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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7a-5p ACTB -0.06 0.98501 0.06 0.98376 miRNAWalker2 validate -0.14 0.00551 NA
2 hsa-miR-92a-3p ACTB 0.03 0.99325 0.06 0.98376 miRNAWalker2 validate -0.13 0 NA
3 hsa-miR-221-3p AMOT 0.09 0.95912 0.21 0.86549 miRNAWalker2 validate -0.3 0.00399 NA
4 hsa-miR-330-5p AMOT -0.28 0.81569 0.21 0.86549 miRanda -0.35 0.00132 NA
5 hsa-miR-106b-5p APC -0.3 0.86929 0.2 0.85295 miRNAWalker2 validate; miRTarBase -0.22 0 23087084 miR 106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma; Moreover we demonstrated that miR-106b downregulates APC expression by directly targeting the 3'-untranslated region of APC messenger RNA; Taken together our results suggest that miR-106b plays an important role in promoting the proliferation of human hepatoma cells and presents a novel mechanism of micro RNA-mediated direct suppression of APC expression in cancer cells
6 hsa-miR-148a-3p APC -0.1 0.97698 0.2 0.85295 miRNAWalker2 validate -0.12 0.00641 NA
7 hsa-miR-154-3p APC -0.17 0.5465 0.2 0.85295 TargetScan -0.12 0.00356 NA
8 hsa-miR-192-5p APC -0.12 0.97293 0.2 0.85295 miRNAWalker2 validate -0.11 0.00054 NA
9 hsa-miR-193a-3p APC -0.25 0.65436 0.2 0.85295 miRanda -0.15 0.00011 NA
10 hsa-miR-27a-3p APC -0.12 0.9588 0.2 0.85295 miRNAWalker2 validate; miRTarBase; miRNATAP -0.17 0.00984 22018270 Finally the APC gene was identified as the direct and functional target of miR-27
11 hsa-miR-335-3p APC -0.24 0.8845 0.2 0.85295 mirMAP -0.21 0 NA
12 hsa-miR-374a-5p APC -0.34 0.76692 0.2 0.85295 mirMAP -0.28 0 NA
13 hsa-miR-374b-5p APC -0.29 0.8357 0.2 0.85295 mirMAP -0.2 0.00044 NA
14 hsa-miR-421 APC -0.18 0.7347 0.2 0.85295 miRanda -0.15 0.0002 NA
15 hsa-miR-450b-5p APC -0.01 0.98315 0.2 0.85295 miRNATAP -0.17 6.0E-5 NA
16 hsa-miR-501-3p APC -0.75 0.55276 0.2 0.85295 TargetScan -0.12 0.00171 NA
17 hsa-miR-590-3p APC -0.28 0.59127 0.2 0.85295 PITA; miRanda; mirMAP; miRNATAP -0.1 0.00339 NA
18 hsa-miR-20a-3p APC2 0.46 0.57674 -0.38 0.36375 mirMAP -0.17 0.00956 NA
19 hsa-miR-452-3p APC2 -0.17 0.79901 -0.38 0.36375 mirMAP -0.17 0.00953 NA
20 hsa-miR-582-5p AXIN2 -0.4 0.58123 0.16 0.92249 miRNATAP -0.54 0 NA
21 hsa-miR-126-5p BIRC2 0.08 0.95664 -0.01 0.9934 mirMAP -0.12 0.00073 NA
22 hsa-miR-218-5p BIRC5 0.23 0.81021 -0.18 0.87664 miRTarBase; MirTarget -0.22 2.0E-5 25473903; 25900794; 26442524 Survivin BIRC5 was subsequently identified as an important cervical cancer target of miR-218 using in silico prediction mRNA profiling and quantitative real-time PCR qRT-PCR;miR-218 binds survivin BIRC5 mRNA 3'-UTR and down-regulated reporter luciferase activity;MiR-218 promoted apoptosis inhibited cell proliferation and caused cell cycle arrest in CRC cells by suppressing BIRC5 expression; In conclusion we demonstrated that high miR-218 expression had a positive prognostic value in 5-FU-based treatments for CRC patients and discovered a novel mechanism mediated by miR-218 to promote apoptosis and to function synergistically with 5-FU to promote chemosensitivity by suppressing BIRC5 and TS in CRC
23 hsa-miR-34c-5p BIRC5 -0.02 0.95279 -0.18 0.87664 miRanda -0.15 0.00468 NA
24 hsa-miR-106a-5p BMP2 -0.2 0.80221 -0.46 0.61561 miRNATAP -0.33 0.00015 NA
25 hsa-miR-17-5p BMP2 -0.18 0.93454 -0.46 0.61561 TargetScan -0.34 1.0E-5 NA
26 hsa-miR-20a-5p BMP2 -0.18 0.92812 -0.46 0.61561 miRNATAP -0.3 9.0E-5 NA
27 hsa-miR-335-3p BMP2 -0.24 0.8845 -0.46 0.61561 mirMAP -0.37 0 NA
28 hsa-miR-335-5p BMP2 -0.03 0.97338 -0.46 0.61561 miRNAWalker2 validate -0.34 3.0E-5 NA
29 hsa-miR-935 BMP5 0.05 0.93942 -0.44 0.59172 miRNATAP -0.24 0.00442 NA
30 hsa-miR-1275 BMP6 -0.83 0.08038 0.34 0.37045 MirTarget -0.2 1.0E-5 NA
31 hsa-miR-130b-3p BMP6 -0.22 0.82466 0.34 0.37045 MirTarget -0.42 0 NA
32 hsa-miR-301a-3p BMP6 -0.11 0.83169 0.34 0.37045 MirTarget -0.26 6.0E-5 NA
33 hsa-miR-362-3p BMP6 -0.72 0.03459 0.34 0.37045 miRanda -0.21 0.00048 NA
34 hsa-miR-454-3p BMP6 -0.1 0.84355 0.34 0.37045 MirTarget -0.32 0.00028 NA
35 hsa-miR-590-3p BMP6 -0.28 0.59127 0.34 0.37045 mirMAP -0.25 6.0E-5 NA
36 hsa-miR-590-5p BMP6 -0.55 0.47274 0.34 0.37045 miRanda -0.33 0 NA
37 hsa-miR-194-3p BMP8A -0.61 0.73321 0.12 0.88565 MirTarget -0.17 0.0005 NA
38 hsa-miR-30b-3p BMP8A -0.51 0.16242 0.12 0.88565 MirTarget -0.19 0.00098 NA
39 hsa-miR-30d-3p BMP8A -0.12 0.81491 0.12 0.88565 MirTarget -0.29 1.0E-5 NA
40 hsa-miR-30e-3p BMP8A -0.22 0.93866 0.12 0.88565 MirTarget -0.35 0.00149 NA
41 hsa-miR-423-5p BMP8A -0.14 0.91245 0.12 0.88565 MirTarget -0.27 0.00022 NA
42 hsa-miR-142-5p BMPR1A -0.12 0.92967 -0.08 0.94026 MirTarget -0.1 3.0E-5 NA
43 hsa-miR-589-5p BMPR1A -0.45 0.72273 -0.08 0.94026 MirTarget -0.14 0.00026 NA
44 hsa-let-7a-3p BMPR1B -0.22 0.85543 0.03 0.96601 miRNATAP -0.61 0.00028 NA
45 hsa-miR-1227-3p BMPR1B -0.54 0.10764 0.03 0.96601 MirTarget -0.45 0.00017 NA
46 hsa-miR-130b-3p BMPR1B -0.22 0.82466 0.03 0.96601 miRNATAP -1.05 0 NA
47 hsa-miR-144-3p BMPR1B 0.05 0.93587 0.03 0.96601 MirTarget; miRNATAP -0.51 0 NA
48 hsa-miR-16-2-3p BMPR1B -0.37 0.54685 0.03 0.96601 mirMAP -0.9 0 NA
49 hsa-miR-182-5p BMPR1B -0.1 0.97338 0.03 0.96601 MirTarget -0.44 0.0011 NA
50 hsa-miR-23a-3p BMPR1B -0.12 0.96272 0.03 0.96601 mirMAP -0.83 0.00323 NA
51 hsa-miR-26b-5p BMPR1B -0.02 0.99038 0.03 0.96601 mirMAP -0.84 3.0E-5 NA
52 hsa-miR-29a-5p BMPR1B -0.32 0.60044 0.03 0.96601 MirTarget; mirMAP; miRNATAP -1.01 0 NA
53 hsa-miR-301a-3p BMPR1B -0.11 0.83169 0.03 0.96601 miRNATAP -0.52 7.0E-5 NA
54 hsa-miR-331-3p BMPR1B -0.4 0.67059 0.03 0.96601 miRNATAP -0.62 0.00014 NA
55 hsa-miR-339-5p BMPR1B -0.3 0.71291 0.03 0.96601 miRanda -0.54 1.0E-5 NA
56 hsa-miR-362-3p BMPR1B -0.72 0.03459 0.03 0.96601 MirTarget; miRanda -0.58 0 NA
57 hsa-miR-374a-5p BMPR1B -0.34 0.76692 0.03 0.96601 MirTarget -1.09 0 NA
58 hsa-miR-374b-5p BMPR1B -0.29 0.8357 0.03 0.96601 MirTarget -0.97 0 NA
59 hsa-miR-421 BMPR1B -0.18 0.7347 0.03 0.96601 miRanda -0.8 0 NA
60 hsa-miR-429 BMPR1B -0.46 0.80624 0.03 0.96601 miRNATAP -0.7 0 NA
61 hsa-miR-501-5p BMPR1B -0.83 0.05827 0.03 0.96601 mirMAP -0.55 0 NA
62 hsa-miR-548o-3p BMPR1B -0.19 0.51773 0.03 0.96601 mirMAP -0.63 0 NA
63 hsa-miR-576-5p BMPR1B -0.51 0.41719 0.03 0.96601 mirMAP -1.03 0 NA
64 hsa-miR-590-3p BMPR1B -0.28 0.59127 0.03 0.96601 miRanda; mirMAP -0.86 0 NA
65 hsa-miR-629-3p BMPR1B -0.5 0.33397 0.03 0.96601 MirTarget -0.65 0 NA
66 hsa-miR-7-1-3p BMPR1B -0.46 0.6659 0.03 0.96601 MirTarget -0.83 0 NA
67 hsa-let-7a-3p BMPR2 -0.22 0.85543 0.18 0.9 MirTarget; miRNATAP -0.18 0.00013 NA
68 hsa-let-7f-1-3p BMPR2 -0.31 0.69341 0.18 0.9 MirTarget -0.26 2.0E-5 NA
69 hsa-let-7f-2-3p BMPR2 -0.05 0.88212 0.18 0.9 MirTarget -0.11 0.00157 NA
70 hsa-miR-106a-5p BMPR2 -0.2 0.80221 0.18 0.9 MirTarget; miRNATAP -0.23 0 NA
71 hsa-miR-106b-5p BMPR2 -0.3 0.86929 0.18 0.9 MirTarget; miRNATAP -0.3 0 NA
72 hsa-miR-126-5p BMPR2 0.08 0.95664 0.18 0.9 mirMAP -0.23 2.0E-5 NA
73 hsa-miR-128-3p BMPR2 -0.44 0.78389 0.18 0.9 miRNAWalker2 validate -0.37 0 NA
74 hsa-miR-130b-3p BMPR2 -0.22 0.82466 0.18 0.9 MirTarget; miRNATAP -0.28 0 NA
75 hsa-miR-136-5p BMPR2 -0.03 0.96513 0.18 0.9 miRNATAP -0.12 0.00193 NA
76 hsa-miR-142-5p BMPR2 -0.12 0.92967 0.18 0.9 MirTarget; PITA -0.16 1.0E-5 NA
77 hsa-miR-148a-3p BMPR2 -0.1 0.97698 0.18 0.9 mirMAP -0.15 0.00044 NA
78 hsa-miR-148a-5p BMPR2 -0.45 0.74842 0.18 0.9 mirMAP -0.21 0 NA
79 hsa-miR-148b-3p BMPR2 -0.2 0.91188 0.18 0.9 mirMAP -0.22 0.00026 NA
80 hsa-miR-16-2-3p BMPR2 -0.37 0.54685 0.18 0.9 mirMAP -0.24 0 NA
81 hsa-miR-17-5p BMPR2 -0.18 0.93454 0.18 0.9 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.22 0 NA
82 hsa-miR-185-5p BMPR2 -0.29 0.82059 0.18 0.9 MirTarget -0.41 0 NA
83 hsa-miR-186-5p BMPR2 -0.32 0.85413 0.18 0.9 mirMAP -0.31 0 NA
84 hsa-miR-192-3p BMPR2 -0.18 0.91024 0.18 0.9 MirTarget -0.14 0.00011 NA
85 hsa-miR-192-5p BMPR2 -0.12 0.97293 0.18 0.9 miRNAWalker2 validate -0.2 0 NA
86 hsa-miR-19a-3p BMPR2 -0.21 0.84464 0.18 0.9 miRNAWalker2 validate; MirTarget; miRNATAP -0.2 0 NA
87 hsa-miR-19b-3p BMPR2 -0.03 0.98666 0.18 0.9 miRNAWalker2 validate; MirTarget; miRNATAP -0.15 0.00022 NA
88 hsa-miR-200b-3p BMPR2 -0.43 0.86396 0.18 0.9 mirMAP -0.16 0.00012 NA
89 hsa-miR-200b-5p BMPR2 -0.5 0.72226 0.18 0.9 mirMAP -0.2 0 NA
90 hsa-miR-200c-3p BMPR2 -0.44 0.88712 0.18 0.9 mirMAP -0.14 0.00054 NA
91 hsa-miR-20a-5p BMPR2 -0.18 0.92812 0.18 0.9 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.19 0 NA
92 hsa-miR-21-5p BMPR2 -0.15 0.97024 0.18 0.9 miRNAWalker2 validate; miRTarBase; MirTarget -0.27 0.00014 NA
93 hsa-miR-215-5p BMPR2 -0.14 0.94481 0.18 0.9 miRNAWalker2 validate -0.1 0 NA
94 hsa-miR-25-3p BMPR2 -0.46 0.87857 0.18 0.9 miRNATAP -0.3 0 NA
95 hsa-miR-26a-1-3p BMPR2 -0.43 0.18214 0.18 0.9 mirMAP -0.17 0 NA
96 hsa-miR-26a-2-3p BMPR2 -0.43 0.28777 0.18 0.9 mirMAP -0.19 0 NA
97 hsa-miR-26b-5p BMPR2 -0.02 0.99038 0.18 0.9 miRNAWalker2 validate -0.18 0.00108 NA
98 hsa-miR-29a-5p BMPR2 -0.32 0.60044 0.18 0.9 mirMAP -0.26 0 NA
