Visible node/edge number:
Node colors:
Node labels:

show label of nodes with degree >=

Node sizes:
Edge colors:
Edge widths factor:
Layout:

gravity >=

edgeLength =

GRN in network:

Notice: IE browser need to manually refresh (F5) this page after resetting the network.

This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-21-5p AKT2 1.75 0 -0.01 0.9227 miRNAWalker2 validate -0.15 0.00352 NA
2 hsa-miR-29b-3p AKT2 -0.23 0.36746 -0.01 0.9227 MirTarget -0.14 0.00022 26512921; 26564501; 24076586 MicroRNA 29B mir 29b regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3;The expression of miR-29b was significantly upregualted by cisplatin treatmentwhile its target gene AKT2 was downregulated;Furthermore a feed-back loop comprising of c-Myc miR-29 family and Akt2 were found in myeloid leukemogenesis
3 hsa-miR-106b-5p AKT3 1.71 0 -0.75 0.06936 miRNATAP -0.37 7.0E-5 NA
4 hsa-miR-107 AKT3 0.9 5.0E-5 -0.75 0.06936 PITA; miRanda -0.6 0 NA
5 hsa-miR-15b-5p AKT3 1.62 0 -0.75 0.06936 miRNATAP -0.36 0.00041 NA
6 hsa-miR-16-5p AKT3 1.01 1.0E-5 -0.75 0.06936 miRNAWalker2 validate; miRTarBase; miRNATAP -0.47 0.00031 NA
7 hsa-miR-17-3p AKT3 1.31 0 -0.75 0.06936 miRNATAP -0.52 0 NA
8 hsa-miR-17-5p AKT3 1.66 0 -0.75 0.06936 TargetScan; miRNATAP -0.28 0.0027 NA
9 hsa-miR-29a-3p AKT3 -0.11 0.61501 -0.75 0.06936 miRNATAP -0.41 0.00212 NA
10 hsa-miR-29b-3p AKT3 -0.23 0.36746 -0.75 0.06936 miRNATAP -0.34 0.00361 26512921 MicroRNA 29B mir 29b regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3
11 hsa-miR-32-3p AKT3 0.58 0.11837 -0.75 0.06936 mirMAP -0.32 0.00023 NA
12 hsa-miR-320b AKT3 1.11 0.0005 -0.75 0.06936 PITA; miRanda; miRNATAP -0.26 0.0039 NA
13 hsa-miR-335-3p AKT3 2.52 0 -0.75 0.06936 mirMAP -0.22 0.00074 NA
14 hsa-miR-33a-3p AKT3 0.35 0.32171 -0.75 0.06936 mirMAP -0.38 2.0E-5 NA
15 hsa-miR-362-3p AKT3 -0.03 0.91378 -0.75 0.06936 miRanda -0.38 4.0E-5 NA
16 hsa-miR-362-5p AKT3 -0.35 0.35491 -0.75 0.06936 PITA; TargetScan; miRNATAP -0.23 0.00253 NA
17 hsa-miR-501-3p AKT3 0.73 0.02704 -0.75 0.06936 miRNATAP -0.39 1.0E-5 NA
18 hsa-miR-502-3p AKT3 -0.16 0.55747 -0.75 0.06936 miRNATAP -0.5 0 NA
19 hsa-miR-505-3p AKT3 0.83 0.00112 -0.75 0.06936 mirMAP -0.35 0.00235 22051041 We also find that Akt3 correlate inversely with miR-505 modulates drug sensitivity in MCF7-ADR
20 hsa-miR-548v AKT3 -0.16 0.70867 -0.75 0.06936 miRNATAP -0.27 0.00031 NA
21 hsa-miR-577 AKT3 0.91 0.22561 -0.75 0.06936 mirMAP -0.23 0 NA
22 hsa-miR-616-5p AKT3 0.83 0.03478 -0.75 0.06936 mirMAP -0.27 0.00041 NA
23 hsa-miR-429 ANGPT1 1.4 0.009 -0.53 0.28334 miRanda -0.3 0 NA
24 hsa-miR-129-5p ANGPT2 -2.57 0 1.7 0 MirTarget; miRanda -0.13 0.00318 NA
25 hsa-miR-145-5p ANGPT2 -1.75 2.0E-5 1.7 0 MirTarget; miRNATAP -0.22 0.00012 24384875; 27570490 miR 145 functions as tumor suppressor and targets two oncogenes ANGPT2 and NEDD9 in renal cell carcinoma; We further validated those miR-145 targets two oncogenes ANGPT2 and NEDD9 in RCC;MiR 145 functions as a tumor suppressor via regulating angiopoietin 2 in pancreatic cancer cells; The direct action of miR-145 on Ang-2 was predicted by TargetScan and confirmed by luciferase report assay; The expression level of miR-145 was significantly lower and the expression levels of Ang-2 mRNA and protein was significantly higher in the more aggressive pancreatic cancer cells MiaPaCa-2 and Panc-1 when compared to that in BxPC3 cells; Overexpression of miR-145 in the BxPC3 MiaPaCa-2 and Panc-1 cells suppressed the cell invasion and colony formation ability and the expression level of Ang-2 protein in MiaPaCa-2 and Panc-1 cells was also suppressed after pre-miR-145 transfection; Intratumoral delivery of miR-145 inhibited the growth of pancreatic cancer xenografts and angiogenesis in vivo and also suppressed the expression level of angiopoietin-2 protein; MiR-145 functions as a tumor suppressor in pancreatic cancer cells by targeting Ang-2 for translation repression and thus suppresses pancreatic cancer cell invasion and growth which suggests that restoring of miR-145 may be a potential therapeutic target for pancreatic cancer
26 hsa-miR-664a-3p ANGPT2 -0.83 0.00014 1.7 0 mirMAP -0.37 0.00076 NA
27 hsa-miR-10b-5p ATF2 -0.3 0.31239 -0.02 0.89844 MirTarget; miRNATAP -0.13 0.00068 NA
28 hsa-miR-126-5p ATF2 0.42 0.07532 -0.02 0.89844 mirMAP -0.15 0.00299 NA
29 hsa-miR-212-3p ATF2 0.96 0.00133 -0.02 0.89844 miRNATAP -0.14 0.00026 NA
30 hsa-miR-590-3p ATF2 1.12 0.00016 -0.02 0.89844 MirTarget; miRanda; mirMAP; miRNATAP -0.12 0.00263 NA
31 hsa-miR-342-3p ATF6B 0.32 0.26915 0.49 0.0038 miRanda -0.15 0.00029 NA
32 hsa-miR-15b-3p BCL2 1.76 0 -1.09 0.00317 mirMAP -0.24 0.00334 25594541; 26915294; 26884837; 18449891 MicroRNAs miRNAs encoded by the miR-15 cluster are known to induce G1 arrest and apoptosis by targeting G1 checkpoints and the anti-apoptotic B cell lymphoma 2 BCL-2 gene;As a result transcript levels of the tumor-suppressive miR-15 and let-7 families increased which targeted and decreased the expression of the crucial prosurvival genes BCL-2 and BCL-XL respectively;MiR 15b mediates liver cancer cells proliferation through targeting BCL 2; MiR-15b overexpression downregulated BCL2 mRNA and protein expression obviously P < 0.05; On the contrary miR-15b inhibitor transfection markedly reduced miR-15b expression in liver cancer cells P < 0.05 promoted tumor cell proliferation and increased BCL2 mRNA and protein expression; MiR-15b can inhibit HepG2 cell proliferation and down-regulate BCL2 mRNA and protein expression;miR 15b and miR 16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells; The downregulation of miR-15b and miR-16 in SGC7901/VCR cells was concurrent with the upregulation of Bcl-2 protein; Taken together our findings suggest that miR-15b and miR-16 could play a role in the development of MDR in gastric cancer cells at least in part by modulation of apoptosis via targeting BCL2
33 hsa-miR-16-2-3p BCL2 1.8 0 -1.09 0.00317 mirMAP -0.26 0.0023 NA
34 hsa-miR-200a-5p BCL2 1.5 0.00264 -1.09 0.00317 mirMAP -0.21 5.0E-5 NA
35 hsa-miR-200b-3p BCL2 0.97 0.0595 -1.09 0.00317 miRNAWalker2 validate; miRTarBase; TargetScan; mirMAP -0.18 0.00034 NA
36 hsa-miR-200b-5p BCL2 0.97 0.05305 -1.09 0.00317 mirMAP -0.21 0.00019 NA
37 hsa-miR-200c-3p BCL2 1.28 0.0037 -1.09 0.00317 miRNAWalker2 validate; miRTarBase; mirMAP -0.23 0.00013 NA
38 hsa-miR-20a-3p BCL2 1.14 0.00045 -1.09 0.00317 mirMAP -0.22 0.00669 NA
39 hsa-miR-21-5p BCL2 1.75 0 -1.09 0.00317 miRNAWalker2 validate; miRTarBase -0.57 2.0E-5 21468550; 25994220; 25381586; 26555418; 23359184; 22964582; 21376256 BCL-2 up-regulation could be achieved by miR-21 overexpression which prevented T24 cells from apoptosis induced by doxorubicin; Furthermore the miR-21 induced BCL-2 up-regulation could be cancelled by the PI3K inhibitor LY294002;Meanwhile miR-21 loss reduced STAT3 and Bcl-2 activation causing an increase in the apoptosis of tumour cells in CAC mice;Changes in the sensitivity of osteosarcoma cells to CDDP were examined after transfection with miR-21 mimics or anti-miR-21 or bcl-2 siRNA in combination with CDDP;The expression of Bax Bcl-2 and miR-21 in parental and paclitaxel-resistant cells was detected by RT-PCR and Western blotting;Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR 21 regulation of BCL 2 expression; We also used Western blot to measure BCL-2 protein levels after down-regulation of miR-21 expression; Besides down-regulation of miR-21 expression can inhibit BCL-2 expression in PANC-1 CFPAC-1 and MIA Paca-2 cells; Over-expression of miR-21 expression can reverse down-regulation of BCL-2 expression and apoptosis induced by resveratrol; In this study we demonstrated that the effect of resveratrol on apoptosis is due to inhibiting miR-21 regulation of BCL-2 expression;Tumors harvested from these lungs have elevated levels of oncogenic miRNAs miR-21 and miR-155; are deficient for p53-regulated miRNAs; and have heightened expression of miR-34 target genes such as Met and Bcl-2;Bcl 2 upregulation induced by miR 21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa 2 pancreatic cancer cells; However the roles and mechanisms of miRNA miR-21 in regulation of Bcl-2 in pancreatic cancer remain to be elucidated; Then luciferase activity was observed after miR-21 mimics and pRL-TK plasmids containing wild-type and mutant 3'UTRs of Bcl-2 mRNA were co-transfected; Cells transfected with miR-21 inhibitor revealed an opposite trend. There was a significant increase in luciferase activity in the cells transfected with the wild-type pRL-TK plasmid in contrast to those transfected with the mutant one indicating that miR-21 promotes Bcl-2 expression by binding directly to the 3'UTR of Bcl-2 mRNA; Upregulation of Bcl-2 directly induced by miR-21 is associated with apoptosis chemoresistance and proliferation of MIA PaCa-2 pancreatic cancer cells
40 hsa-miR-29a-5p BCL2 0.59 0.02301 -1.09 0.00317 mirMAP -0.28 0.00622 20041405 Subsequent investigation characterized two antiapoptotic molecules Bcl-2 and Mcl-1 as direct targets of miR-29; Furthermore silencing of Bcl-2 and Mcl-1 phenocopied the proapoptotic effect of miR-29 whereas overexpression of these proteins attenuated the effect of miR-29
41 hsa-miR-335-3p BCL2 2.52 0 -1.09 0.00317 mirMAP -0.17 0.00598 NA
42 hsa-miR-429 BCL2 1.4 0.009 -1.09 0.00317 miRNAWalker2 validate; miRTarBase; PITA; mirMAP -0.2 3.0E-5 23999873; 26513239; 26511969 MiR 429 up regulation induces apoptosis and suppresses invasion by targeting Bcl 2 and SP 1 in esophageal carcinoma; Subsequent Western blotting and luciferase reporter assays showed that miR-429 can bind to putative binding sites within the Bcl-2 and SP1 mRNA 3' untranslated regions UTRs to reduce their expression; Up-regulation of miR-429 inhibits invasion and promotes apoptosis in EC cells by targeting Bcl-2 and SP1; Our findings suggest that Bcl-2 and SP1 may serve as major targets of miR-429;MiR 429 Induces Gastric Carcinoma Cell Apoptosis Through Bcl 2; Here we studied the levels of miR-429 and anti-apoptotic protein Bcl-2 in GC specimens; We performed bioinformatics analyses and used luciferase-reporter assay to analyze the relationship between miR-429 and Bcl-2 in GC cells; MiR-429 levels were significantly decreased and Bcl-2 levels were significantly increased in GC specimens compared to the paired adjacent non-tumor gastric tissue; Moreover the levels of miR-429 and Bcl-2 inversely correlated in GC specimens; Bioinformatics analyses showed that miR-429 targeted the 3'-UTR of Bcl-2 mRNA to inhibit its translation which was confirmed by luciferase-reporter assay;MiR 429 induces apoptosis of glioblastoma cell through Bcl 2; Here we analyzed the levels of miR-429 and anti-apoptotic protein Bcl-2 in GBM specimens; We combined bioinformatics analyses and luciferase reporter assay to determine the relationship between miR-429 and Bcl-2 in GBM cells; We found that miR-429 levels were significantly decreased and Bcl-2 levels were significantly increased in GBM specimens compared to the paired adjacent non-tumor brain tissue; Moreover the levels of miR-429 and Bcl-2 inversely correlated; MiR-429 targeted the 3'-UTR of Bcl-2 mRNA to inhibit its translation
43 hsa-miR-455-5p BCL2 1.2 7.0E-5 -1.09 0.00317 mirMAP -0.35 4.0E-5 NA
44 hsa-miR-577 BCL2 0.91 0.22561 -1.09 0.00317 PITA -0.1 0.00537 NA
45 hsa-miR-7-5p BCL2 1.64 0.01244 -1.09 0.00317 miRNAWalker2 validate; miRTarBase; mirMAP -0.14 0.00068 26464649; 25862909; 21750649 Western blotting was used to evaluate the effect of miR-7 on Bcl2 in A549 and H460 cells; Moreover subsequent experiments showed that BCL-2 was downregulated by miR-7 at both transcriptional and translational levels; This study further extends the biological role of miR-7 in NSCLC A549 and H460 cells and identifies BCL-2 as a novel target possibly involved in miR-7-mediated growth suppression and apoptosis induction of NSCLC cells;miR-7 overexpression correlated with diminished BCL2 expression but there was no relationship between miR-7 and EGFR expression neither in tumour samples nor in the cell lines; Of the two postulated miR-7 target genes we examined BCL2 but not EGFR seems to be a possible miR-7 target in OC;Bioinformatics predictions revealed a potential binding site of miR-7 on 3'UTR of BCL-2 and it was further confirmed by luciferase assay; Moreover subsequent experiments showed that BCL-2 was downregulated by miR-7 at both transcriptional and translational levels; These results suggest that miR-7 regulates the expression of BCL-2 through direct 3'UTR interactions
46 hsa-let-7b-5p BCL2L1 0.06 0.7814 0.21 0.39578 miRNATAP -0.31 0.00027 26915294; 20347499 As a result transcript levels of the tumor-suppressive miR-15 and let-7 families increased which targeted and decreased the expression of the crucial prosurvival genes BCL-2 and BCL-XL respectively;The let 7 family of microRNAs inhibits Bcl xL expression and potentiates sorafenib induced apoptosis in human hepatocellular carcinoma; The effect of let-7 on Bcl-xL expression was examined by Western blot and a reporter assay; Microarray analysis followed by in silico target prediction identified let-7 microRNAs as being downregulated in Huh7 hepatoma cells in comparison with primary human hepatocytes as well as possessing a putative target site in the bcl-xl mRNA
47 hsa-let-7c-5p BCL2L1 -0.5 0.20685 0.21 0.39578 miRNAWalker2 validate; miRTarBase -0.2 1.0E-5 20347499 Over-expression of let-7c or let-7g led to a clear decrease of Bcl-xL expression in Huh7 and HepG2 cell lines; Reporter assays revealed direct post-transcriptional regulation involving let-7c or let-7g and the 3'-untranslated region of bcl-xl mRNA
48 hsa-miR-149-5p BCL2L1 0.71 0.29685 0.21 0.39578 mirMAP -0.17 0 NA
49 hsa-miR-214-3p BCL2L1 1.01 0.00625 0.21 0.39578 mirMAP -0.13 0.00824 NA
50 hsa-miR-23b-3p BCL2L1 -0.29 0.18665 0.21 0.39578 miRNAWalker2 validate -0.39 0 NA
51 hsa-miR-192-3p BDNF 0.36 0.74117 0.74 0.18381 MirTarget; miRNATAP -0.11 0.00424 NA
52 hsa-miR-29b-2-5p BDNF -1.7 0 0.74 0.18381 mirMAP -0.38 0.00762 NA
53 hsa-miR-338-5p BDNF -1.2 0.01003 0.74 0.18381 miRNATAP -0.3 0.00033 NA
54 hsa-miR-193b-3p CASP9 0.28 0.45126 -0.31 0.11004 miRNAWalker2 validate -0.17 0 NA
55 hsa-miR-338-3p CCND1 -0.96 0.01915 0.62 0.1312 miRNAWalker2 validate; miRTarBase; miRanda -0.24 0.00086 NA
56 hsa-let-7a-3p CCND2 0.5 0.04111 -0.5 0.3 mirMAP -0.54 0.0001 20418948 MicroRNA let 7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2
57 hsa-let-7b-3p CCND2 0.22 0.29604 -0.5 0.3 mirMAP -0.46 0.00588 NA
58 hsa-miR-106b-5p CCND2 1.71 0 -0.5 0.3 miRNAWalker2 validate; miRTarBase; miRNATAP -0.42 9.0E-5 NA
59 hsa-miR-130b-5p CCND2 0.7 0.05101 -0.5 0.3 mirMAP -0.39 2.0E-5 NA
60 hsa-miR-141-3p CCND2 1.46 0.00116 -0.5 0.3 MirTarget; TargetScan -0.21 0.00436 NA
61 hsa-miR-15b-5p CCND2 1.62 0 -0.5 0.3 miRNATAP -0.44 0.00021 NA
62 hsa-miR-16-2-3p CCND2 1.8 0 -0.5 0.3 mirMAP -0.55 0 NA
63 hsa-miR-16-5p CCND2 1.01 1.0E-5 -0.5 0.3 miRNAWalker2 validate; miRNATAP -0.67 1.0E-5 NA
64 hsa-miR-181a-2-3p CCND2 0.9 0.00083 -0.5 0.3 mirMAP -0.38 0.00236 NA
65 hsa-miR-182-5p CCND2 0.89 0.03106 -0.5 0.3 miRNAWalker2 validate; miRTarBase; miRNATAP -0.32 9.0E-5 NA
66 hsa-miR-183-5p CCND2 1.66 0.00052 -0.5 0.3 miRNATAP -0.29 2.0E-5 NA
67 hsa-miR-19b-3p CCND2 0.76 0.00653 -0.5 0.3 miRNAWalker2 validate; MirTarget; miRNATAP -0.32 0.00853 NA
68 hsa-miR-21-3p CCND2 1.75 0 -0.5 0.3 mirMAP -0.33 0.0051 NA
69 hsa-miR-224-3p CCND2 1.52 0.0065 -0.5 0.3 mirMAP -0.27 4.0E-5 NA
70 hsa-miR-26b-5p CCND2 -0.3 0.16008 -0.5 0.3 mirMAP; miRNATAP -0.58 0.00034 NA
71 hsa-miR-301a-3p CCND2 1.45 1.0E-5 -0.5 0.3 miRNAWalker2 validate -0.38 0.0002 NA
72 hsa-miR-3065-3p CCND2 -1.04 0.02184 -0.5 0.3 MirTarget; miRNATAP -0.2 0.00685 NA
73 hsa-miR-3065-5p CCND2 -0.24 0.63312 -0.5 0.3 mirMAP -0.24 0.00057 NA
74 hsa-miR-424-5p CCND2 1.09 0.00042 -0.5 0.3 miRNATAP -0.39 0.0003 NA
75 hsa-miR-429 CCND2 1.4 0.009 -0.5 0.3 miRNATAP -0.19 0.002 NA
76 hsa-miR-450b-5p CCND2 0.46 0.13274 -0.5 0.3 MirTarget; PITA; miRNATAP -0.32 0.00413 NA
77 hsa-miR-590-3p CCND2 1.12 0.00016 -0.5 0.3 miRanda; mirMAP -0.33 0.00348 NA
78 hsa-miR-590-5p CCND2 1.04 0.00027 -0.5 0.3 mirMAP -0.41 0.00055 NA
79 hsa-miR-9-3p CCND2 0.33 0.54111 -0.5 0.3 MirTarget; mirMAP; miRNATAP -0.19 0.00361 NA
80 hsa-miR-93-5p CCND2 1.75 0 -0.5 0.3 miRNATAP -0.32 0.00244 NA
81 hsa-miR-96-5p CCND2 1.14 0.00943 -0.5 0.3 TargetScan; miRNATAP -0.33 3.0E-5 NA
82 hsa-miR-96-5p CCND3 1.14 0.00943 0.04 0.88352 TargetScan -0.12 0.00328 NA
83 hsa-miR-125b-5p CCNE1 -0.51 0.13327 2.19 0 miRNAWalker2 validate -0.26 0.00155 NA
84 hsa-miR-195-5p CCNE1 -0.91 0.00151 2.19 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.43 1.0E-5 24402230 Furthermore through qPCR and western blot assays we showed that overexpression of miR-195-5p reduced CCNE1 mRNA and protein levels respectively
85 hsa-miR-497-5p CCNE1 -0.8 0.0036 2.19 0 MirTarget; miRNATAP -0.43 2.0E-5 24112607; 25909221; 24909281 Western blot assays confirmed that overexpression of miR-497 reduced cyclin E1 protein levels; Inhibited cellular growth suppressed cellular migration and invasion and G1 cell cycle arrest were observed upon overexpression of miR-497 in cells possibly by targeting cyclin E1;The effect of simultaneous overexpression of miR-497 and miR-34a on the inhibition of cell proliferation colony formation and tumor growth and the downregulation of cyclin E1 was stronger than the effect of each miRNA alone; The synergistic actions of miR-497 and miR-34a partly correlated with cyclin E1 levels; These results indicate cyclin E1 is downregulated by both miR-497 and miR-34a which synergistically retard the growth of human lung cancer cells;miR 497 suppresses proliferation of human cervical carcinoma HeLa cells by targeting cyclin E1; Furthermore the target effect of miR-497 on the CCNE1 was identified by dual-luciferase reporter assay system qRT-PCR and Western blotting; Over-expressed miR-497 in HeLa cells could suppress cell proliferation by targeting CCNE1
