2.578e-08
298 KIDNEY MORPHOGENESIS 9 82 1.749e-09 2.731e-08
299 NEPHRON DEVELOPMENT 10 115 2.134e-09 3.321e-08
300 EMBRYONIC PATTERN SPECIFICATION 8 58 2.258e-09 3.502e-08
301 COCHLEA MORPHOGENESIS 6 21 2.292e-09 3.542e-08
302 ESTABLISHMENT OR MAINTENANCE OF APICAL BASAL CELL POLARITY 7 37 2.337e-09 3.588e-08
303 ESTABLISHMENT OR MAINTENANCE OF BIPOLAR CELL POLARITY 7 37 2.337e-09 3.588e-08
304 CARDIAC SEPTUM DEVELOPMENT 9 85 2.42e-09 3.704e-08
305 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 11 153 2.477e-09 3.778e-08
306 REGULATION OF RESPONSE TO STRESS 30 1468 2.796e-09 4.252e-08
307 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 23 876 2.83e-09 4.289e-08
308 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 16 404 3.343e-09 5.051e-08
309 POSITIVE REGULATION OF STEM CELL PROLIFERATION 8 61 3.417e-09 5.145e-08
310 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 17 465 3.455e-09 5.186e-08
311 REGULATION OF JNK CASCADE 11 159 3.72e-09 5.565e-08
312 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 10 122 3.808e-09 5.679e-08
313 SOMITOGENESIS 8 62 3.903e-09 5.802e-08
314 VASCULATURE DEVELOPMENT 17 469 3.927e-09 5.819e-08
315 APICAL JUNCTION ASSEMBLY 7 40 4.168e-09 6.156e-08
316 POSITIVE REGULATION OF JUN KINASE ACTIVITY 8 63 4.448e-09 6.55e-08
317 MEMBRANE ORGANIZATION 23 899 4.621e-09 6.782e-08
318 MITOCHONDRIAL MEMBRANE ORGANIZATION 9 92 4.927e-09 7.21e-08
319 POSITIVE REGULATION OF MAP KINASE ACTIVITY 12 207 5.26e-09 7.672e-08
320 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 9 93 5.428e-09 7.868e-08
321 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 22 829 5.422e-09 7.868e-08
322 REGULATION OF PROTEIN PHOSPHATASE TYPE 2A ACTIVITY 6 24 5.6e-09 8.092e-08
323 PITUITARY GLAND DEVELOPMENT 7 42 5.971e-09 8.574e-08
324 MAMMARY GLAND EPITHELIAL CELL PROLIFERATION 5 12 5.952e-09 8.574e-08
325 REGULATION OF PHOSPHATASE ACTIVITY 10 128 6.078e-09 8.702e-08
326 SKIN DEVELOPMENT 12 211 6.525e-09 9.313e-08
327 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 10 129 6.555e-09 9.328e-08
328 BETA CATENIN TCF COMPLEX ASSEMBLY 7 43 7.096e-09 1.007e-07
329 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 7 44 8.396e-09 1.187e-07
330 MUSCLE STRUCTURE DEVELOPMENT 16 432 8.647e-09 1.219e-07
331 SEX DIFFERENTIATION 13 266 9.203e-09 1.294e-07
332 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 6 26 9.484e-09 1.329e-07
333 CELL PART MORPHOGENESIS 19 633 9.62e-09 1.344e-07
334 EYE MORPHOGENESIS 10 136 1.093e-08 1.523e-07
335 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 8 71 1.173e-08 1.63e-07
336 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 6 27 1.213e-08 1.68e-07
337 CELL CYCLE G2 M PHASE TRANSITION 10 138 1.259e-08 1.738e-07
338 POSITIVE REGULATION OF PROTEIN IMPORT 9 104 1.466e-08 2.018e-07
339 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 5 14 1.49e-08 2.045e-07
340 VENTRICULAR SEPTUM MORPHOGENESIS 6 28 1.536e-08 2.097e-07
341 DOPAMINERGIC NEURON DIFFERENTIATION 6 28 1.536e-08 2.097e-07
342 IMMUNE SYSTEM DEVELOPMENT 18 582 1.555e-08 2.115e-07
343 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 7 48 1.581e-08 2.145e-07
344 CELL CELL JUNCTION ASSEMBLY 8 74 1.637e-08 2.214e-07
345 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 8 75 1.823e-08 2.459e-07
346 CARDIAC SEPTUM MORPHOGENESIS 7 49 1.835e-08 2.468e-07
347 CARDIAC CHAMBER DEVELOPMENT 10 144 1.895e-08 2.541e-07
348 STEM CELL DIVISION 6 29 1.928e-08 2.577e-07
349 DIENCEPHALON DEVELOPMENT 8 77 2.251e-08 3.001e-07
350 TAXIS 16 464 2.353e-08 3.128e-07
351 ESTABLISHMENT OR MAINTENANCE OF EPITHELIAL CELL APICAL BASAL POLARITY 6 30 2.398e-08 3.178e-07
352 RENAL TUBULE DEVELOPMENT 8 78 2.496e-08 3.29e-07
353 SOMITE DEVELOPMENT 8 78 2.496e-08 3.29e-07
354 BONE MORPHOGENESIS 8 79 2.763e-08 3.631e-07
355 WOUND HEALING 16 470 2.812e-08 3.686e-07
356 MESONEPHRIC TUBULE MORPHOGENESIS 7 53 3.227e-08 4.195e-07
357 ORGAN INDUCTION 5 16 3.219e-08 4.195e-07
358 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 7 53 3.227e-08 4.195e-07
359 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 19 684 3.314e-08 4.296e-07
360 BICELLULAR TIGHT JUNCTION ASSEMBLY 6 32 3.623e-08 4.683e-07
361 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 11 199 3.848e-08 4.959e-07
362 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 9 117 4.124e-08 5.301e-07
363 CRANIAL SKELETAL SYSTEM DEVELOPMENT 7 55 4.206e-08 5.392e-07
364 POSITIVE REGULATION OF EMBRYONIC DEVELOPMENT 6 33 4.406e-08 5.632e-07
365 NEGATIVE REGULATION OF STEM CELL PROLIFERATION 5 17 4.538e-08 5.773e-07
366 REGULATION OF NEURON DIFFERENTIATION 17 554 4.541e-08 5.773e-07
367 RESPONSE TO ALCOHOL 14 362 4.611e-08 5.846e-07
368 POSITIVE REGULATION OF NEURON DIFFERENTIATION 13 306 4.824e-08 6.099e-07
369 EPIDERMIS DEVELOPMENT 12 253 4.907e-08 6.187e-07
370 BLOOD VESSEL MORPHOGENESIS 14 364 4.937e-08 6.209e-07
371 NEURON PROJECTION GUIDANCE 11 205 5.217e-08 6.543e-07
372 ORGAN FORMATION 6 34 5.324e-08 6.659e-07
373 LEUKOCYTE CELL CELL ADHESION 12 255 5.349e-08 6.673e-07
374 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 9 121 5.527e-08 6.876e-07
375 RESPONSE TO WOUNDING 17 563 5.73e-08 7.109e-07
376 BIOLOGICAL ADHESION 23 1032 5.94e-08 7.351e-07
377 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 12 258 6.081e-08 7.505e-07
378 ENDOCRINE SYSTEM DEVELOPMENT 9 123 6.373e-08 7.845e-07
379 REGULATION OF CYTOSKELETON ORGANIZATION 16 502 6.975e-08 8.563e-07
380 EPITHELIAL CELL PROLIFERATION 8 89 7.109e-08 8.705e-07
381 POSITIVE REGULATION OF CELL ADHESION 14 376 7.374e-08 9.005e-07
382 NEGATIVE REGULATION OF MUSCLE ORGAN DEVELOPMENT 6 36 7.634e-08 9.274e-07
383 NEGATIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 6 36 7.634e-08 9.274e-07
384 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 10 167 7.756e-08 9.398e-07
385 RESPONSE TO ACID CHEMICAL 13 319 7.836e-08 9.471e-07
386 REGULATION OF PROTEIN BINDING 10 168 8.205e-08 9.89e-07
387 EMBRYONIC DIGIT MORPHOGENESIS 7 61 8.774e-08 1.055e-06
388 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 9 128 9e-08 1.079e-06
389 REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 6 37 9.066e-08 1.084e-06
390 NEGATIVE REGULATION OF CELL GROWTH 10 170 9.172e-08 1.094e-06
391 RESPONSE TO ESTROGEN 11 218 9.761e-08 1.162e-06
392 NEPHRON EPITHELIUM DEVELOPMENT 8 93 1.005e-07 1.192e-06
393 SINGLE ORGANISM CELLULAR LOCALIZATION 21 898 1.094e-07 1.295e-06
394 TRACHEA DEVELOPMENT 5 20 1.121e-07 1.32e-06
395 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 5 20 1.121e-07 1.32e-06
396 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 8 95 1.187e-07 1.395e-06
397 CELLULAR RESPONSE TO ACID CHEMICAL 10 175 1.204e-07 1.408e-06
398 GLIOGENESIS 10 175 1.204e-07 1.408e-06
399 COCHLEA DEVELOPMENT 6 39 1.26e-07 1.469e-06
400 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 9 135 1.424e-07 1.656e-06
401 NEGATIVE REGULATION OF ORGAN GROWTH 5 21 1.464e-07 1.698e-06
402 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 12 282 1.599e-07 1.851e-06
403 REGULATION OF DNA METABOLIC PROCESS 13 340 1.638e-07 1.891e-06
404 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 6 41 1.719e-07 1.98e-06
405 LYMPHOCYTE ACTIVATION 13 342 1.752e-07 2.013e-06
406 ACTIVIN RECEPTOR SIGNALING PATHWAY 5 22 1.885e-07 2.155e-06
407 SOMATIC STEM CELL DIVISION 5 22 1.885e-07 2.155e-06
408 CELL CELL SIGNALING 19 767 1.978e-07 2.256e-06
409 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 8 102 2.067e-07 2.351e-06
410 EPITHELIAL CELL DEVELOPMENT 10 186 2.127e-07 2.414e-06
411 REGULATION OF CIRCADIAN RHYTHM 8 103 2.229e-07 2.524e-06
412 NEURAL PRECURSOR CELL PROLIFERATION 7 70 2.304e-07 2.602e-06
413 LEUKOCYTE DIFFERENTIATION 12 292 2.328e-07 2.62e-06
414 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 9 143 2.331e-07 2.62e-06
415 LEUKOCYTE ACTIVATION 14 414 2.392e-07 2.681e-06
416 REGULATION OF METANEPHROS DEVELOPMENT 5 23 2.397e-07 2.681e-06
417 CARDIAC CHAMBER MORPHOGENESIS 8 104 2.403e-07 2.681e-06
418 ENDODERM DEVELOPMENT 7 71 2.543e-07 2.831e-06
419 SYNAPSE ORGANIZATION 9 145 2.624e-07 2.914e-06
420 POSITIVE REGULATION OF LOCOMOTION 14 420 2.847e-07 3.154e-06