99 hsa-miR-301a-3p BMPR2 -0.11 0.83169 0.18 0.9 MirTarget; miRNATAP -0.15 5.0E-5 NA
100 hsa-miR-30e-5p BMPR2 -0.07 0.97968 0.18 0.9 mirMAP -0.17 0.00988 NA
101 hsa-miR-32-3p BMPR2 -0.57 0.13133 0.18 0.9 mirMAP -0.19 0 NA
102 hsa-miR-32-5p BMPR2 -0.06 0.95298 0.18 0.9 miRNATAP -0.18 1.0E-5 NA
103 hsa-miR-335-3p BMPR2 -0.24 0.8845 0.18 0.9 mirMAP -0.13 0.00052 NA
104 hsa-miR-33a-3p BMPR2 -0.79 0.01052 0.18 0.9 mirMAP -0.17 0 NA
105 hsa-miR-33a-5p BMPR2 -0.21 0.85331 0.18 0.9 mirMAP -0.13 0 NA
106 hsa-miR-33b-5p BMPR2 -0.16 0.73744 0.18 0.9 mirMAP -0.16 0 NA
107 hsa-miR-362-3p BMPR2 -0.72 0.03459 0.18 0.9 MirTarget; PITA; miRanda; miRNATAP -0.15 1.0E-5 NA
108 hsa-miR-369-3p BMPR2 0.12 0.8323 0.18 0.9 MirTarget; PITA; miRNATAP -0.16 0.00016 NA
109 hsa-miR-375 BMPR2 -0.69 0.83172 0.18 0.9 miRNATAP -0.11 3.0E-5 NA
110 hsa-miR-378a-5p BMPR2 -0.56 0.72488 0.18 0.9 MirTarget -0.25 0 NA
111 hsa-miR-429 BMPR2 -0.46 0.80624 0.18 0.9 mirMAP; miRNATAP -0.16 0 NA
112 hsa-miR-450b-5p BMPR2 -0.01 0.98315 0.18 0.9 MirTarget; mirMAP -0.15 0.00056 NA
113 hsa-miR-454-3p BMPR2 -0.1 0.84355 0.18 0.9 MirTarget; miRNATAP -0.16 0.00162 NA
114 hsa-miR-455-5p BMPR2 -0.14 0.86574 0.18 0.9 PITA -0.15 0.00023 NA
115 hsa-miR-491-3p BMPR2 -0.51 0.13784 0.18 0.9 mirMAP -0.1 0.00323 NA
116 hsa-miR-532-5p BMPR2 -0.35 0.87895 0.18 0.9 PITA -0.15 0.00021 NA
117 hsa-miR-577 BMPR2 -1.06 0.32606 0.18 0.9 MirTarget; miRNATAP -0.14 0 NA
118 hsa-miR-582-3p BMPR2 -0.23 0.89768 0.18 0.9 PITA; miRNATAP -0.26 0 NA
119 hsa-miR-582-5p BMPR2 -0.4 0.58123 0.18 0.9 mirMAP -0.26 0 NA
120 hsa-miR-584-5p BMPR2 -0.22 0.90686 0.18 0.9 mirMAP -0.1 0.00018 NA
121 hsa-miR-590-3p BMPR2 -0.28 0.59127 0.18 0.9 MirTarget; miRanda; mirMAP; miRNATAP -0.24 0 NA
122 hsa-miR-590-5p BMPR2 -0.55 0.47274 0.18 0.9 MirTarget; PITA; miRNATAP -0.29 0 NA
123 hsa-miR-625-3p BMPR2 -0.98 0.62433 0.18 0.9 mirMAP -0.22 0 NA
124 hsa-miR-629-5p BMPR2 -0.39 0.79854 0.18 0.9 mirMAP -0.22 0 NA
125 hsa-miR-651-5p BMPR2 -0.57 0.17254 0.18 0.9 MirTarget -0.15 0 NA
126 hsa-miR-671-5p BMPR2 -0.37 0.41121 0.18 0.9 miRNATAP -0.23 0 NA
127 hsa-miR-7-1-3p BMPR2 -0.46 0.6659 0.18 0.9 mirMAP -0.22 0 NA
128 hsa-miR-7-5p BMPR2 0.21 0.77371 0.18 0.9 miRNAWalker2 validate; miRNATAP -0.14 0 NA
129 hsa-miR-769-5p BMPR2 -0.31 0.7357 0.18 0.9 miRNATAP -0.27 0 NA
130 hsa-miR-877-5p BMPR2 -0.32 0.43595 0.18 0.9 MirTarget -0.19 0 NA
131 hsa-miR-92a-3p BMPR2 0.03 0.99325 0.18 0.9 miRNAWalker2 validate; miRNATAP -0.13 0.00286 NA
132 hsa-miR-92b-3p BMPR2 -0.57 0.68932 0.18 0.9 miRNATAP -0.26 0 NA
133 hsa-miR-93-3p BMPR2 -0.44 0.5499 0.18 0.9 miRNAWalker2 validate -0.24 0 NA
134 hsa-miR-93-5p BMPR2 -0.61 0.8253 0.18 0.9 miRNAWalker2 validate; MirTarget; miRNATAP -0.29 0 NA
135 hsa-miR-96-5p BMPR2 0.09 0.92309 0.18 0.9 mirMAP -0.11 0.00186 NA
136 hsa-miR-16-5p CCND1 0.01 0.99448 -0.25 0.89067 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.13 0.00823 23991964; 22922827; 18483394 At the molecular level our results further revealed that cyclin D1 expression was negatively regulated by miR-16;CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL
137 hsa-miR-195-5p CCND1 0.34 0.74962 -0.25 0.89067 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.14 0.00272 21350001; 26631043; 25823925 Raf-1 and Ccnd1 were identified as novel direct targets of miR-195 and miR-497 miR-195/497 expression levels in clinical specimens were found to be correlated inversely with malignancy of breast cancer;MiR 195 inhibits the proliferation of human cervical cancer cells by directly targeting cyclin D1; The present study was to evaluate the level of miR-195 and cyclin D1 in CC tissues and cells; We further investigated the molecular mechanisms of miR-195 and cyclin D1 in CC cell lines HeLa and SiHa; Furthermore the expression of miR-195 was inversely proportional to that of cyclin D1 mRNA or protein p = 0.013 p = 0.015 respectively; However the inhibitor of miR-195 promoted the expression of cyclin D1 and cell proliferation; In conclusion our data suggest that miR-195 may have the potential role in treatment of CC patients as well as miR-195 is a novel regulator of invasiveness and tumorigenicity in CC cells by targeting cyclin D1;MicroRNA profiling identifies MiR 195 suppresses osteosarcoma cell metastasis by targeting CCND1; Meanwhile CCND1 was identified as the target gene of miR-195 and further studied; More importantly using real-time PCR we evaluated the expression of miR-195 and CCND1 in osteosarcoma samples from 107 frozen biopsy tissues and 99 formalin- or paraformalin-fixed paraffin-embedded FFPE tissues; Results indicated lowly expressed miR-195 or highly CCND1 correlated with positive overall survival and their expression inversely related to each other; In summary our study suggests miR-195 functions as a tumor metastasis suppressor gene by down-regulating CCND1 and can be used as a potential target in the treatment of osteosarcoma
138 hsa-miR-29c-3p CCND1 0.16 0.94272 -0.25 0.89067 mirMAP -0.14 0.00181 NA
139 hsa-miR-146b-5p CDH1 -0.4 0.83751 -0.12 0.95542 miRanda -0.2 0 NA
140 hsa-miR-22-3p CDH1 0.06 0.98656 -0.12 0.95542 MirTarget -0.2 0.00306 NA
141 hsa-miR-342-3p CDH1 -0.37 0.77314 -0.12 0.95542 miRanda -0.15 6.0E-5 NA
142 hsa-let-7b-5p CRB2 -0.23 0.93895 0.58 0.31517 miRNATAP -0.62 0.00019 NA
143 hsa-miR-342-3p CRB2 -0.37 0.77314 0.58 0.31517 miRNAWalker2 validate; miRanda -0.35 0.00348 NA
144 hsa-miR-1304-5p CTGF -0.5 0.16308 0.32 0.8416 MirTarget -0.23 8.0E-5 NA
145 hsa-miR-16-2-3p CTGF -0.37 0.54685 0.32 0.8416 MirTarget -0.43 0 NA
146 hsa-miR-18a-5p CTGF -0.5 0.61264 0.32 0.8416 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.34 0 23249750 Targeting of TGFβ signature and its essential component CTGF by miR 18 correlates with improved survival in glioblastoma; Indeed microRNA-18a but not other miR-17∼92 members has a functional site in the CTGF 3' UTR and its forced reexpression sharply reduces CTGF protein and mRNA levels; The unexpected effects of miR-18a on CTGF transcription are mediated in part by direct targeting of Smad3 and ensuing weakening of TGFβ signaling
147 hsa-miR-18b-5p CTGF -0.05 0.89998 0.32 0.8416 MirTarget -0.23 5.0E-5 23249750 Targeting of TGFβ signature and its essential component CTGF by miR 18 correlates with improved survival in glioblastoma
148 hsa-miR-19a-3p CTGF -0.21 0.84464 0.32 0.8416 MirTarget; miRNATAP -0.43 0 NA
149 hsa-miR-19b-3p CTGF -0.03 0.98666 0.32 0.8416 MirTarget; miRNATAP -0.52 0 NA
150 hsa-miR-26b-3p CTGF -0.36 0.68112 0.32 0.8416 MirTarget; miRNATAP -0.42 0 25761878 Luciferase reporter assay confirmed the interaction of miR-26b with the 3' untranslated regions UTRs of CTGF and Smad1

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 CANONICAL WNT SIGNALING PATHWAY 26 95 1.486e-39 6.914e-36
2 TISSUE DEVELOPMENT 55 1518 1.127e-36 2.621e-33
3 ORGAN MORPHOGENESIS 45 841 2.607e-36 4.043e-33
4 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 56 1672 1.158e-35 1.347e-32
5 EPITHELIUM DEVELOPMENT 46 945 2.261e-35 2.104e-32
6 WNT SIGNALING PATHWAY 33 351 5.394e-34 4.183e-31
7 REGULATION OF WNT SIGNALING PATHWAY 30 310 3.424e-31 2.276e-28
8 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 43 1021 3.372e-30 1.961e-27
9 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 27 236 4.997e-30 2.569e-27
10 REGULATION OF CELL DIFFERENTIATION 49 1492 5.521e-30 2.569e-27
11 REGULATION OF PROTEIN MODIFICATION PROCESS 51 1710 1.975e-29 8.353e-27
12 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 44 1142 2.311e-29 8.96e-27
13 REGULATION OF PHOSPHORUS METABOLIC PROCESS 49 1618 2.281e-28 8.165e-26
14 POSITIVE REGULATION OF RESPONSE TO STIMULUS 52 1929 5.309e-28 1.647e-25
15 TISSUE MORPHOGENESIS 33 533 5.092e-28 1.647e-25
16 NEUROGENESIS 46 1402 7.569e-28 2.201e-25
17 POSITIVE REGULATION OF CELL DIFFERENTIATION 37 823 1.267e-26 3.275e-24
18 REGULATION OF CELL PROLIFERATION 46 1496 1.226e-26 3.275e-24
19 NEGATIVE REGULATION OF CELL COMMUNICATION 42 1192 2.443e-26 5.983e-24
20 REGULATION OF STEM CELL DIFFERENTIATION 20 113 2.863e-26 6.66e-24
21 TUBE DEVELOPMENT 32 552 3.043e-26 6.743e-24
22 POSITIVE REGULATION OF CELL COMMUNICATION 46 1532 3.385e-26 7.159e-24
23 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 22 162 3.57e-26 7.222e-24
24 POSITIVE REGULATION OF GENE EXPRESSION 48 1733 5.756e-26 1.116e-23
25 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 23 197 8.745e-26 1.628e-23
26 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 17 67 2.381e-25 4.26e-23
27 EMBRYONIC MORPHOGENESIS 31 539 2.726e-25 4.698e-23
28 REGULATION OF ORGAN MORPHOGENESIS 24 242 3.695e-25 6.141e-23
29 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 44 1492 1.399e-24 2.245e-22
30 RESPONSE TO GROWTH FACTOR 29 475 2.38e-24 3.691e-22
31 CELL FATE COMMITMENT 23 227 2.46e-24 3.693e-22
32 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 42 1360 4.242e-24 6.168e-22
33 HIPPO SIGNALING 13 27 5.853e-24 8.253e-22
34 REGULATION OF CARTILAGE DEVELOPMENT 16 63 6.525e-24 8.93e-22