86 hsa-miR-26a-5p CCNE2 -0.38 0.04425 1.36 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.44 0.0001 24116110; 21901171 The loss of miR 26a mediated post transcriptional regulation of cyclin E2 in pancreatic cancer cell proliferation and decreased patient survival; The in vitro and in vivo assays showed that overexpression of miR-26a resulted in cell cycle arrest inhibited cell proliferation and decreased tumor growth which was associated with cyclin E2 downregulation;We also show that enforced expression of miR-26a in AML cells is able to inhibit cell cycle progression by downregulating cyclin E2 expression
87 hsa-miR-30a-5p CCNE2 -1.72 0 1.36 0 miRNATAP -0.22 0.00034 NA
88 hsa-miR-145-5p CDK4 -1.75 2.0E-5 1.16 0 miRNAWalker2 validate; miRTarBase -0.13 0.00065 21092188 Furthermore we found that CDK4 was regulated by miR-145 in cell cycle control
89 hsa-miR-195-5p CDK4 -0.91 0.00151 1.16 0 miRNAWalker2 validate; miRTarBase -0.16 0.00344 NA
90 hsa-miR-101-3p CDK6 -0.45 0.02834 0.3 0.4008 mirMAP -0.39 0.00173 NA
91 hsa-miR-129-5p CDK6 -2.57 0 0.3 0.4008 miRNAWalker2 validate -0.13 0.00427 24055727 Interestingly we showed that cyclin dependent kinase 6 CDK6 a cell cycle-associated protein involved in G1-S transition was a target of miR-129
92 hsa-miR-30d-3p CDK6 -0.55 0.04337 0.3 0.4008 mirMAP -0.28 0.00298 NA
93 hsa-miR-30d-5p CDK6 -0.55 0.01401 0.3 0.4008 mirMAP -0.44 9.0E-5 NA
94 hsa-let-7d-5p CDKN1A 0.98 0 -0.53 0.09948 MirTarget -0.4 0.00048 NA
95 hsa-let-7g-5p CDKN1A 0.33 0.24114 -0.53 0.09948 MirTarget -0.31 0.00013 NA
96 hsa-let-7i-5p CDKN1A 0.8 3.0E-5 -0.53 0.09948 MirTarget -0.32 0.00701 NA
97 hsa-miR-101-3p CDKN1A -0.45 0.02834 -0.53 0.09948 MirTarget -0.45 6.0E-5 NA
98 hsa-miR-106b-5p CDKN1A 1.71 0 -0.53 0.09948 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.32 1.0E-5 NA
99 hsa-miR-146a-5p CDKN1A 1.82 2.0E-5 -0.53 0.09948 miRNAWalker2 validate -0.18 0.00045 NA
100 hsa-miR-17-5p CDKN1A 1.66 0 -0.53 0.09948 miRNAWalker2 validate; miRTarBase; MirTarget; TargetScan; miRNATAP -0.26 0.00022 26482648; 24989082 The low expressions of miR-17 and miR-92 families can maintain cisplatin resistance through the regulation of CDKN1A and RAD21;According to PicTar and Miranda algorithms which predicted CDKN1A p21 as a putative target of miR-17 a luciferase assay was performed and revealed that miR-17 directly targets the 3'-UTR of p21 mRNA
101 hsa-miR-20a-5p CDKN1A 1.45 0 -0.53 0.09948 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.31 4.0E-5 26012475 Using the poorly tumorigenic and TGF-β-sensitive FET cell line that expresses low miR-20a levels we first confirmed that miR-20a downmodulated CDKN1A expression both at mRNA and protein level through direct binding to its 3'-UTR; Moreover besides modulating CDKN1A miR-20a blocked TGF-β-induced transactivation of its promoter without affecting the post-receptor activation of Smad3/4 effectors directly; Finally miR-20a abrogated the TGF-β-mediated c-Myc repression a direct inhibitor of the CDKN1A promoter activation most likely by reducing the expression of specific MYC-regulating genes from the Smad/E2F-based core repressor complex
102 hsa-miR-30b-3p CDKN1A -0.27 0.40085 -0.53 0.09948 MirTarget -0.23 0.00125 NA
103 hsa-miR-335-5p CDKN1A 1.6 6.0E-5 -0.53 0.09948 miRNAWalker2 validate -0.32 0 NA
104 hsa-miR-345-5p CDKN1A 1.84 0 -0.53 0.09948 miRNAWalker2 validate; miRTarBase; MirTarget -0.24 0.00033 NA
105 hsa-miR-423-3p CDKN1A 0.82 0.00026 -0.53 0.09948 miRNAWalker2 validate; miRTarBase -0.32 0.00138 NA
106 hsa-miR-423-5p CDKN1A 0.83 0.00079 -0.53 0.09948 MirTarget -0.41 0 NA
107 hsa-miR-429 CDKN1A 1.4 0.009 -0.53 0.09948 miRNATAP -0.13 0.00128 NA
108 hsa-miR-93-5p CDKN1A 1.75 0 -0.53 0.09948 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.32 1.0E-5 25633810 MicroRNA 93 activates c Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A; We confirmed that miR-93 directly bound with the 3' untranslated regions of the tumor-suppressor genes PTEN and CDKN1A respectivelyand inhibited their expression; We concluded that miR-93 stimulated cell proliferation migration and invasion through the oncogenic c-Met/PI3K/Akt pathway and also inhibited apoptosis by directly inhibiting PTEN and CDKN1A expression in human HCC
109 hsa-miR-942-5p CDKN1A 1.91 0 -0.53 0.09948 miRNAWalker2 validate -0.18 0.00704 NA
110 hsa-miR-24-3p CDKN1B 1.09 0 0.16 0.36377 miRNAWalker2 validate; miRNATAP -0.15 0.00772 26847530; 26044523 The biological significance of miR-24 expression in prostate cancer cells was assessed by a series of in vitro bioassays and the effect on proposed targets p27 CDKN1B and p16 CDK2NA was investigated;With the bioinformatic method we further identified that p27Kip1 is a direct target of miR-24-3p and its protein level was negatively regulated by miR-24-3p
111 hsa-miR-199a-3p CHAD 0.85 0.00036 -3.17 0 MirTarget; miRNATAP -0.61 0.00062 NA
112 hsa-miR-199b-3p CHAD 0.86 0.00032 -3.17 0 MirTarget -0.62 0.00059 NA
113 hsa-miR-222-5p CHAD 1.88 0 -3.17 0 MirTarget -0.29 0.0083 NA
114 hsa-miR-27a-3p CHRM1 1.3 0 -2.28 0.00338 miRNATAP -0.97 3.0E-5 NA
115 hsa-miR-10b-3p CHRM2 0.77 0.00766 -3.76 0 mirMAP -0.6 0.00138 NA
116 hsa-miR-126-5p CHRM2 0.42 0.07532 -3.76 0 mirMAP -0.75 0.00146 NA
117 hsa-miR-142-5p CHRM2 1.56 1.0E-5 -3.76 0 mirMAP -0.68 1.0E-5 NA
118 hsa-miR-16-1-3p CHRM2 1.43 0 -3.76 0 mirMAP -0.89 1.0E-5 NA
119 hsa-miR-17-5p CHRM2 1.66 0 -3.76 0 TargetScan -0.97 0 NA
120 hsa-miR-186-5p CHRM2 0.15 0.43471 -3.76 0 mirMAP -0.87 0.00291 NA
121 hsa-miR-29b-1-5p CHRM2 0.61 0.11636 -3.76 0 mirMAP -0.4 0.00463 NA
122 hsa-miR-335-3p CHRM2 2.52 0 -3.76 0 mirMAP -0.63 0 NA
123 hsa-miR-335-5p CHRM2 1.6 6.0E-5 -3.76 0 miRNAWalker2 validate -0.63 0 NA
124 hsa-miR-429 CHRM2 1.4 0.009 -3.76 0 miRanda -0.41 4.0E-5 NA
125 hsa-miR-501-5p CHRM2 0.27 0.45478 -3.76 0 mirMAP -0.52 0.00057 NA
126 hsa-miR-577 CHRM2 0.91 0.22561 -3.76 0 mirMAP -0.3 4.0E-5 NA
127 hsa-miR-590-3p CHRM2 1.12 0.00016 -3.76 0 mirMAP -0.86 0 NA
128 hsa-miR-152-3p CHUK 0.44 0.1617 -0.11 0.43611 MirTarget -0.17 0 NA
129 hsa-miR-195-5p CHUK -0.91 0.00151 -0.11 0.43611 miRNAWalker2 validate; MirTarget -0.13 0.00012 NA
130 hsa-miR-23a-3p CHUK 1.11 0 -0.11 0.43611 MirTarget -0.17 0.00056 NA
131 hsa-miR-23b-3p CHUK -0.29 0.18665 -0.11 0.43611 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.19 6.0E-5 NA
132 hsa-miR-342-3p CHUK 0.32 0.26915 -0.11 0.43611 miRanda -0.19 0 NA
133 hsa-miR-497-5p CHUK -0.8 0.0036 -0.11 0.43611 MirTarget -0.11 0.00273 NA
134 hsa-miR-107 COL1A1 0.9 5.0E-5 2.45 1.0E-5 PITA; miRanda -0.53 0.00258 NA
135 hsa-miR-126-5p COL1A1 0.42 0.07532 2.45 1.0E-5 miRNATAP -0.75 1.0E-5 NA
136 hsa-miR-150-5p COL1A1 0.15 0.75372 2.45 1.0E-5 miRNATAP -0.48 0 NA
137 hsa-miR-29a-3p COL1A1 -0.11 0.61501 2.45 1.0E-5 miRNATAP -0.7 7.0E-5 NA
138 hsa-miR-29b-3p COL1A1 -0.23 0.36746 2.45 1.0E-5 miRNAWalker2 validate; miRTarBase; miRNATAP -0.58 0.00018 NA
139 hsa-miR-29c-3p COL1A1 -1.62 0 2.45 1.0E-5 miRNAWalker2 validate; miRTarBase; miRNATAP -0.67 0 NA
140 hsa-miR-30a-3p COL1A1 -1.73 0 2.45 1.0E-5 mirMAP -0.44 0.0001 NA
141 hsa-miR-30b-3p COL1A1 -0.27 0.40085 2.45 1.0E-5 miRNATAP -0.6 0 NA
142 hsa-miR-30d-3p COL1A1 -0.55 0.04337 2.45 1.0E-5 mirMAP -0.73 0 NA
143 hsa-miR-30e-3p COL1A1 -0.91 1.0E-5 2.45 1.0E-5 mirMAP -0.87 0 NA
144 hsa-miR-330-3p COL1A1 0.8 0.00747 2.45 1.0E-5 mirMAP -0.37 0.00505 NA
145 hsa-miR-338-3p COL1A1 -0.96 0.01915 2.45 1.0E-5 miRanda; miRNATAP -0.48 0 NA
146 hsa-miR-361-3p COL1A1 -0.13 0.56605 2.45 1.0E-5 PITA -0.72 6.0E-5 NA
147 hsa-miR-532-3p COL1A1 0.55 0.09755 2.45 1.0E-5 PITA; miRNATAP -0.4 0.00062 NA
148 hsa-miR-577 COL1A1 0.91 0.22561 2.45 1.0E-5 MirTarget; PITA; miRNATAP -0.16 0.00265 NA
149 hsa-miR-625-5p COL1A1 0.54 0.2038 2.45 1.0E-5 MirTarget -0.31 0.00105 NA
150 hsa-miR-26a-5p COL1A2 -0.38 0.04425 1.3 0.00793 MirTarget; miRNATAP -0.59 0.0016 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF PHOSPHORUS METABOLIC PROCESS 110 1618 1.093e-61 5.085e-58
2 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 69 498 5.144e-57 1.197e-53
3 REGULATION OF KINASE ACTIVITY 79 776 2.577e-55 3.997e-52
4 REGULATION OF PROTEIN MODIFICATION PROCESS 104 1710 5.947e-53 6.918e-50
5 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 107 1848 1.12e-52 1.043e-49
6 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 73 689 5.217e-52 4.046e-49
7 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 84 1036 4.063e-51 2.363e-48
8 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 84 1036 4.063e-51 2.363e-48
9 POSITIVE REGULATION OF RESPONSE TO STIMULUS 107 1929 7.712e-51 3.987e-48
10 POSITIVE REGULATION OF CELL PROLIFERATION 75 814 4.211e-49 1.959e-46
11 POSITIVE REGULATION OF MOLECULAR FUNCTION 102 1791 4.759e-49 2.013e-46
12 REGULATION OF TRANSFERASE ACTIVITY 79 946 1.017e-48 3.942e-46
13 PROTEIN PHOSPHORYLATION 78 944 1.07e-47 3.829e-45
14 POSITIVE REGULATION OF KINASE ACTIVITY 61 482 1.216e-47 4.042e-45
15 INTRACELLULAR SIGNAL TRANSDUCTION 95 1572 2.489e-47 7.721e-45
16 REGULATION OF CELL PROLIFERATION 93 1496 3.172e-47 9.224e-45
17 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 92 1492 2.447e-46 6.698e-44
18 POSITIVE REGULATION OF CATALYTIC ACTIVITY 92 1518 1.058e-45 2.735e-43
19 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 81 1135 7.599e-45 1.861e-42
20 POSITIVE REGULATION OF CELL COMMUNICATION 91 1532 2.125e-44 4.495e-42
21 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 94 1656 2.086e-44 4.495e-42
22 LOCOMOTION 80 1114 1.962e-44 4.495e-42
23 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 62 616 2.351e-42 4.756e-40
24 PHOSPHORYLATION 81 1228 2.875e-42 5.574e-40
25 RESPONSE TO ENDOGENOUS STIMULUS 86 1450 1.461e-41 2.72e-39
26 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 70 876 1.958e-41 3.505e-39
27 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 90 1672 2.414e-40 4.16e-38
28 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 36 138 8.369e-40 1.391e-37
29 REGULATION OF CELLULAR COMPONENT MOVEMENT 65 771 1.051e-39 1.687e-37
30 REGULATION OF MAPK CASCADE 61 660 1.884e-39 2.922e-37
31 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 79 1275 3.897e-39 5.849e-37
32 POSITIVE REGULATION OF LOCOMOTION 51 420 1.153e-38 1.676e-36
33 CELL MOTILITY 66 835 1.321e-38 1.807e-36
34 LOCALIZATION OF CELL 66 835 1.321e-38 1.807e-36
35 POSITIVE REGULATION OF MAPK CASCADE 53 470 1.559e-38 2.072e-36
36 RESPONSE TO EXTERNAL STIMULUS 91 1821 3.069e-38 3.967e-36
37 RESPONSE TO OXYGEN CONTAINING COMPOUND 80 1381 1.454e-37 1.828e-35
38 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 52 470 2.31e-37 2.829e-35
39 REGULATION OF CELL DEATH 81 1472 1.829e-36 2.128e-34
40 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 69 1008 1.819e-36 2.128e-34
41 NEGATIVE REGULATION OF CELL DEATH 65 872 1.972e-36 2.238e-34
42 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 78 1395 1.935e-35 2.144e-33
43 EXTRACELLULAR STRUCTURE ORGANIZATION 43 304 2.221e-35 2.404e-33
44 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 69 1142 4.695e-33 4.965e-31
45 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 88 1977 6.459e-33 6.679e-31
46 RESPONSE TO HORMONE 62 893 7.031e-33 7.112e-31
47 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 40 289 1.59e-32 1.574e-30
48 BIOLOGICAL ADHESION 65 1032 4.659e-32 4.516e-30
49 TISSUE DEVELOPMENT 77 1518 4.767e-32 4.527e-30
50 REGULATION OF MAP KINASE ACTIVITY 40 319 8.37e-31 7.789e-29
51 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 57 799 1.018e-30 9.288e-29
52 PEPTIDYL TYROSINE MODIFICATION 33 186 1.512e-30 1.353e-28
53 RESPONSE TO GROWTH FACTOR 46 475 2.173e-30 1.907e-28
54 REGULATION OF CELL DIFFERENTIATION 73 1492 3.241e-29 2.793e-27
55 INOSITOL LIPID MEDIATED SIGNALING 28 124 3.813e-29 3.226e-27
56 RESPONSE TO NITROGEN COMPOUND 57 859 4.45e-29 3.698e-27
57 REGULATION OF HYDROLASE ACTIVITY 69 1327 4.685e-29 3.824e-27
58 REGULATION OF CELL ADHESION 50 629 5.203e-29 4.174e-27
59 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 42 404 5.561e-29 4.386e-27
60 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 33 213 1.553e-28 1.205e-26
61 ACTIVATION OF PROTEIN KINASE ACTIVITY 36 279 3.41e-28 2.601e-26
62 CELLULAR RESPONSE TO NITROGEN COMPOUND 44 505 3.921e-27 2.942e-25
63 TAXIS 42 464 1.477e-26 1.091e-24
64 VASCULATURE DEVELOPMENT 42 469 2.265e-26 1.621e-24
65 POSITIVE REGULATION OF MAP KINASE ACTIVITY 31 207 2.245e-26 1.621e-24
66 CELL SUBSTRATE ADHESION 28 164 1.557e-25 1.097e-23
67 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 57 1021 2.98e-25 2.069e-23
68 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 27 162 2.329e-24 1.594e-22
69 ORGAN MORPHOGENESIS 51 841 3.933e-24 2.652e-22
70 CELL DEVELOPMENT 65 1426 4.717e-24 3.135e-22
71 ANGIOGENESIS 33 293 5.853e-24 3.836e-22
72 CARDIOVASCULAR SYSTEM DEVELOPMENT 49 788 1.21e-23 7.716e-22
73 CIRCULATORY SYSTEM DEVELOPMENT 49 788 1.21e-23 7.716e-22
74 RESPONSE TO PEPTIDE 37 404 1.336e-23 8.403e-22
75 CELLULAR RESPONSE TO HORMONE STIMULUS 42 552 1.367e-23 8.479e-22
76 BLOOD VESSEL MORPHOGENESIS 35 364 4.705e-23 2.881e-21
77 REGULATION OF IMMUNE SYSTEM PROCESS 63 1403 6.426e-23 3.883e-21
78 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 52 957 1.965e-22 1.172e-20
79 PEPTIDYL AMINO ACID MODIFICATION 49 841 2.051e-22 1.208e-20
80 CELL DEATH 53 1001 2.336e-22 1.359e-20
81 IMMUNE SYSTEM PROCESS 74 1984 2.44e-22 1.402e-20
82 LEUKOCYTE MIGRATION 30 259 3.357e-22 1.905e-20
83 POSITIVE REGULATION OF CELL DIFFERENTIATION 48 823 5.709e-22 3.201e-20
84 RESPONSE TO ABIOTIC STIMULUS 53 1024 6.609e-22 3.661e-20
85 POSITIVE REGULATION OF HYDROLASE ACTIVITY 50 905 7.226e-22 3.956e-20
86 POSITIVE REGULATION OF GENE EXPRESSION 68 1733 1.429e-21 7.734e-20
87 LIPID PHOSPHORYLATION 21 99 1.759e-21 9.409e-20
88 RESPONSE TO LIPID 49 888 2.118e-21 1.12e-19
89 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 55 1152 4.132e-21 2.16e-19
90 CELL MATRIX ADHESION 22 119 4.643e-21 2.401e-19
91 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 48 867 5.1e-21 2.608e-19
92 NEUROGENESIS 60 1402 1.006e-20 5.089e-19
93 POSITIVE REGULATION OF CELL ADHESION 33 376 1.575e-20 7.882e-19
94 CELLULAR RESPONSE TO PEPTIDE 29 274 2.22e-20 1.099e-18
95 REGULATION OF LIPID KINASE ACTIVITY 16 48 3.773e-20 1.848e-18
96 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 16 49 5.55e-20 2.69e-18
97 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 67 1805 6.307e-20 3.025e-18
98 REGULATION OF EPITHELIAL CELL PROLIFERATION 29 285 6.675e-20 3.169e-18
99 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 17 62 1.106e-19 5.196e-18
100 RESPONSE TO WOUNDING 38 563 1.446e-19 6.728e-18
101 REGULATION OF VASCULATURE DEVELOPMENT 26 233 6.071e-19 2.797e-17
102 INTEGRIN MEDIATED SIGNALING PATHWAY 18 82 7.345e-19 3.351e-17
103 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 24 193 1.14e-18 5.149e-17
104 CELL PROLIFERATION 40 672 1.241e-18 5.552e-17
105 REGULATION OF CELL SUBSTRATE ADHESION 23 173 1.344e-18 5.954e-17
106 CELL ACTIVATION 37 568 1.496e-18 6.569e-17
107 REGULATION OF RESPONSE TO STRESS 58 1468 2.323e-18 1.01e-16
108 POSITIVE REGULATION OF CHEMOTAXIS 20 120 2.626e-18 1.131e-16
109 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 35 513 3.29e-18 1.404e-16
110 REGULATION OF CHEMOTAXIS 23 180 3.333e-18 1.41e-16
111 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 14 40 3.966e-18 1.662e-16
112 REGULATION OF NEURON DEATH 26 252 4.368e-18 1.815e-16
113 CELLULAR COMPONENT MORPHOGENESIS 45 900 5.452e-18 2.245e-16
114 NEURON PROJECTION DEVELOPMENT 35 545 2.193e-17 8.949e-16
115 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 27 296 2.28e-17 9.226e-16
116 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 21 154 2.632e-17 1.056e-15
117 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 54 1360 3.78e-17 1.503e-15
118 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 44 926 8.981e-17 3.531e-15
119 NEURON PROJECTION MORPHOGENESIS 30 402 9.031e-17 3.531e-15
120 LIPID MODIFICATION 23 210 1.082e-16 4.194e-15
121 WOUND HEALING 32 470 1.111e-16 4.274e-15
122 REGULATION OF EPITHELIAL CELL MIGRATION 21 166 1.265e-16 4.825e-15
123 REGULATION OF ERK1 AND ERK2 CASCADE 24 238 1.528e-16 5.779e-15
124 PROTEIN AUTOPHOSPHORYLATION 22 192 1.964e-16 7.369e-15
125 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 21 172 2.643e-16 9.837e-15
126 POSITIVE REGULATION OF CELL DIVISION 19 132 3.25e-16 1.2e-14
127 REGULATION OF ENDOTHELIAL CELL MIGRATION 18 114 3.705e-16 1.358e-14
128 RESPONSE TO CYTOKINE 38 714 4.047e-16 1.471e-14
129 REGULATION OF TRANSPORT 61 1804 4.176e-16 1.506e-14
130 RESPONSE TO STEROID HORMONE 32 497 5.494e-16 1.951e-14
131 POSITIVE REGULATION OF CELL DEATH 35 605 5.483e-16 1.951e-14
132 ACTIVATION OF MAPK ACTIVITY 19 137 6.616e-16 2.332e-14
133 NEURON DEVELOPMENT 37 687 7.138e-16 2.479e-14
134 POSITIVE REGULATION OF TRANSPORT 43 936 7.135e-16 2.479e-14
135 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 18 120 9.492e-16 3.272e-14
136 REGULATION OF IMMUNE RESPONSE 41 858 9.835e-16 3.365e-14
137 CELL PROJECTION ORGANIZATION 42 902 1.027e-15 3.488e-14
138 REGULATION OF DEVELOPMENTAL GROWTH 25 289 1.299e-15 4.379e-14
139 PLATELET ACTIVATION 19 142 1.308e-15 4.379e-14
140 RESPONSE TO ACID CHEMICAL 26 319 1.428e-15 4.745e-14
141 TUBE DEVELOPMENT 33 552 1.592e-15 5.255e-14
142 REGULATION OF CELL DEVELOPMENT 40 836 2.228e-15 7.299e-14
143 REGULATION OF GTPASE ACTIVITY 36 673 2.28e-15 7.418e-14
144 REGULATION OF CELL MATRIX ADHESION 16 90 2.404e-15 7.767e-14
145 REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 14 61 3.146e-15 1.01e-13
146 SINGLE ORGANISM CELL ADHESION 30 459 3.269e-15 1.042e-13
147 EMBRYO DEVELOPMENT 41 894 3.989e-15 1.263e-13
148 RESPONSE TO AMINO ACID 17 112 4.981e-15 1.566e-13
149 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 12 39 6.265e-15 1.956e-13
150 REGULATION OF BODY FLUID LEVELS 31 506 6.401e-15 1.986e-13
151 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 29 437 6.63e-15 2.043e-13
152 POSITIVE REGULATION OF CELL DEVELOPMENT 30 472 6.881e-15 2.106e-13