421 REGULATION OF CELL CYCLE PROCESS 16 558 2.922e-07 3.229e-06
422 ENDOCHONDRAL BONE MORPHOGENESIS 6 45 3.052e-07 3.366e-06
423 PANCREAS DEVELOPMENT 7 73 3.085e-07 3.393e-06
424 REGULATION OF PROTEOLYSIS 18 711 3.128e-07 3.425e-06
425 MALE SEX DIFFERENTIATION 9 148 3.124e-07 3.425e-06
426 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 6 46 3.493e-07 3.806e-06
427 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 6 46 3.493e-07 3.806e-06
428 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 19 799 3.694e-07 4.016e-06
429 RESPONSE TO STEROID HORMONE 15 497 3.708e-07 4.022e-06
430 LENS FIBER CELL DIFFERENTIATION 5 25 3.748e-07 4.046e-06
431 POSITIVE REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 5 25 3.748e-07 4.046e-06
432 NEGATIVE REGULATION OF KINASE ACTIVITY 11 250 3.866e-07 4.164e-06
433 POSITIVE REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 4 11 4.207e-07 4.521e-06
434 CELL CYCLE ARREST 9 154 4.375e-07 4.691e-06
435 REGULATION OF BMP SIGNALING PATHWAY 7 77 4.462e-07 4.773e-06
436 RESPONSE TO HORMONE 20 893 4.534e-07 4.828e-06
437 ANTERIOR POSTERIOR AXIS SPECIFICATION 6 48 4.531e-07 4.828e-06
438 OVULATION CYCLE 8 113 4.561e-07 4.845e-06
439 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 14 437 4.589e-07 4.864e-06
440 NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT 5 26 4.617e-07 4.883e-06
441 BONE DEVELOPMENT 9 156 4.88e-07 5.148e-06
442 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 8 115 5.218e-07 5.493e-06
443 RESPONSE TO LITHIUM ION 5 27 5.639e-07 5.923e-06
444 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 8 117 5.956e-07 6.241e-06
445 ANATOMICAL STRUCTURE REGRESSION 4 12 6.281e-07 6.524e-06
446 REGULATION OF MACROPHAGE CYTOKINE PRODUCTION 4 12 6.281e-07 6.524e-06
447 TRACHEA MORPHOGENESIS 4 12 6.281e-07 6.524e-06
448 LYMPHOCYTE DIFFERENTIATION 10 209 6.239e-07 6.524e-06
449 METANEPHROS DEVELOPMENT 7 81 6.323e-07 6.553e-06
450 REGULATION OF DNA REPLICATION 9 161 6.366e-07 6.582e-06
451 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 11 263 6.389e-07 6.591e-06
452 CELL FATE COMMITMENT INVOLVED IN FORMATION OF PRIMARY GERM LAYER 5 28 6.831e-07 7.032e-06
453 REGULATION OF PROTEIN CATABOLIC PROCESS 13 393 8.478e-07 8.708e-06
454 T CELL DIFFERENTIATION 8 123 8.725e-07 8.942e-06
455 REGULATION OF CELL DIVISION 11 272 8.897e-07 9.099e-06
456 GDP METABOLIC PROCESS 4 13 9.03e-07 9.215e-06
457 POSITIVE REGULATION OF CELL CYCLE 12 332 9.107e-07 9.272e-06
458 REGULATION OF MITOCHONDRION ORGANIZATION 10 218 9.168e-07 9.314e-06
459 MITOTIC CELL CYCLE 18 766 9.202e-07 9.329e-06
460 VENTRICULAR SEPTUM DEVELOPMENT 6 54 9.255e-07 9.362e-06
461 REGULATION OF PROTEIN STABILITY 10 221 1.038e-06 1.045e-05
462 REGULATION OF MITOTIC CELL CYCLE 14 468 1.037e-06 1.045e-05
463 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 8 126 1.048e-06 1.053e-05
464 POSITIVE REGULATION OF BINDING 8 127 1.113e-06 1.115e-05
465 OVULATION CYCLE PROCESS 7 88 1.114e-06 1.115e-05
466 NEGATIVE REGULATION OF CELL ADHESION 10 223 1.127e-06 1.125e-05
467 EMBRYONIC SKELETAL JOINT DEVELOPMENT 4 14 1.258e-06 1.254e-05
468 CIRCADIAN REGULATION OF GENE EXPRESSION 6 57 1.281e-06 1.271e-05
469 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 6 57 1.281e-06 1.271e-05
470 ENDOCARDIAL CUSHION DEVELOPMENT 5 32 1.373e-06 1.359e-05
471 MITOCHONDRIAL TRANSPORT 9 177 1.406e-06 1.389e-05
472 VASCULOGENESIS 6 59 1.575e-06 1.553e-05
473 EMBRYONIC AXIS SPECIFICATION 5 33 1.61e-06 1.584e-05
474 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 12 351 1.629e-06 1.599e-05
475 REGULATION OF PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 6 60 1.741e-06 1.706e-05
476 BRAIN MORPHOGENESIS 5 34 1.878e-06 1.836e-05
477 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 17 724 1.926e-06 1.878e-05
478 CIRCADIAN RHYTHM 8 137 1.972e-06 1.92e-05
479 POSITIVE REGULATION OF DNA METABOLIC PROCESS 9 185 2.027e-06 1.969e-05
480 PROTEIN LOCALIZATION TO SYNAPSE 4 16 2.266e-06 2.192e-05
481 APOPTOTIC PROCESS INVOLVED IN MORPHOGENESIS 4 16 2.266e-06 2.192e-05
482 POSITIVE REGULATION OF PROTEOLYSIS 12 363 2.308e-06 2.228e-05
483 POSITIVE REGULATION OF CELL CELL ADHESION 10 243 2.442e-06 2.353e-05
484 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 7 99 2.473e-06 2.372e-05
485 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 7 99 2.473e-06 2.372e-05
486 HEAD MORPHOGENESIS 5 36 2.52e-06 2.413e-05
487 PROTEIN DEPHOSPHORYLATION 9 190 2.526e-06 2.413e-05
488 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 11 303 2.542e-06 2.424e-05
489 EPIDERMAL CELL DIFFERENTIATION 8 142 2.581e-06 2.456e-05
490 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 9 191 2.637e-06 2.504e-05
491 CAMERA TYPE EYE MORPHOGENESIS 7 101 2.828e-06 2.68e-05
492 CELLULAR RESPONSE TO LITHIUM ION 4 17 2.95e-06 2.784e-05
493 ESTABLISHMENT OF TISSUE POLARITY 4 17 2.95e-06 2.784e-05
494 NEGATIVE REGULATION OF MAPK CASCADE 8 145 3.017e-06 2.842e-05
495 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 6 66 3.068e-06 2.878e-05
496 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 6 66 3.068e-06 2.878e-05
497 CELL MOTILITY 18 835 3.117e-06 2.912e-05
498 LOCALIZATION OF CELL 18 835 3.117e-06 2.912e-05
499 RESPONSE TO ESTRADIOL 8 146 3.176e-06 2.956e-05
500 CELLULAR COMPONENT DISASSEMBLY 14 515 3.172e-06 2.956e-05
501 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 7 103 3.226e-06 2.996e-05
502 NEURON FATE COMMITMENT 6 67 3.353e-06 3.107e-05
503 REGULATION OF ACTIN FILAMENT BASED PROCESS 11 312 3.368e-06 3.116e-05
504 KIDNEY MESENCHYME DEVELOPMENT 4 18 3.775e-06 3.485e-05
505 NEGATIVE REGULATION OF OSSIFICATION 6 69 3.987e-06 3.667e-05
506 SYNAPSE ASSEMBLY 6 69 3.987e-06 3.667e-05
507 REGULATION OF CELLULAR COMPONENT BIOGENESIS 17 767 4.172e-06 3.829e-05
508 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 5 40 4.314e-06 3.951e-05
509 SKIN EPIDERMIS DEVELOPMENT 6 71 4.717e-06 4.312e-05
510 REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 4 19 4.759e-06 4.325e-05
511 ENTRAINMENT OF CIRCADIAN CLOCK BY PHOTOPERIOD 4 19 4.759e-06 4.325e-05
512 POSITIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 4 19 4.759e-06 4.325e-05
513 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 5 41 4.889e-06 4.417e-05
514 LUNG ALVEOLUS DEVELOPMENT 5 41 4.889e-06 4.417e-05
515 RECEPTOR CLUSTERING 5 41 4.889e-06 4.417e-05
516 NEGATIVE REGULATION OF LOCOMOTION 10 263 4.935e-06 4.45e-05
517 REGULATION OF CELL GROWTH 12 391 4.944e-06 4.45e-05
518 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 7 111 5.312e-06 4.771e-05
519 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 9 209 5.504e-06 4.934e-05
520 POSTTRANSCRIPTIONAL GENE SILENCING 5 42 5.523e-06 4.942e-05
521 POSITIVE REGULATION OF PROTEIN BINDING 6 73 5.551e-06 4.957e-05
522 TONGUE DEVELOPMENT 4 20 5.92e-06 5.257e-05
523 GMP METABOLIC PROCESS 4 20 5.92e-06 5.257e-05
524 NEGATIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 4 20 5.92e-06 5.257e-05
525 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 5 43 6.219e-06 5.512e-05
526 BODY MORPHOGENESIS 5 44 6.983e-06 6.177e-05
527 FEMALE SEX DIFFERENTIATION 7 116 7.111e-06 6.279e-05
528 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 9 216 7.185e-06 6.332e-05
529 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 12 406 7.24e-06 6.368e-05
530 APOPTOTIC PROCESS INVOLVED IN DEVELOPMENT 4 21 7.279e-06 6.378e-05
531 NEGATIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 4 21 7.279e-06 6.378e-05
532 LUNG MORPHOGENESIS 5 45 7.817e-06 6.812e-05
533 THYMOCYTE AGGREGATION 5 45 7.817e-06 6.812e-05
534 T CELL DIFFERENTIATION IN THYMUS 5 45 7.817e-06 6.812e-05
535 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 7 118 7.96e-06 6.923e-05
536 REGULATION OF EPITHELIAL CELL MIGRATION 8 166 8.21e-06 7.114e-05
537 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 8 166 8.21e-06 7.114e-05
538 ENDOCARDIAL CUSHION MORPHOGENESIS 4 22 8.854e-06 7.658e-05
539 POSITIVE REGULATION OF HYDROLASE ACTIVITY 18 905 9.443e-06 8.152e-05
540 REGULATION OF CATABOLIC PROCESS 16 731 9.603e-06 8.275e-05