35 SENSORY ORGAN DEVELOPMENT 29 493 6.811e-24 9.054e-22
36 REGULATION OF CELL DEATH 43 1472 8.719e-24 1.127e-21
37 CARDIOVASCULAR SYSTEM DEVELOPMENT 34 788 9.265e-24 1.134e-21
38 CIRCULATORY SYSTEM DEVELOPMENT 34 788 9.265e-24 1.134e-21
39 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 47 1848 9.641e-24 1.137e-21
40 REGULATION OF CELLULAR PROTEIN LOCALIZATION 30 552 9.776e-24 1.137e-21
41 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 15 50 1.034e-23 1.173e-21
42 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 46 1805 3.429e-23 3.799e-21
43 EMBRYO DEVELOPMENT 35 894 4.217e-23 4.563e-21
44 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 38 1135 8.205e-23 8.676e-21
45 MORPHOGENESIS OF AN EPITHELIUM 26 400 1.706e-22 1.764e-20
46 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 29 554 1.8e-22 1.821e-20
47 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 33 801 2.119e-22 2.098e-20
48 EMBRYONIC ORGAN DEVELOPMENT 26 406 2.492e-22 2.416e-20
49 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 13 34 2.636e-22 2.503e-20
50 REGULATION OF CELL DEVELOPMENT 33 836 7.999e-22 7.444e-20
51 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 35 1036 5.184e-21 4.639e-19
52 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 35 1036 5.184e-21 4.639e-19
53 TUBE MORPHOGENESIS 23 323 8.293e-21 7.281e-19
54 CARTILAGE DEVELOPMENT 18 147 1.131e-20 9.566e-19
55 POSITIVE REGULATION OF CELL DEVELOPMENT 26 472 1.12e-20 9.566e-19
56 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 39 1395 1.159e-20 9.629e-19
57 CELL DEVELOPMENT 39 1426 2.519e-20 2.057e-18
58 NEURON DIFFERENTIATION 32 874 3.705e-20 2.972e-18
59 CONNECTIVE TISSUE DEVELOPMENT 19 194 6.706e-20 5.289e-18
60 SKELETAL SYSTEM DEVELOPMENT 25 455 7.416e-20 5.751e-18
61 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 19 207 2.325e-19 1.774e-17
62 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 33 1008 2.475e-19 1.857e-17
63 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 32 957 5.428e-19 4.009e-17
64 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 13 60 1.327e-18 9.648e-17
65 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 34 1152 1.497e-18 1.072e-16
66 NEGATIVE REGULATION OF CELL PROLIFERATION 27 643 1.915e-18 1.35e-16
67 RESPIRATORY SYSTEM DEVELOPMENT 18 197 2.424e-18 1.683e-16
68 RESPONSE TO ENDOGENOUS STIMULUS 37 1450 3.405e-18 2.33e-16
69 REGULATION OF MAPK CASCADE 27 660 3.708e-18 2.501e-16
70 REGULATION OF PROTEIN LOCALIZATION 31 950 4.47e-18 2.929e-16
71 POSITIVE REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 12 48 4.439e-18 2.929e-16
72 REGULATION OF EPITHELIAL CELL PROLIFERATION 20 285 5e-18 3.232e-16
73 POSITIVE REGULATION OF CELL DEATH 26 605 5.257e-18 3.351e-16
74 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 31 983 1.175e-17 7.388e-16
75 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 24 513 1.818e-17 1.128e-15
76 GROWTH 22 410 2.74e-17 1.677e-15
77 MESENCHYME DEVELOPMENT 17 190 3.279e-17 1.956e-15
78 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 17 190 3.279e-17 1.956e-15
79 EPITHELIAL TO MESENCHYMAL TRANSITION 12 56 3.449e-17 2.031e-15
80 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 14 100 4.062e-17 2.362e-15
81 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 39 1784 5.933e-17 3.408e-15
82 EMBRYONIC ORGAN MORPHOGENESIS 19 279 6.479e-17 3.676e-15
83 EYE DEVELOPMENT 20 326 6.905e-17 3.871e-15
84 POSITIVE REGULATION OF CELL PROLIFERATION 28 814 7.025e-17 3.892e-15
85 MESENCHYMAL CELL DIFFERENTIATION 15 134 9.113e-17 4.988e-15
86 REGULATION OF CELL MORPHOGENESIS 24 552 9.558e-17 5.172e-15
87 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 20 337 1.314e-16 7.025e-15
88 NON CANONICAL WNT SIGNALING PATHWAY 15 140 1.781e-16 9.419e-15
89 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 30 1004 1.958e-16 1.024e-14
90 HEART MORPHOGENESIS 17 212 2.103e-16 1.087e-14
91 UROGENITAL SYSTEM DEVELOPMENT 19 299 2.34e-16 1.196e-14
92 HEAD DEVELOPMENT 26 709 2.455e-16 1.242e-14
93 REGULATION OF OSSIFICATION 16 178 2.792e-16 1.397e-14
94 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 17 220 3.925e-16 1.943e-14
95 HEART DEVELOPMENT 22 466 4.014e-16 1.966e-14
96 CELL JUNCTION ORGANIZATION 16 185 5.178e-16 2.51e-14
97 PATTERN SPECIFICATION PROCESS 21 418 5.961e-16 2.859e-14
98 CELL PROLIFERATION 25 672 7.4e-16 3.514e-14
99 STEM CELL DIFFERENTIATION 16 190 7.926e-16 3.725e-14
100 NEGATIVE REGULATION OF CELL DIFFERENTIATION 24 609 8.664e-16 4.031e-14
101 REGULATION OF INTRACELLULAR TRANSPORT 24 621 1.338e-15 6.164e-14
102 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 16 197 1.41e-15 6.432e-14
103 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 15 162 1.631e-15 7.366e-14
104 REGULATION OF KINASE ACTIVITY 26 776 2.117e-15 9.473e-14
105 REGULATION OF CELLULAR LOCALIZATION 32 1277 2.219e-15 9.831e-14
106 GLAND DEVELOPMENT 20 395 2.77e-15 1.216e-13
107 REGULATION OF TRANSFERASE ACTIVITY 28 946 3.212e-15 1.397e-13
108 NEGATIVE REGULATION OF GENE EXPRESSION 34 1493 3.782e-15 1.629e-13
109 REPRODUCTIVE SYSTEM DEVELOPMENT 20 408 5.126e-15 2.188e-13
110 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 14 141 5.674e-15 2.4e-13
111 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 21 470 6.125e-15 2.568e-13
112 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 19 360 7.025e-15 2.893e-13
113 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 16 218 7.002e-15 2.893e-13
114 PALATE DEVELOPMENT 12 85 7.259e-15 2.963e-13
115 CELLULAR COMPONENT MORPHOGENESIS 27 900 8.119e-15 3.285e-13
116 REGULATION OF EMBRYONIC DEVELOPMENT 13 114 9.031e-15 3.622e-13
117 REGULATION OF PROTEIN IMPORT 15 183 1.013e-14 4.03e-13
118 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 35 1656 1.221e-14 4.815e-13
119 REGULATION OF CHONDROCYTE DIFFERENTIATION 10 46 1.418e-14 5.545e-13
120 EPITHELIAL CELL DIFFERENTIATION 21 495 1.699e-14 6.587e-13
121 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 14 154 1.966e-14 7.56e-13
122 GASTRULATION 14 155 2.153e-14 8.21e-13
123 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 33 1517 4.087e-14 1.546e-12
124 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 13 131 5.666e-14 2.126e-12
125 MORPHOGENESIS OF A BRANCHING STRUCTURE 14 167 6.105e-14 2.273e-12
126 BETA CATENIN DESTRUCTION COMPLEX DISASSEMBLY 8 22 6.33e-14 2.328e-12
127 OSSIFICATION 16 251 6.355e-14 2.328e-12
128 POSITIVE REGULATION OF MAPK CASCADE 20 470 7.357e-14 2.674e-12
129 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 22 602 7.693e-14 2.775e-12
130 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 7 13 7.875e-14 2.819e-12
131 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 13 135 8.405e-14 2.985e-12
132 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 28 1087 1.02e-13 3.594e-12
133 REGULATION OF APOPTOTIC SIGNALING PATHWAY 18 363 1.133e-13 3.965e-12
134 POSITIVE REGULATION OF KINASE ACTIVITY 20 482 1.177e-13 4.088e-12
135 SMAD PROTEIN SIGNAL TRANSDUCTION 10 56 1.191e-13 4.106e-12
136 IN UTERO EMBRYONIC DEVELOPMENT 17 311 1.209e-13 4.107e-12
137 REGIONALIZATION 17 311 1.209e-13 4.107e-12
138 MESENCHYME MORPHOGENESIS 9 38 1.339e-13 4.515e-12
139 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 9 39 1.734e-13 5.805e-12
140 REGULATION OF OSTEOBLAST DIFFERENTIATION 12 112 2.194e-13 7.291e-12
141 POSITIVE REGULATION OF OSSIFICATION 11 84 2.407e-13 7.942e-12
142 CHONDROCYTE DIFFERENTIATION 10 60 2.483e-13 8.136e-12
143 NEGATIVE REGULATION OF CELL DEATH 25 872 2.731e-13 8.823e-12
144 CENTRAL NERVOUS SYSTEM DEVELOPMENT 25 872 2.731e-13 8.823e-12
145 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 20 514 3.88e-13 1.245e-11
146 REGULATION OF STEM CELL PROLIFERATION 11 88 4.083e-13 1.301e-11
147 REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 7 16 5.189e-13 1.643e-11
148 CELLULAR RESPONSE TO RETINOIC ACID 10 65 5.781e-13 1.817e-11
149 LENS DEVELOPMENT IN CAMERA TYPE EYE 10 66 6.787e-13 2.119e-11
150 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 23 750 7.399e-13 2.295e-11
151 SKELETAL SYSTEM MORPHOGENESIS 14 201 7.9e-13 2.434e-11
152 VASCULATURE DEVELOPMENT 19 469 7.987e-13 2.445e-11
153 RESPONSE TO BMP 11 94 8.603e-13 2.599e-11
154 CELLULAR RESPONSE TO BMP STIMULUS 11 94 8.603e-13 2.599e-11
155 ESTABLISHMENT OR MAINTENANCE OF EPITHELIAL CELL APICAL BASAL POLARITY 8 30 1.123e-12 3.371e-11
156 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 21 616 1.172e-12 3.497e-11
157 REGULATION OF PROTEIN TARGETING 16 307 1.41e-12 4.179e-11
158 PROTEIN PHOSPHORYLATION 25 944 1.578e-12 4.646e-11
159 RESPONSE TO LIPID 24 888 3.154e-12 9.231e-11
160 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 17 381 3.18e-12 9.247e-11
161 RESPONSE TO RETINOIC ACID 11 107 3.669e-12 1.061e-10
162 INTRACELLULAR SIGNAL TRANSDUCTION 31 1572 4.106e-12 1.179e-10
163 POSITIVE REGULATION OF MOLECULAR FUNCTION 33 1791 4.174e-12 1.191e-10
164 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 12 144 4.543e-12 1.289e-10