153 RESPONSE TO OXYGEN LEVELS 25 311 7.143e-15 2.172e-13
154 RESPONSE TO ORGANIC CYCLIC COMPOUND 41 917 9.404e-15 2.841e-13
155 NEURON DIFFERENTIATION 40 874 9.746e-15 2.926e-13
156 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 37 750 1.123e-14 3.35e-13
157 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 16 99 1.162e-14 3.442e-13
158 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 38 801 1.618e-14 4.764e-13
159 GLYCEROLIPID METABOLIC PROCESS 26 356 1.955e-14 5.722e-13
160 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 24 297 2.274e-14 6.614e-13
161 EPITHELIUM DEVELOPMENT 41 945 2.575e-14 7.443e-13
162 UROGENITAL SYSTEM DEVELOPMENT 24 299 2.639e-14 7.58e-13
163 REGULATION OF CELL CYCLE 41 949 2.964e-14 8.462e-13
164 REGULATION OF APOPTOTIC SIGNALING PATHWAY 26 363 3.094e-14 8.779e-13
165 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 24 303 3.541e-14 9.986e-13
166 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 14 74 5.627e-14 1.577e-12
167 CELLULAR RESPONSE TO STRESS 53 1565 5.766e-14 1.606e-12
168 REGULATION OF PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 13 60 7.042e-14 1.95e-12
169 GROWTH 27 410 7.334e-14 2.019e-12
170 REGULATION OF GROWTH 33 633 7.846e-14 2.148e-12
171 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 17 133 9.345e-14 2.543e-12
172 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 41 983 9.515e-14 2.574e-12
173 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 18 156 1.045e-13 2.81e-12
174 RESPONSE TO INSULIN 20 205 1.076e-13 2.877e-12
175 APOPTOTIC SIGNALING PATHWAY 23 289 1.126e-13 2.994e-12
176 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 25 360 2.003e-13 5.296e-12
177 GLAND DEVELOPMENT 26 395 2.222e-13 5.841e-12
178 RESPONSE TO ALCOHOL 25 362 2.269e-13 5.931e-12
179 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 25 368 3.28e-13 8.525e-12
180 RESPONSE TO ESTROGEN 20 218 3.448e-13 8.913e-12
181 REGULATION OF NEURON APOPTOTIC PROCESS 19 192 3.517e-13 9.042e-12
182 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 12 53 3.738e-13 9.558e-12
183 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 15 103 3.934e-13 1e-11
184 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 29 514 4.131e-13 1.045e-11
185 REGULATION OF CELLULAR LOCALIZATION 46 1277 4.482e-13 1.127e-11
186 REGULATION OF NEURON DIFFERENTIATION 30 554 4.513e-13 1.129e-11
187 HEMOSTASIS 23 311 5.274e-13 1.312e-11
188 REGULATION OF CELL PROJECTION ORGANIZATION 30 558 5.426e-13 1.343e-11
189 REGULATION OF LIPID METABOLIC PROCESS 22 282 5.932e-13 1.46e-11
190 REGULATION OF PROTEIN LOCALIZATION 39 950 6.9e-13 1.69e-11
191 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 17 153 9.655e-13 2.352e-11
192 POSITIVE REGULATION OF LIPID KINASE ACTIVITY 10 32 1.007e-12 2.441e-11
193 TISSUE MORPHOGENESIS 29 533 1.02e-12 2.46e-11
194 FORMATION OF PRIMARY GERM LAYER 15 110 1.059e-12 2.541e-11
195 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 20 232 1.108e-12 2.644e-11
196 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 23 323 1.161e-12 2.755e-11
197 POSITIVE REGULATION OF GROWTH 20 238 1.782e-12 4.209e-11
198 PHOSPHOLIPID METABOLIC PROCESS 24 364 1.905e-12 4.478e-11
199 GLYCEROLIPID BIOSYNTHETIC PROCESS 19 211 1.92e-12 4.489e-11
200 REGULATION OF CELLULAR PROTEIN LOCALIZATION 29 552 2.423e-12 5.637e-11
201 CELL PART MORPHOGENESIS 31 633 2.461e-12 5.697e-11
202 POSITIVE REGULATION OF NEURON DIFFERENTIATION 22 306 3.047e-12 7.02e-11
203 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 14 98 3.2e-12 7.334e-11
204 REGULATION OF NEURON PROJECTION DEVELOPMENT 25 408 3.223e-12 7.352e-11
205 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 14 99 3.691e-12 8.379e-11
206 NEGATIVE REGULATION OF ANOIKIS 8 17 3.915e-12 8.8e-11
207 REGULATION OF ENDOTHELIAL CELL CHEMOTAXIS 8 17 3.915e-12 8.8e-11
208 REGULATION OF PHOSPHOLIPASE ACTIVITY 12 64 4.143e-12 9.268e-11
209 CELLULAR RESPONSE TO CYTOKINE STIMULUS 30 606 4.392e-12 9.777e-11
210 REGULATION OF JAK STAT CASCADE 16 144 4.594e-12 1.013e-10
211 REGULATION OF STAT CASCADE 16 144 4.594e-12 1.013e-10
212 NEGATIVE REGULATION OF NEURON DEATH 17 171 5.953e-12 1.307e-10
213 POSITIVE REGULATION OF LIPASE ACTIVITY 12 66 6.093e-12 1.331e-10
214 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 12 67 7.351e-12 1.598e-10
215 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT PROTEIN 12 68 8.842e-12 1.905e-10
216 IMMUNE SYSTEM DEVELOPMENT 29 582 8.827e-12 1.905e-10
217 RESPONSE TO DRUG 25 431 1.064e-11 2.282e-10
218 NEURON PROJECTION GUIDANCE 18 205 1.148e-11 2.448e-10
219 NEGATIVE REGULATION OF CELL COMMUNICATION 42 1192 1.152e-11 2.448e-10
220 FC RECEPTOR SIGNALING PATHWAY 18 206 1.246e-11 2.636e-10
221 CELL CELL SIGNALING 33 767 1.487e-11 3.13e-10
222 POSITIVE REGULATION OF CELL CYCLE 22 332 1.523e-11 3.192e-10
223 CELL SUBSTRATE JUNCTION ASSEMBLY 10 41 1.607e-11 3.353e-10
224 RESPONSE TO KETONE 17 182 1.628e-11 3.381e-10
225 RESPONSE TO EXTRACELLULAR STIMULUS 25 441 1.746e-11 3.611e-10
226 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 23 370 1.876e-11 3.862e-10
227 REGULATION OF DEPHOSPHORYLATION 16 158 1.919e-11 3.935e-10
228 REGULATION OF CELL DIVISION 20 272 2.069e-11 4.222e-10
229 POSITIVE REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 10 42 2.089e-11 4.245e-10
230 POSITIVE REGULATION OF STAT CASCADE 12 73 2.128e-11 4.287e-10
231 POSITIVE REGULATION OF JAK STAT CASCADE 12 73 2.128e-11 4.287e-10
232 POSITIVE REGULATION OF IMMUNE RESPONSE 28 563 2.178e-11 4.368e-10
233 MULTICELLULAR ORGANISM METABOLIC PROCESS 13 93 2.58e-11 5.152e-10
234 CELL CHEMOTAXIS 16 162 2.812e-11 5.591e-10
235 RESPONSE TO FIBROBLAST GROWTH FACTOR 14 116 3.342e-11 6.617e-10
236 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 10 44 3.457e-11 6.815e-10
237 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 11 59 3.546e-11 6.962e-10
238 OSSIFICATION 19 251 4.065e-11 7.948e-10
239 REGULATION OF INTRACELLULAR TRANSPORT 29 621 4.202e-11 8.18e-10
240 HEAD DEVELOPMENT 31 709 4.412e-11 8.554e-10
241 MORPHOGENESIS OF A BRANCHING STRUCTURE 16 167 4.464e-11 8.618e-10
242 FC EPSILON RECEPTOR SIGNALING PATHWAY 15 142 4.538e-11 8.725e-10
243 REGULATION OF AXONOGENESIS 16 168 4.887e-11 9.357e-10
244 ACTIVATION OF IMMUNE RESPONSE 24 427 5.435e-11 1.036e-09
245 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 12 79 5.598e-11 1.063e-09
246 REGULATION OF PROTEIN KINASE B SIGNALING 14 121 5.957e-11 1.127e-09
247 REGULATION OF CELL SIZE 16 172 6.975e-11 1.314e-09
248 REGULATION OF CELL MORPHOGENESIS 27 552 7.44e-11 1.396e-09
249 PEPTIDYL SERINE MODIFICATION 15 148 8.231e-11 1.538e-09
250 CELLULAR RESPONSE TO ACID CHEMICAL 16 175 9.053e-11 1.685e-09
251 REGULATION OF LIPASE ACTIVITY 12 83 1.019e-10 1.889e-09
252 REGULATION OF ANOIKIS 8 24 1.109e-10 2.048e-09
253 PHOSPHOLIPID BIOSYNTHETIC PROCESS 18 235 1.114e-10 2.048e-09
254 HOMEOSTATIC PROCESS 43 1337 1.17e-10 2.143e-09
255 FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 12 84 1.178e-10 2.149e-09
256 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 15 152 1.206e-10 2.191e-09
257 REGULATION OF PHOSPHATASE ACTIVITY 14 128 1.28e-10 2.308e-09
258 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 14 128 1.28e-10 2.308e-09
259 REPRODUCTIVE SYSTEM DEVELOPMENT 23 408 1.324e-10 2.378e-09
260 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 21 337 1.415e-10 2.532e-09
261 GASTRULATION 15 155 1.593e-10 2.84e-09
262 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 8 25 1.616e-10 2.87e-09
263 CYTOKINE MEDIATED SIGNALING PATHWAY 24 452 1.743e-10 3.084e-09
264 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 17 213 1.968e-10 3.469e-09
265 POSITIVE REGULATION OF AXONOGENESIS 11 69 2.101e-10 3.675e-09
266 RESPONSE TO ACTIVITY 11 69 2.101e-10 3.675e-09
267 POSITIVE REGULATION OF CELL ACTIVATION 20 311 2.279e-10 3.971e-09
268 EMBRYONIC MORPHOGENESIS 26 539 2.32e-10 4.028e-09
269 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 10 53 2.494e-10 4.298e-09
270 CELLULAR RESPONSE TO AMINO ACID STIMULUS 10 53 2.494e-10 4.298e-09
271 RESPONSE TO LIGHT STIMULUS 19 280 2.649e-10 4.549e-09
272 REGULATION OF HEMOPOIESIS 20 314 2.7e-10 4.618e-09
273 REGULATION OF PHOSPHOLIPASE C ACTIVITY 9 39 2.938e-10 4.998e-09
274 REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 7 17 2.943e-10 4.998e-09
275 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 15 162 2.982e-10 5.045e-09
276 POSITIVE REGULATION OF CELL MATRIX ADHESION 9 40 3.755e-10 6.331e-09
277 NEPHRON DEVELOPMENT 13 115 3.935e-10 6.609e-09
278 CENTRAL NERVOUS SYSTEM DEVELOPMENT 33 872 4.199e-10 7.028e-09
279 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 23 437 5.087e-10 8.464e-09
280 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 27 602 5.093e-10 8.464e-09
281 MORPHOGENESIS OF AN EPITHELIUM 22 400 5.437e-10 9.003e-09
282 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 37 1087 6.169e-10 1.018e-08
283 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 16 200 6.608e-10 1.087e-08
284 REGULATION OF CELL ACTIVATION 24 484 6.927e-10 1.131e-08
285 POSITIVE REGULATION OF ENDOTHELIAL CELL CHEMOTAXIS 6 11 6.911e-10 1.131e-08
286 CELLULAR RESPONSE TO ABIOTIC STIMULUS 18 263 6.951e-10 1.131e-08
287 MEMORY 12 98 7.406e-10 1.189e-08
288 CELLULAR RESPONSE TO EXTERNAL STIMULUS 18 264 7.389e-10 1.189e-08
289 REGULATION OF LEUKOCYTE DIFFERENTIATION 17 232 7.41e-10 1.189e-08
290 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 12 98 7.406e-10 1.189e-08
291 RESPONSE TO ESTRADIOL 14 146 7.466e-10 1.19e-08
292 CELLULAR RESPONSE TO INSULIN STIMULUS 14 146 7.466e-10 1.19e-08
293 HOMEOSTASIS OF NUMBER OF CELLS 15 175 8.819e-10 1.401e-08
294 REGULATION OF GLUCOSE IMPORT 10 60 9.024e-10 1.423e-08
295 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 10 60 9.024e-10 1.423e-08
296 POSITIVE REGULATION OF MITOTIC CELL CYCLE 13 123 9.162e-10 1.44e-08
297 RESPONSE TO RADIATION 22 413 9.893e-10 1.55e-08
298 INFLAMMATORY RESPONSE 23 454 1.065e-09 1.662e-08
299 REGULATION OF DNA METABOLIC PROCESS 20 340 1.085e-09 1.686e-08
300 INSULIN RECEPTOR SIGNALING PATHWAY 11 80 1.087e-09 1.686e-08
301 CELLULAR RESPONSE TO GROWTH HORMONE STIMULUS 7 20 1.141e-09 1.764e-08
302 CELLULAR RESPONSE TO LIPID 23 457 1.208e-09 1.862e-08
303 REGULATION OF FIBROBLAST PROLIFERATION 11 81 1.246e-09 1.913e-08
304 REGULATION OF CELL CELL ADHESION 21 380 1.258e-09 1.926e-08
305 CELLULAR LIPID METABOLIC PROCESS 33 913 1.341e-09 2.046e-08
306 RESPONSE TO MECHANICAL STIMULUS 16 210 1.351e-09 2.054e-08
307 SINGLE ORGANISM BEHAVIOR 21 384 1.518e-09 2.301e-08
308 CELL JUNCTION ASSEMBLY 13 129 1.658e-09 2.505e-08
309 TISSUE MIGRATION 11 84 1.855e-09 2.793e-08
310 POSITIVE REGULATION OF DNA METABOLIC PROCESS 15 185 1.909e-09 2.856e-08
311 CELL JUNCTION ORGANIZATION 15 185 1.909e-09 2.856e-08
312 SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 8 33 1.925e-09 2.861e-08
313 EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 8 33 1.925e-09 2.861e-08
314 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 13 131 2.007e-09 2.974e-08
315 REGULATION OF CELLULAR RESPONSE TO STRESS 28 691 2.296e-09 3.392e-08
316 POSITIVE REGULATION OF DNA REPLICATION 11 86 2.397e-09 3.529e-08
317 COGNITION 17 251 2.467e-09 3.621e-08
318 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 19 321 2.605e-09 3.812e-08
319 NEGATIVE REGULATION OF CELL DIFFERENTIATION 26 609 3.072e-09 4.481e-08
320 REGULATION OF ADHERENS JUNCTION ORGANIZATION 9 50 3.131e-09 4.524e-08
321 STAT CASCADE 9 50 3.131e-09 4.524e-08
322 JAK STAT CASCADE 9 50 3.131e-09 4.524e-08
323 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 13 136 3.187e-09 4.577e-08
324 GLIAL CELL DIFFERENTIATION 13 136 3.187e-09 4.577e-08
325 REGULATION OF CELL JUNCTION ASSEMBLY 10 68 3.226e-09 4.618e-08
326 LEUKOCYTE DIFFERENTIATION 18 292 3.676e-09 5.247e-08
327 REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 9 51 3.766e-09 5.359e-08
328 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 15 195 3.939e-09 5.588e-08
329 POSITIVE CHEMOTAXIS 8 36 4.079e-09 5.768e-08
330 TELENCEPHALON DEVELOPMENT 16 228 4.444e-09 6.266e-08
331 RESPIRATORY SYSTEM DEVELOPMENT 15 197 4.53e-09 6.368e-08
332 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 16 229 4.732e-09 6.632e-08
333 DEVELOPMENTAL GROWTH 19 333 4.758e-09 6.649e-08
334 REGULATION OF POSITIVE CHEMOTAXIS 7 24 4.909e-09 6.818e-08
335 REGULATION OF PROTEIN PHOSPHATASE TYPE 2A ACTIVITY 7 24 4.909e-09 6.818e-08
336 RHYTHMIC PROCESS 18 298 5.061e-09 7.009e-08
337 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 8 37 5.155e-09 7.118e-08
338 MAMMARY GLAND EPITHELIUM DEVELOPMENT 9 53 5.384e-09 7.411e-08
339 GLUCOSE HOMEOSTASIS 14 170 5.485e-09 7.507e-08
340 CARBOHYDRATE HOMEOSTASIS 14 170 5.485e-09 7.507e-08
341 REGULATION OF RESPONSE TO WOUNDING 21 413 5.525e-09 7.539e-08
342 MAMMARY GLAND DEVELOPMENT 12 117 5.829e-09 7.93e-08
343 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 14 171 5.918e-09 8.028e-08
344 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 12 118 6.427e-09 8.668e-08
345 MESODERM DEVELOPMENT 12 118 6.427e-09 8.668e-08
346 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 8 38 6.469e-09 8.7e-08
347 CHEMICAL HOMEOSTASIS 31 874 6.995e-09 9.379e-08
348 T CELL RECEPTOR SIGNALING PATHWAY 13 146 7.596e-09 1.016e-07
349 GLIOGENESIS 14 175 7.974e-09 1.063e-07
350 PEPTIDYL TYROSINE AUTOPHOSPHORYLATION 8 39 8.063e-09 1.072e-07
351 MESODERMAL CELL DIFFERENTIATION 7 26 9.158e-09 1.214e-07
352 RESPONSE TO BIOTIC STIMULUS 31 886 9.606e-09 1.27e-07
353 RESPONSE TO VITAMIN 11 98 9.792e-09 1.29e-07
354 RESPONSE TO TOXIC SUBSTANCE 16 241 9.815e-09 1.29e-07
355 MYELOID LEUKOCYTE MIGRATION 11 99 1.091e-08 1.43e-07
356 POSITIVE REGULATION OF CELL CELL ADHESION 16 243 1.104e-08 1.443e-07
357 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 6 16 1.145e-08 1.492e-07
358 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 11 100 1.214e-08 1.578e-07
359 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 7 27 1.225e-08 1.588e-07
360 NEGATIVE REGULATION OF CELL CYCLE 21 433 1.262e-08 1.632e-07
361 CELL CELL ADHESION 25 608 1.333e-08 1.718e-07
362 PALLIUM DEVELOPMENT 13 153 1.34e-08 1.723e-07
363 ERBB SIGNALING PATHWAY 10 79 1.44e-08 1.846e-07
364 FOREBRAIN DEVELOPMENT 19 357 1.471e-08 1.88e-07
365 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 14 184 1.516e-08 1.933e-07
366 REGULATION OF ORGANELLE ORGANIZATION 36 1178 1.833e-08 2.331e-07
367 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 10 81 1.842e-08 2.336e-07
368 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 12 131 2.111e-08 2.669e-07
369 REPRODUCTION 38 1297 2.132e-08 2.689e-07
370 REGULATION OF HOMEOSTATIC PROCESS 21 447 2.189e-08 2.752e-07
371 RESPONSE TO NUTRIENT 14 191 2.438e-08 3.058e-07
372 REGENERATION 13 161 2.474e-08 3.086e-07
373 REGULATION OF DNA REPLICATION 13 161 2.474e-08 3.086e-07
374 SPROUTING ANGIOGENESIS 8 45 2.671e-08 3.323e-07
375 LIPID BIOSYNTHETIC PROCESS 23 539 2.687e-08 3.333e-07
376 RESPONSE TO GROWTH HORMONE 7 30 2.731e-08 3.371e-07
377 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 7 30 2.731e-08 3.371e-07
378 POSITIVE REGULATION OF HEMOPOIESIS 13 163 2.867e-08 3.521e-07
379 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 23 541 2.875e-08 3.521e-07
380 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 23 541 2.875e-08 3.521e-07
381 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 12 135 2.962e-08 3.607e-07
382 CONNECTIVE TISSUE DEVELOPMENT 14 194 2.969e-08 3.607e-07
383 CELL GROWTH 12 135 2.962e-08 3.607e-07
384 POSITIVE REGULATION OF LEUKOCYTE MIGRATION 11 109 3.02e-08 3.66e-07
385 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 15 228 3.252e-08 3.93e-07
386 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 10 86 3.312e-08 3.993e-07
387 OVULATION CYCLE PROCESS 10 88 4.143e-08 4.955e-07
388 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 10 88 4.143e-08 4.955e-07
389 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 10 88 4.143e-08 4.955e-07
390 LYMPHOCYTE ACTIVATION 18 342 4.243e-08 5.062e-07
391 POSITIVE REGULATION OF NEURON DEATH 9 67 4.552e-08 5.403e-07
392 RESPONSE TO GLUCAGON 8 48 4.546e-08 5.403e-07
393 REGULATION OF MITOTIC CELL CYCLE 21 468 4.799e-08 5.682e-07
394 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 32 1004 4.832e-08 5.706e-07
395 REGULATION OF HOMOTYPIC CELL CELL ADHESION 17 307 4.907e-08 5.78e-07
396 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 9 68 5.197e-08 6.107e-07
397 GLOMERULUS DEVELOPMENT 8 49 5.382e-08 6.308e-07
398 REGULATION OF LEUKOCYTE PROLIFERATION 14 206 6.312e-08 7.379e-07
399 LEUKOCYTE CHEMOTAXIS 11 117 6.329e-08 7.381e-07
400 MITOCHONDRIAL MEMBRANE ORGANIZATION 10 92 6.372e-08 7.412e-07
401 REGULATION OF PEPTIDASE ACTIVITY 19 392 6.502e-08 7.544e-07
402 REGULATION OF MEMBRANE PERMEABILITY 9 70 6.73e-08 7.79e-07
403 REGULATION OF DEFENSE RESPONSE 27 759 6.802e-08 7.853e-07
404 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 7 34 6.955e-08 7.991e-07
405 PROTEIN KINASE B SIGNALING 7 34 6.955e-08 7.991e-07
406 RESPONSE TO CORTICOSTEROID 13 176 7.127e-08 8.168e-07
407 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 16 278 7.251e-08 8.289e-07
408 CELL CYCLE PROCESS 33 1081 8.016e-08 9.142e-07
409 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 23 573 8.162e-08 9.286e-07
410 REGULATION OF CELLULAR COMPONENT BIOGENESIS 27 767 8.409e-08 9.543e-07
411 SKIN DEVELOPMENT 14 211 8.51e-08 9.634e-07
412 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 11 121 8.966e-08 1.013e-06
413 CELL CYCLE 37 1316 9.649e-08 1.087e-06
414 TUBE MORPHOGENESIS 17 323 1.021e-07 1.148e-06
415 GLAND MORPHOGENESIS 10 97 1.06e-07 1.186e-06
416 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 7 36 1.059e-07 1.186e-06
417 CELL ADHESION MEDIATED BY INTEGRIN 5 12 1.094e-07 1.218e-06
418 POSITIVE REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 5 12 1.094e-07 1.218e-06
419 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 18 365 1.131e-07 1.256e-06
420 SENSORY ORGAN DEVELOPMENT 21 493 1.154e-07 1.278e-06