541 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 7 122 9.912e-06 8.51e-05
542 LOCALIZATION WITHIN MEMBRANE 7 122 9.912e-06 8.51e-05
543 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 4 23 1.067e-05 9.125e-05
544 POSITIVE REGULATION OF COLLAGEN METABOLIC PROCESS 4 23 1.067e-05 9.125e-05
545 REGULATION OF CELL SUBSTRATE ADHESION 8 173 1.11e-05 9.464e-05
546 TELENCEPHALON DEVELOPMENT 9 228 1.11e-05 9.464e-05
547 HAIR CYCLE 6 83 1.171e-05 9.945e-05
548 MOLTING CYCLE 6 83 1.171e-05 9.945e-05
549 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 6 84 1.255e-05 0.0001064
550 PHOTOPERIODISM 4 24 1.274e-05 0.0001073
551 REGULATION OF LEUKOCYTE DIFFERENTIATION 9 232 1.275e-05 0.0001073
552 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 4 24 1.274e-05 0.0001073
553 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 9 232 1.275e-05 0.0001073
554 RESPONSE TO DRUG 12 431 1.318e-05 0.0001106
555 REGULATION OF VASCULATURE DEVELOPMENT 9 233 1.32e-05 0.0001106
556 FACE DEVELOPMENT 5 50 1.323e-05 0.0001107
557 CYTOSKELETON ORGANIZATION 17 838 1.33e-05 0.0001111
558 REGULATION OF REPRODUCTIVE PROCESS 7 129 1.428e-05 0.0001191
559 POSITIVE REGULATION OF DNA REPLICATION 6 86 1.437e-05 0.0001196
560 POSITIVE REGULATION OF FAT CELL DIFFERENTIATION 5 51 1.46e-05 0.0001213
561 REGULATION OF CHEMOTAXIS 8 180 1.482e-05 0.0001229
562 FOREBRAIN REGIONALIZATION 4 25 1.51e-05 0.0001249
563 MUSCLE CELL DIFFERENTIATION 9 237 1.511e-05 0.0001249
564 POSITIVE REGULATION OF GROWTH 9 238 1.562e-05 0.0001289
565 PROTEIN STABILIZATION 7 131 1.579e-05 0.00013
566 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 6 88 1.64e-05 0.0001349
567 POSITIVE REGULATION OF CELL DIVISION 7 132 1.659e-05 0.0001359
568 MAINTENANCE OF CELL NUMBER 7 132 1.659e-05 0.0001359
569 DEVELOPMENTAL PROGRAMMED CELL DEATH 4 26 1.776e-05 0.0001447
570 ENTRAINMENT OF CIRCADIAN CLOCK 4 26 1.776e-05 0.0001447
571 REGULATION OF CELL FATE COMMITMENT 4 26 1.776e-05 0.0001447
572 REGULATION OF MICROTUBULE BASED PROCESS 9 243 1.842e-05 0.0001499
573 ENDOTHELIUM DEVELOPMENT 6 90 1.866e-05 0.000151
574 REGULATION OF CELL MATRIX ADHESION 6 90 1.866e-05 0.000151
575 REGULATION OF GLIOGENESIS 6 90 1.866e-05 0.000151
576 PROTEIN LOCALIZATION TO MEMBRANE 11 376 1.95e-05 0.0001575
577 HINDBRAIN DEVELOPMENT 7 137 2.111e-05 0.0001702
578 RESPONSE TO OXYGEN LEVELS 10 311 2.122e-05 0.0001708
579 CELLULAR RESPONSE TO STRESS 24 1565 2.206e-05 0.0001772
580 NEGATIVE REGULATION OF CELL CELL ADHESION 7 138 2.213e-05 0.0001775
581 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 5 56 2.317e-05 0.0001852
582 OUTFLOW TRACT MORPHOGENESIS 5 56 2.317e-05 0.0001852
583 GASTRULATION WITH MOUTH FORMING SECOND 4 28 2.409e-05 0.000191
584 NEGATIVE REGULATION OF TRANSPORT 12 458 2.401e-05 0.000191
585 REGULATION OF NEUROBLAST PROLIFERATION 4 28 2.409e-05 0.000191
586 MORPHOGENESIS OF A POLARIZED EPITHELIUM 4 28 2.409e-05 0.000191
587 METANEPHROS MORPHOGENESIS 4 28 2.409e-05 0.000191
588 CARDIAC MUSCLE TISSUE DEVELOPMENT 7 140 2.428e-05 0.0001921
589 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 4 29 2.782e-05 0.0002186
590 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 4 29 2.782e-05 0.0002186
591 REGULATION OF OLIGODENDROCYTE DIFFERENTIATION 4 29 2.782e-05 0.0002186
592 NEUROBLAST PROLIFERATION 4 29 2.782e-05 0.0002186
593 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 6 97 2.861e-05 0.0002245
594 POSITIVE REGULATION OF CATABOLIC PROCESS 11 395 3.065e-05 0.0002401
595 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 6 100 3.4e-05 0.0002659
596 PEPTIDYL SERINE MODIFICATION 7 148 3.47e-05 0.0002709
597 REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 6 101 3.597e-05 0.0002803
598 REGULATION OF IMMUNE SYSTEM PROCESS 22 1403 3.684e-05 0.0002867
599 REGULATION OF CYTOKINE PRODUCTION 13 563 4.044e-05 0.0003141
600 SALIVARY GLAND DEVELOPMENT 4 32 4.152e-05 0.0003215
601 POSITIVE REGULATION OF BMP SIGNALING PATHWAY 4 32 4.152e-05 0.0003215
602 NEGATIVE REGULATION OF CARDIAC MUSCLE TISSUE GROWTH 3 12 4.68e-05 0.0003597
603 REGULATION OF T CELL APOPTOTIC PROCESS 4 33 4.703e-05 0.0003597
604 REGULATION OF THYMOCYTE APOPTOTIC PROCESS 3 12 4.68e-05 0.0003597
605 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 4 33 4.703e-05 0.0003597
606 HEART FORMATION 3 12 4.68e-05 0.0003597
607 CARDIAC VENTRICLE DEVELOPMENT 6 106 4.723e-05 0.0003597
608 FAT CELL DIFFERENTIATION 6 106 4.723e-05 0.0003597
609 EMBRYONIC EYE MORPHOGENESIS 4 33 4.703e-05 0.0003597
610 NEGATIVE REGULATION OF HEART GROWTH 3 12 4.68e-05 0.0003597
611 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 9 274 4.717e-05 0.0003597
612 ORGANELLE LOCALIZATION 11 415 4.797e-05 0.0003647
613 MUSCLE TISSUE DEVELOPMENT 9 275 4.852e-05 0.0003674
614 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 7 156 4.856e-05 0.0003674
615 PROTEIN LOCALIZATION TO NUCLEUS 7 156 4.856e-05 0.0003674
616 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 8 213 4.942e-05 0.0003733
617 NEURAL NUCLEUS DEVELOPMENT 5 66 5.163e-05 0.0003894
618 HORMONE MEDIATED SIGNALING PATHWAY 7 158 5.265e-05 0.0003964
619 LUNG EPITHELIUM DEVELOPMENT 4 34 5.305e-05 0.0003988
620 ACTIVATION OF PROTEIN KINASE ACTIVITY 9 279 5.425e-05 0.0004071
621 MICROTUBULE CYTOSKELETON ORGANIZATION 10 348 5.492e-05 0.0004115
622 POSITIVE REGULATION OF NEURON DEATH 5 67 5.552e-05 0.0004147
623 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 5 67 5.552e-05 0.0004147
624 REGENERATION 7 161 5.931e-05 0.0004423
625 NEURONAL STEM CELL DIVISION 3 13 6.057e-05 0.0004438
626 NEGATIVE REGULATION OF OLIGODENDROCYTE DIFFERENTIATION 3 13 6.057e-05 0.0004438
627 TYPE B PANCREATIC CELL DEVELOPMENT 3 13 6.057e-05 0.0004438
628 POSITIVE REGULATION OF STEROID BIOSYNTHETIC PROCESS 3 13 6.057e-05 0.0004438
629 REGULATION OF CELL PROLIFERATION INVOLVED IN KIDNEY DEVELOPMENT 3 13 6.057e-05 0.0004438
630 NEUROBLAST DIVISION 3 13 6.057e-05 0.0004438
631 MESENCHYMAL CELL PROLIFERATION 3 13 6.057e-05 0.0004438
632 REGULATION OF CELL FATE SPECIFICATION 3 13 6.057e-05 0.0004438
633 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 5 68 5.964e-05 0.0004438
634 MESODERMAL CELL FATE COMMITMENT 3 13 6.057e-05 0.0004438
635 POSITIVE REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 3 13 6.057e-05 0.0004438
636 REGULATION OF GTPASE ACTIVITY 14 673 6.249e-05 0.0004572
637 REGULATION OF NUCLEAR DIVISION 7 163 6.413e-05 0.0004684
638 DEPHOSPHORYLATION 9 286 6.564e-05 0.0004788
639 ESTABLISHMENT OF LOCALIZATION IN CELL 24 1676 6.624e-05 0.0004824
640 RESPONSE TO NITROGEN COMPOUND 16 859 6.773e-05 0.0004924
641 MUSCLE ORGAN MORPHOGENESIS 5 70 6.858e-05 0.0004978
642 REGULATION OF ENDOTHELIAL CELL MIGRATION 6 114 7.097e-05 0.0005144
643 CELL FATE SPECIFICATION 5 71 7.341e-05 0.0005313
644 HINDLIMB MORPHOGENESIS 4 37 7.449e-05 0.0005373
645 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 4 37 7.449e-05 0.0005373
646 RENAL VESICLE DEVELOPMENT 3 14 7.675e-05 0.0005494
647 METANEPHRIC MESENCHYME DEVELOPMENT 3 14 7.675e-05 0.0005494
648 CONVERGENT EXTENSION 3 14 7.675e-05 0.0005494
649 CRANIOFACIAL SUTURE MORPHOGENESIS 3 14 7.675e-05 0.0005494
650 RESPONSE TO LAMINAR FLUID SHEAR STRESS 3 14 7.675e-05 0.0005494
651 ENERGY RESERVE METABOLIC PROCESS 5 72 7.851e-05 0.0005612
652 ANGIOGENESIS 9 293 7.899e-05 0.0005637
653 REGULATION OF GENE EXPRESSION EPIGENETIC 8 229 8.213e-05 0.0005852
654 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 4 38 8.286e-05 0.0005895
655 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 5 73 8.388e-05 0.0005931
656 EMBRYONIC HEART TUBE DEVELOPMENT 5 73 8.388e-05 0.0005931
657 HIPPOCAMPUS DEVELOPMENT 5 73 8.388e-05 0.0005931
658 REGULATION OF PLASMA MEMBRANE ORGANIZATION 5 73 8.388e-05 0.0005931
659 REGULATION OF AXON GUIDANCE 4 39 9.189e-05 0.0006479
660 GLANDULAR EPITHELIAL CELL DIFFERENTIATION 4 39 9.189e-05 0.0006479
661 POSITIVE REGULATION OF ENDOTHELIAL CELL DIFFERENTIATION 3 15 9.551e-05 0.0006653
662 MESENCHYMAL TO EPITHELIAL TRANSITION 3 15 9.551e-05 0.0006653
663 REGULATION OF EPITHELIAL CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 3 15 9.551e-05 0.0006653