165 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 14 229 4.664e-12 1.315e-10
166 DEVELOPMENTAL GROWTH 16 333 4.84e-12 1.357e-10
167 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY 11 110 4.99e-12 1.39e-10
168 RESPONSE TO OXYGEN CONTAINING COMPOUND 29 1381 5.458e-12 1.512e-10
169 DIGESTIVE SYSTEM DEVELOPMENT 12 148 6.296e-12 1.733e-10
170 ESTABLISHMENT OR MAINTENANCE OF APICAL BASAL CELL POLARITY 8 37 7.207e-12 1.961e-10
171 ESTABLISHMENT OR MAINTENANCE OF BIPOLAR CELL POLARITY 8 37 7.207e-12 1.961e-10
172 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 15 289 7.971e-12 2.156e-10
173 ANTERIOR POSTERIOR PATTERN SPECIFICATION 13 194 8.97e-12 2.413e-10
174 POSITIVE REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 6 12 9.423e-12 2.52e-10
175 REGULATION OF CELLULAR RESPONSE TO STRESS 21 691 1.031e-11 2.742e-10
176 REGULATION OF CYTOPLASMIC TRANSPORT 18 481 1.283e-11 3.392e-10
177 CELLULAR MACROMOLECULE LOCALIZATION 27 1234 1.413e-11 3.715e-10
178 MESONEPHROS DEVELOPMENT 10 90 1.675e-11 4.378e-10
179 REGULATION OF GROWTH 20 633 1.725e-11 4.485e-10
180 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 23 876 1.752e-11 4.528e-10
181 BLOOD VESSEL MORPHOGENESIS 16 364 1.844e-11 4.74e-10
182 KIDNEY EPITHELIUM DEVELOPMENT 11 125 2.047e-11 5.232e-10
183 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 16 370 2.354e-11 5.984e-10
184 REGULATION OF TRANSPORT 32 1804 2.711e-11 6.854e-10
185 NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT 7 26 2.87e-11 7.179e-10
186 NEGATIVE REGULATION OF MOLECULAR FUNCTION 25 1079 2.867e-11 7.179e-10
187 CELL JUNCTION ASSEMBLY 11 129 2.891e-11 7.193e-10
188 REGULATION OF ORGANELLE ORGANIZATION 26 1178 3.07e-11 7.598e-10
189 REGULATION OF MAP KINASE ACTIVITY 15 319 3.237e-11 7.97e-10
190 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 12 171 3.47e-11 8.497e-10
191 REPRODUCTION 27 1297 4.403e-11 1.073e-09
192 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 33 1977 6.003e-11 1.455e-09
193 CELL CYCLE 27 1316 6.122e-11 1.476e-09
194 RESPONSE TO ABIOTIC STIMULUS 24 1024 6.158e-11 1.477e-09
195 REGULATION OF HYDROLASE ACTIVITY 27 1327 7.389e-11 1.763e-09
196 PHOSPHORYLATION 26 1228 7.659e-11 1.818e-09
197 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 20 689 7.825e-11 1.848e-09
198 REGULATION OF BINDING 14 283 7.936e-11 1.865e-09
199 PARAXIAL MESODERM DEVELOPMENT 6 16 8.041e-11 1.88e-09
200 REGULATION OF CELL CYCLE 23 949 8.657e-11 2.014e-09
201 SENSORY ORGAN MORPHOGENESIS 13 239 1.227e-10 2.841e-09
202 FORMATION OF PRIMARY GERM LAYER 10 110 1.269e-10 2.924e-09
203 BICELLULAR TIGHT JUNCTION ASSEMBLY 7 32 1.434e-10 3.288e-09
204 CELL CYCLE PROCESS 24 1081 1.865e-10 4.254e-09
205 KIDNEY MORPHOGENESIS 9 82 2.026e-10 4.598e-09
206 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 15 365 2.135e-10 4.823e-09
207 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 18 573 2.23e-10 5.012e-09
208 REGULATION OF MESENCHYMAL CELL PROLIFERATION 7 34 2.275e-10 5.089e-09
209 MAMMARY GLAND DEVELOPMENT 10 117 2.349e-10 5.229e-09
210 NEGATIVE REGULATION OF CELL CYCLE 16 433 2.403e-10 5.324e-09
211 CELL DEATH 23 1001 2.477e-10 5.462e-09
212 MESODERM DEVELOPMENT 10 118 2.556e-10 5.611e-09
213 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 20 740 2.751e-10 6.011e-09
214 REGULATION OF JNK CASCADE 11 159 2.79e-10 6.067e-09
215 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 21 829 2.984e-10 6.458e-09
216 POSITIVE REGULATION OF MAP KINASE ACTIVITY 12 207 3.202e-10 6.897e-09
217 LOCOMOTION 24 1114 3.431e-10 7.358e-09
218 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 7 36 3.502e-10 7.475e-09
219 ENDOCRINE SYSTEM DEVELOPMENT 10 123 3.859e-10 8.199e-09
220 SKIN DEVELOPMENT 12 211 3.991e-10 8.441e-09
221 MIDBRAIN DEVELOPMENT 9 90 4.731e-10 9.961e-09
222 OSTEOBLAST DIFFERENTIATION 10 126 4.898e-10 1.026e-08
223 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 7 38 5.254e-10 1.096e-08
224 REGULATION OF CELLULAR COMPONENT MOVEMENT 20 771 5.627e-10 1.169e-08
225 REGULATION OF RESPONSE TO STRESS 27 1468 7.026e-10 1.453e-08
226 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 18 616 7.105e-10 1.463e-08
227 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 17 541 7.482e-10 1.527e-08
228 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 17 541 7.482e-10 1.527e-08
229 APICAL JUNCTION ASSEMBLY 7 40 7.701e-10 1.561e-08
230 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 9 95 7.718e-10 1.561e-08
231 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 10 134 8.983e-10 1.809e-08
232 REGULATION OF CELL ADHESION 18 629 9.902e-10 1.986e-08
233 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 7 43 1.316e-09 2.605e-08
234 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 6 24 1.31e-09 2.605e-08
235 BETA CATENIN TCF COMPLEX ASSEMBLY 7 43 1.316e-09 2.605e-08
236 NEGATIVE REGULATION OF GROWTH 12 236 1.436e-09 2.831e-08
237 POSITIVE REGULATION OF CATALYTIC ACTIVITY 27 1518 1.464e-09 2.875e-08
238 POSITIVE REGULATION OF LOCOMOTION 15 420 1.474e-09 2.882e-08
239 PROTEIN COMPLEX SUBUNIT ORGANIZATION 27 1527 1.666e-09 3.243e-08
240 ODONTOGENESIS 9 105 1.898e-09 3.679e-08
241 REGULATION OF FAT CELL DIFFERENTIATION 9 106 2.066e-09 3.988e-08
242 REGULATION OF ORGAN GROWTH 8 73 2.179e-09 4.19e-08
243 CELL CELL JUNCTION ASSEMBLY 8 74 2.434e-09 4.66e-08
244 POSITIVE REGULATION OF TRANSPORT 21 936 2.643e-09 5.04e-08
245 DEVELOPMENTAL INDUCTION 6 27 2.849e-09 5.366e-08
246 REGULATION OF CATENIN IMPORT INTO NUCLEUS 6 27 2.849e-09 5.366e-08
247 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 6 27 2.849e-09 5.366e-08
248 DIGESTIVE TRACT MORPHOGENESIS 7 48 2.948e-09 5.531e-08
249 PROTEIN LOCALIZATION 29 1805 3.144e-09 5.875e-08
250 EPIDERMIS DEVELOPMENT 12 253 3.157e-09 5.875e-08
251 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 10 153 3.28e-09 6.08e-08
252 CARDIAC SEPTUM MORPHOGENESIS 7 49 3.426e-09 6.325e-08
253 VENTRICULAR SEPTUM MORPHOGENESIS 6 28 3.612e-09 6.642e-08
254 RENAL TUBULE DEVELOPMENT 8 78 3.727e-09 6.827e-08
255 RESPONSE TO ACID CHEMICAL 13 319 4.174e-09 7.615e-08
256 NEPHRON DEVELOPMENT 9 115 4.27e-09 7.761e-08
257 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 6 29 4.536e-09 8.087e-08
258 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 6 29 4.536e-09 8.087e-08
259 REGULATION OF HEART MORPHOGENESIS 6 29 4.536e-09 8.087e-08
260 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 6 29 4.536e-09 8.087e-08
261 REGULATION OF DEPHOSPHORYLATION 10 158 4.479e-09 8.087e-08
262 CELLULAR RESPONSE TO LIPID 15 457 4.63e-09 8.222e-08
263 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 24 1275 5.03e-09 8.899e-08
264 REGULATION OF JUN KINASE ACTIVITY 8 81 5.053e-09 8.906e-08
265 SEX DIFFERENTIATION 12 266 5.546e-09 9.738e-08
266 MAMMARY GLAND EPITHELIUM DEVELOPMENT 7 53 6.052e-09 1.055e-07
267 MESONEPHRIC TUBULE MORPHOGENESIS 7 53 6.052e-09 1.055e-07
268 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 9 121 6.7e-09 1.163e-07
269 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 9 122 7.205e-09 1.246e-07
270 CARDIAC SEPTUM DEVELOPMENT 8 85 7.443e-09 1.283e-07
271 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 14 404 8.006e-09 1.375e-07
272 REGULATION OF ORGAN FORMATION 6 32 8.554e-09 1.456e-07
273 APPENDAGE DEVELOPMENT 10 169 8.573e-09 1.456e-07
274 LIMB DEVELOPMENT 10 169 8.573e-09 1.456e-07
275 ORGAN INDUCTION 5 16 9.607e-09 1.626e-07
276 SEGMENTATION 8 89 1.075e-08 1.813e-07
277 RESPONSE TO ORGANIC CYCLIC COMPOUND 20 917 1.087e-08 1.826e-07
278 CELL ACTIVATION 16 568 1.177e-08 1.97e-07
279 CELLULAR RESPONSE TO ACID CHEMICAL 10 175 1.198e-08 1.998e-07
280 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 11 228 1.251e-08 2.079e-07
281 CELL MOTILITY 19 835 1.368e-08 2.257e-07
282 LOCALIZATION OF CELL 19 835 1.368e-08 2.257e-07
283 REGULATION OF DEVELOPMENTAL GROWTH 12 289 1.399e-08 2.301e-07
284 STEM CELL PROLIFERATION 7 60 1.476e-08 2.409e-07
285 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 7 60 1.476e-08 2.409e-07
286 NEPHRON EPITHELIUM DEVELOPMENT 8 93 1.526e-08 2.483e-07
287 FOREBRAIN DEVELOPMENT 13 357 1.597e-08 2.589e-07
288 POSITIVE REGULATION OF STEM CELL PROLIFERATION 7 61 1.66e-08 2.682e-07
289 NEGATIVE REGULATION OF MUSCLE ORGAN DEVELOPMENT 6 36 1.81e-08 2.905e-07
290 NEGATIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 6 36 1.81e-08 2.905e-07
291 NOTOCHORD DEVELOPMENT 5 18 1.87e-08 2.99e-07
292 RESPONSE TO ALCOHOL 13 362 1.882e-08 2.999e-07
293 RHYTHMIC PROCESS 12 298 1.966e-08 3.122e-07
294 POSITIVE REGULATION OF JUN KINASE ACTIVITY 7 63 2.089e-08 3.307e-07
295 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 14 437 2.152e-08 3.394e-07
296 CELL CELL SIGNALING 18 767 2.178e-08 3.424e-07
297 NEGATIVE REGULATION OF CELL DEVELOPMENT 12 303 2.363e-08 3.702e-07
298 MESODERM MORPHOGENESIS 7 66 2.907e-08 4.539e-07
299 CARDIAC CHAMBER DEVELOPMENT 9 144 3.081e-08 4.794e-07
300 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 8 102 3.173e-08 4.921e-07