421 LIPID METABOLIC PROCESS 34 1158 1.255e-07 1.387e-06
422 CELL CYCLE ARREST 12 154 1.279e-07 1.407e-06
423 AMEBOIDAL TYPE CELL MIGRATION 12 154 1.279e-07 1.407e-06
424 SECRETION 23 588 1.297e-07 1.423e-06
425 POSITIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 6 23 1.354e-07 1.482e-06
426 RESPONSE TO UV 11 126 1.36e-07 1.486e-06
427 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 8 55 1.374e-07 1.497e-06
428 SKELETAL SYSTEM DEVELOPMENT 20 455 1.419e-07 1.532e-06
429 LEUKOCYTE CELL CELL ADHESION 15 255 1.416e-07 1.532e-06
430 REGULATION OF GLUCOSE TRANSPORT 10 100 1.418e-07 1.532e-06
431 LIMBIC SYSTEM DEVELOPMENT 10 100 1.418e-07 1.532e-06
432 LEUKOCYTE ACTIVATION 19 414 1.522e-07 1.64e-06
433 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 13 188 1.543e-07 1.658e-06
434 NEGATIVE REGULATION OF TRANSPORT 20 458 1.577e-07 1.691e-06
435 NEGATIVE REGULATION OF CELL PROLIFERATION 24 643 1.611e-07 1.724e-06
436 DEFENSE RESPONSE 35 1231 1.732e-07 1.848e-06
437 CELLULAR RESPONSE TO HEPATOCYTE GROWTH FACTOR STIMULUS 5 13 1.762e-07 1.871e-06
438 RESPONSE TO HEPATOCYTE GROWTH FACTOR 5 13 1.762e-07 1.871e-06
439 ENDOTHELIAL CELL MIGRATION 8 57 1.83e-07 1.94e-06
440 ERBB2 SIGNALING PATHWAY 7 39 1.899e-07 2.008e-06
441 HEART DEVELOPMENT 20 466 2.08e-07 2.195e-06
442 CEREBRAL CORTEX DEVELOPMENT 10 105 2.254e-07 2.373e-06
443 ENDODERMAL CELL DIFFERENTIATION 7 40 2.28e-07 2.395e-06
444 POSITIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 6 25 2.332e-07 2.444e-06
445 BEHAVIOR 21 516 2.46e-07 2.572e-06
446 NEGATIVE REGULATION OF MOLECULAR FUNCTION 32 1079 2.475e-07 2.582e-06
447 REGULATION OF ANATOMICAL STRUCTURE SIZE 20 472 2.551e-07 2.655e-06
448 PLATELET DEGRANULATION 10 107 2.694e-07 2.798e-06
449 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 5 14 2.716e-07 2.808e-06
450 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 5 14 2.716e-07 2.808e-06
451 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 14 232 2.737e-07 2.823e-06
452 REGULATION OF CELL GROWTH 18 391 3.131e-07 3.223e-06
453 OVARIAN FOLLICLE DEVELOPMENT 8 61 3.142e-07 3.227e-06
454 RESPONSE TO INORGANIC SUBSTANCE 20 479 3.221e-07 3.302e-06
455 POSITIVE REGULATION OF GLUCOSE TRANSPORT 7 42 3.239e-07 3.313e-06
456 REGULATION OF CYTOPLASMIC TRANSPORT 20 481 3.441e-07 3.511e-06
457 RESPONSE TO BACTERIUM 21 528 3.588e-07 3.654e-06
458 CELL CYCLE G1 S PHASE TRANSITION 10 111 3.805e-07 3.857e-06
459 G1 S TRANSITION OF MITOTIC CELL CYCLE 10 111 3.805e-07 3.857e-06
460 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 7 43 3.833e-07 3.878e-06
461 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 27 829 3.941e-07 3.978e-06
462 JAK STAT CASCADE INVOLVED IN GROWTH HORMONE SIGNALING PATHWAY 5 15 4.038e-07 4.067e-06
463 REGULATION OF INNATE IMMUNE RESPONSE 17 357 4.214e-07 4.235e-06
464 OVULATION CYCLE 10 113 4.497e-07 4.51e-06
465 TISSUE REMODELING 9 87 4.523e-07 4.526e-06
466 LYMPHOCYTE DIFFERENTIATION 13 209 5.224e-07 5.216e-06
467 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 9 89 5.501e-07 5.469e-06
468 EPITHELIAL CELL PROLIFERATION 9 89 5.501e-07 5.469e-06
469 POSITIVE REGULATION OF DEFENSE RESPONSE 17 364 5.523e-07 5.479e-06
470 FEMALE SEX DIFFERENTIATION 10 116 5.743e-07 5.686e-06
471 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT5 PROTEIN 5 16 5.821e-07 5.751e-06
472 POSITIVE REGULATION OF CELL CYCLE PROCESS 14 247 5.842e-07 5.753e-06
473 MESODERM MORPHOGENESIS 8 66 5.848e-07 5.753e-06
474 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 6 29 6.031e-07 5.908e-06
475 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 6 29 6.031e-07 5.908e-06
476 DIGESTIVE SYSTEM DEVELOPMENT 11 148 6.94e-07 6.784e-06
477 RESPONSE TO ANTIBIOTIC 7 47 7.21e-07 7.019e-06
478 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 7 47 7.21e-07 7.019e-06
479 REGULATION OF LEUKOCYTE MIGRATION 11 149 7.423e-07 7.21e-06
480 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 6 30 7.471e-07 7.242e-06
481 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 13 216 7.593e-07 7.345e-06
482 REGULATION OF SYSTEM PROCESS 20 507 7.849e-07 7.577e-06
483 POSITIVE REGULATION OF GLYCOGEN METABOLIC PROCESS 5 17 8.174e-07 7.874e-06
484 REGULATION OF PROTEIN IMPORT 12 183 8.257e-07 7.938e-06
485 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 7 48 8.364e-07 8.007e-06
486 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 7 48 8.364e-07 8.007e-06
487 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 13 218 8.426e-07 8.051e-06
488 CELL CYCLE PHASE TRANSITION 14 255 8.558e-07 8.159e-06
489 CELLULAR RESPONSE TO OXIDATIVE STRESS 12 184 8.749e-07 8.325e-06
490 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 19 465 8.896e-07 8.447e-06
491 INTRINSIC APOPTOTIC SIGNALING PATHWAY 11 152 9.052e-07 8.578e-06
492 HOMEOSTASIS OF NUMBER OF CELLS WITHIN A TISSUE 6 31 9.18e-07 8.682e-06
493 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 13 220 9.341e-07 8.816e-06
494 NEGATIVE REGULATION OF PHOSPHORYLATION 18 422 9.461e-07 8.911e-06
495 FC GAMMA RECEPTOR SIGNALING PATHWAY 9 95 9.61e-07 9.033e-06
496 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 7 49 9.668e-07 9.069e-06
497 REGULATION OF CELLULAR COMPONENT SIZE 16 337 9.688e-07 9.07e-06
498 T CELL DIFFERENTIATION 10 123 9.885e-07 9.236e-06
499 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 8 71 1.034e-06 9.621e-06
500 ENDODERM DEVELOPMENT 8 71 1.034e-06 9.621e-06
501 NEGATIVE REGULATION OF CELL ADHESION 13 223 1.088e-06 1.01e-05
502 ENDODERM FORMATION 7 50 1.114e-06 1.032e-05
503 REGULATION OF COLLATERAL SPROUTING 5 18 1.122e-06 1.038e-05
504 HIPPOCAMPUS DEVELOPMENT 8 73 1.282e-06 1.184e-05
505 RESPONSE TO REACTIVE OXYGEN SPECIES 12 191 1.299e-06 1.197e-05
506 MUSCLE STRUCTURE DEVELOPMENT 18 432 1.322e-06 1.215e-05
507 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 42 1784 1.428e-06 1.311e-05
508 SYSTEM PROCESS 42 1785 1.449e-06 1.327e-05
509 CELLULAR HOMEOSTASIS 23 676 1.465e-06 1.339e-05
510 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 10 129 1.531e-06 1.397e-05
511 REGULATION OF CATABOLIC PROCESS 24 731 1.594e-06 1.451e-05
512 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 7 53 1.672e-06 1.519e-05
513 SECRETION BY CELL 19 486 1.711e-06 1.546e-05
514 RESPONSE TO OXIDATIVE STRESS 16 352 1.711e-06 1.546e-05
515 IMMUNE EFFECTOR PROCESS 19 486 1.711e-06 1.546e-05
516 GLIAL CELL DEVELOPMENT 8 76 1.749e-06 1.577e-05
517 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 23 684 1.786e-06 1.608e-05
518 REGULATION OF GLYCOGEN METABOLIC PROCESS 6 35 1.951e-06 1.753e-05
519 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT5 PROTEIN 5 20 1.994e-06 1.788e-05
520 POSITIVE REGULATION OF PROTEIN IMPORT 9 104 2.065e-06 1.844e-05
521 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 9 104 2.065e-06 1.844e-05
522 ODONTOGENESIS 9 105 2.237e-06 1.994e-05
523 NEUROMUSCULAR JUNCTION DEVELOPMENT 6 36 2.321e-06 2.061e-05
524 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 6 36 2.321e-06 2.061e-05
525 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 18 450 2.353e-06 2.086e-05
526 INNATE IMMUNE RESPONSE ACTIVATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 9 106 2.422e-06 2.142e-05
527 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 7 56 2.447e-06 2.16e-05
528 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 17 406 2.46e-06 2.168e-05
529 REGULATION OF PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION 5 21 2.594e-06 2.269e-05
530 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 8 80 2.59e-06 2.269e-05
531 POSITIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 5 21 2.594e-06 2.269e-05
532 ACTIVATION OF INNATE IMMUNE RESPONSE 12 204 2.587e-06 2.269e-05
533 REGULATION OF T CELL DIFFERENTIATION 9 107 2.62e-06 2.287e-05
534 POSITIVE REGULATION OF LEUKOCYTE CHEMOTAXIS 8 81 2.847e-06 2.481e-05
535 TISSUE HOMEOSTASIS 11 171 2.879e-06 2.504e-05
536 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 9 109 3.057e-06 2.649e-05
537 RESPONSE TO HYDROGEN PEROXIDE 9 109 3.057e-06 2.649e-05
538 REGULATION OF SYNAPTIC PLASTICITY 10 140 3.219e-06 2.783e-05
539 CELLULAR RESPONSE TO GLUCAGON STIMULUS 6 38 3.23e-06 2.783e-05
540 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 6 38 3.23e-06 2.783e-05
541 POSITIVE REGULATION OF CYTOKINE PRODUCTION 16 370 3.253e-06 2.798e-05
542 ORGAN REGENERATION 8 83 3.427e-06 2.942e-05
543 REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 7 59 3.501e-06 3e-05
544 ASTROCYTE DIFFERENTIATION 6 39 3.783e-06 3.235e-05
545 REGULATION OF CYTOKINE PRODUCTION 20 563 3.877e-06 3.31e-05
546 CELLULAR RESPONSE TO OXYGEN LEVELS 10 143 3.895e-06 3.319e-05
547 MITOCHONDRIAL TRANSPORT 11 177 4.02e-06 3.42e-05
548 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 10 144 4.146e-06 3.514e-05
549 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 10 144 4.146e-06 3.514e-05
550 RESPONSE TO INCREASED OXYGEN LEVELS 5 23 4.214e-06 3.552e-05
551 RESPONSE TO HYPEROXIA 5 23 4.214e-06 3.552e-05
552 NEUROTROPHIN SIGNALING PATHWAY 5 23 4.214e-06 3.552e-05
553 POSITIVE REGULATION OF STEM CELL PROLIFERATION 7 61 4.395e-06 3.698e-05
554 SYNAPSE ORGANIZATION 10 145 4.412e-06 3.705e-05
555 CELLULAR CHEMICAL HOMEOSTASIS 20 570 4.661e-06 3.908e-05
556 CARTILAGE DEVELOPMENT 10 147 4.987e-06 4.173e-05
557 CELLULAR RESPONSE TO PROSTAGLANDIN STIMULUS 5 24 5.276e-06 4.399e-05
558 POSITIVE REGULATION OF CELL JUNCTION ASSEMBLY 5 24 5.276e-06 4.399e-05
559 POSITIVE REGULATION OF CELL GROWTH 10 148 5.298e-06 4.402e-05
560 RESPONSE TO TRANSITION METAL NANOPARTICLE 10 148 5.298e-06 4.402e-05
561 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 13 258 5.444e-06 4.515e-05
562 RESPONSE TO OSMOTIC STRESS 7 63 5.472e-06 4.531e-05
563 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 9 117 5.493e-06 4.54e-05
564 REGULATION OF MYELOID CELL DIFFERENTIATION 11 183 5.538e-06 4.569e-05
565 REGULATION OF CYTOKINE SECRETION 10 149 5.625e-06 4.633e-05
566 RESPONSE TO HEAT 8 89 5.802e-06 4.77e-05
567 PROTEIN COMPLEX BIOGENESIS 30 1132 5.993e-06 4.91e-05
568 PROTEIN COMPLEX ASSEMBLY 30 1132 5.993e-06 4.91e-05
569 REGULATION OF PROTEIN SECRETION 16 389 6.142e-06 5.022e-05
570 HEMIDESMOSOME ASSEMBLY 4 12 6.347e-06 5.163e-05
571 I KAPPAB PHOSPHORYLATION 4 12 6.347e-06 5.163e-05
572 ACTIVATION OF TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 4 12 6.347e-06 5.163e-05
573 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 7 65 6.76e-06 5.488e-05
574 REGULATED EXOCYTOSIS 12 224 6.77e-06 5.488e-05
575 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 6 43 6.816e-06 5.515e-05
576 AGING 13 264 6.981e-06 5.639e-05
577 REGULATION OF MULTICELLULAR ORGANISM GROWTH 7 66 7.493e-06 6.042e-05
578 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 10 154 7.541e-06 6.071e-05
579 SEX DIFFERENTIATION 13 266 7.572e-06 6.085e-05
580 MESENCHYME DEVELOPMENT 11 190 7.923e-06 6.345e-05
581 PHAGOCYTOSIS 11 190 7.923e-06 6.345e-05
582 REGULATION OF ION TRANSPORT 20 592 8.154e-06 6.519e-05
583 ENDOCRINE SYSTEM DEVELOPMENT 9 123 8.273e-06 6.602e-05
584 BONE DEVELOPMENT 10 156 8.452e-06 6.734e-05
585 EPITHELIAL CELL DIFFERENTIATION 18 495 8.773e-06 6.978e-05
586 EXOCRINE SYSTEM DEVELOPMENT 6 45 8.942e-06 7.088e-05
587 PROTEIN COMPLEX SUBUNIT ORGANIZATION 36 1527 8.938e-06 7.088e-05
588 POSITIVE REGULATION OF PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION 4 13 9.09e-06 7.193e-05
589 ORGAN GROWTH 7 68 9.157e-06 7.209e-05
590 REGULATION OF NEUROLOGICAL SYSTEM PROCESS 7 68 9.157e-06 7.209e-05
591 REGULATION OF TOR SIGNALING 7 68 9.157e-06 7.209e-05
592 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 8 95 9.443e-06 7.422e-05
593 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 27 9.757e-06 7.643e-05
594 HETEROTYPIC CELL CELL ADHESION 5 27 9.757e-06 7.643e-05
595 OSTEOBLAST DIFFERENTIATION 9 126 1.006e-05 7.87e-05
596 RESPONSE TO ENDOPLASMIC RETICULUM STRESS 12 233 1.009e-05 7.876e-05
597 REGULATION OF MUSCLE SYSTEM PROCESS 11 195 1.013e-05 7.897e-05
598 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 6 46 1.019e-05 7.928e-05
599 REGULATION OF LEUKOCYTE CHEMOTAXIS 8 96 1.021e-05 7.928e-05
600 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 8 97 1.102e-05 8.546e-05
601 REGULATION OF PROTEOLYSIS 22 711 1.131e-05 8.757e-05
602 MITOTIC CELL CYCLE 23 766 1.147e-05 8.854e-05
603 NEGATIVE REGULATION OF GROWTH 12 236 1.147e-05 8.854e-05
604 POSITIVE REGULATION OF ACTIVATED T CELL PROLIFERATION 5 28 1.177e-05 9.055e-05
605 REGULATION OF SPROUTING ANGIOGENESIS 5 28 1.177e-05 9.055e-05
606 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 8 98 1.189e-05 9.128e-05
607 INTERSPECIES INTERACTION BETWEEN ORGANISMS 21 662 1.248e-05 9.548e-05
608 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 21 662 1.248e-05 9.548e-05
609 POSITIVE REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 4 14 1.262e-05 9.608e-05
610 POSITIVE REGULATION OF NITRIC OXIDE SYNTHASE BIOSYNTHETIC PROCESS 4 14 1.262e-05 9.608e-05
611 POSITIVE REGULATION OF SPROUTING ANGIOGENESIS 4 14 1.262e-05 9.608e-05
612 SENSORY ORGAN MORPHOGENESIS 12 239 1.302e-05 9.901e-05
613 ORGANOPHOSPHATE METABOLIC PROCESS 25 885 1.326e-05 0.0001006
614 REGULATION OF VESICLE MEDIATED TRANSPORT 17 462 1.348e-05 0.0001022
615 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 13 282 1.413e-05 0.0001069
616 REGULATION OF METAL ION TRANSPORT 14 325 1.416e-05 0.0001069
617 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 20 616 1.453e-05 0.0001095
618 REGULATION OF ORGAN GROWTH 7 73 1.47e-05 0.0001099
619 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 9 132 1.466e-05 0.0001099
620 REGULATION OF LYMPHOCYTE DIFFERENTIATION 9 132 1.466e-05 0.0001099
621 REGULATION OF PLASMA MEMBRANE ORGANIZATION 7 73 1.47e-05 0.0001099
622 EYE DEVELOPMENT 14 326 1.465e-05 0.0001099
623 REGULATION OF ORGAN MORPHOGENESIS 12 242 1.475e-05 0.0001102
624 POSITIVE REGULATION OF CHEMOKINE PRODUCTION 6 49 1.481e-05 0.0001104
625 REGULATION OF EXTENT OF CELL GROWTH 8 101 1.485e-05 0.0001105
626 RESPONSE TO CARBOHYDRATE 10 168 1.618e-05 0.0001202
627 NEGATIVE REGULATION OF PEPTIDASE ACTIVITY 12 245 1.668e-05 0.0001238
628 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 4 15 1.706e-05 0.0001262
629 NEUROTROPHIN TRK RECEPTOR SIGNALING PATHWAY 4 15 1.706e-05 0.0001262
630 REGULATION OF MUSCLE ORGAN DEVELOPMENT 8 103 1.715e-05 0.0001266
631 POSITIVE REGULATION OF INNATE IMMUNE RESPONSE 12 246 1.737e-05 0.0001281
632 POSITIVE REGULATION OF CARBOHYDRATE METABOLIC PROCESS 7 75 1.758e-05 0.0001294
633 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 8 104 1.84e-05 0.0001353
634 RESPONSE TO ETHANOL 9 136 1.862e-05 0.0001367
635 POSITIVE REGULATION OF MITOTIC NUCLEAR DIVISION 6 51 1.872e-05 0.000137
636 CELLULAR RESPONSE TO FATTY ACID 6 51 1.872e-05 0.000137
637 REGULATION OF CALCIUM ION TRANSPORT 11 209 1.94e-05 0.0001417
638 RESPONSE TO ALKALOID 9 137 1.975e-05 0.0001438
639 CELLULAR RESPONSE TO RADIATION 9 137 1.975e-05 0.0001438
640 NEGATIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 5 31 1.982e-05 0.0001439
641 REGULATION OF PLATELET ACTIVATION 5 31 1.982e-05 0.0001439
642 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 15 381 2.014e-05 0.000146
643 NEGATIVE REGULATION OF KINASE ACTIVITY 12 250 2.038e-05 0.0001475
644 ACTIVATION OF MAPKK ACTIVITY 6 52 2.098e-05 0.0001516
645 REGULATION OF CELL SHAPE 9 139 2.217e-05 0.0001599
646 BRANCHING INVOLVED IN SALIVARY GLAND MORPHOGENESIS 4 16 2.255e-05 0.0001622
647 RESPONSE TO UV B 4 16 2.255e-05 0.0001622
648 EPIDERMIS DEVELOPMENT 12 253 2.293e-05 0.0001646
649 MULTI MULTICELLULAR ORGANISM PROCESS 11 213 2.313e-05 0.0001658
650 SALIVARY GLAND DEVELOPMENT 5 32 2.328e-05 0.0001667
651 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 6 53 2.344e-05 0.0001673
652 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 6 53 2.344e-05 0.0001673
653 REGULATION OF CELL CYCLE ARREST 8 108 2.423e-05 0.0001724
654 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 8 108 2.423e-05 0.0001724
655 IMMUNE RESPONSE 28 1100 2.617e-05 0.0001859
656 REGULATION OF OSSIFICATION 10 178 2.666e-05 0.0001891
657 POSITIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION 7 80 2.687e-05 0.00019
658 CELLULAR RESPONSE TO MECHANICAL STIMULUS 7 80 2.687e-05 0.00019
659 NEURON MIGRATION 8 110 2.768e-05 0.0001954
660 MODULATION OF SYNAPTIC TRANSMISSION 13 301 2.802e-05 0.0001975
661 REGULATION OF MITOCHONDRION ORGANIZATION 11 218 2.864e-05 0.0002016
662 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 6 55 2.907e-05 0.0002043
663 POSITIVE REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 4 17 2.924e-05 0.0002052
664 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 9 144 2.935e-05 0.0002056
665 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 8 111 2.956e-05 0.0002068
666 NEGATIVE REGULATION OF CELL DEVELOPMENT 13 303 3.001e-05 0.0002097
667 POSITIVE REGULATION OF CATABOLIC PROCESS 15 395 3.057e-05 0.0002133
668 ESTABLISHMENT OF PROTEIN LOCALIZATION 33 1423 3.098e-05 0.0002158
669 REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 34 3.161e-05 0.0002188
670 RESPONSE TO PROSTAGLANDIN 5 34 3.161e-05 0.0002188
671 REGULATION OF OSTEOBLAST DIFFERENTIATION 8 112 3.153e-05 0.0002188
672 ZYMOGEN ACTIVATION 8 112 3.153e-05 0.0002188
673 REGULATION OF PROTEIN STABILITY 11 221 3.247e-05 0.0002245
674 RESPONSE TO FATTY ACID 7 83 3.416e-05 0.0002358
675 REGULATION OF PROTEIN TARGETING 13 307 3.438e-05 0.000237
676 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 9 147 3.453e-05 0.0002377
677 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 16 448 3.485e-05 0.0002395
678 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 14 354 3.636e-05 0.0002495
679 RESPONSE TO TEMPERATURE STIMULUS 9 148 3.643e-05 0.0002496
680 BONE REMODELING 5 35 3.655e-05 0.0002501
681 REGULATION OF CELL MATURATION 4 18 3.727e-05 0.0002539
682 RESPONSE TO PLATELET DERIVED GROWTH FACTOR 4 18 3.727e-05 0.0002539
683 CELLULAR RESPONSE TO PROSTAGLANDIN E STIMULUS 4 18 3.727e-05 0.0002539