664 ENDOCARDIAL CUSHION FORMATION 3 15 9.551e-05 0.0006653
665 REGULATION OF MESODERM DEVELOPMENT 3 15 9.551e-05 0.0006653
666 REGULATION OF CELL PROLIFERATION INVOLVED IN HEART MORPHOGENESIS 3 15 9.551e-05 0.0006653
667 POSITIVE REGULATION OF T CELL APOPTOTIC PROCESS 3 15 9.551e-05 0.0006653
668 NEURAL CREST CELL DIFFERENTIATION 5 75 9.545e-05 0.0006653
669 POSITIVE REGULATION OF CELL MATRIX ADHESION 4 40 0.0001016 0.0007068
670 NEGATIVE REGULATION OF DEPHOSPHORYLATION 5 77 0.0001082 0.0007515
671 PROSTATE GLAND DEVELOPMENT 4 41 0.0001121 0.0007772
672 ESTABLISHMENT OR MAINTENANCE OF MONOPOLAR CELL POLARITY 3 16 0.000117 0.0008091
673 CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN HEART DEVELOPMENT 3 16 0.000117 0.0008091
674 NEGATIVE REGULATION OF PROTEIN BINDING 5 79 0.0001222 0.0008439
675 POSITIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 4 42 0.0001233 0.0008462
676 EPITHELIAL CELL MORPHOGENESIS 4 42 0.0001233 0.0008462
677 REGULATION OF HEART GROWTH 4 42 0.0001233 0.0008462
678 GENITALIA DEVELOPMENT 4 42 0.0001233 0.0008462
679 REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 7 181 0.0001236 0.000847
680 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 5 80 0.0001298 0.0008879
681 REGULATION OF HEMOPOIESIS 9 314 0.0001335 0.0009121
682 IMMUNE SYSTEM PROCESS 26 1984 0.0001354 0.0009211
683 MORPHOGENESIS OF AN EPITHELIAL SHEET 4 43 0.0001353 0.0009211
684 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 4 43 0.0001353 0.0009211
685 REGULATION OF PROTEIN SECRETION 10 389 0.0001376 0.0009335
686 REGULATION OF FIBROBLAST PROLIFERATION 5 81 0.0001376 0.0009335
687 POSITIVE REGULATION OF CELL CYCLE PROCESS 8 247 0.0001386 0.0009389
688 NEGATIVE REGULATION OF KIDNEY DEVELOPMENT 3 17 0.0001415 0.0009485
689 POSITIVE REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 3 17 0.0001415 0.0009485
690 DORSAL VENTRAL NEURAL TUBE PATTERNING 3 17 0.0001415 0.0009485
691 REGULATION OF STEM CELL POPULATION MAINTENANCE 3 17 0.0001415 0.0009485
692 MAMMARY GLAND ALVEOLUS DEVELOPMENT 3 17 0.0001415 0.0009485
693 MAMMARY GLAND LOBULE DEVELOPMENT 3 17 0.0001415 0.0009485
694 NEGATIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 3 17 0.0001415 0.0009485
695 LABYRINTHINE LAYER DEVELOPMENT 4 44 0.0001481 0.0009918
696 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 6 131 0.0001529 0.001021
697 NEGATIVE REGULATION OF BINDING 6 131 0.0001529 0.001021
698 EMBRYONIC PLACENTA DEVELOPMENT 5 83 0.0001545 0.00103
699 REGULATION OF CELL PROJECTION ORGANIZATION 12 558 0.0001581 0.001052
700 REGULATION OF NEURON DEATH 8 252 0.000159 0.001057
701 REGULATION OF LYMPHOCYTE DIFFERENTIATION 6 132 0.0001594 0.001058
702 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 16 926 0.0001616 0.001068
703 SUBSTANTIA NIGRA DEVELOPMENT 4 45 0.0001618 0.001068
704 EXOCRINE SYSTEM DEVELOPMENT 4 45 0.0001618 0.001068
705 REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 4 45 0.0001618 0.001068
706 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 10 397 0.0001623 0.00107
707 GLANDULAR EPITHELIAL CELL DEVELOPMENT 3 18 0.000169 0.001106
708 PERICARDIUM DEVELOPMENT 3 18 0.000169 0.001106
709 OSTEOBLAST DEVELOPMENT 3 18 0.000169 0.001106
710 POST ANAL TAIL MORPHOGENESIS 3 18 0.000169 0.001106
711 NOTOCHORD DEVELOPMENT 3 18 0.000169 0.001106
712 RESPONSE TO INORGANIC SUBSTANCE 11 479 0.0001706 0.001115
713 GUANOSINE CONTAINING COMPOUND METABOLIC PROCESS 4 46 0.0001764 0.001151
714 POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 7 192 0.000178 0.001158
715 REGULATION OF NEURON APOPTOTIC PROCESS 7 192 0.000178 0.001158
716 CELL GROWTH 6 135 0.0001802 0.001171
717 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 6 136 0.0001876 0.001216
718 GLIAL CELL DIFFERENTIATION 6 136 0.0001876 0.001216
719 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 4 47 0.0001919 0.001242
720 TISSUE REMODELING 5 87 0.0001928 0.001246
721 REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 3 19 0.0001998 0.001288
722 ENTEROENDOCRINE CELL DIFFERENTIATION 3 19 0.0001998 0.001288
723 REGULATION OF NEURON PROJECTION DEVELOPMENT 10 408 0.0002023 0.001302
724 PLACENTA DEVELOPMENT 6 138 0.0002031 0.001305
725 COLUMNAR CUBOIDAL EPITHELIAL CELL DEVELOPMENT 4 48 0.0002084 0.001336
726 POSITIVE REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 4 48 0.0002084 0.001336
727 CELLULAR RESPONSE TO ABIOTIC STIMULUS 8 263 0.0002128 0.001362
728 CELLULAR RESPONSE TO EXTERNAL STIMULUS 8 264 0.0002183 0.001393
729 AGING 8 264 0.0002183 0.001393
730 RESPONSE TO RADIATION 10 413 0.0002231 0.001422
731 REGULATION OF STEROID BIOSYNTHETIC PROCESS 4 49 0.0002258 0.001438
732 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 7 200 0.0002286 0.001453
733 POSITIVE REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 3 20 0.000234 0.001486
734 MULTICELLULAR ORGANISM REPRODUCTION 14 768 0.0002482 0.001573
735 SECRETION 12 588 0.0002557 0.001619
736 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 15 867 0.000259 0.001637
737 PROTEASOMAL PROTEIN CATABOLIC PROCESS 8 271 0.0002605 0.001645
738 REGULATION OF DNA BINDING 5 93 0.0002634 0.001661
739 HOMOTYPIC CELL CELL ADHESION 4 51 0.0002639 0.001662
740 REGULATION OF GENE SILENCING BY RNA 3 21 0.0002718 0.0017
741 CHONDROCYTE DEVELOPMENT 3 21 0.0002718 0.0017
742 ECTODERM DEVELOPMENT 3 21 0.0002718 0.0017
743 POSITIVE REGULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 3 21 0.0002718 0.0017
744 REGULATION OF POSTTRANSCRIPTIONAL GENE SILENCING 3 21 0.0002718 0.0017
745 REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 8 274 0.0002806 0.001752
746 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 5 95 0.0002908 0.001814
747 REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 6 148 0.0002963 0.001843
748 POSITIVE REGULATION OF CELL GROWTH 6 148 0.0002963 0.001843
749 MYELOID LEUKOCYTE DIFFERENTIATION 5 96 0.0003053 0.001897
750 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 4 53 0.0003063 0.001898
751 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 4 53 0.0003063 0.001898
752 NEGATIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 22 0.0003133 0.001931
753 DSRNA FRAGMENTATION 3 22 0.0003133 0.001931
754 EMBRYONIC PLACENTA MORPHOGENESIS 3 22 0.0003133 0.001931
755 PRODUCTION OF SMALL RNA INVOLVED IN GENE SILENCING BY RNA 3 22 0.0003133 0.001931
756 POSITIVE REGULATION OF PROTEIN SECRETION 7 211 0.0003165 0.001948
757 NEGATIVE REGULATION OF REPRODUCTIVE PROCESS 4 54 0.0003293 0.002021
758 REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 4 54 0.0003293 0.002021
759 POSITIVE REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 5 98 0.0003359 0.002054
760 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 5 98 0.0003359 0.002054
761 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 5 98 0.0003359 0.002054
762 REGULATION OF MUSCLE CELL DIFFERENTIATION 6 152 0.0003419 0.002088
763 PALLIUM DEVELOPMENT 6 153 0.0003541 0.002156
764 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 6 153 0.0003541 0.002156
765 POSITIVE REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 3 23 0.0003587 0.002176
766 SCF DEPENDENT PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 3 23 0.0003587 0.002176
767 POSITIVE REGULATION OF STEROID METABOLIC PROCESS 3 23 0.0003587 0.002176
768 LIMBIC SYSTEM DEVELOPMENT 5 100 0.0003688 0.002235
769 KERATINOCYTE DIFFERENTIATION 5 101 0.0003862 0.002334
770 REGULATION OF EXTENT OF CELL GROWTH 5 101 0.0003862 0.002334
771 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 6 156 0.0003927 0.00237
772 EMBRYONIC CAMERA TYPE EYE MORPHOGENESIS 3 24 0.0004082 0.00245
773 RESPONSE TO STEROL 3 24 0.0004082 0.00245
774 REGULATION OF ODONTOGENESIS 3 24 0.0004082 0.00245
775 ENDOTHELIAL CELL PROLIFERATION 3 24 0.0004082 0.00245
776 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 10 448 0.0004247 0.002547
777 CELLULAR GLUCAN METABOLIC PROCESS 4 58 0.0004335 0.002593
778 GLUCAN METABOLIC PROCESS 4 58 0.0004335 0.002593
779 ACTIN FILAMENT BASED PROCESS 10 450 0.0004398 0.002627
780 REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 4 59 0.0004629 0.00274