301 EAR DEVELOPMENT 10 195 3.359e-08 5.159e-07
302 DORSAL VENTRAL AXIS SPECIFICATION 5 20 3.359e-08 5.159e-07
303 NEGATIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 5 20 3.359e-08 5.159e-07
304 REGULATION OF MUSCLE TISSUE DEVELOPMENT 8 103 3.427e-08 5.228e-07
305 REGULATION OF MUSCLE ORGAN DEVELOPMENT 8 103 3.427e-08 5.228e-07
306 CARDIAC CHAMBER MORPHOGENESIS 8 104 3.698e-08 5.623e-07
307 MALE SEX DIFFERENTIATION 9 148 3.908e-08 5.923e-07
308 SINGLE ORGANISM CELL ADHESION 14 459 3.969e-08 5.997e-07
309 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 18 799 4.057e-08 6.11e-07
310 CELL DIVISION 14 460 4.078e-08 6.121e-07
311 NEURAL TUBE DEVELOPMENT 9 149 4.143e-08 6.198e-07
312 REGULATION OF MEMBRANE PERMEABILITY 7 70 4.405e-08 6.569e-07
313 PITUITARY GLAND DEVELOPMENT 6 42 4.764e-08 7.082e-07
314 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 7 71 4.868e-08 7.19e-07
315 ENDODERM DEVELOPMENT 7 71 4.868e-08 7.19e-07
316 ENDOCARDIAL CUSHION MORPHOGENESIS 5 22 5.662e-08 8.337e-07
317 PANCREAS DEVELOPMENT 7 73 5.918e-08 8.686e-07
318 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 6 44 6.362e-08 9.309e-07
319 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 7 75 7.153e-08 1.043e-06
320 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 8 115 8.133e-08 1.183e-06
321 DIENCEPHALON DEVELOPMENT 7 77 8.599e-08 1.243e-06
322 REGULATION OF BMP SIGNALING PATHWAY 7 77 8.599e-08 1.243e-06
323 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 8 117 9.304e-08 1.34e-06
324 SOMITE DEVELOPMENT 7 78 9.41e-08 1.351e-06
325 BONE MORPHOGENESIS 7 79 1.028e-07 1.472e-06
326 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 6 48 1.089e-07 1.554e-06
327 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 8 121 1.208e-07 1.72e-06
328 POSITIVE REGULATION OF FAT CELL DIFFERENTIATION 6 51 1.58e-07 2.241e-06
329 RESPONSE TO LITHIUM ION 5 27 1.703e-07 2.401e-06
330 AXIS ELONGATION 5 27 1.703e-07 2.401e-06
331 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 8 129 1.984e-07 2.781e-06
332 TUBE FORMATION 8 129 1.984e-07 2.781e-06
333 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 6 53 1.998e-07 2.792e-06
334 VENTRICULAR SEPTUM DEVELOPMENT 6 54 2.239e-07 3.12e-06
335 REGULATION OF MACROPHAGE CYTOKINE PRODUCTION 4 12 2.396e-07 3.327e-06
336 STEM CELL DIVISION 5 29 2.486e-07 3.443e-06
337 REGULATION OF KIDNEY DEVELOPMENT 6 55 2.504e-07 3.447e-06
338 CRANIAL SKELETAL SYSTEM DEVELOPMENT 6 55 2.504e-07 3.447e-06
339 AXIS SPECIFICATION 7 90 2.54e-07 3.486e-06
340 DORSAL VENTRAL PATTERN FORMATION 7 91 2.74e-07 3.75e-06
341 RESPONSE TO EXTERNAL STIMULUS 26 1821 2.764e-07 3.767e-06
342 REGULATION OF CELL CELL ADHESION 12 380 2.769e-07 3.767e-06
343 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 8 135 2.816e-07 3.82e-06
344 MITOCHONDRIAL MEMBRANE ORGANIZATION 7 92 2.955e-07 3.996e-06
345 EYE MORPHOGENESIS 8 136 2.98e-07 4.02e-06
346 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 7 93 3.183e-07 4.28e-06
347 NEURAL TUBE FORMATION 7 94 3.425e-07 4.593e-06
348 GDP METABOLIC PROCESS 4 13 3.448e-07 4.61e-06
349 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 7 95 3.683e-07 4.911e-06
350 VASCULOGENESIS 6 59 3.832e-07 5.095e-06
351 ENDOCARDIAL CUSHION DEVELOPMENT 5 32 4.168e-07 5.526e-06
352 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 8 143 4.378e-07 5.787e-06
353 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 12 397 4.413e-07 5.817e-06
354 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 10 258 4.569e-07 6.006e-06
355 EMBRYONIC DIGIT MORPHOGENESIS 6 61 4.686e-07 6.142e-06
356 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY INVOLVED IN NEURAL TUBE CLOSURE 4 14 4.809e-07 6.285e-06
357 EMBRYONIC AXIS SPECIFICATION 5 33 4.894e-07 6.343e-06
358 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 7 99 4.886e-07 6.343e-06
359 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 7 99 4.886e-07 6.343e-06
360 SOMITOGENESIS 6 62 5.168e-07 6.68e-06
361 ORGAN FORMATION 5 34 5.716e-07 7.367e-06
362 POSITIVE REGULATION OF PROTEIN IMPORT 7 104 6.837e-07 8.764e-06
363 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 7 104 6.837e-07 8.764e-06
364 MITOTIC CELL CYCLE 16 766 6.944e-07 8.877e-06
365 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 8 152 6.97e-07 8.886e-06
366 REGULATION OF DNA METABOLIC PROCESS 11 340 7.095e-07 9.02e-06
367 IMMUNE SYSTEM DEVELOPMENT 14 582 7.128e-07 9.038e-06
368 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 6 66 7.522e-07 9.485e-06
369 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 6 66 7.522e-07 9.485e-06
370 CELL CYCLE ARREST 8 154 7.697e-07 9.68e-06
371 REGULATION OF CYTOSKELETON ORGANIZATION 13 502 8.126e-07 1.019e-05
372 NEGATIVE REGULATION OF PHOSPHORYLATION 12 422 8.41e-07 1.052e-05
373 BONE DEVELOPMENT 8 156 8.488e-07 1.059e-05
374 PROTEIN LOCALIZATION TO SYNAPSE 4 16 8.679e-07 1.08e-05
375 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 6 68 8.992e-07 1.116e-05
376 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 10 282 1.027e-06 1.272e-05
377 RESPONSE TO DRUG 12 431 1.049e-06 1.295e-05
378 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 7 111 1.064e-06 1.309e-05
379 BRANCH ELONGATION OF AN EPITHELIUM 4 17 1.131e-06 1.374e-05
380 CELLULAR RESPONSE TO LITHIUM ION 4 17 1.131e-06 1.374e-05
381 NEGATIVE REGULATION OF STEM CELL PROLIFERATION 4 17 1.131e-06 1.374e-05
382 ESTABLISHMENT OF TISSUE POLARITY 4 17 1.131e-06 1.374e-05
383 NEGATIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 4 17 1.131e-06 1.374e-05
384 SKIN EPIDERMIS DEVELOPMENT 6 71 1.163e-06 1.409e-05
385 MEMBRANE ORGANIZATION 17 899 1.181e-06 1.427e-05
386 NEGATIVE REGULATION OF CELL ADHESION 9 223 1.268e-06 1.529e-05
387 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 6 73 1.372e-06 1.649e-05
388 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 8 167 1.42e-06 1.702e-05
389 ANGIOGENESIS 10 293 1.452e-06 1.736e-05
390 REGULATION OF PROTEIN BINDING 8 168 1.485e-06 1.771e-05
391 RECEPTOR CLUSTERING 5 41 1.499e-06 1.784e-05
392 PROTEIN COMPLEX BIOGENESIS 19 1132 1.515e-06 1.792e-05
393 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 7 117 1.517e-06 1.792e-05
394 PROTEIN COMPLEX ASSEMBLY 19 1132 1.515e-06 1.792e-05
395 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 11 368 1.537e-06 1.811e-05
396 GENITALIA DEVELOPMENT 5 42 1.695e-06 1.992e-05
397 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 15 724 1.783e-06 2.09e-05
398 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 5 43 1.911e-06 2.234e-05
399 T CELL DIFFERENTIATION 7 123 2.123e-06 2.476e-05
400 TRACHEA DEVELOPMENT 4 20 2.277e-06 2.642e-05
401 GMP METABOLIC PROCESS 4 20 2.277e-06 2.642e-05
402 ENDOCHONDRAL BONE MORPHOGENESIS 5 45 2.407e-06 2.779e-05
403 REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 5 45 2.407e-06 2.779e-05
404 REGULATION OF NEURON DIFFERENTIATION 13 554 2.424e-06 2.791e-05
405 RESPONSE TO OXYGEN LEVELS 10 311 2.477e-06 2.846e-05
406 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 7 126 2.494e-06 2.859e-05
407 WOUND HEALING 12 470 2.58e-06 2.949e-05
408 POSITIVE REGULATION OF BINDING 7 127 2.63e-06 2.999e-05
409 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 5 46 2.691e-06 3.061e-05
410 MACROMOLECULAR COMPLEX DISASSEMBLY 8 182 2.702e-06 3.066e-05
411 REGULATION OF PHOSPHATASE ACTIVITY 7 128 2.771e-06 3.122e-05
412 REGULATION OF CELL GROWTH 11 391 2.761e-06 3.122e-05
413 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 7 128 2.771e-06 3.122e-05
414 NEGATIVE REGULATION OF ORGAN GROWTH 4 21 2.802e-06 3.142e-05
415 COCHLEA MORPHOGENESIS 4 21 2.802e-06 3.142e-05
416 RESPONSE TO WOUNDING 13 563 2.892e-06 3.234e-05
417 HAIR CYCLE 6 83 2.927e-06 3.258e-05
418 MOLTING CYCLE 6 83 2.927e-06 3.258e-05
419 POSITIVE REGULATION OF DNA METABOLIC PROCESS 8 185 3.051e-06 3.388e-05
420 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 6 84 3.14e-06 3.478e-05
421 EPITHELIAL CELL DEVELOPMENT 8 186 3.176e-06 3.51e-05
422 MAINTENANCE OF CELL NUMBER 7 132 3.401e-06 3.745e-05
423 ACTIVIN RECEPTOR SIGNALING PATHWAY 4 22 3.412e-06 3.745e-05
424 SOMATIC STEM CELL DIVISION 4 22 3.412e-06 3.745e-05
425 REGULATION OF CELLULAR COMPONENT BIOGENESIS 15 767 3.614e-06 3.957e-05
426 REGULATION OF STEROID BIOSYNTHETIC PROCESS 5 49 3.701e-06 4.042e-05
427 CELL CYCLE PHASE TRANSITION 9 255 3.817e-06 4.15e-05
428 LEUKOCYTE CELL CELL ADHESION 9 255 3.817e-06 4.15e-05
429 NEGATIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 4 23 4.115e-06 4.443e-05
430 FACE DEVELOPMENT 5 50 4.096e-06 4.443e-05
431 REGULATION OF METANEPHROS DEVELOPMENT 4 23 4.115e-06 4.443e-05
432 PLACENTA DEVELOPMENT 7 138 4.568e-06 4.92e-05
433 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 14 684 4.703e-06 5.053e-05
434 LEUKOCYTE ACTIVATION 11 414 4.767e-06 5.111e-05
435 RESPONSE TO STEROL 4 24 4.92e-06 5.263e-05
436 NEURON DEVELOPMENT 14 687 4.944e-06 5.277e-05
437 RESPONSE TO HORMONE 16 893 5.056e-06 5.383e-05