684 CELLULAR RESPONSE TO ALCOHOL 8 115 3.815e-05 0.0002595
685 EPHRIN RECEPTOR SIGNALING PATHWAY 7 85 3.987e-05 0.0002708
686 EMBRYONIC ORGAN DEVELOPMENT 15 406 4.185e-05 0.0002839
687 POSITIVE REGULATION OF GLUCOSE METABOLIC PROCESS 5 36 4.207e-05 0.0002849
688 REGULATION OF CELL CYCLE PROCESS 18 558 4.294e-05 0.0002904
689 VASCULOGENESIS 6 59 4.357e-05 0.0002943
690 MYELOID CELL DIFFERENTIATION 10 189 4.445e-05 0.0002997
691 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 7 87 4.634e-05 0.000312
692 KIDNEY VASCULATURE DEVELOPMENT 4 19 4.681e-05 0.000312
693 REGULATION OF NITRIC OXIDE SYNTHASE BIOSYNTHETIC PROCESS 4 19 4.681e-05 0.000312
694 POSITIVE REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 4 19 4.681e-05 0.000312
695 RENAL SYSTEM VASCULATURE DEVELOPMENT 4 19 4.681e-05 0.000312
696 MULTICELLULAR ORGANISMAL HOMEOSTASIS 12 272 4.65e-05 0.000312
697 STEM CELL DIFFERENTIATION 10 190 4.647e-05 0.000312
698 ASTROCYTE DEVELOPMENT 4 19 4.681e-05 0.000312
699 POSITIVE REGULATION OF PROTEOLYSIS 14 363 4.772e-05 0.0003177
700 CHONDROCYTE DIFFERENTIATION 6 60 4.798e-05 0.0003189
701 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO CELL PERIPHERY 5 37 4.821e-05 0.0003196
702 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 5 37 4.821e-05 0.0003196
703 REGULATION OF COAGULATION 7 88 4.988e-05 0.0003297
704 REGULATION OF STEM CELL PROLIFERATION 7 88 4.988e-05 0.0003297
705 REGULATION OF DENDRITE DEVELOPMENT 8 120 5.173e-05 0.0003414
706 CIRCULATORY SYSTEM PROCESS 14 366 5.215e-05 0.0003437
707 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 11 233 5.254e-05 0.0003453
708 RESPONSE TO TUMOR NECROSIS FACTOR 11 233 5.254e-05 0.0003453
709 CELLULAR RESPONSE TO HYDROGEN PEROXIDE 6 61 5.273e-05 0.0003461
710 PROTEIN LOCALIZATION TO NUCLEUS 9 156 5.499e-05 0.0003601
711 POSITIVE REGULATION OF ORGAN GROWTH 5 38 5.503e-05 0.0003601
712 MIDBRAIN DEVELOPMENT 7 90 5.764e-05 0.0003761
713 MESONEPHROS DEVELOPMENT 7 90 5.764e-05 0.0003761
714 EMBRYONIC HEMOPOIESIS 4 20 5.801e-05 0.0003765
715 AMELOGENESIS 4 20 5.801e-05 0.0003765
716 REGULATION OF NEURON PROJECTION REGENERATION 4 20 5.801e-05 0.0003765
717 POSITIVE REGULATION OF NUCLEAR DIVISION 6 62 5.786e-05 0.0003765
718 PROTEIN LOCALIZATION 38 1805 6.029e-05 0.0003907
719 RESPONSE TO PURINE CONTAINING COMPOUND 9 158 6.071e-05 0.0003929
720 CELLULAR RESPONSE TO LIGHT STIMULUS 7 91 6.187e-05 0.0003998
721 CELLULAR RESPONSE TO NUTRIENT 5 39 6.257e-05 0.0004038
722 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 10 199 6.858e-05 0.0004414
723 REGULATION OF ENDOCYTOSIS 10 199 6.858e-05 0.0004414
724 KIDNEY EPITHELIUM DEVELOPMENT 8 125 6.913e-05 0.0004443
725 REGULATION OF ACTIVATED T CELL PROLIFERATION 5 40 7.087e-05 0.0004549
726 ANATOMICAL STRUCTURE HOMEOSTASIS 12 285 7.279e-05 0.0004665
727 REGULATION OF WOUND HEALING 8 126 7.313e-05 0.0004681
728 POSITIVE REGULATION OF RESPONSE TO WOUNDING 9 162 7.366e-05 0.0004708
729 REGULATION OF CHEMOKINE PRODUCTION 6 65 7.565e-05 0.0004829
730 CELLULAR RESPONSE TO BIOTIC STIMULUS 9 163 7.724e-05 0.0004915
731 NEGATIVE REGULATION OF ION TRANSPORT 8 127 7.733e-05 0.0004915
732 RESPONSE TO TOPOLOGICALLY INCORRECT PROTEIN 9 163 7.724e-05 0.0004915
733 CELLULAR MACROMOLECULE LOCALIZATION 29 1234 7.817e-05 0.0004962
734 RESPONSE TO METAL ION 13 333 7.88e-05 0.0004995
735 POSITIVE REGULATION OF T CELL PROLIFERATION 7 95 8.142e-05 0.0005154
736 CELLULAR RESPONSE TO UV 6 66 8.247e-05 0.0005214
737 REGULATION OF SECRETION 20 699 8.523e-05 0.0005381
738 POSITIVE REGULATION OF PROTEIN AUTOPHOSPHORYLATION 4 22 8.61e-05 0.0005414
739 SOMATIC STEM CELL DIVISION 4 22 8.61e-05 0.0005414
740 ERK1 AND ERK2 CASCADE 4 22 8.61e-05 0.0005414
741 MYELOID LEUKOCYTE DIFFERENTIATION 7 96 8.702e-05 0.0005457
742 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE 7 96 8.702e-05 0.0005457
743 RESPONSE TO VIRUS 11 247 8.866e-05 0.0005552
744 REGULATION OF ENDOTHELIAL CELL APOPTOTIC PROCESS 5 42 9.002e-05 0.000563
745 REGULATION OF AUTOPHAGY 11 249 9.524e-05 0.0005948
746 LEARNING 8 131 9.616e-05 0.0005998
747 MULTICELLULAR ORGANISMAL RESPONSE TO STRESS 6 68 9.757e-05 0.0006077
748 CEREBRAL CORTEX CELL MIGRATION 5 43 0.000101 0.0006272
749 REGULATION OF INSULIN RECEPTOR SIGNALING PATHWAY 5 43 0.000101 0.0006272
750 B CELL ACTIVATION 8 132 0.0001014 0.0006292
751 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO STRESS 4 23 0.0001033 0.0006394
752 POSITIVE REGULATION OF NEUROLOGICAL SYSTEM PROCESS 4 23 0.0001033 0.0006394
753 NEGATIVE REGULATION OF CELL GROWTH 9 170 0.0001066 0.0006588
754 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 10 211 0.0001115 0.0006879
755 MESENCHYMAL CELL DIFFERENTIATION 8 134 0.0001126 0.0006924
756 INTERACTION WITH HOST 8 134 0.0001126 0.0006924
757 MITOTIC DNA INTEGRITY CHECKPOINT 7 100 0.0001127 0.0006924
758 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 5 44 0.0001129 0.0006931
759 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 6 70 0.0001148 0.0007037
760 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 9 172 0.0001166 0.0007136
761 STRIATED MUSCLE CELL DIFFERENTIATION 9 173 0.0001218 0.0007447
762 REGULATION OF MYELOID CELL APOPTOTIC PROCESS 4 24 0.000123 0.0007459
763 AXON REGENERATION 4 24 0.000123 0.0007459
764 POSITIVE REGULATION OF NUCLEOSIDE METABOLIC PROCESS 4 24 0.000123 0.0007459
765 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 4 24 0.000123 0.0007459
766 POSITIVE REGULATION OF RECEPTOR INTERNALIZATION 4 24 0.000123 0.0007459
767 POSITIVE REGULATION OF ATP METABOLIC PROCESS 4 24 0.000123 0.0007459
768 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 14 397 0.0001235 0.0007483
769 SKIN EPIDERMIS DEVELOPMENT 6 71 0.0001243 0.0007518
770 LUNG MORPHOGENESIS 5 45 0.0001259 0.0007598
771 ENDOCHONDRAL BONE MORPHOGENESIS 5 45 0.0001259 0.0007598
772 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 17 554 0.0001287 0.0007755
773 ACTIN FILAMENT BASED PROCESS 15 450 0.000132 0.0007946
774 REGULATION OF CYTOSKELETON ORGANIZATION 16 502 0.0001322 0.0007949
775 MEMBRANE ORGANIZATION 23 899 0.0001339 0.0008042
776 REGULATION OF MUSCLE TISSUE DEVELOPMENT 7 103 0.0001357 0.0008134
777 PEPTIDYL THREONINE MODIFICATION 5 46 0.00014 0.0008374
778 REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 5 46 0.00014 0.0008374
779 RESPONSE TO PROSTAGLANDIN E 4 25 0.0001451 0.0008612
780 ASSOCIATIVE LEARNING 6 73 0.000145 0.0008612
781 G1 DNA DAMAGE CHECKPOINT 6 73 0.000145 0.0008612
782 MITOTIC CELL CYCLE CHECKPOINT 8 139 0.0001453 0.0008612
783 CELLULAR RESPONSE TO KETONE 6 73 0.000145 0.0008612
784 HISTONE PHOSPHORYLATION 4 25 0.0001451 0.0008612
785 TYROSINE PHOSPHORYLATION OF STAT PROTEIN 3 10 0.0001449 0.0008612
786 POSITIVE REGULATION OF DEPHOSPHORYLATION 5 47 0.0001553 0.0009194
787 REGULATION OF DENDRITE MORPHOGENESIS 6 74 0.0001564 0.0009248
788 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 9 179 0.0001576 0.0009309
789 REGULATION OF WNT SIGNALING PATHWAY 12 310 0.0001605 0.0009455
790 EXOCYTOSIS 12 310 0.0001605 0.0009455
791 REGULATION OF GLUCOSE METABOLIC PROCESS 7 106 0.0001623 0.0009548
792 GRANULOCYTE MIGRATION 6 75 0.0001685 0.0009887
793 BIOMINERAL TISSUE DEVELOPMENT 6 75 0.0001685 0.0009887
794 REGULATION OF T HELPER CELL DIFFERENTIATION 4 26 0.0001701 0.0009916
795 REPLACEMENT OSSIFICATION 4 26 0.0001701 0.0009916
796 NEGATIVE REGULATION OF LIPID TRANSPORT 4 26 0.0001701 0.0009916
797 ENDOCHONDRAL OSSIFICATION 4 26 0.0001701 0.0009916
798 CELLULAR RESPONSE TO VITAMIN 4 26 0.0001701 0.0009916
799 RESPONSE TO AXON INJURY 5 48 0.0001718 0.0009995
800 COLUMNAR CUBOIDAL EPITHELIAL CELL DEVELOPMENT 5 48 0.0001718 0.0009995
801 RAS PROTEIN SIGNAL TRANSDUCTION 8 143 0.0001767 0.001026
802 REGULATION OF NITRIC OXIDE SYNTHASE ACTIVITY 5 49 0.0001897 0.001101
803 PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 7 109 0.0001931 0.001119
804 RESPONSE TO IONIZING RADIATION 8 145 0.0001944 0.001125
805 POSITIVE REGULATION OF HEART GROWTH 4 27 0.0001979 0.001141
806 PROSTATE GLAND GROWTH 3 11 0.0001976 0.001141
807 SUBSTRATE DEPENDENT CELL MIGRATION 4 27 0.0001979 0.001141
808 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 8 146 0.0002038 0.001173
809 ION HOMEOSTASIS 17 576 0.000204 0.001173
810 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION 7 110 0.0002043 0.001174
811 REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 6 78 0.0002092 0.001196
812 RENAL TUBULE DEVELOPMENT 6 78 0.0002092 0.001196
813 VISUAL BEHAVIOR 5 50 0.0002089 0.001196
814 POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 5 50 0.0002089 0.001196
815 REGULATION OF T CELL PROLIFERATION 8 147 0.0002135 0.001219
816 POSITIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 7 111 0.0002161 0.001232
817 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 11 274 0.0002199 0.001252
818 BONE MORPHOGENESIS 6 79 0.0002243 0.001276
819 NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR SIGNALING PATHWAY 4 28 0.000229 0.001296
820 LONG TERM MEMORY 4 28 0.000229 0.001296
821 MAMMARY GLAND DUCT MORPHOGENESIS 4 28 0.000229 0.001296
822 POSITIVE REGULATION OF PHOSPHATASE ACTIVITY 4 28 0.000229 0.001296
823 RESPONSE TO NICOTINE 5 51 0.0002296 0.001296
824 REGULATION OF INTERLEUKIN 12 PRODUCTION 5 51 0.0002296 0.001296
825 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 13 372 0.0002352 0.001327
826 REGULATION OF SYNAPSE ORGANIZATION 7 113 0.0002412 0.001356
827 POSITIVE REGULATION OF INFLAMMATORY RESPONSE 7 113 0.0002412 0.001356
828 PROTEIN HETEROOLIGOMERIZATION 7 113 0.0002412 0.001356
829 REGULATION OF IMMUNE EFFECTOR PROCESS 14 424 0.0002435 0.001366
830 POSITIVE REGULATION OF ENDOCYTOSIS 7 114 0.0002547 0.001428
831 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 9 191 0.000256 0.001434
832 POSITIVE REGULATION OF MYELOID CELL DIFFERENTIATION 6 81 0.0002573 0.001439
833 PRODUCTION OF MOLECULAR MEDIATOR INVOLVED IN INFLAMMATORY RESPONSE 3 12 0.0002613 0.001456
834 MAMMARY GLAND EPITHELIAL CELL PROLIFERATION 3 12 0.0002613 0.001456
835 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 3 12 0.0002613 0.001456
836 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 4 29 0.0002633 0.001462
837 STEM CELL DIVISION 4 29 0.0002633 0.001462
838 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 4 29 0.0002633 0.001462
839 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 7 115 0.0002687 0.00149
840 NEGATIVE REGULATION OF AUTOPHAGY 5 53 0.0002756 0.001523
841 MESONEPHRIC TUBULE MORPHOGENESIS 5 53 0.0002756 0.001523
842 KIDNEY MORPHOGENESIS 6 82 0.0002751 0.001523
843 POSITIVE REGULATION OF ION TRANSPORT 10 236 0.0002763 0.001525
844 DEVELOPMENTAL MATURATION 9 193 0.0002765 0.001525
845 NEGATIVE REGULATION OF PROTEOLYSIS 12 329 0.0002772 0.001526
846 MUSCLE CELL DIFFERENTIATION 10 237 0.0002858 0.001572
847 MACROMOLECULAR COMPLEX ASSEMBLY 30 1398 0.0002868 0.001576
848 CELL CYCLE CHECKPOINT 9 194 0.0002873 0.001576
849 HAIR CYCLE 6 83 0.0002938 0.001609
850 MOLTING CYCLE 6 83 0.0002938 0.001609
851 EAR DEVELOPMENT 9 195 0.0002984 0.001632
852 RESPONSE TO EPIDERMAL GROWTH FACTOR 4 30 0.0003013 0.001636
853 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 4 30 0.0003013 0.001636
854 NEGATIVE REGULATION OF TOR SIGNALING 4 30 0.0003013 0.001636
855 REGULATION OF MITOCHONDRIAL MEMBRANE POTENTIAL 5 54 0.000301 0.001636
856 MYD88 INDEPENDENT TOLL LIKE RECEPTOR SIGNALING PATHWAY 4 30 0.0003013 0.001636
857 OSTEOCLAST DIFFERENTIATION 4 30 0.0003013 0.001636
858 PROTEIN IMPORT 8 155 0.000306 0.00166
859 SINGLE ORGANISM BIOSYNTHETIC PROCESS 29 1340 0.0003177 0.001721
860 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 9 197 0.0003217 0.00174
861 REGULATION OF TRANSPORTER ACTIVITY 9 198 0.0003338 0.001804
862 TOLL LIKE RECEPTOR SIGNALING PATHWAY 6 85 0.0003344 0.001805
863 NEURONAL STEM CELL DIVISION 3 13 0.000337 0.001813
864 INDUCTION OF POSITIVE CHEMOTAXIS 3 13 0.000337 0.001813
865 NEUROBLAST DIVISION 3 13 0.000337 0.001813
866 SKELETAL MUSCLE CONTRACTION 4 31 0.000343 0.001841
867 LIPOPOLYSACCHARIDE MEDIATED SIGNALING PATHWAY 4 31 0.000343 0.001841
868 POSITIVE REGULATION OF B CELL ACTIVATION 6 86 0.0003563 0.00191
869 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 19 720 0.0003572 0.001912
870 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 6 87 0.0003792 0.002012
871 NEGATIVE REGULATION OF TRANSMEMBRANE TRANSPORT 6 87 0.0003792 0.002012
872 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 6 87 0.0003792 0.002012
873 VIRAL ENTRY INTO HOST CELL 6 87 0.0003792 0.002012
874 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 6 87 0.0003792 0.002012
875 MOVEMENT IN HOST ENVIRONMENT 6 87 0.0003792 0.002012
876 ENTRY INTO HOST 6 87 0.0003792 0.002012
877 ENTRY INTO HOST CELL 6 87 0.0003792 0.002012
878 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 7 122 0.0003853 0.002042
879 POSITIVE REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 5 57 0.0003881 0.002048
880 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 4 32 0.0003886 0.002048
881 REGULATION OF ACTIN CYTOSKELETON REORGANIZATION 4 32 0.0003886 0.002048
882 POSITIVE REGULATION OF MULTICELLULAR ORGANISM GROWTH 4 32 0.0003886 0.002048
883 NEGATIVE REGULATION OF SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 4 32 0.0003886 0.002048
884 REGULATION OF INFLAMMATORY RESPONSE 11 294 0.0004007 0.002109
885 LEUKOCYTE PROLIFERATION 6 88 0.0004033 0.00212
886 DIVALENT INORGANIC CATION HOMEOSTASIS 12 343 0.0004036 0.00212
887 EPITHELIAL CELL CELL ADHESION 3 14 0.0004255 0.002222
888 PROTEIN HETEROTRIMERIZATION 3 14 0.0004255 0.002222
889 NEGATIVE REGULATION OF MYELOID CELL APOPTOTIC PROCESS 3 14 0.0004255 0.002222
890 BONE MATURATION 3 14 0.0004255 0.002222
891 POSITIVE REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION INVOLVED IN PHOSPHOLIPASE C ACTIVATING G PROTEIN COUPLED SIGNALING PATHWAY 3 14 0.0004255 0.002222
892 RESPONSE TO VITAMIN D 4 33 0.0004385 0.00228
893 NEURON PROJECTION REGENERATION 4 33 0.0004385 0.00228
894 REGULATION OF BONE RESORPTION 4 33 0.0004385 0.00228
895 CYTOPLASMIC PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 4 33 0.0004385 0.00228
896 POSITIVE REGULATION OF DNA BIOSYNTHETIC PROCESS 5 59 0.000456 0.002368
897 CELLULAR PROCESS INVOLVED IN REPRODUCTION IN MULTICELLULAR ORGANISM 10 252 0.0004639 0.002407
898 VESICLE MEDIATED TRANSPORT 27 1239 0.000466 0.002415
899 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 7 126 0.0004683 0.002424
900 ENSHEATHMENT OF NEURONS 6 91 0.0004828 0.002493
901 AXON ENSHEATHMENT 6 91 0.0004828 0.002493
902 ENDOCYTOSIS 15 509 0.0004902 0.002529
903 REGULATION OF MONOOXYGENASE ACTIVITY 5 60 0.0004931 0.002529
904 REGULATION OF SMOOTH MUSCLE CONTRACTION 5 60 0.0004931 0.002529
905 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 7 127 0.0004911 0.002529
906 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 4 34 0.0004927 0.002529
907 LEUKOCYTE HOMEOSTASIS 5 60 0.0004931 0.002529
908 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 12 351 0.0004956 0.00254
909 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 8 167 0.000504 0.00258
910 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 12 352 0.0005083 0.002599
911 NEGATIVE REGULATION OF DENDRITE MORPHOGENESIS 3 15 0.0005276 0.002689
912 RESPONSE TO VITAMIN E 3 15 0.0005276 0.002689
913 T CELL LINEAGE COMMITMENT 3 15 0.0005276 0.002689
914 POSITIVE REGULATION OF PROTEIN SECRETION 9 211 0.0005302 0.002696
915 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 9 211 0.0005302 0.002696
916 NUCLEAR IMPORT 7 129 0.0005393 0.00274
917 PROTEIN TARGETING 13 406 0.0005404 0.002742
918 NEPHRON EPITHELIUM DEVELOPMENT 6 93 0.0005423 0.002749
919 HEART MORPHOGENESIS 9 212 0.0005486 0.002777
920 CELL DIVISION 14 460 0.00055 0.002781
921 NEGATIVE REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 4 35 0.0005516 0.002781
922 RESPONSE TO MINERALOCORTICOID 4 35 0.0005516 0.002781
923 RESPONSE TO IRON ION 4 35 0.0005516 0.002781
924 FOREBRAIN CELL MIGRATION 5 62 0.000574 0.002885
925 REGULATION OF DNA BIOSYNTHETIC PROCESS 6 94 0.0005741 0.002885
926 REGULATION OF TISSUE REMODELING 5 62 0.000574 0.002885
927 NEGATIVE REGULATION OF CELL CYCLE PROCESS 9 214 0.0005869 0.002946
928 PROTEIN STABILIZATION 7 131 0.0005913 0.002965
929 REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 4 36 0.0006153 0.003075
930 OLFACTORY LOBE DEVELOPMENT 4 36 0.0006153 0.003075
931 T CELL SELECTION 4 36 0.0006153 0.003075
932 REGULATION OF OSTEOCLAST DIFFERENTIATION 5 63 0.000618 0.003082
933 REGULATION OF MUSCLE ADAPTATION 5 63 0.000618 0.003082
934 IN UTERO EMBRYONIC DEVELOPMENT 11 311 0.0006402 0.003188
935 POSITIVE REGULATION OF PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 3 16 0.0006441 0.003188
936 POSITIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 3 16 0.0006441 0.003188
937 CARDIOCYTE DIFFERENTIATION 6 96 0.000642 0.003188
938 TOR SIGNALING 3 16 0.0006441 0.003188
939 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 3 16 0.0006441 0.003188
940 REGULATION OF DEVELOPMENTAL PIGMENTATION 3 16 0.0006441 0.003188
941 POSITIVE REGULATION OF PURINE NUCLEOTIDE METABOLIC PROCESS 7 133 0.0006471 0.003197
942 POSITIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 7 133 0.0006471 0.003197
943 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 9 218 0.0006701 0.003306
944 POSITIVE REGULATION OF B CELL PROLIFERATION 4 37 0.000684 0.003361
945 REGULATION OF RECEPTOR INTERNALIZATION 4 37 0.000684 0.003361
946 REGULATION OF PROTEIN AUTOPHOSPHORYLATION 4 37 0.000684 0.003361
947 POSITIVE REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 4 37 0.000684 0.003361
948 NEGATIVE REGULATION OF AXONOGENESIS 5 65 0.0007136 0.003502
949 STRIATED MUSCLE CONTRACTION 6 99 0.0007553 0.003703
950 RESPONSE TO TESTOSTERONE 4 38 0.000758 0.003705
951 BONE MINERALIZATION 4 38 0.000758 0.003705
952 REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 4 38 0.000758 0.003705
953 NEURAL NUCLEUS DEVELOPMENT 5 66 0.0007653 0.003737
954 BRANCH ELONGATION OF AN EPITHELIUM 3 17 0.0007759 0.003768