781 EPITHELIAL TUBE BRANCHING INVOLVED IN LUNG MORPHOGENESIS 3 25 0.0004618 0.00274
782 LUNG CELL DIFFERENTIATION 3 25 0.0004618 0.00274
783 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 3 25 0.0004618 0.00274
784 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 3 25 0.0004618 0.00274
785 EPITHELIAL CELL APOPTOTIC PROCESS 3 25 0.0004618 0.00274
786 REGULATION OF GLIAL CELL DIFFERENTIATION 4 59 0.0004629 0.00274
787 NEGATIVE REGULATION OF CELL DIVISION 4 60 0.0004936 0.002915
788 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 4 60 0.0004936 0.002915
789 POSITIVE REGULATION OF HEMOPOIESIS 6 163 0.0004958 0.002924
790 REGULATION OF T CELL DIFFERENTIATION 5 107 0.0005035 0.002965
791 NEGATIVE REGULATION OF GLIAL CELL DIFFERENTIATION 3 26 0.0005197 0.003045
792 REGULATION OF MESONEPHROS DEVELOPMENT 3 26 0.0005197 0.003045
793 MESODERMAL CELL DIFFERENTIATION 3 26 0.0005197 0.003045
794 REGULATION OF HORMONE METABOLIC PROCESS 3 26 0.0005197 0.003045
795 OVARIAN FOLLICLE DEVELOPMENT 4 61 0.0005258 0.003074
796 REGULATION OF CELL CYCLE ARREST 5 108 0.0005254 0.003074
797 POSITIVE REGULATION OF NUCLEAR DIVISION 4 62 0.0005594 0.003262
798 EMBRYONIC HEART TUBE MORPHOGENESIS 4 62 0.0005594 0.003262
799 CELLULAR RESPONSE TO HORMONE STIMULUS 11 552 0.000568 0.003308
800 REGULATION OF ENDOTHELIAL CELL DIFFERENTIATION 3 27 0.000582 0.003381
801 NEGATIVE REGULATION OF AXON GUIDANCE 3 27 0.000582 0.003381
802 NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY 6 170 0.0006188 0.00359
803 POSITIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 4 64 0.0006312 0.003653
804 RIBONUCLEOSIDE DIPHOSPHATE METABOLIC PROCESS 4 64 0.0006312 0.003653
805 POSITIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 3 28 0.000649 0.003751
806 REGULATION OF CELL SIZE 6 172 0.000658 0.003799
807 REGULATION OF PEPTIDASE ACTIVITY 9 392 0.0006775 0.003906
808 CELLULAR RESPONSE TO ALCOHOL 5 115 0.0006993 0.004027
809 SOMATIC STEM CELL POPULATION MAINTENANCE 4 66 0.0007093 0.004075
810 FOREBRAIN GENERATION OF NEURONS 4 66 0.0007093 0.004075
811 EPIDERMIS MORPHOGENESIS 3 29 0.0007207 0.004119
812 NEGATIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 3 29 0.0007207 0.004119
813 REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 3 29 0.0007207 0.004119
814 EMBRYONIC HINDLIMB MORPHOGENESIS 3 29 0.0007207 0.004119
815 RESPONSE TO CORTICOSTEROID 6 176 0.0007421 0.004237
816 SPECIFICATION OF SYMMETRY 5 117 0.0007561 0.004311
817 REGULATION OF CELL ACTIVATION 10 484 0.0007718 0.004395
818 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 6 178 0.0007871 0.004477
819 PROTEIN LOCALIZATION TO CYTOSKELETON 3 30 0.0007972 0.004496
820 SECRETION BY CELL 10 486 0.0007964 0.004496
821 SMOOTH MUSCLE CELL DIFFERENTIATION 3 30 0.0007972 0.004496
822 POSITIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 30 0.0007972 0.004496
823 REGULATION OF CELL JUNCTION ASSEMBLY 4 68 0.0007941 0.004496
824 ORGAN GROWTH 4 68 0.0007941 0.004496
825 MODULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 3 30 0.0007972 0.004496
826 POSITIVE REGULATION OF AXONOGENESIS 4 69 0.000839 0.004726
827 POSITIVE REGULATION OF CHEMOTAXIS 5 120 0.0008476 0.004769
828 PROTEIN TARGETING 9 406 0.0008683 0.004879
829 RESPONSE TO KETONE 6 182 0.0008835 0.004959
830 ADHERENS JUNCTION ORGANIZATION 4 71 0.0009342 0.005237
831 NEGATIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 3 32 0.0009653 0.005398
832 PATTERNING OF BLOOD VESSELS 3 32 0.0009653 0.005398
833 ENDOTHELIAL CELL DIFFERENTIATION 4 72 0.0009845 0.005499
834 RESPONSE TO METAL ION 8 333 0.00101 0.005637
835 STEROID HORMONE MEDIATED SIGNALING PATHWAY 5 125 0.001018 0.005674
836 RESPONSE TO VITAMIN D 3 33 0.001057 0.005884
837 CELLULAR RESPONSE TO NITROGEN COMPOUND 10 505 0.001065 0.005919
838 MYELOID CELL DIFFERENTIATION 6 189 0.001074 0.005963
839 REGULATION OF CELLULAR COMPONENT SIZE 8 337 0.001091 0.006042
840 REGULATION OF STEROID METABOLIC PROCESS 4 74 0.001091 0.006042
841 RESPONSE TO FLUID SHEAR STRESS 3 34 0.001154 0.006371
842 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION 3 34 0.001154 0.006371
843 NEURAL TUBE PATTERNING 3 34 0.001154 0.006371
844 REGULATION OF MEMBRANE POTENTIAL 8 343 0.001221 0.006729
845 CELL CYCLE CHECKPOINT 6 194 0.001228 0.006762
846 NEGATIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 5 131 0.001255 0.006872
847 BONE REMODELING 3 35 0.001257 0.006872
848 REGULATION OF GLYCOGEN METABOLIC PROCESS 3 35 0.001257 0.006872
849 REGULATION OF GASTRULATION 3 35 0.001257 0.006872
850 EMBRYONIC CAMERA TYPE EYE DEVELOPMENT 3 35 0.001257 0.006872
851 RESPONSE TO IRON ION 3 35 0.001257 0.006872
852 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 4 77 0.001265 0.006909
853 CELLULAR PROTEIN COMPLEX ASSEMBLY 8 346 0.00129 0.007036
854 MICROTUBULE BASED PROCESS 10 522 0.001364 0.007394
855 POSITIVE REGULATION OF PROTEIN ACETYLATION 3 36 0.001365 0.007394
856 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 3 36 0.001365 0.007394
857 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 3 36 0.001365 0.007394
858 CORTICAL CYTOSKELETON ORGANIZATION 3 36 0.001365 0.007394
859 POSITIVE CHEMOTAXIS 3 36 0.001365 0.007394
860 DENDRITE DEVELOPMENT 4 79 0.001392 0.00752
861 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 4 79 0.001392 0.00752
862 POLYSACCHARIDE METABOLIC PROCESS 4 80 0.001458 0.007852
863 POSITIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION 4 80 0.001458 0.007852
864 CELLULAR RESPONSE TO MECHANICAL STIMULUS 4 80 0.001458 0.007852
865 NEGATIVE REGULATION OF GLIOGENESIS 3 37 0.001479 0.007928
866 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO CELL PERIPHERY 3 37 0.001479 0.007928
867 GLIAL CELL MIGRATION 3 37 0.001479 0.007928
868 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 3 37 0.001479 0.007928
869 DNA TEMPLATED TRANSCRIPTION INITIATION 6 202 0.001509 0.008082
870 RESPONSE TO EXTRACELLULAR STIMULUS 9 441 0.001542 0.008246
871 MUSCLE ORGAN DEVELOPMENT 7 277 0.001568 0.008375
872 NEGATIVE REGULATION OF AXON EXTENSION 3 38 0.001599 0.008509
873 CELLULAR RESPONSE TO DSRNA 3 38 0.001599 0.008509
874 REGULATION OF CHROMOSOME ORGANIZATION 7 278 0.0016 0.008509
875 NEGATIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 4 82 0.001597 0.008509
876 MITOTIC CELL CYCLE CHECKPOINT 5 139 0.001632 0.008657
877 GENE SILENCING BY RNA 5 139 0.001632 0.008657
878 RESPONSE TO LIGHT STIMULUS 7 280 0.001667 0.008833
879 ORGAN REGENERATION 4 83 0.00167 0.008842
880 REGULATION OF HOMEOSTATIC PROCESS 9 447 0.001691 0.008941
881 NEGATIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 3 39 0.001724 0.009075
882 NEGATIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 3 39 0.001724 0.009075
883 REGULATION OF CELL ADHESION MEDIATED BY INTEGRIN 3 39 0.001724 0.009075
884 PLATELET AGGREGATION 3 39 0.001724 0.009075
885 NUCLEOSIDE DIPHOSPHATE METABOLIC PROCESS 4 84 0.001746 0.009178
886 PLATELET ACTIVATION 5 142 0.001792 0.009413
887 POSITIVE REGULATION OF CHROMATIN MODIFICATION 4 85 0.001823 0.009565
888 RESPONSE TO MECHANICAL STIMULUS 6 210 0.001837 0.009627
889 REGULATION OF MEIOTIC CELL CYCLE 3 40 0.001856 0.009702
890 ENDOCRINE PANCREAS DEVELOPMENT 3 40 0.001856 0.009702
891 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 5 144 0.001906 0.009952
NumGOOverlapSizeP ValueAdj. P Value
1 BETA CATENIN BINDING 18 84 2.528e-23 2.349e-20
2 FRIZZLED BINDING 14 36 1.553e-22 7.211e-20
3 TRANSFORMING GROWTH FACTOR BETA RECEPTOR BINDING 14 50 3.573e-20 1.106e-17
4 ENZYME BINDING 47 1737 1.736e-19 4.032e-17
5 PROTEIN DOMAIN SPECIFIC BINDING 30 624 6.835e-19 1.27e-16
6 RECEPTOR BINDING 42 1476 4.841e-18 7.496e-16
7 KINASE BINDING 28 606 3.388e-17 3.934e-15
8 WNT ACTIVATED RECEPTOR ACTIVITY 10 22 2.977e-17 3.934e-15
9 WNT PROTEIN BINDING 10 31 1.95e-15 2.013e-13
10 I SMAD BINDING 7 11 8.539e-14 7.933e-12
11 SMAD BINDING 11 72 6.071e-13 5.127e-11
12 GAMMA CATENIN BINDING 6 12 4.081e-11 3.159e-09
13 G PROTEIN COUPLED RECEPTOR BINDING 15 259 5.772e-11 4.125e-09
14 PDZ DOMAIN BINDING 10 90 1.861e-10 1.235e-08
15 GROWTH FACTOR ACTIVITY 12 160 2.757e-10 1.708e-08