438 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 8 199 5.234e-06 5.561e-05
439 INNER EAR MORPHOGENESIS 6 92 5.34e-06 5.66e-05
440 EPIDERMAL CELL DIFFERENTIATION 7 142 5.518e-06 5.835e-05
441 LYMPHOCYTE ACTIVATION 10 342 5.749e-06 6.065e-05
442 SYNAPSE ORGANIZATION 7 145 6.333e-06 6.667e-05
443 CELL CELL ADHESION 13 608 6.657e-06 6.992e-05
444 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 4 26 6.872e-06 7.185e-05
445 REGULATION OF HORMONE METABOLIC PROCESS 4 26 6.872e-06 7.185e-05
446 OUTFLOW TRACT MORPHOGENESIS 5 56 7.219e-06 7.532e-05
447 GLAND MORPHOGENESIS 6 97 7.259e-06 7.557e-05
448 REGULATION OF PROTEOLYSIS 14 711 7.314e-06 7.596e-05
449 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 8 209 7.503e-06 7.758e-05
450 LYMPHOCYTE DIFFERENTIATION 8 209 7.503e-06 7.758e-05
451 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 6 98 7.703e-06 7.93e-05
452 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 6 98 7.703e-06 7.93e-05
453 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 5 57 7.883e-06 8.097e-05
454 ACTIVATION OF PROTEIN KINASE ACTIVITY 9 279 7.902e-06 8.099e-05
455 EMBRYONIC PATTERN SPECIFICATION 5 58 8.594e-06 8.789e-05
456 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 8 213 8.618e-06 8.793e-05
457 MACROMOLECULAR COMPLEX ASSEMBLY 20 1398 8.687e-06 8.845e-05
458 CAMERA TYPE EYE MORPHOGENESIS 6 101 9.168e-06 9.314e-05
459 GASTRULATION WITH MOUTH FORMING SECOND 4 28 9.342e-06 9.429e-05
460 MORPHOGENESIS OF A POLARIZED EPITHELIUM 4 28 9.342e-06 9.429e-05
461 DOPAMINERGIC NEURON DIFFERENTIATION 4 28 9.342e-06 9.429e-05
462 REGULATION OF MITOCHONDRION ORGANIZATION 8 218 1.021e-05 0.0001026
463 RESPONSE TO ESTROGEN 8 218 1.021e-05 0.0001026
464 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 6 103 1.026e-05 0.0001029
465 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 4 29 1.08e-05 0.000108
466 LEUKOCYTE DIFFERENTIATION 9 292 1.138e-05 0.0001136
467 NEURON PROJECTION DEVELOPMENT 12 545 1.158e-05 0.0001154
468 CARDIAC VENTRICLE DEVELOPMENT 6 106 1.211e-05 0.0001201
469 FAT CELL DIFFERENTIATION 6 106 1.211e-05 0.0001201
470 NEGATIVE REGULATION OF TRANSPORT 11 458 1.234e-05 0.0001222
471 REGULATION OF DNA REPLICATION 7 161 1.257e-05 0.0001242
472 REGULATION OF EPITHELIAL CELL MIGRATION 7 166 1.533e-05 0.0001511
473 REGULATION OF CYTOKINE PRODUCTION 12 563 1.6e-05 0.0001574
474 POSITIVE REGULATION OF BMP SIGNALING PATHWAY 4 32 1.617e-05 0.0001587
475 POSITIVE REGULATION OF NEURON DIFFERENTIATION 9 306 1.651e-05 0.0001618
476 EAR MORPHOGENESIS 6 112 1.659e-05 0.0001622
477 OVULATION CYCLE 6 113 1.745e-05 0.0001702
478 NEURON FATE COMMITMENT 5 67 1.751e-05 0.0001704
479 NEGATIVE REGULATION OF CELL GROWTH 7 170 1.788e-05 0.0001737
480 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 4 33 1.833e-05 0.0001773
481 POSITIVE REGULATION OF EMBRYONIC DEVELOPMENT 4 33 1.833e-05 0.0001773
482 REGULATION OF PEPTIDASE ACTIVITY 10 392 1.88e-05 0.0001815
483 REGULATION OF ACTIN FILAMENT BASED PROCESS 9 312 1.925e-05 0.0001851
484 POSITIVE REGULATION OF GROWTH 8 238 1.926e-05 0.0001851
485 BRAIN MORPHOGENESIS 4 34 2.07e-05 0.0001986
486 GLIOGENESIS 7 175 2.156e-05 0.0002065
487 NEURAL PRECURSOR CELL PROLIFERATION 5 70 2.169e-05 0.0002068
488 MUSCLE ORGAN MORPHOGENESIS 5 70 2.169e-05 0.0002068
489 NEGATIVE REGULATION OF CARDIAC MUSCLE TISSUE GROWTH 3 12 2.285e-05 0.0002157
490 ANATOMICAL STRUCTURE REGRESSION 3 12 2.285e-05 0.0002157
491 TRACHEA MORPHOGENESIS 3 12 2.285e-05 0.0002157
492 MAMMARY GLAND EPITHELIAL CELL PROLIFERATION 3 12 2.285e-05 0.0002157
493 NEGATIVE REGULATION OF HEART GROWTH 3 12 2.285e-05 0.0002157
494 MITOCHONDRIAL TRANSPORT 7 177 2.32e-05 0.0002185
495 CELL FATE SPECIFICATION 5 71 2.325e-05 0.0002185
496 NEURON PROJECTION MORPHOGENESIS 10 402 2.332e-05 0.0002188
497 POSITIVE REGULATION OF CELL CYCLE PROCESS 8 247 2.513e-05 0.0002353
498 PROTEIN TARGETING 10 406 2.538e-05 0.0002366
499 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 10 406 2.538e-05 0.0002366
500 HEAD MORPHOGENESIS 4 36 2.61e-05 0.0002429
501 RESPONSE TO STEROID HORMONE 11 497 2.626e-05 0.0002439
502 POSITIVE REGULATION OF PROTEIN BINDING 5 73 2.662e-05 0.0002467
503 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 6 122 2.697e-05 0.0002495
504 NEGATIVE REGULATION OF KINASE ACTIVITY 8 250 2.739e-05 0.0002529
505 REGULATION OF STEROID METABOLIC PROCESS 5 74 2.844e-05 0.000262
506 REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 4 37 2.915e-05 0.0002676
507 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 4 37 2.915e-05 0.0002676
508 TYPE B PANCREATIC CELL DEVELOPMENT 3 13 2.96e-05 0.0002711
509 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 5 75 3.036e-05 0.0002765
510 BIOLOGICAL ADHESION 16 1032 3.036e-05 0.0002765
511 NEURAL CREST CELL DIFFERENTIATION 5 75 3.036e-05 0.0002765
512 POSITIVE REGULATION OF CELL CYCLE 9 332 3.136e-05 0.000285
513 NEGATIVE REGULATION OF DEPHOSPHORYLATION 5 77 3.449e-05 0.0003128
514 COCHLEA DEVELOPMENT 4 39 3.604e-05 0.0003256
515 GLANDULAR EPITHELIAL CELL DIFFERENTIATION 4 39 3.604e-05 0.0003256
516 CELLULAR COMPONENT DISASSEMBLY 11 515 3.633e-05 0.0003276
517 CELL MIGRATION INVOLVED IN GASTRULATION 3 14 3.754e-05 0.0003366
518 CONVERGENT EXTENSION 3 14 3.754e-05 0.0003366
519 RESPONSE TO LAMINAR FLUID SHEAR STRESS 3 14 3.754e-05 0.0003366
520 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 8 262 3.823e-05 0.0003421
521 MAMMARY GLAND MORPHOGENESIS 4 40 3.99e-05 0.0003563
522 AGING 8 264 4.035e-05 0.0003596
523 CELL CYCLE CHECKPOINT 7 194 4.171e-05 0.0003711
524 POSITIVE REGULATION OF CELL DIVISION 6 132 4.204e-05 0.0003733
525 MUSCLE STRUCTURE DEVELOPMENT 10 432 4.291e-05 0.0003803
526 REGULATION OF FIBROBLAST PROLIFERATION 5 81 4.405e-05 0.0003889
527 LUNG ALVEOLUS DEVELOPMENT 4 41 4.405e-05 0.0003889
528 REGULATION OF EPITHELIAL CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 3 15 4.676e-05 0.0004113
529 ENDOCARDIAL CUSHION FORMATION 3 15 4.676e-05 0.0004113
530 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 10 437 4.727e-05 0.000415
531 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 9 351 4.831e-05 0.0004233
532 REGULATION OF HEART GROWTH 4 42 4.851e-05 0.0004243
533 EMBRYONIC PLACENTA DEVELOPMENT 5 83 4.954e-05 0.0004325
534 GLIAL CELL DIFFERENTIATION 6 136 4.969e-05 0.0004329
535 REGULATION OF CELL DIVISION 8 272 4.981e-05 0.0004332
536 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 7 200 5.06e-05 0.0004392
537 NEGATIVE REGULATION OF CELL CELL ADHESION 6 138 5.391e-05 0.0004662
538 CELL CYCLE G2 M PHASE TRANSITION 6 138 5.391e-05 0.0004662
539 MITOTIC CELL CYCLE CHECKPOINT 6 139 5.612e-05 0.0004845
540 LABYRINTHINE LAYER DEVELOPMENT 4 44 5.84e-05 0.0005015
541 BODY MORPHOGENESIS 4 44 5.84e-05 0.0005015
542 CARDIAC MUSCLE TISSUE DEVELOPMENT 6 140 5.841e-05 0.0005015
543 POSITIVE REGULATION OF DNA REPLICATION 5 86 5.876e-05 0.0005035
544 TISSUE REMODELING 5 87 6.211e-05 0.0005312
545 LUNG MORPHOGENESIS 4 45 6.387e-05 0.0005433
546 THYMOCYTE AGGREGATION 4 45 6.387e-05 0.0005433
547 T CELL DIFFERENTIATION IN THYMUS 4 45 6.387e-05 0.0005433
548 ESTABLISHMENT OF CELL POLARITY 5 88 6.56e-05 0.000555
549 OVULATION CYCLE PROCESS 5 88 6.56e-05 0.000555
550 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 5 88 6.56e-05 0.000555
551 EPITHELIAL CELL PROLIFERATION 5 89 6.924e-05 0.0005847
552 NEGATIVE REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 3 17 6.94e-05 0.000585
553 GUANOSINE CONTAINING COMPOUND METABOLIC PROCESS 4 46 6.969e-05 0.0005864
554 ENDOTHELIUM DEVELOPMENT 5 90 7.304e-05 0.0006123
555 REGULATION OF GLIOGENESIS 5 90 7.304e-05 0.0006123
556 RESPONSE TO ESTRADIOL 6 146 7.376e-05 0.0006172
557 REGULATION OF CELL CYCLE PROCESS 11 558 7.473e-05 0.0006242
558 POSITIVE REGULATION OF GLIOGENESIS 4 47 7.59e-05 0.0006329
559 TAXIS 10 464 7.788e-05 0.0006483
560 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 10 465 7.928e-05 0.0006588
561 POSITIVE REGULATION OF CELL ADHESION 9 376 8.192e-05 0.0006794
562 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 7 216 8.214e-05 0.0006801
563 ANTERIOR POSTERIOR AXIS SPECIFICATION 4 48 8.249e-05 0.0006818
564 GLANDULAR EPITHELIAL CELL DEVELOPMENT 3 18 8.3e-05 0.0006823
565 REGULATION OF HORMONE BIOSYNTHETIC PROCESS 3 18 8.3e-05 0.0006823
566 PERICARDIUM DEVELOPMENT 3 18 8.3e-05 0.0006823
567 REGULATION OF MITOTIC CELL CYCLE 10 468 8.361e-05 0.0006861
568 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 6 153 9.555e-05 0.0007827
569 ENDODERM FORMATION 4 50 9.692e-05 0.0007926
570 ENTRAINMENT OF CIRCADIAN CLOCK BY PHOTOPERIOD 3 19 9.821e-05 0.0007989
571 ENTEROENDOCRINE CELL DIFFERENTIATION 3 19 9.821e-05 0.0007989
572 POSITIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 3 19 9.821e-05 0.0007989
573 AMEBOIDAL TYPE CELL MIGRATION 6 154 9.904e-05 0.0008043
574 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 8 303 0.0001058 0.0008573
575 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 6 156 0.0001063 0.0008605