955 NEGATIVE REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA 3 17 0.0007759 0.003768
956 NEGATIVE REGULATION OF LIPID STORAGE 3 17 0.0007759 0.003768
957 MAMMARY GLAND ALVEOLUS DEVELOPMENT 3 17 0.0007759 0.003768
958 MAMMARY GLAND LOBULE DEVELOPMENT 3 17 0.0007759 0.003768
959 MULTICELLULAR ORGANISM REPRODUCTION 19 768 0.00078 0.003784
960 PLACENTA DEVELOPMENT 7 138 0.0008053 0.003903
961 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 5 67 0.0008198 0.003969
962 TRABECULA MORPHOGENESIS 4 39 0.0008375 0.004034
963 REGULATION OF CELL ADHESION MEDIATED BY INTEGRIN 4 39 0.0008375 0.004034
964 REGULATION OF GRANULOCYTE CHEMOTAXIS 4 39 0.0008375 0.004034
965 EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 4 39 0.0008375 0.004034
966 LONG TERM SYNAPTIC POTENTIATION 4 39 0.0008375 0.004034
967 REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 6 101 0.000839 0.004037
968 REGULATION OF TRANSMEMBRANE TRANSPORT 13 426 0.0008428 0.004051
969 REGULATION OF ALPHA BETA T CELL ACTIVATION 5 68 0.0008771 0.004203
970 CARDIAC MUSCLE TISSUE DEVELOPMENT 7 140 0.0008764 0.004203
971 POSITIVE REGULATION OF INTERLEUKIN 6 PRODUCTION 5 68 0.0008771 0.004203
972 NEGATIVE REGULATION OF IMMUNE EFFECTOR PROCESS 6 102 0.0008835 0.004229
973 MUSCLE TISSUE DEVELOPMENT 10 275 0.0009094 0.004349
974 REGULATION OF MITOCHONDRIAL DEPOLARIZATION 3 18 0.0009236 0.004376
975 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 3 18 0.0009236 0.004376
976 MAMMARY GLAND MORPHOGENESIS 4 40 0.0009227 0.004376
977 ORGAN MATURATION 3 18 0.0009236 0.004376
978 ENDOCRINE PANCREAS DEVELOPMENT 4 40 0.0009227 0.004376
979 OVULATION 3 18 0.0009236 0.004376
980 RESPONSE TO CAFFEINE 3 18 0.0009236 0.004376
981 POSITIVE REGULATION OF T HELPER CELL DIFFERENTIATION 3 18 0.0009236 0.004376
982 MUSCLE CELL MIGRATION 3 18 0.0009236 0.004376
983 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 6 103 0.0009298 0.004401
984 INTRACELLULAR PROTEIN TRANSPORT 19 781 0.0009508 0.004496
985 REGULATION OF INTERLEUKIN 6 PRODUCTION 6 104 0.0009779 0.004619
986 POSITIVE REGULATION OF TYPE I INTERFERON PRODUCTION 5 70 0.001001 0.004717
987 I KAPPAB KINASE NF KAPPAB SIGNALING 5 70 0.001001 0.004717
988 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 4 41 0.001014 0.004746
989 MULTICELLULAR ORGANISMAL MOVEMENT 4 41 0.001014 0.004746
990 REGULATION OF MEMBRANE DEPOLARIZATION 4 41 0.001014 0.004746
991 CELLULAR RESPONSE TO ESTROGEN STIMULUS 4 41 0.001014 0.004746
992 MUSCULOSKELETAL MOVEMENT 4 41 0.001014 0.004746
993 PROSTATE GLAND DEVELOPMENT 4 41 0.001014 0.004746
994 LACTATION 4 41 0.001014 0.004746
995 EPITHELIAL CELL DEVELOPMENT 8 186 0.001019 0.004766
996 BODY FLUID SECRETION 5 71 0.001067 0.004985
997 NEUROLOGICAL SYSTEM PROCESS 26 1242 0.001072 0.005002
998 NEGATIVE REGULATION OF MAPK CASCADE 7 145 0.001076 0.005018
999 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 6 106 0.00108 0.005024
1000 FAT CELL DIFFERENTIATION 6 106 0.00108 0.005024
1001 MACROPHAGE DIFFERENTIATION 3 19 0.001088 0.005057
1002 MUSCLE SYSTEM PROCESS 10 282 0.0011 0.005106
1003 EYE PHOTORECEPTOR CELL DIFFERENTIATION 4 42 0.001111 0.005134
1004 REGULATION OF BONE REMODELING 4 42 0.001111 0.005134
1005 REGULATION OF CELLULAR CARBOHYDRATE CATABOLIC PROCESS 4 42 0.001111 0.005134
1006 REGULATION OF HEART GROWTH 4 42 0.001111 0.005134
1007 REGULATION OF CARBOHYDRATE CATABOLIC PROCESS 4 42 0.001111 0.005134
1008 DNA INTEGRITY CHECKPOINT 7 146 0.00112 0.005171
1009 RESPONSE TO ELECTRICAL STIMULUS 4 43 0.001215 0.005568
1010 PANCREAS DEVELOPMENT 5 73 0.00121 0.005568
1011 REGULATION OF GLYCOPROTEIN METABOLIC PROCESS 4 43 0.001215 0.005568
1012 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 4 43 0.001215 0.005568
1013 MYELOID LEUKOCYTE MEDIATED IMMUNITY 4 43 0.001215 0.005568
1014 MALE SEX DIFFERENTIATION 7 148 0.001212 0.005568
1015 ACUTE PHASE RESPONSE 4 43 0.001215 0.005568
1016 HYPEROSMOTIC RESPONSE 3 20 0.00127 0.005798
1017 NEGATIVE REGULATION OF CELL JUNCTION ASSEMBLY 3 20 0.00127 0.005798
1018 NEGATIVE REGULATION OF CELL CYCLE ARREST 3 20 0.00127 0.005798
1019 RESPONSE TO MUSCLE ACTIVITY 3 20 0.00127 0.005798
1020 CARDIAC MUSCLE CELL DIFFERENTIATION 5 74 0.001286 0.005866
1021 ESTABLISHMENT OF LOCALIZATION IN CELL 32 1676 0.001314 0.005988
1022 AUTOPHAGY 12 394 0.001348 0.006139
1023 CELLULAR GLUCOSE HOMEOSTASIS 5 75 0.001366 0.0062
1024 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 5 75 0.001366 0.0062
1025 POSITIVE REGULATION OF AUTOPHAGY 5 75 0.001366 0.0062
1026 EAR MORPHOGENESIS 6 112 0.001435 0.006508
1027 SUBSTANTIA NIGRA DEVELOPMENT 4 45 0.001442 0.006532
1028 REGULATION OF CELLULAR RESPONSE TO HEAT 5 76 0.001449 0.006559
1029 POSITIVE T CELL SELECTION 3 21 0.00147 0.006639
1030 POSITIVE REGULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 3 21 0.00147 0.006639
1031 DEVELOPMENTAL CELL GROWTH 5 77 0.001536 0.006933
1032 REGULATION OF EMBRYONIC DEVELOPMENT 6 114 0.001571 0.007084
1033 SENSORY PERCEPTION OF MECHANICAL STIMULUS 7 155 0.001582 0.007127
1034 RESPONSE TO INTERLEUKIN 1 6 115 0.001643 0.007379
1035 REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 7 156 0.001642 0.007379
1036 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 7 156 0.001642 0.007379
1037 REGULATION OF ION HOMEOSTASIS 8 201 0.00167 0.007485
1038 SKELETAL SYSTEM MORPHOGENESIS 8 201 0.00167 0.007485
1039 ACTIVATION OF PROTEIN KINASE B ACTIVITY 3 22 0.001688 0.007552
1040 CELLULAR RESPONSE TO INTERLEUKIN 6 3 22 0.001688 0.007552
1041 THYMUS DEVELOPMENT 4 47 0.001697 0.007563
1042 POSITIVE REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 4 47 0.001697 0.007563
1043 WNT SIGNALING PATHWAY 11 351 0.001697 0.007563
1044 POSITIVE REGULATION OF GLIOGENESIS 4 47 0.001697 0.007563
1045 REGULATION OF SYNAPSE ASSEMBLY 5 79 0.001722 0.007667
1046 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 8 203 0.001777 0.007897
1047 NEGATIVE REGULATION OF CATABOLIC PROCESS 8 203 0.001777 0.007897
1048 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 4 48 0.001836 0.008142
1049 DIGESTIVE TRACT MORPHOGENESIS 4 48 0.001836 0.008142
1050 MULTI ORGANISM REPRODUCTIVE PROCESS 20 891 0.001839 0.008149
1051 SECOND MESSENGER MEDIATED SIGNALING 7 160 0.001896 0.008395
1052 METANEPHROS DEVELOPMENT 5 81 0.001923 0.008469
1053 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 23 0.001926 0.008469
1054 RESPONSE TO MAGNESIUM ION 3 23 0.001926 0.008469
1055 REGULATION OF OSTEOBLAST PROLIFERATION 3 23 0.001926 0.008469
1056 LEUKOCYTE APOPTOTIC PROCESS 3 23 0.001926 0.008469
1057 TRABECULA FORMATION 3 23 0.001926 0.008469
1058 POSITIVE REGULATION OF COLLAGEN METABOLIC PROCESS 3 23 0.001926 0.008469
1059 GLUCOSE METABOLIC PROCESS 6 119 0.001955 0.008589
1060 REGULATION OF NUCLEOSIDE METABOLIC PROCESS 4 49 0.001982 0.008692
1061 REGULATION OF ATP METABOLIC PROCESS 4 49 0.001982 0.008692
1062 NEGATIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 5 82 0.002031 0.008896
1063 VASCULAR PROCESS IN CIRCULATORY SYSTEM 7 163 0.002107 0.009222
1064 CYTOSKELETON ORGANIZATION 19 838 0.002131 0.009254
1065 LYMPHOCYTE HOMEOSTASIS 4 50 0.002136 0.009254
1066 REGULATION OF COENZYME METABOLIC PROCESS 4 50 0.002136 0.009254
1067 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 8 209 0.002131 0.009254
1068 FACE DEVELOPMENT 4 50 0.002136 0.009254
1069 REGULATION OF B CELL ACTIVATION 6 121 0.002127 0.009254
1070 PHOTORECEPTOR CELL DIFFERENTIATION 4 50 0.002136 0.009254
1071 REGULATION OF TUMOR NECROSIS FACTOR MEDIATED SIGNALING PATHWAY 4 50 0.002136 0.009254
1072 RESPONSE TO GAMMA RADIATION 4 50 0.002136 0.009254
1073 REGULATION OF COFACTOR METABOLIC PROCESS 4 50 0.002136 0.009254
1074 NEGATIVE REGULATION OF IMMUNE RESPONSE 6 121 0.002127 0.009254
1075 REGULATION OF ERBB SIGNALING PATHWAY 5 83 0.002142 0.009262
1076 PHOSPHOLIPASE C ACTIVATING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 5 83 0.002142 0.009262
1077 FOCAL ADHESION ASSEMBLY 3 24 0.002183 0.00938
1078 NEGATIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 3 24 0.002183 0.00938
1079 POSITIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 3 24 0.002183 0.00938
1080 POSITIVE REGULATION OF OSTEOCLAST DIFFERENTIATION 3 24 0.002183 0.00938
1081 POSITIVE REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 3 24 0.002183 0.00938
1082 POSITIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 3 24 0.002183 0.00938
1083 CELL SUBSTRATE ADHERENS JUNCTION ASSEMBLY 3 24 0.002183 0.00938
1084 CELLULAR RESPONSE TO TOPOLOGICALLY INCORRECT PROTEIN 6 122 0.002217 0.009515
1085 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 5 84 0.002258 0.009682
1086 MITOCHONDRION ORGANIZATION 15 594 0.002278 0.009759
1087 POSITIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 4 51 0.002298 0.00982
1088 NEGATIVE REGULATION OF CALCIUM ION TRANSPORT 4 51 0.002298 0.00982
1089 POSITIVE REGULATION OF ALPHA BETA T CELL ACTIVATION 4 51 0.002298 0.00982
1090 REGULATION OF ACTIN FILAMENT BASED PROCESS 10 312 0.002318 0.009897
1091 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 7 166 0.002335 0.009957
NumGOOverlapSizeP ValueAdj. P Value
1 RECEPTOR BINDING 83 1476 3.486e-38 3.239e-35
2 KINASE ACTIVITY 63 842 2.449e-35 1.138e-32
3 PROTEIN KINASE ACTIVITY 54 640 1.033e-32 3.199e-30
4 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 64 992 3.873e-32 8.996e-30
5 PROTEIN TYROSINE KINASE ACTIVITY 30 176 2.783e-27 5.17e-25
6 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 22 70 1.228e-26 1.902e-24
7 MOLECULAR FUNCTION REGULATOR 66 1353 4.147e-26 5.504e-24
8 GROWTH FACTOR ACTIVITY 27 160 1.646e-24 1.911e-22
9 GROWTH FACTOR BINDING 24 123 1.786e-23 1.843e-21
10 KINASE BINDING 43 606 5.91e-23 5.328e-21
11 ENZYME BINDING 70 1737 6.309e-23 5.328e-21
12 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 16 43 4.655e-21 3.604e-19
13 GROWTH FACTOR RECEPTOR BINDING 22 129 2.956e-20 2.113e-18
14 SIGNAL TRANSDUCER ACTIVITY 66 1731 3.189e-20 2.116e-18
15 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 16 51 1.167e-19 7.226e-18
16 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 17 64 2.023e-19 1.174e-17
17 PROTEIN COMPLEX BINDING 46 935 4.09e-18 2.235e-16
18 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 25 228 4.568e-18 2.358e-16
19 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 17 81 1.601e-17 7.829e-16
20 INTEGRIN BINDING 17 105 1.624e-15 7.546e-14
21 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 25 303 3.908e-15 1.729e-13
22 MACROMOLECULAR COMPLEX BINDING 51 1399 1.092e-14 4.611e-13
23 KINASE REGULATOR ACTIVITY 19 186 1.976e-13 7.648e-12
24 CELL ADHESION MOLECULE BINDING 19 186 1.976e-13 7.648e-12
25 PLATELET DERIVED GROWTH FACTOR RECEPTOR BINDING 8 15 1.056e-12 3.924e-11
26 HEPARIN BINDING 17 157 1.477e-12 5.276e-11
27 PROTEIN PHOSPHATASE BINDING 15 120 3.874e-12 1.333e-10
28 ENZYME REGULATOR ACTIVITY 38 959 4.141e-12 1.374e-10
29 COLLAGEN BINDING 12 65 5.033e-12 1.612e-10
30 GLYCOSAMINOGLYCAN BINDING 18 205 1.148e-11 3.556e-10
31 PHOSPHATASE BINDING 16 162 2.812e-11 8.426e-10
32 SULFUR COMPOUND BINDING 18 234 1.038e-10 3.014e-09
33 SIGNALING RECEPTOR ACTIVITY 44 1393 1.213e-10 3.416e-09
34 PROTEIN SERINE THREONINE KINASE ACTIVITY 24 445 1.268e-10 3.465e-09
35 RIBONUCLEOTIDE BINDING 52 1860 1.496e-10 3.818e-09
36 ADENYL NUCLEOTIDE BINDING 46 1514 1.521e-10 3.818e-09
37 CYTOKINE RECEPTOR BINDING 19 271 1.519e-10 3.818e-09
38 EXTRACELLULAR MATRIX BINDING 10 51 1.666e-10 4.072e-09
39 RECEPTOR ACTIVITY 48 1649 2.377e-10 5.662e-09
40 PROTEIN HETERODIMERIZATION ACTIVITY 24 468 3.527e-10 8.191e-09
41 FIBROBLAST GROWTH FACTOR RECEPTOR BINDING 8 28 4.515e-10 1.023e-08
42 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 11 76 6.172e-10 1.365e-08
43 PLATELET DERIVED GROWTH FACTOR BINDING 6 11 6.911e-10 1.459e-08
44 INSULIN RECEPTOR SUBSTRATE BINDING 6 11 6.911e-10 1.459e-08
45 PROTEIN DIMERIZATION ACTIVITY 38 1149 7.838e-10 1.618e-08
46 IDENTICAL PROTEIN BINDING 39 1209 9.209e-10 1.86e-08
47 PROTEIN PHOSPHATASE TYPE 2A REGULATOR ACTIVITY 7 21 1.696e-09 3.351e-08
48 CAMP RESPONSE ELEMENT BINDING 6 13 2.521e-09 4.879e-08
49 CYTOKINE RECEPTOR ACTIVITY 11 89 3.477e-09 6.593e-08
50 NEUROTROPHIN RECEPTOR BINDING 6 14 4.371e-09 8.122e-08
51 CYTOKINE BINDING 11 92 4.974e-09 9.06e-08
52 PROTEIN DOMAIN SPECIFIC BINDING 26 624 5.083e-09 9.081e-08
53 INSULIN LIKE GROWTH FACTOR RECEPTOR BINDING 6 15 7.219e-09 1.265e-07
54 FIBRONECTIN BINDING 7 28 1.618e-08 2.784e-07
55 KINASE ACTIVATOR ACTIVITY 8 62 3.573e-07 6.036e-06
56 CHEMOATTRACTANT ACTIVITY 6 27 3.827e-07 6.35e-06
57 RECEPTOR SIGNALING PROTEIN ACTIVITY 12 172 4.254e-07 6.933e-06
58 CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE REGULATOR ACTIVITY 6 28 4.827e-07 7.732e-06
59 PHOSPHATIDYLINOSITOL 3 KINASE BINDING 6 30 7.471e-07 1.157e-05
60 LAMININ BINDING 6 30 7.471e-07 1.157e-05
61 PROTEIN BINDING INVOLVED IN CELL ADHESION 5 17 8.174e-07 1.245e-05
62 INSULIN RECEPTOR BINDING 6 32 1.12e-06 1.678e-05
63 PROTEIN TYROSINE KINASE BINDING 7 54 1.903e-06 2.807e-05
64 PROTEIN HOMODIMERIZATION ACTIVITY 23 722 4.394e-06 6.378e-05
65 BIOACTIVE LIPID RECEPTOR ACTIVITY 4 14 1.262e-05 0.0001803
66 PROTEASE BINDING 8 104 1.84e-05 0.000259
67 UBIQUITIN LIKE PROTEIN LIGASE BINDING 12 264 3.48e-05 0.0004826
68 PEPTIDE HORMONE BINDING 5 36 4.207e-05 0.0005747
69 PHOSPHATASE REGULATOR ACTIVITY 7 87 4.634e-05 0.0006212
70 HISTONE KINASE ACTIVITY 4 19 4.681e-05 0.0006212
71 PROTEIN SERINE THREONINE TYROSINE KINASE ACTIVITY 5 39 6.257e-05 0.0008146
72 ENZYME ACTIVATOR ACTIVITY 16 471 6.314e-05 0.0008146
73 FIBROBLAST GROWTH FACTOR BINDING 4 23 0.0001033 0.001315
74 VIRUS RECEPTOR ACTIVITY 6 70 0.0001148 0.001441
75 EPHRIN RECEPTOR BINDING 4 24 0.000123 0.001523
76 NON MEMBRANE SPANNING PROTEIN TYROSINE KINASE ACTIVITY 5 46 0.00014 0.001712
77 HISTONE DEACETYLASE BINDING 7 105 0.000153 0.001846
78 PROTEIN KINASE C ACTIVITY 3 16 0.0006441 0.007574
79 PHOSPHATIDYLINOSITOL PHOSPHATE KINASE ACTIVITY 3 16 0.0006441 0.007574
80 HORMONE BINDING 5 65 0.0007136 0.008287
81 AMIDE BINDING 10 272 0.0008366 0.009595
NumGOOverlapSizeP ValueAdj. P Value
1 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 16 30 2.891e-24 1.688e-21
2 EXTRACELLULAR MATRIX 38 426 8.125e-24 2.373e-21
3 EXTRACELLULAR MATRIX COMPONENT 24 125 2.69e-23 5.236e-21
4 RECEPTOR COMPLEX 33 327 1.966e-22 2.87e-20
5 CELL SURFACE 46 757 9.009e-22 1.052e-19
6 PROTEINACEOUS EXTRACELLULAR MATRIX 33 356 2.865e-21 2.789e-19
7 PLASMA MEMBRANE RECEPTOR COMPLEX 25 175 6.525e-21 5.444e-19
8 CELL SUBSTRATE JUNCTION 33 398 9.13e-20 6.665e-18
9 BASEMENT MEMBRANE 19 93 3.288e-19 2.133e-17
10 SIDE OF MEMBRANE 33 428 8.416e-19 4.915e-17
11 PLASMA MEMBRANE PROTEIN COMPLEX 33 510 1.586e-16 8.42e-15
12 COMPLEX OF COLLAGEN TRIMERS 11 23 2.414e-16 1.175e-14
13 ANCHORING JUNCTION 32 489 3.46e-16 1.554e-14
14 INTRINSIC COMPONENT OF PLASMA MEMBRANE 57 1649 1.988e-15 8.293e-14
15 MEMBRANE PROTEIN COMPLEX 42 1020 6.948e-14 2.705e-12
16 MEMBRANE REGION 44 1134 1.262e-13 4.605e-12
17 TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS 21 237 1.713e-13 5.883e-12
18 CELL JUNCTION 44 1151 2.11e-13 6.847e-12
19 INTRACELLULAR VESICLE 46 1259 2.708e-13 8.324e-12
20 EXTRINSIC COMPONENT OF MEMBRANE 21 252 5.697e-13 1.664e-11
21 PROTEIN KINASE COMPLEX 14 90 9.57e-13 2.661e-11
22 CYTOPLASMIC SIDE OF MEMBRANE 17 170 5.413e-12 1.437e-10
23 PLASMA MEMBRANE REGION 37 929 7.135e-12 1.812e-10
24 COLLAGEN TRIMER 13 88 1.252e-11 3.046e-10
25 PROTEIN PHOSPHATASE TYPE 2A COMPLEX 8 20 1.972e-11 4.607e-10
26 EXTRACELLULAR SPACE 45 1376 2.259e-11 5.075e-10
27 BASAL LAMINA 8 21 3.156e-11 6.827e-10
28 EXTRINSIC COMPONENT OF CYTOPLASMIC SIDE OF PLASMA MEMBRANE 13 98 5.092e-11 1.062e-09
29 CATALYTIC COMPLEX 37 1038 1.71e-10 3.444e-09
30 EXTRINSIC COMPONENT OF PLASMA MEMBRANE 14 136 2.897e-10 5.64e-09
31 MEMBRANE MICRODOMAIN 19 288 4.266e-10 8.037e-09
32 EXTERNAL SIDE OF PLASMA MEMBRANE 17 238 1.097e-09 2.002e-08
33 PHOSPHATIDYLINOSITOL 3 KINASE COMPLEX 7 20 1.141e-09 2.019e-08
34 VESICLE LUMEN 12 106 1.859e-09 3.193e-08
35 ENDOPLASMIC RETICULUM LUMEN 15 201 5.96e-09 9.944e-08
36 PLATELET ALPHA GRANULE 10 75 8.606e-09 1.396e-07
37 CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 7 31 3.495e-08 5.517e-07
38 PERINUCLEAR REGION OF CYTOPLASM 25 642 3.863e-08 5.937e-07
39 PHOSPHATASE COMPLEX 8 48 4.546e-08 6.637e-07
40 HETEROTRIMERIC G PROTEIN COMPLEX 7 32 4.433e-08 6.637e-07
41 PLATELET ALPHA GRANULE LUMEN 8 55 1.374e-07 1.957e-06
42 CYTOPLASMIC VESICLE PART 23 601 1.912e-07 2.659e-06
43 CELL PROJECTION 43 1786 5.717e-07 7.764e-06
44 CELL LEADING EDGE 16 350 1.589e-06 2.109e-05
45 LEADING EDGE MEMBRANE 10 134 2.165e-06 2.81e-05
46 RUFFLE MEMBRANE 8 80 2.59e-06 3.288e-05
47 SECRETORY GRANULE LUMEN 8 85 4.104e-06 5.099e-05
48 PLASMA MEMBRANE RAFT 8 86 4.483e-06 5.454e-05
49 NEURON PART 32 1265 7.402e-06 8.822e-05
50 SECRETORY GRANULE 15 352 7.919e-06 9.249e-05
51 SYNAPSE 23 754 8.904e-06 0.000102
52 TRANSFERASE COMPLEX 22 703 9.485e-06 0.0001065
53 ENDOPLASMIC RETICULUM 37 1631 1.552e-05 0.000171
54 PIGMENT GRANULE 8 103 1.715e-05 0.0001854
55 BASAL PART OF CELL 6 51 1.872e-05 0.0001988
56 CELL PROJECTION MEMBRANE 13 298 2.524e-05 0.0002632
57 ENDOCYTIC VESICLE 12 256 2.575e-05 0.0002638
58 CELL PROJECTION PART 25 946 4.002e-05 0.000403
59 SECRETORY VESICLE 16 461 4.901e-05 0.0004851
60 RUFFLE 9 156 5.499e-05 0.0005352
61 VACUOLE 28 1180 8.907e-05 0.0008528
62 SOMATODENDRITIC COMPARTMENT 19 650 9.753e-05 0.0009187
63 NEURON PROJECTION 24 942 0.0001014 0.0009397
64 LAMELLIPODIUM 9 172 0.0001166 0.001064
65 ENDOPLASMIC RETICULUM PART 27 1163 0.0001715 0.001541
66 IKAPPAB KINASE COMPLEX 3 11 0.0001976 0.001748
67 BANDED COLLAGEN FIBRIL 3 12 0.0002613 0.002278
68 NEUROMUSCULAR JUNCTION 5 54 0.000301 0.002585
69 BASAL PLASMA MEMBRANE 4 33 0.0004385 0.003711
70 BASOLATERAL PLASMA MEMBRANE 9 211 0.0005302 0.004423
71 FILOPODIUM MEMBRANE 3 18 0.0009236 0.007597
72 POSTSYNAPSE 12 378 0.000947 0.007681
73 LAMELLIPODIUM MEMBRANE 3 19 0.001088 0.008704
74 ENDOSOME 19 793 0.001136 0.008966
75 PERIKARYON 6 108 0.00119 0.009264