16 UBIQUITIN LIKE PROTEIN LIGASE BINDING 14 264 8.302e-10 4.782e-08
17 CYTOKINE ACTIVITY 13 219 8.75e-10 4.782e-08
18 CYTOKINE RECEPTOR BINDING 14 271 1.166e-09 6.02e-08
19 PROTEIN PHOSPHATASE TYPE 2A REGULATOR ACTIVITY 6 21 2.292e-09 1.12e-07
20 IONOTROPIC GLUTAMATE RECEPTOR BINDING 6 23 4.221e-09 1.961e-07
21 PROTEIN DIMERIZATION ACTIVITY 26 1149 5.029e-09 2.225e-07
22 MOLECULAR FUNCTION REGULATOR 28 1353 8.149e-09 3.43e-07
23 RECEPTOR SIGNALING PROTEIN ACTIVITY 11 172 8.491e-09 3.43e-07
24 RECEPTOR SERINE THREONINE KINASE BINDING 5 15 2.224e-08 8.609e-07
25 RECEPTOR AGONIST ACTIVITY 5 16 3.219e-08 1.196e-06
26 MACROMOLECULAR COMPLEX BINDING 27 1399 6.778e-08 2.422e-06
27 GLUTAMATE RECEPTOR BINDING 6 37 9.066e-08 3.119e-06
28 PROTEIN HETERODIMERIZATION ACTIVITY 15 468 1.721e-07 5.71e-06
29 KINASE ACTIVITY 20 842 1.783e-07 5.712e-06
30 PROTEIN COMPLEX BINDING 21 935 2.143e-07 6.637e-06
31 IDENTICAL PROTEIN BINDING 24 1209 2.511e-07 7.524e-06
32 SIGNAL TRANSDUCER ACTIVITY 29 1731 4.088e-07 1.187e-05
33 PROTEIN SERINE THREONINE KINASE ACTIVITY 14 445 5.701e-07 1.605e-05
34 GUANYLATE KINASE ACTIVITY 4 12 6.281e-07 1.716e-05
35 PHOSPHATASE BINDING 9 162 6.706e-07 1.763e-05
36 CADHERIN BINDING 5 28 6.831e-07 1.763e-05
37 TRANSCRIPTION FACTOR BINDING 15 524 7.225e-07 1.814e-05
38 ARMADILLO REPEAT DOMAIN BINDING 4 13 9.03e-07 2.208e-05
39 RECEPTOR ACTIVATOR ACTIVITY 5 32 1.373e-06 3.27e-05
40 PROTEIN KINASE ACTIVITY 16 640 1.777e-06 4.126e-05
41 REGULATORY REGION NUCLEIC ACID BINDING 18 818 2.337e-06 5.169e-05
42 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 20 992 2.306e-06 5.169e-05
43 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 6 64 2.557e-06 5.523e-05
44 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE ACTIVITY 4 17 2.95e-06 6.228e-05
45 RECEPTOR REGULATOR ACTIVITY 5 45 7.817e-06 0.0001614
46 R SMAD BINDING 4 23 1.067e-05 0.0002154
47 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 21 1199 1.111e-05 0.0002196
48 NUCLEOTIDE KINASE ACTIVITY 4 24 1.274e-05 0.0002466
49 PHOSPHATASE REGULATOR ACTIVITY 6 87 1.536e-05 0.0002912
50 CORE PROMOTER PROXIMAL REGION DNA BINDING 11 371 1.723e-05 0.0003201
51 PROTEIN C TERMINUS BINDING 8 186 1.878e-05 0.0003355
52 CELL ADHESION MOLECULE BINDING 8 186 1.878e-05 0.0003355
53 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 6 92 2.116e-05 0.0003709
54 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 10 328 3.338e-05 0.0005742
55 PROTEIN HOMODIMERIZATION ACTIVITY 15 722 3.408e-05 0.0005756
56 GLYCOPROTEIN BINDING 6 101 3.597e-05 0.0005967
57 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 6 104 4.243e-05 0.0006915
58 CO SMAD BINDING 3 12 4.68e-05 0.0007496
59 ION CHANNEL BINDING 6 111 6.116e-05 0.0009629
60 ENZYME REGULATOR ACTIVITY 17 959 7.258e-05 0.001124
61 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 8 226 7.491e-05 0.001141
62 PROTEIN PHOSPHATASE BINDING 6 120 9.436e-05 0.001414
63 PHOSPHOTRANSFERASE ACTIVITY PHOSPHATE GROUP AS ACCEPTOR 4 40 0.0001016 0.001499
64 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 7 178 0.0001114 0.001617
65 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 13 629 0.0001237 0.001768
66 NUCLEOBASE CONTAINING COMPOUND KINASE ACTIVITY 4 48 0.0002084 0.002933
67 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 12 588 0.0002557 0.003546
68 CHROMATIN BINDING 10 435 0.000337 0.004604
69 PROTEIN PHOSPHORYLATED AMINO ACID BINDING 3 24 0.0004082 0.005495
70 TRANSCRIPTION COREPRESSOR ACTIVITY 7 221 0.0004183 0.005551
71 PHOSPHOPROTEIN BINDING 4 60 0.0004936 0.006459
72 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 8 315 0.0007058 0.009106
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 38 1151 2.218e-18 1.296e-15
2 WNT SIGNALOSOME 8 11 2.468e-16 7.206e-14
3 APICAL JUNCTION COMPLEX 15 128 1.847e-15 3.596e-13
4 CELL CELL JUNCTION 21 383 1.713e-14 2.501e-12
5 ANCHORING JUNCTION 23 489 2.225e-14 2.599e-12
6 PHOSPHATASE COMPLEX 10 48 2.637e-13 2.567e-11
7 PROTEIN PHOSPHATASE TYPE 2A COMPLEX 7 20 1.917e-11 1.599e-09
8 CYTOPLASMIC VESICLE PART 21 601 9.247e-11 6.751e-09
9 BETA CATENIN DESTRUCTION COMPLEX 6 14 1.313e-10 8.521e-09
10 EXTRACELLULAR MATRIX 17 426 9.229e-10 5.39e-08
11 CELL CELL ADHERENS JUNCTION 8 54 1.251e-09 6.641e-08
12 NEURON PROJECTION 24 942 2.191e-09 1.066e-07
13 CELL CORTEX 13 238 2.413e-09 1.084e-07
14 CYTOSKELETON 35 1967 3.622e-09 1.511e-07
15 TRANSCRIPTION FACTOR COMPLEX 14 298 3.965e-09 1.544e-07
16 CELL PROJECTION 33 1786 4.607e-09 1.682e-07
17 INTRACELLULAR VESICLE 27 1259 7.542e-09 2.591e-07
18 NEURON PART 27 1265 8.341e-09 2.706e-07
19 VESICLE MEMBRANE 17 512 1.44e-08 4.426e-07
20 LATERAL PLASMA MEMBRANE 7 50 2.123e-08 5.904e-07
21 CELL SUBSTRATE JUNCTION 15 398 2.076e-08 5.904e-07
22 CYTOPLASMIC REGION 13 287 2.27e-08 6.026e-07
23 ENDOCYTIC VESICLE MEMBRANE 10 152 3.178e-08 7.424e-07
24 CELL SURFACE 20 757 3.166e-08 7.424e-07
25 CELL LEADING EDGE 14 350 3.031e-08 7.424e-07
26 EXTRACELLULAR SPACE 27 1376 4.824e-08 1.084e-06
27 ENDOCYTIC VESICLE 12 256 5.584e-08 1.208e-06
28 LAMELLIPODIUM 10 172 1.024e-07 2.135e-06
29 PLASMA MEMBRANE REGION 21 929 1.926e-07 3.879e-06
30 AXON 14 418 2.688e-07 5.224e-06
31 PROTEINACEOUS EXTRACELLULAR MATRIX 13 356 2.773e-07 5.224e-06
32 MEMBRANE REGION 23 1134 3.202e-07 5.844e-06
33 CELL BODY 15 494 3.434e-07 6.076e-06
34 SOMATODENDRITIC COMPARTMENT 17 650 4.386e-07 7.534e-06
35 PLASMA MEMBRANE PROTEIN COMPLEX 15 510 5.14e-07 8.577e-06
36 SYNAPSE 18 754 7.335e-07 1.19e-05
37 CELL PROJECTION PART 20 946 1.114e-06 1.758e-05
38 CYTOSKELETAL PART 25 1436 1.542e-06 2.329e-05
39 MEMBRANE MICRODOMAIN 11 288 1.555e-06 2.329e-05
40 GOLGI LUMEN 7 94 1.744e-06 2.546e-05
41 MICROTUBULE CYTOSKELETON 21 1068 1.85e-06 2.635e-05
42 EXCITATORY SYNAPSE 9 197 3.399e-06 4.726e-05
43 POSTSYNAPSE 12 378 3.501e-06 4.755e-05
44 SYNAPSE PART 15 610 4.688e-06 6.222e-05
45 CHROMOSOME 18 880 6.443e-06 8.362e-05
46 INTERCALATED DISC 5 51 1.46e-05 0.0001814
47 PLASMA MEMBRANE RAFT 6 86 1.437e-05 0.0001814
48 NEURONAL POSTSYNAPTIC DENSITY 5 53 1.766e-05 0.0002149
49 NUCLEAR CHROMOSOME 13 523 1.883e-05 0.0002244
50 EXTRINSIC COMPONENT OF PLASMA MEMBRANE 7 136 2.013e-05 0.0002351
51 DENDRITE 12 451 2.064e-05 0.0002364
52 CYTOPLASMIC MICROTUBULE 5 57 2.527e-05 0.0002838
53 PERINUCLEAR REGION OF CYTOPLASM 14 642 3.759e-05 0.0004142
54 CELL CELL CONTACT ZONE 5 64 4.448e-05 0.000481
55 BASOLATERAL PLASMA MEMBRANE 8 211 4.623e-05 0.0004909
56 CLATHRIN COATED ENDOCYTIC VESICLE 5 65 4.795e-05 0.0005001
57 APICAL PART OF CELL 10 361 7.452e-05 0.0007548
58 NUCLEAR CHROMATIN 9 291 7.497e-05 0.0007548
59 CHROMATIN 11 441 8.261e-05 0.0008177
60 ACTIN CYTOSKELETON 11 444 8.773e-05 0.0008539
61 CELL CORTEX PART 6 119 9.009e-05 0.0008625
62 PLASMA MEMBRANE RECEPTOR COMPLEX 7 175 0.0001002 0.0009437
63 MICROTUBULE ORGANIZING CENTER 13 623 0.0001125 0.001043
64 CORTICAL CYTOSKELETON 5 81 0.0001376 0.001256
65 EXTRINSIC COMPONENT OF MEMBRANE 8 252 0.000159 0.001429
66 CATALYTIC COMPLEX 17 1038 0.0001883 0.001666
67 IONOTROPIC GLUTAMATE RECEPTOR COMPLEX 4 47 0.0001919 0.001673
68 CLATHRIN COATED ENDOCYTIC VESICLE MEMBRANE 4 48 0.0002084 0.00179
69 PLATELET ALPHA GRANULE LUMEN 4 55 0.0003534 0.002991
70 RNA POLYMERASE II TRANSCRIPTION FACTOR COMPLEX 5 101 0.0003862 0.003222
71 CLATHRIN COATED VESICLE 6 157 0.0004063 0.003342
72 CORTICAL ACTIN CYTOSKELETON 4 58 0.0004335 0.003516
73 MYELIN SHEATH 6 168 0.0005815 0.00464
74 COATED VESICLE 7 234 0.000588 0.00464
75 SUPRAMOLECULAR FIBER 12 670 0.0008166 0.006359
76 MICROTUBULE 9 405 0.0008533 0.006557
77 ACTIN FILAMENT 4 70 0.0008857 0.006631
78 CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 3 31 0.0008787 0.006631
79 RECEPTOR COMPLEX 8 327 0.000899 0.006646
80 HISTONE METHYLTRANSFERASE COMPLEX 4 71 0.0009342 0.006819
81 SPINDLE POLE 5 126 0.001055 0.007608
82 NUCLEAR TRANSCRIPTION FACTOR COMPLEX 5 127 0.001093 0.007786
83 PLATELET ALPHA GRANULE 4 75 0.001147 0.00807
84 GOLGI APPARATUS 19 1445 0.001185 0.008242
85 MEMBRANE PROTEIN COMPLEX 15 1020 0.001379 0.009472
86 DENDRITIC SHAFT 3 37 0.001479 0.009928
87 ENDOPLASMIC RETICULUM LUMEN 6 201 0.001472 0.009928