576 REGULATION OF IMMUNE SYSTEM PROCESS 18 1403 0.0001088 0.0008788
577 TONGUE DEVELOPMENT 3 20 0.0001151 0.0009269
578 TELENCEPHALON DEVELOPMENT 7 228 0.0001151 0.0009269
579 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 5 100 0.0001205 0.0009682
580 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 4 53 0.0001219 0.0009762
581 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 4 53 0.0001219 0.0009762
582 REGENERATION 6 161 0.0001264 0.001007
583 KERATINOCYTE DIFFERENTIATION 5 101 0.0001263 0.001007
584 REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 5 101 0.0001263 0.001007
585 REGULATION OF LEUKOCYTE DIFFERENTIATION 7 232 0.0001282 0.001019
586 CARDIAC MUSCLE TISSUE MORPHOGENESIS 4 54 0.0001312 0.001041
587 REGULATION OF VASCULATURE DEVELOPMENT 7 233 0.0001316 0.001043
588 REGULATION OF GENE SILENCING BY RNA 3 21 0.0001339 0.001049
589 MALE GENITALIA DEVELOPMENT 3 21 0.0001339 0.001049
590 CHONDROCYTE DEVELOPMENT 3 21 0.0001339 0.001049
591 CELL AGGREGATION 3 21 0.0001339 0.001049
592 NEGATIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 3 21 0.0001339 0.001049
593 REGULATION OF POSTTRANSCRIPTIONAL GENE SILENCING 3 21 0.0001339 0.001049
594 CARTILAGE CONDENSATION 3 21 0.0001339 0.001049
595 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 4 55 0.0001409 0.001102
596 NEGATIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 22 0.0001545 0.001204
597 EMBRYONIC PLACENTA MORPHOGENESIS 3 22 0.0001545 0.001204
598 RESPONSE TO RADIATION 9 413 0.0001663 0.001294
599 REGULATION OF MICROTUBULE BASED PROCESS 7 243 0.0001706 0.001323
600 POSITIVE REGULATION OF CELL CELL ADHESION 7 243 0.0001706 0.001323
601 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 23 0.000177 0.001368
602 POSITIVE REGULATION OF COLLAGEN METABOLIC PROCESS 3 23 0.000177 0.001368
603 NEGATIVE REGULATION OF PEPTIDASE ACTIVITY 7 245 0.0001794 0.001384
604 REGULATION OF GLIAL CELL DIFFERENTIATION 4 59 0.0001853 0.001428
605 NEGATIVE REGULATION OF PROTEOLYSIS 8 329 0.000186 0.00143
606 PHOTOPERIODISM 3 24 0.0002016 0.00154
607 NEGATIVE REGULATION OF STEROID METABOLIC PROCESS 3 24 0.0002016 0.00154
608 RESPONSE TO METAL ION 8 333 0.0002019 0.00154
609 REGULATION OF ODONTOGENESIS 3 24 0.0002016 0.00154
610 REGULATION OF PROTEIN PHOSPHATASE TYPE 2A ACTIVITY 3 24 0.0002016 0.00154
611 REGULATION OF ENDOTHELIAL CELL MIGRATION 5 114 0.0002228 0.001694
612 NOTCH SIGNALING PATHWAY 5 114 0.0002228 0.001694
613 CELL PART MORPHOGENESIS 11 633 0.0002254 0.001711
614 LENS FIBER CELL DIFFERENTIATION 3 25 0.0002283 0.001716
615 LUNG CELL DIFFERENTIATION 3 25 0.0002283 0.001716
616 FOREBRAIN REGIONALIZATION 3 25 0.0002283 0.001716
617 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 3 25 0.0002283 0.001716
618 POSITIVE REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 3 25 0.0002283 0.001716
619 EPITHELIAL CELL APOPTOTIC PROCESS 3 25 0.0002283 0.001716
620 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 13 867 0.0002524 0.001894
621 RIBONUCLEOSIDE DIPHOSPHATE METABOLIC PROCESS 4 64 0.000254 0.001903
622 ENTRAINMENT OF CIRCADIAN CLOCK 3 26 0.0002572 0.001921
623 REGULATION OF P38MAPK CASCADE 3 26 0.0002572 0.001921
624 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 5 118 0.0002616 0.001951
625 POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 5 119 0.0002721 0.002025
626 NEGATIVE REGULATION OF LOCOMOTION 7 263 0.0002764 0.002051
627 CELLULAR RESPONSE TO ABIOTIC STIMULUS 7 263 0.0002764 0.002051
628 SOMATIC STEM CELL POPULATION MAINTENANCE 4 66 0.000286 0.002119
629 REGULATION OF PROTEIN KINASE B SIGNALING 5 121 0.0002939 0.002174
630 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 4 67 0.0003031 0.002239
631 LOCALIZATION WITHIN MEMBRANE 5 122 0.0003053 0.002251
632 PROTEIN DEPHOSPHORYLATION 6 190 0.00031 0.002283
633 REGULATION OF NEUROBLAST PROLIFERATION 3 28 0.0003218 0.002362
634 MAMMARY GLAND DUCT MORPHOGENESIS 3 28 0.0003218 0.002362
635 REGULATION OF NEURON APOPTOTIC PROCESS 6 192 0.0003279 0.002403
636 DEVELOPMENTAL MATURATION 6 193 0.0003371 0.002466
637 NEGATIVE REGULATION OF OSSIFICATION 4 69 0.0003394 0.002475
638 SYNAPSE ASSEMBLY 4 69 0.0003394 0.002475
639 EPIDERMIS MORPHOGENESIS 3 29 0.0003577 0.002596
640 NEGATIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 3 29 0.0003577 0.002596
641 REGULATION OF OLIGODENDROCYTE DIFFERENTIATION 3 29 0.0003577 0.002596
642 MUSCLE TISSUE DEVELOPMENT 7 275 0.0003618 0.002623
643 CELL PROJECTION ORGANIZATION 13 902 0.0003691 0.002671
644 REGULATION OF LIPID BIOSYNTHETIC PROCESS 5 128 0.000381 0.002753
645 REGULATION OF CHROMOSOME ORGANIZATION 7 278 0.0003862 0.002786
646 IMMUNE SYSTEM PROCESS 21 1984 0.0003967 0.002857
647 ENERGY RESERVE METABOLIC PROCESS 4 72 0.0003995 0.002868
648 ENDOTHELIAL CELL DIFFERENTIATION 4 72 0.0003995 0.002868
649 REGULATION OF LIPID METABOLIC PROCESS 7 282 0.0004207 0.00301
650 EMBRYONIC HEART TUBE DEVELOPMENT 4 73 0.0004211 0.00301
651 REGULATION OF PLASMA MEMBRANE ORGANIZATION 4 73 0.0004211 0.00301
652 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 5 131 0.0004237 0.003023
653 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 8 372 0.0004243 0.003023
654 DNA TEMPLATED TRANSCRIPTION INITIATION 6 202 0.0004296 0.003057
655 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 5 133 0.0004542 0.003226
656 PROTEIN LOCALIZATION TO MEMBRANE 8 376 0.0004554 0.00323
657 NEURON PROJECTION GUIDANCE 6 205 0.0004645 0.00329
658 ARTERY DEVELOPMENT 4 75 0.0004668 0.003301
659 NEGATIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 3 32 0.0004805 0.003377
660 SALIVARY GLAND DEVELOPMENT 3 32 0.0004805 0.003377
661 POSITIVE REGULATION OF GLIAL CELL DIFFERENTIATION 3 32 0.0004805 0.003377
662 PATTERNING OF BLOOD VESSELS 3 32 0.0004805 0.003377
663 CIRCADIAN RHYTHM 5 137 0.00052 0.003644
664 HINDBRAIN DEVELOPMENT 5 137 0.00052 0.003644
665 POSITIVE REGULATION OF PROTEIN SECRETION 6 211 0.0005409 0.003785
666 LUNG EPITHELIUM DEVELOPMENT 3 34 0.0005757 0.00401
667 RESPONSE TO FLUID SHEAR STRESS 3 34 0.0005757 0.00401
668 HEART VALVE DEVELOPMENT 3 34 0.0005757 0.00401
669 NEGATIVE REGULATION OF PROTEIN PROCESSING 3 35 0.0006275 0.004332
670 METANEPHROS DEVELOPMENT 4 81 0.0006251 0.004332
671 BONE REMODELING 3 35 0.0006275 0.004332
672 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 4 81 0.0006251 0.004332
673 NEGATIVE REGULATION OF PROTEIN MATURATION 3 35 0.0006275 0.004332
674 RESPONSE TO IRON ION 3 35 0.0006275 0.004332
675 EXTRACELLULAR STRUCTURE ORGANIZATION 7 304 0.0006572 0.004531
676 RESPONSE TO IONIZING RADIATION 5 145 0.0006729 0.004625
677 NEGATIVE REGULATION OF MAPK CASCADE 5 145 0.0006729 0.004625
678 POSITIVE REGULATION OF PROTEIN ACETYLATION 3 36 0.0006821 0.004681
679 ORGAN REGENERATION 4 83 0.0006854 0.004697
680 REGULATION OF PROTEIN STABILITY 6 221 0.0006895 0.004718
681 NUCLEOSIDE DIPHOSPHATE METABOLIC PROCESS 4 84 0.000717 0.004899
682 PEPTIDYL SERINE MODIFICATION 5 148 0.0007382 0.005029
683 POSITIVE REGULATION OF CELL GROWTH 5 148 0.0007382 0.005029
684 POSITIVE REGULATION OF CHROMATIN MODIFICATION 4 85 0.0007497 0.0051
685 REGULATION OF HEMOPOIESIS 7 314 0.0007948 0.005399
686 BONE MINERALIZATION 3 38 0.0008004 0.005421
687 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 38 0.0008004 0.005421
688 RESPONSE TO NITROGEN COMPOUND 12 859 0.0008279 0.005599
689 REGULATION OF GENE EXPRESSION EPIGENETIC 6 229 0.0008298 0.005604
690 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 4 88 0.000854 0.005759
691 REGULATION OF CELL ADHESION MEDIATED BY INTEGRIN 3 39 0.0008641 0.005818
692 ENDOCRINE PANCREAS DEVELOPMENT 3 40 0.0009309 0.006241
693 ENDODERMAL CELL DIFFERENTIATION 3 40 0.0009309 0.006241
694 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 3 40 0.0009309 0.006241
695 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 5 156 0.0009353 0.006262
696 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 3 41 0.001001 0.006653
697 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 3 41 0.001001 0.006653
698 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 3 41 0.001001 0.006653
699 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 3 41 0.001001 0.006653
700 PROSTATE GLAND DEVELOPMENT 3 41 0.001001 0.006653
701 REGULATION OF DNA BINDING 4 93 0.00105 0.006969
702 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 3 42 0.001074 0.0071
703 POSITIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 3 42 0.001074 0.0071
704 POSTTRANSCRIPTIONAL GENE SILENCING 3 42 0.001074 0.0071
705 REGULATION OF DNA BIOSYNTHETIC PROCESS 4 94 0.001093 0.007211
706 POSITIVE REGULATION OF HEMOPOIESIS 5 163 0.001138 0.007488
707 CELLULAR RESPONSE TO BIOTIC STIMULUS 5 163 0.001138 0.007488
708 MORPHOGENESIS OF AN EPITHELIAL SHEET 3 43 0.001151 0.007552
709 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 3 43 0.001151 0.007552
710 CELL SUBSTRATE ADHESION 5 164 0.001169 0.007662
711 MYELOID LEUKOCYTE DIFFERENTIATION 4 96 0.001182 0.007733