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04151_PI3K_AKT_signaling_pathway 218 351 0 0
2 hsa04510_Focal_adhesion 83 200 4.944e-114 4.449e-112
3 hsa04014_Ras_signaling_pathway 79 236 3.835e-99 2.301e-97
4 hsa04512_ECM.receptor_interaction 45 85 7.868e-67 3.541e-65
5 hsa04810_Regulation_of_actin_cytoskeleton 55 214 1.127e-60 4.057e-59
6 hsa04722_Neurotrophin_signaling_pathway 34 127 4.86e-38 1.458e-36
7 hsa04150_mTOR_signaling_pathway 24 52 7.069e-34 1.818e-32
8 hsa04630_Jak.STAT_signaling_pathway 33 155 2.543e-33 5.722e-32
9 hsa04062_Chemokine_signaling_pathway 35 189 4.698e-33 9.395e-32
10 hsa04010_MAPK_signaling_pathway 39 268 1.416e-32 2.549e-31
11 hsa04012_ErbB_signaling_pathway 27 87 2.592e-32 4.242e-31
12 hsa04910_Insulin_signaling_pathway 31 138 4.068e-32 6.102e-31
13 hsa04662_B_cell_receptor_signaling_pathway 23 75 1.611e-27 2.23e-26
14 hsa04370_VEGF_signaling_pathway 21 76 3.942e-24 5.069e-23
15 hsa04380_Osteoclast_differentiation 24 128 4.902e-23 5.882e-22
16 hsa04620_Toll.like_receptor_signaling_pathway 22 102 1.264e-22 1.422e-21
17 hsa04660_T_cell_receptor_signaling_pathway 22 108 4.861e-22 5.147e-21
18 hsa04664_Fc_epsilon_RI_signaling_pathway 19 79 1.155e-20 1.155e-19
19 hsa04960_Aldosterone.regulated_sodium_reabsorption 15 42 1.705e-19 1.615e-18
20 hsa04640_Hematopoietic_cell_lineage 18 88 2.867e-18 2.58e-17
21 hsa04210_Apoptosis 18 89 3.56e-18 3.051e-17
22 hsa04650_Natural_killer_cell_mediated_cytotoxicity 20 136 3.393e-17 2.776e-16
23 hsa04666_Fc_gamma_R.mediated_phagocytosis 17 95 2.797e-16 2.189e-15
24 hsa04914_Progesterone.mediated_oocyte_maturation 16 87 1.365e-15 1.024e-14
25 hsa04110_Cell_cycle 18 128 3.069e-15 2.209e-14
26 hsa04114_Oocyte_meiosis 16 114 1.148e-13 7.946e-13
27 hsa04115_p53_signaling_pathway 13 69 4.833e-13 3.222e-12
28 hsa04540_Gap_junction 14 90 9.57e-13 6.152e-12
29 hsa04920_Adipocytokine_signaling_pathway 12 68 8.842e-12 5.488e-11
30 hsa04916_Melanogenesis 13 101 7.514e-11 4.508e-10
31 hsa04390_Hippo_signaling_pathway 15 154 1.453e-10 8.436e-10
32 hsa04973_Carbohydrate_digestion_and_absorption 9 44 9.375e-10 5.274e-09
33 hsa04974_Protein_digestion_and_absorption 11 81 1.246e-09 6.795e-09
34 hsa04360_Axon_guidance 13 130 1.825e-09 9.663e-09
35 hsa04350_TGF.beta_signaling_pathway 11 85 2.11e-09 1.085e-08
36 hsa04730_Long.term_depression 10 70 4.319e-09 2.159e-08
37 hsa04145_Phagosome 13 156 1.694e-08 8.24e-08
38 hsa04144_Endocytosis 14 203 5.253e-08 2.488e-07
39 hsa04670_Leukocyte_transendothelial_migration 11 117 6.329e-08 2.921e-07
40 hsa04310_Wnt_signaling_pathway 12 151 1.03e-07 4.634e-07
41 hsa04070_Phosphatidylinositol_signaling_system 9 78 1.75e-07 7.684e-07
42 hsa04320_Dorso.ventral_axis_formation 6 25 2.332e-07 9.86e-07
43 hsa04530_Tight_junction 11 133 2.364e-07 9.86e-07
44 hsa04621_NOD.like_receptor_signaling_pathway 8 59 2.41e-07 9.86e-07
45 hsa04912_GnRH_signaling_pathway 9 101 1.614e-06 6.457e-06
46 hsa03015_mRNA_surveillance_pathway 8 83 3.427e-06 1.341e-05
47 hsa04520_Adherens_junction 7 73 1.47e-05 5.629e-05
48 hsa04962_Vasopressin.regulated_water_reabsorption 5 44 0.0001129 0.0004217
49 hsa04720_Long.term_potentiation 6 70 0.0001148 0.0004217
50 hsa04623_Cytosolic_DNA.sensing_pathway 5 56 0.0003572 0.001286
51 hsa04020_Calcium_signaling_pathway 8 177 0.0007389 0.002608
52 hsa00562_Inositol_phosphate_metabolism 4 57 0.003453 0.01195
53 hsa04514_Cell_adhesion_molecules_.CAMs. 6 136 0.003803 0.01292
54 hsa04622_RIG.I.like_receptor_signaling_pathway 4 71 0.007549 0.02516
55 hsa04270_Vascular_smooth_muscle_contraction 4 116 0.03824 0.1252
56 hsa04140_Regulation_of_autophagy 2 34 0.05282 0.1698
57 hsa04141_Protein_processing_in_endoplasmic_reticulum 4 168 0.1119 0.3534
58 hsa04610_Complement_and_coagulation_cascades 2 69 0.1735 0.5383
59 hsa03320_PPAR_signaling_pathway 2 70 0.1774 0.5411
60 hsa04612_Antigen_processing_and_presentation 2 78 0.2089 0.6268
61 hsa04972_Pancreatic_secretion 2 101 0.3016 0.8482
62 hsa03013_RNA_transport 2 152 0.4951 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