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04390_Hippo_signaling_pathway 122 154 3.197e-289 5.754e-287
2 hsa04310_Wnt_signaling_pathway 46 151 7.67e-68 6.903e-66
3 hsa04916_Melanogenesis 28 101 1.709e-39 1.025e-37
4 hsa04350_TGF.beta_signaling_pathway 24 85 4.244e-34 1.91e-32
5 hsa04340_Hedgehog_signaling_pathway 20 56 6.518e-31 2.346e-29
6 hsa04530_Tight_junction 20 133 1.56e-22 4.681e-21
7 hsa04520_Adherens_junction 16 73 5.24e-21 1.347e-19
8 hsa04110_Cell_cycle 16 128 7.041e-17 1.584e-15
9 hsa04114_Oocyte_meiosis 13 114 2.174e-13 4.348e-12
10 hsa04151_PI3K_AKT_signaling_pathway 18 351 4.617e-12 8.311e-11
11 hsa04144_Endocytosis 11 203 4.719e-08 7.722e-07
12 hsa04510_Focal_adhesion 10 200 4.165e-07 6.247e-06
13 hsa03015_mRNA_surveillance_pathway 7 83 7.475e-07 1.035e-05
14 hsa04115_p53_signaling_pathway 6 69 3.987e-06 5.127e-05
15 hsa04710_Circadian_rhythm_._mammal 4 23 1.067e-05 0.000128
16 hsa04722_Neurotrophin_signaling_pathway 7 127 1.29e-05 0.0001451
17 hsa04810_Regulation_of_actin_cytoskeleton 8 214 5.108e-05 0.0005408
18 hsa04670_Leukocyte_transendothelial_migration 6 117 8.2e-05 0.00082
19 hsa04910_Insulin_signaling_pathway 6 138 0.0002031 0.001924
20 hsa04010_MAPK_signaling_pathway 7 268 0.001298 0.01168
21 hsa04330_Notch_signaling_pathway 3 47 0.002953 0.02531
22 hsa04720_Long.term_potentiation 3 70 0.009007 0.07049
23 hsa04730_Long.term_depression 3 70 0.009007 0.07049
24 hsa04630_Jak.STAT_signaling_pathway 4 155 0.01505 0.1129
25 hsa04012_ErbB_signaling_pathway 3 87 0.01619 0.1166
26 hsa04270_Vascular_smooth_muscle_contraction 3 116 0.03412 0.2362
27 hsa04380_Osteoclast_differentiation 3 128 0.04363 0.2909
28 hsa04660_T_cell_receptor_signaling_pathway 2 108 0.1409 0.906
29 hsa04120_Ubiquitin_mediated_proteolysis 2 139 0.2081 1
30 hsa04145_Phagosome 2 156 0.2463 1
31 hsa04062_Chemokine_signaling_pathway 2 189 0.3207 1
32 hsa04014_Ras_signaling_pathway 2 236 0.4231 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1 LINC00982 hsa-miR-15b-5p;hsa-miR-186-5p;hsa-miR-192-3p;hsa-miR-193b-3p;hsa-miR-193b-5p;hsa-miR-194-5p;hsa-miR-197-3p;hsa-miR-224-3p;hsa-miR-365a-3p;hsa-miR-550a-5p 10 WTIP Sponge network -0.089 0.85759 -0.083 0.6902 0.506
2