MEG3

 hsa-let-7d-5p;hsa-miR-151a-3p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-577;hsa-miR-616-5p;hsa-miR-629-3p;hsa-miR-7-1-3p 17 THBS1 Sponge network -1.645 0.00049 -1.249 0.00266 0.524
2

PCA3

 hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-18a-3p;hsa-miR-20a-5p;hsa-miR-27a-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-3662;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-616-5p;hsa-miR-944 20 FGF7 Sponge network -2.778 8.0E-5 -1.56 0.00499 0.493
3

PCA3

 hsa-miR-130b-3p;hsa-miR-144-3p;hsa-miR-16-1-3p;hsa-miR-183-5p;hsa-miR-19b-1-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-33a-5p;hsa-miR-590-5p;hsa-miR-944 11 ITGA8 Sponge network -2.778 8.0E-5 -4.038 0 0.488
4

PCA3

 hsa-miR-103a-2-5p;hsa-miR-141-5p;hsa-miR-200b-3p;hsa-miR-20a-3p;hsa-miR-330-3p;hsa-miR-33a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-34c-3p;hsa-miR-452-3p;hsa-miR-576-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p 14 ITGA9 Sponge network -2.778 8.0E-5 -2.67 0 0.483
5

PCA3

 hsa-miR-141-5p;hsa-miR-200c-3p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-335-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-944 10 ITGA1 Sponge network -2.778 8.0E-5 -0.62 0.09036 0.476
6

RFPL1S

 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-17-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-501-3p;hsa-miR-502-3p;hsa-miR-505-3p 11 AKT3 Sponge network -0.223 0.70704 -0.749 0.06936 0.466
7

MEG3

 hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-18a-3p;hsa-miR-20a-5p;hsa-miR-31-5p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-3662;hsa-miR-429;hsa-miR-577;hsa-miR-616-5p;hsa-miR-7-1-3p 16 FGF7 Sponge network -1.645 0.00049 -1.56 0.00499 0.458
8

PCA3

 hsa-miR-1254;hsa-miR-1271-5p;hsa-miR-141-3p;hsa-miR-17-3p;hsa-miR-182-5p;hsa-miR-185-3p;hsa-miR-18a-3p;hsa-miR-18a-5p;hsa-miR-193b-5p;hsa-miR-200a-3p;hsa-miR-22-5p;hsa-miR-224-5p;hsa-miR-23a-3p;hsa-miR-590-3p;hsa-miR-616-5p;hsa-miR-671-5p;hsa-miR-939-5p;hsa-miR-940;hsa-miR-96-5p 19 GNG7 Sponge network -2.778 8.0E-5 -3.457 0 0.457
9

PCA3

 hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-128-3p;hsa-miR-130b-3p;hsa-miR-193b-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-301a-3p;hsa-miR-335-5p;hsa-miR-590-3p;hsa-miR-671-5p 15 KIT Sponge network -2.778 8.0E-5 -3.335 0 0.45
10 CASC2 hsa-miR-183-5p;hsa-miR-193b-3p;hsa-miR-193b-5p;hsa-miR-218-5p;hsa-miR-22-5p;hsa-miR-224-5p;hsa-miR-2355-3p;hsa-miR-24-2-5p;hsa-miR-369-3p;hsa-miR-452-5p;hsa-miR-654-3p;hsa-miR-944 12 PRKCA Sponge network -0.561 0.05962 -0.525 0.15685 0.436
11

PCA3

 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-135b-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-33a-3p;hsa-miR-370-3p;hsa-miR-654-5p;hsa-miR-93-3p;hsa-miR-93-5p;hsa-miR-944 14 COL4A3 Sponge network -2.778 8.0E-5 -3.649 1.0E-5 0.436
12

MEG3

 hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-3662;hsa-miR-577;hsa-miR-592;hsa-miR-629-5p 13 IGF1 Sponge network -1.645 0.00049 -2.083 0.00135 0.434
13

PCA3

 hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-103a-3p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-330-3p;hsa-miR-335-5p;hsa-miR-3662;hsa-miR-3682-3p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-3p 28 FGF2 Sponge network -2.778 8.0E-5 -1.879 0.00013 0.416
14

MEG3

 hsa-miR-103a-3p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-19b-1-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-330-3p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-3662;hsa-miR-429;hsa-miR-577;hsa-miR-93-3p 19 FGF2 Sponge network -1.645 0.00049 -1.879 0.00013 0.415
15

MEG3

 hsa-miR-106b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-330-3p;hsa-miR-335-3p;hsa-miR-577 11 FGFR1 Sponge network -1.645 0.00049 -1.499 0.00051 0.412
16

PCA3

 hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-181a-2-3p;hsa-miR-182-5p;hsa-miR-224-3p;hsa-miR-23a-3p;hsa-miR-299-5p;hsa-miR-301a-3p;hsa-miR-33a-3p;hsa-miR-34c-3p;hsa-miR-576-5p;hsa-miR-629-3p;hsa-miR-944 15 COL4A4 Sponge network -2.778 8.0E-5 -2.066 0.00264 0.409
17

PCA3

 hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-181b-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-27a-3p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-3662;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-629-5p;hsa-miR-940 24 IGF1 Sponge network -2.778 8.0E-5 -2.083 0.00135 0.404
18

EMX2OS

 hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-27a-5p;hsa-miR-34a-5p;hsa-miR-424-5p;hsa-miR-589-3p 10 RELN Sponge network -1.088 0.10042 -4.293 0 0.4
19

DGCR5

 hsa-miR-107;hsa-miR-140-3p;hsa-miR-148a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-326;hsa-miR-338-3p;hsa-miR-362-5p;hsa-miR-501-5p;hsa-miR-577 10 NTRK2 Sponge network 1.383 0.01835 0.129 0.90432 0.38
20

MEG3

 hsa-let-7g-3p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-196a-5p;hsa-miR-196b-5p;hsa-miR-20a-5p;hsa-miR-219a-5p;hsa-miR-335-3p;hsa-miR-93-5p;hsa-miR-96-5p 14 PDGFRA Sponge network -1.645 0.00049 -1.161 0.00469 0.38
21

DGCR5

 hsa-let-7g-5p;hsa-miR-140-3p;hsa-miR-148a-5p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-215-5p;hsa-miR-30d-5p;hsa-miR-362-3p;hsa-miR-375;hsa-miR-500a-3p;hsa-miR-577;hsa-miR-592;hsa-miR-625-5p;hsa-miR-7-5p 16 IGF1R Sponge network 1.383 0.01835 -0.553 0.17433 0.365
22

EMX2OS

 hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-192-5p;hsa-miR-19b-1-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-21-3p;hsa-miR-215-5p;hsa-miR-222-3p;hsa-miR-29a-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-503-5p;hsa-miR-577;hsa-miR-589-3p;hsa-miR-92a-3p;hsa-miR-93-3p 22 FGF2 Sponge network -1.088 0.10042 -1.879 0.00013 0.362
23

EMX2OS

 hsa-miR-107;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-362-3p;hsa-miR-501-3p;hsa-miR-502-3p;hsa-miR-505-3p;hsa-miR-577 12 AKT3 Sponge network -1.088 0.10042 -0.749 0.06936 0.354
24

AGAP11

 hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-146a-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-192-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-335-3p 12 PRKAA2 Sponge network -1.728 0.00016 -3.711 4.0E-5 0.344
25 HAR1A hsa-miR-1254;hsa-miR-141-3p;hsa-miR-17-3p;hsa-miR-182-5p;hsa-miR-185-3p;hsa-miR-18a-3p;hsa-miR-18a-5p;hsa-miR-193b-5p;hsa-miR-224-5p;hsa-miR-671-5p;hsa-miR-940 11 GNG7 Sponge network -0.801 0.17598 -3.457 0 0.341
26

EMX2OS

 hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-18a-3p;hsa-miR-20a-5p;hsa-miR-424-5p;hsa-miR-577;hsa-miR-7-1-3p 10 FGF7 Sponge network -1.088 0.10042 -1.56 0.00499 0.338
27

AGAP11

 hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-181b-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-320b;hsa-miR-3662;hsa-miR-421;hsa-miR-629-5p 14 IGF1 Sponge network -1.728 0.00016 -2.083 0.00135 0.332
28

AGAP11

 hsa-miR-16-1-3p;hsa-miR-18a-5p;hsa-miR-222-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-326;hsa-miR-532-3p;hsa-miR-590-5p;hsa-miR-629-5p 10 FGF1 Sponge network -1.728 0.00016 -0.16 0.73397 0.329
29

EMX2OS

 hsa-miR-1254;hsa-miR-141-3p;hsa-miR-17-3p;hsa-miR-182-5p;hsa-miR-185-3p;hsa-miR-18a-3p;hsa-miR-18a-5p;hsa-miR-200a-3p;hsa-miR-3127-5p;hsa-miR-92a-3p 10 GNG7 Sponge network -1.088 0.10042 -3.457 0 0.327
30

EMX2OS

 hsa-let-7d-5p;hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-192-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-21-3p;hsa-miR-335-3p;hsa-miR-577;hsa-miR-7-1-3p 12 PRKAA2 Sponge network -1.088 0.10042 -3.711 4.0E-5 0.325
31

PCA3

 hsa-let-7a-3p;hsa-let-7b-3p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-181a-2-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-19b-3p;hsa-miR-224-3p;hsa-miR-301a-3p;hsa-miR-3065-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-5p;hsa-miR-96-5p 20 CCND2 Sponge network -2.778 8.0E-5 -0.496 0.3 0.318
32

RFPL1S

 hsa-miR-107;hsa-miR-192-5p;hsa-miR-19b-1-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-215-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-29a-5p;hsa-miR-335-5p;hsa-miR-429 12 FGF2 Sponge network -0.223 0.70704 -1.879 0.00013 0.314
33

MEG3

 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-577;hsa-miR-616-5p 11 AKT3 Sponge network -1.645 0.00049 -0.749 0.06936 0.312
34

PCA3

 hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-let-7g-3p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-149-5p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-196a-5p;hsa-miR-196b-5p;hsa-miR-20a-5p;hsa-miR-219a-5p;hsa-miR-224-5p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-301a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-590-5p;hsa-miR-93-5p;hsa-miR-944;hsa-miR-96-5p 26 PDGFRA Sponge network -2.778 8.0E-5 -1.161 0.00469 0.31
35

PCA3

 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-144-3p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-188-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-330-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-96-5p 28 PIK3R1 Sponge network -2.778 8.0E-5 -1.094 2.0E-5 0.309
36

PCA3

 hsa-let-7a-3p;hsa-let-7d-5p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-33a-3p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-616-5p;hsa-miR-629-3p;hsa-miR-940 19 THBS1 Sponge network -2.778 8.0E-5 -1.249 0.00266 0.302
37

RFPL1S

 hsa-miR-126-5p;hsa-miR-18a-5p;hsa-miR-222-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-330-5p;hsa-miR-429;hsa-miR-532-3p;hsa-miR-550a-5p;hsa-miR-625-5p;hsa-miR-7-5p 12 FGF1 Sponge network -0.223 0.70704 -0.16 0.73397 0.3
38

MEG3

 hsa-let-7d-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-31-5p;hsa-miR-335-3p;hsa-miR-577;hsa-miR-7-1-3p 12 PRKAA2 Sponge network -1.645 0.00049 -3.711 4.0E-5 0.287
39

PCA3

 hsa-miR-107;hsa-miR-128-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p 10 RELN Sponge network -2.778 8.0E-5 -4.293 0 0.286
40

EMX2OS

 hsa-miR-135b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-577 10 FGFR1 Sponge network -1.088 0.10042 -1.499 0.00051 0.281
41

EMX2OS

 hsa-miR-15a-5p;hsa-miR-192-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-196a-5p;hsa-miR-215-5p;hsa-miR-335-3p;hsa-miR-34a-5p;hsa-miR-362-3p;hsa-miR-500a-3p;hsa-miR-577;hsa-miR-592;hsa-miR-625-5p;hsa-miR-7-1-3p;hsa-miR-7-5p;hsa-miR-877-5p 16 IGF1R Sponge network -1.088 0.10042 -0.553 0.17433 0.28
42

PCA3

 hsa-miR-183-5p;hsa-miR-193b-3p;hsa-miR-193b-5p;hsa-miR-200c-3p;hsa-miR-22-5p;hsa-miR-224-5p;hsa-miR-2355-3p;hsa-miR-369-3p;hsa-miR-590-3p;hsa-miR-93-3p;hsa-miR-944 11 PRKCA Sponge network -2.778 8.0E-5 -0.525 0.15685 0.278
43

EMX2OS

 hsa-let-7d-5p;hsa-miR-151a-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-577;hsa-miR-7-1-3p;hsa-miR-92a-3p 13 THBS1 Sponge network -1.088 0.10042 -1.249 0.00266 0.277
44

AGAP11

 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-135b-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-93-3p;hsa-miR-93-5p 10 COL4A3 Sponge network -1.728 0.00016 -3.649 1.0E-5 0.276
45

MEG3

 hsa-let-7d-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-141-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-18a-3p;hsa-miR-197-3p;hsa-miR-1976;hsa-miR-20a-5p;hsa-miR-429;hsa-miR-96-5p 14 CREB3L2 Sponge network -1.645 0.00049 -0.669 0.00222 0.27
46

EMX2OS

 hsa-let-7g-3p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-196a-5p;hsa-miR-196b-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-33b-5p 10 PDGFRA Sponge network -1.088 0.10042 -1.161 0.00469 0.259
47

PCA3

 hsa-miR-130b-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-335-5p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p 10 SOS2 Sponge network -2.778 8.0E-5 -0.553 0.00084 0.258

Quest ID: f9bd743e8198635f539d6a1e1b22d9b5