HCG11

 hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-93-5p 10 TGFBR2 Sponge network -0.781 0 -0.523 3.0E-5 0.472
3

HCG11

 hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-362-3p;hsa-miR-455-5p;hsa-miR-618;hsa-miR-877-5p;hsa-miR-93-5p 16 BMPR2 Sponge network -0.781 0 -0.736 0 0.47
4 GAS5 hsa-let-7a-2-3p;hsa-let-7g-3p;hsa-miR-101-3p;hsa-miR-125b-5p;hsa-miR-139-5p;hsa-miR-140-5p;hsa-miR-144-3p;hsa-miR-27b-3p;hsa-miR-345-5p;hsa-miR-590-3p 10 BBC3 Sponge network 1.966 0 0.805 0 0.454
5

RP11-12A2.3

 hsa-miR-1301-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-30d-5p;hsa-miR-338-3p;hsa-miR-877-5p;hsa-miR-93-3p 13 DLG2 Sponge network -4.779 0 -1.947 0 0.452
6

MAGI2-AS3

 hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-92a-3p;hsa-miR-93-5p 11 TGFBR2 Sponge network -1.801 0 -0.523 3.0E-5 0.428
7

MAGI2-AS3

 hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-30d-5p;hsa-miR-362-3p;hsa-miR-532-5p;hsa-miR-769-5p;hsa-miR-877-5p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-93-5p 18 BMPR2 Sponge network -1.801 0 -0.736 0 0.408
8 RP11-175O19.4 hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-22-3p;hsa-miR-28-5p;hsa-miR-30c-5p;hsa-miR-30e-5p;hsa-miR-328-3p;hsa-miR-378a-3p;hsa-miR-455-3p;hsa-miR-505-5p 10 YWHAZ Sponge network 0.743 0 0.521 0 0.405
9

RP11-166D19.1

 hsa-miR-106b-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-330-5p;hsa-miR-484;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-92a-3p;hsa-miR-940 15 FZD4 Sponge network -0.244 0.28835 -0.346 0.01097 0.384
10 RP11-54O7.3 hsa-miR-107;hsa-miR-140-3p;hsa-miR-15b-5p;hsa-miR-192-3p;hsa-miR-193b-3p;hsa-miR-193b-5p;hsa-miR-194-5p;hsa-miR-224-3p;hsa-miR-550a-5p;hsa-miR-589-5p 10 WTIP Sponge network -3.012 0 -0.083 0.6902 0.377
11

LDLRAD4-AS1

 hsa-miR-1301-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-3127-5p;hsa-miR-421;hsa-miR-93-3p 12 DLG2 Sponge network -3.366 0 -1.947 0 0.374
12 LINC00238 hsa-miR-1301-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-338-3p;hsa-miR-93-3p 10 DLG2 Sponge network -4.997 0 -1.947 0 0.37
13

RP11-12A2.3

 hsa-miR-106b-5p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-30d-5p;hsa-miR-671-5p;hsa-miR-877-5p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-93-5p 15 BMPR2 Sponge network -4.779 0 -0.736 0 0.362
14

MAGI2-AS3

 hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-9-5p;hsa-miR-92a-3p;hsa-miR-93-5p 13 CCND1 Sponge network -1.801 0 -0.902 1.0E-5 0.359
15

SOCS2-AS1

 hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-532-5p;hsa-miR-671-5p;hsa-miR-93-3p;hsa-miR-93-5p 12 BMPR2 Sponge network -0.984 3.0E-5 -0.736 0 0.355
16

RP11-166D19.1

 hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-532-5p;hsa-miR-590-5p;hsa-miR-618;hsa-miR-877-5p;hsa-miR-92a-3p;hsa-miR-93-3p 17 BMPR2 Sponge network -0.244 0.28835 -0.736 0 0.348
17

SOCS2-AS1

 hsa-miR-103a-3p;hsa-miR-140-3p;hsa-miR-146b-5p;hsa-miR-151a-3p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-181b-5p;hsa-miR-185-5p;hsa-miR-301a-3p;hsa-miR-425-5p;hsa-miR-532-5p;hsa-miR-93-5p 12 TEAD1 Sponge network -0.984 3.0E-5 -0.192 0.10455 0.336
18 CASC2 hsa-miR-130b-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-362-3p;hsa-miR-532-5p;hsa-miR-877-5p;hsa-miR-92a-3p;hsa-miR-93-5p 12 BMPR2 Sponge network -0.596 0.00187 -0.736 0 0.327
19

RP11-166D19.1

 hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-590-5p;hsa-miR-92a-3p 11 TGFBR2 Sponge network -0.244 0.28835 -0.523 3.0E-5 0.324
20

RP11-12A2.3

 hsa-miR-103a-3p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-301a-3p;hsa-miR-425-5p;hsa-miR-93-5p 10 TEAD1 Sponge network -4.779 0 -0.192 0.10455 0.323
21

MAGI2-AS3

 hsa-miR-1301-3p;hsa-miR-148b-3p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-30d-5p;hsa-miR-3127-5p;hsa-miR-769-3p;hsa-miR-769-5p;hsa-miR-877-5p;hsa-miR-93-3p 14 DLG2 Sponge network -1.801 0 -1.947 0 0.298
22 RP11-289F5.1 hsa-miR-1301-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-769-3p 10 DLG2 Sponge network -6.122 0 -1.947 0 0.268
23

LDLRAD4-AS1

 hsa-miR-106b-5p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-93-3p;hsa-miR-93-5p 10 BMPR2 Sponge network -3.366 0 -0.736 0 0.263
24

RP11-166D19.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-425-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-92a-3p;hsa-miR-942-5p 16 CCND1 Sponge network -0.244 0.28835 -0.902 1.0E-5 0.253

Quest ID: e319119d09e53e0b1b953647d12eedb7