712 ENDOCARDIUM DEVELOPMENT 2 11 0.001219 0.007912
713 LATERAL MESODERM DEVELOPMENT 2 11 0.001219 0.007912
714 POSITIVE REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 2 11 0.001219 0.007912
715 EPITHELIAL TO MESENCHYMAL TRANSITION INVOLVED IN ENDOCARDIAL CUSHION FORMATION 2 11 0.001219 0.007912
716 REGULATION OF ODONTOGENESIS OF DENTIN CONTAINING TOOTH 2 11 0.001219 0.007912
717 SINGLE ORGANISM CELLULAR LOCALIZATION 12 898 0.001214 0.007912
718 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 4 97 0.001228 0.007957
719 NEGATIVE REGULATION OF LIPID BIOSYNTHETIC PROCESS 3 44 0.001231 0.007964
720 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 5 166 0.001234 0.007974
721 RESPONSE TO EXTRACELLULAR STIMULUS 8 441 0.00128 0.008259
722 INTRACELLULAR PROTEIN TRANSPORT 11 781 0.001291 0.008318
723 POSITIVE REGULATION OF HYDROLASE ACTIVITY 12 905 0.001297 0.008346
724 RESPONSE TO CARBOHYDRATE 5 168 0.001301 0.008362
725 SUBSTANTIA NIGRA DEVELOPMENT 3 45 0.001314 0.008422
726 EXOCRINE SYSTEM DEVELOPMENT 3 45 0.001314 0.008422
727 REGULATION OF NEURON DEATH 6 252 0.001358 0.00869
728 NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY 5 170 0.001371 0.008763
729 CELLULAR IRON ION HOMEOSTASIS 3 46 0.001401 0.008917
730 PEPTIDYL THREONINE MODIFICATION 3 46 0.001401 0.008917
731 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 3 46 0.001401 0.008917
732 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 8 448 0.001414 0.008988
733 ANTERIOR POSTERIOR AXIS SPECIFICATION EMBRYO 2 12 0.001458 0.009158
734 CARTILAGE MORPHOGENESIS 2 12 0.001458 0.009158
735 POSITIVE REGULATION OF DNA DEPENDENT DNA REPLICATION 2 12 0.001458 0.009158
736 HEART FORMATION 2 12 0.001458 0.009158
737 MAINTENANCE OF CELL POLARITY 2 12 0.001458 0.009158
738 TRIPARTITE REGIONAL SUBDIVISION 2 12 0.001458 0.009158
739 POSITIVE REGULATION OF ASTROCYTE DIFFERENTIATION 2 12 0.001458 0.009158
740 REGULATION OF GTPASE ACTIVITY 10 673 0.001455 0.009158
741 LENS FIBER CELL DEVELOPMENT 2 12 0.001458 0.009158
742 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 3 47 0.001491 0.009351
743 REGULATION OF CIRCADIAN RHYTHM 4 103 0.001533 0.0096
744 COLUMNAR CUBOIDAL EPITHELIAL CELL DEVELOPMENT 3 48 0.001585 0.0099
745 POSITIVE REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 3 48 0.001585 0.0099
746 RESPONSE TO CORTICOSTEROID 5 176 0.001598 0.009965
NumGOOverlapSizeP ValueAdj. P Value
1 FRIZZLED BINDING 12 36 8.357e-20 7.763e-17
2 RECEPTOR BINDING 38 1476 7.355e-19 3.417e-16
3 TRANSFORMING GROWTH FACTOR BETA RECEPTOR BINDING 12 50 7.675e-18 2.377e-15
4 WNT ACTIVATED RECEPTOR ACTIVITY 8 22 6.33e-14 1.176e-11
5 ENZYME BINDING 35 1737 5.09e-14 1.176e-11
6 PROTEIN DOMAIN SPECIFIC BINDING 22 624 1.586e-13 2.456e-11
7 BETA CATENIN BINDING 11 84 2.407e-13 3.194e-11
8 SMAD BINDING 10 72 1.685e-12 1.739e-10
9 WNT PROTEIN BINDING 8 31 1.508e-12 1.739e-10
10 I SMAD BINDING 6 11 4.73e-12 4.394e-10
11 KINASE BINDING 19 606 6.779e-11 5.725e-09
12 G PROTEIN COUPLED RECEPTOR BINDING 13 259 3.313e-10 2.564e-08
13 IONOTROPIC GLUTAMATE RECEPTOR BINDING 6 23 9.866e-10 7.05e-08
14 GAMMA CATENIN BINDING 5 12 1.769e-09 1.174e-07
15 GROWTH FACTOR ACTIVITY 10 160 5.059e-09 3.133e-07
16 MACROMOLECULAR COMPLEX BINDING 25 1399 6.368e-09 3.697e-07
17 CYTOKINE RECEPTOR BINDING 12 271 6.833e-09 3.734e-07
18 RECEPTOR SIGNALING PROTEIN ACTIVITY 10 172 1.015e-08 5.239e-07
19 PDZ DOMAIN BINDING 8 90 1.176e-08 5.748e-07
20 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE ACTIVITY 5 17 1.356e-08 6.298e-07
21 PROTEIN C TERMINUS BINDING 10 186 2.145e-08 9.09e-07
22 GLUTAMATE RECEPTOR BINDING 6 37 2.153e-08 9.09e-07
23 UBIQUITIN LIKE PROTEIN LIGASE BINDING 11 264 5.638e-08 2.277e-06
24 PROTEIN COMPLEX BINDING 19 935 8.214e-08 3.179e-06
25 CYTOKINE ACTIVITY 10 219 1.002e-07 3.722e-06
26 GUANYLATE KINASE ACTIVITY 4 12 2.396e-07 8.56e-06
27 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 7 92 2.955e-07 1.017e-05
28 REGULATORY REGION NUCLEIC ACID BINDING 17 818 3.19e-07 1.047e-05
29 MOLECULAR FUNCTION REGULATOR 22 1353 3.268e-07 1.047e-05
30 KINASE ACTIVITY 17 842 4.779e-07 1.48e-05
31 RECEPTOR SERINE THREONINE KINASE BINDING 4 15 6.533e-07 1.958e-05
32 PHOSPHATASE BINDING 8 162 1.129e-06 3.278e-05
33 PROTEIN DIMERIZATION ACTIVITY 19 1149 1.889e-06 5.318e-05
34 PROTEIN HETERODIMERIZATION ACTIVITY 12 468 2.469e-06 6.746e-05
35 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 17 992 4.46e-06 0.0001184
36 NUCLEOTIDE KINASE ACTIVITY 4 24 4.92e-06 0.000127
37 SIGNAL TRANSDUCER ACTIVITY 23 1731 5.447e-06 0.0001368
38 TRANSCRIPTION FACTOR BINDING 12 524 7.811e-06 0.000191
39 PROTEIN SERINE THREONINE KINASE ACTIVITY 11 445 9.428e-06 0.0002246
40 PROTEIN KINASE ACTIVITY 13 640 1.151e-05 0.0002674
41 ENZYME REGULATOR ACTIVITY 16 959 1.236e-05 0.0002801
42 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 18 1199 1.39e-05 0.0003075
43 PROTEIN PHOSPHATASE BINDING 6 120 2.456e-05 0.0005306
44 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 9 328 2.852e-05 0.0006022
45 ARMADILLO REPEAT DOMAIN BINDING 3 13 2.96e-05 0.0006111
46 CELL ADHESION MOLECULE BINDING 7 186 3.189e-05 0.000644
47 PHOSPHOTRANSFERASE ACTIVITY PHOSPHATE GROUP AS ACCEPTOR 4 40 3.99e-05 0.0007887
48 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 5 81 4.405e-05 0.0008526
49 TRANSFORMING GROWTH FACTOR BETA BINDING 3 16 5.736e-05 0.001087
50 CORE PROMOTER PROXIMAL REGION DNA BINDING 9 371 7.396e-05 0.001374
51 CYTOKINE BINDING 5 92 8.111e-05 0.001474
52 NUCLEOBASE CONTAINING COMPOUND KINASE ACTIVITY 4 48 8.249e-05 0.001474
53 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 7 226 0.0001089 0.00191
54 GLYCOPROTEIN BINDING 5 101 0.0001263 0.002172
55 PROTEIN PHOSPHATASE TYPE 2A REGULATOR ACTIVITY 3 21 0.0001339 0.002261
56 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 5 104 0.000145 0.002405
57 R SMAD BINDING 3 23 0.000177 0.002835
58 CYSTEINE TYPE ENDOPEPTIDASE INHIBITOR ACTIVITY INVOLVED IN APOPTOTIC PROCESS 3 23 0.000177 0.002835
59 ION CHANNEL BINDING 5 111 0.0001968 0.003098
60 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 11 629 0.0002134 0.003304
61 CHROMATIN BINDING 9 435 0.0002445 0.003724
62 KINASE REGULATOR ACTIVITY 6 186 0.0002766 0.004079
63 RECEPTOR ACTIVITY 19 1649 0.0002757 0.004079
64 CADHERIN BINDING 3 28 0.0003218 0.004599
65 GROWTH FACTOR BINDING 5 123 0.0003171 0.004599
66 TRANSCRIPTION COREPRESSOR ACTIVITY 6 221 0.0006895 0.009706
NumGOOverlapSizeP ValueAdj. P Value
1 APICAL JUNCTION COMPLEX 14 128 1.435e-15 8.382e-13
2 CELL JUNCTION 30 1151 7.62e-15 2.225e-12
3 CELL CELL JUNCTION 17 383 3.456e-12 6.728e-10
4 WNT SIGNALOSOME 6 11 4.73e-12 6.905e-10
5 PLASMA MEMBRANE PROTEIN COMPLEX 17 510 3.04e-10 3.55e-08
6 PLASMA MEMBRANE RECEPTOR COMPLEX 11 175 7.777e-10 7.57e-08
7 ANCHORING JUNCTION 16 489 1.402e-09 1.17e-07
8 EXTRACELLULAR MATRIX 15 426 1.788e-09 1.306e-07
9 PHOSPHATASE COMPLEX 7 48 2.948e-09 1.913e-07
10 BETA CATENIN DESTRUCTION COMPLEX 5 14 4.437e-09 2.591e-07
11 CELL SURFACE 18 757 1.782e-08 9.461e-07
12 TRANSCRIPTION FACTOR COMPLEX 12 298 1.966e-08 9.568e-07
13 CYTOPLASMIC VESICLE PART 16 601 2.59e-08 1.164e-06
14 PROTEIN PHOSPHATASE TYPE 2A COMPLEX 5 20 3.359e-08 1.401e-06
15 EXTRACELLULAR SPACE 23 1376 1.007e-07 3.919e-06
16 PROTEINACEOUS EXTRACELLULAR MATRIX 12 356 1.374e-07 5.014e-06
17 NEURON PROJECTION 18 942 4.688e-07 1.567e-05
18 RECEPTOR COMPLEX 11 327 4.831e-07 1.567e-05
19 MEMBRANE MICRODOMAIN 10 288 1.243e-06 3.82e-05
20 MEMBRANE REGION 19 1134 1.555e-06 4.542e-05
21 INTRACELLULAR VESICLE 20 1259 1.79e-06 4.977e-05
22 SOMATODENDRITIC COMPARTMENT 14 650 2.612e-06 6.933e-05
23 CELL SUBSTRATE JUNCTION 11 398 3.273e-06 8.31e-05
24 LATERAL PLASMA MEMBRANE 5 50 4.096e-06 9.968e-05
25 EXCITATORY SYNAPSE 8 197 4.859e-06 0.0001135
26 NEURONAL POSTSYNAPTIC DENSITY 5 53 5.485e-06 0.0001232
27 VESICLE MEMBRANE 12 512 6.182e-06 0.0001289
28 CELL CELL ADHERENS JUNCTION 5 54 6.022e-06 0.0001289
29 MEMBRANE PROTEIN COMPLEX 17 1020 6.448e-06 0.0001299
30 NEURON PART 19 1265 7.637e-06 0.0001487
31 DENDRITE 11 451 1.069e-05 0.0002013
32 POSTSYNAPSE 10 378 1.375e-05 0.0002444
33 CYTOSKELETON 24 1967 1.381e-05 0.0002444
34 CHROMOSOME 15 880 1.861e-05 0.0003197
35 CELL CORTEX 8 238 1.926e-05 0.0003213
36 CELL BODY 11 494 2.484e-05 0.000403
37 CELL PROJECTION 22 1786 2.987e-05 0.0004715
38 ENDOCYTIC VESICLE 8 256 3.243e-05 0.0004867
39 AXON 10 418 3.25e-05 0.0004867
40 PLASMA MEMBRANE REGION 15 929 3.488e-05 0.0005092
41 NUCLEAR CHROMOSOME 11 523 4.177e-05 0.000595
42 MICROTUBULE CYTOSKELETON 16 1068 4.586e-05 0.0006377
43 EXTRINSIC COMPONENT OF PLASMA MEMBRANE 6 136 4.969e-05 0.0006748
44 PLASMA MEMBRANE RAFT 5 86 5.876e-05 0.0007799
45 SYNAPSE 13 754 6.318e-05 0.0008199
46 BASOLATERAL PLASMA MEMBRANE 7 211 7.092e-05 0.0009004
47 CYTOPLASMIC REGION 8 287 7.257e-05 0.0009017
48 IONOTROPIC GLUTAMATE RECEPTOR COMPLEX 4 47 7.59e-05 0.0009234
49 NUCLEAR CHROMATIN 8 291 7.991e-05 0.0009524
50 ENDOCYTIC VESICLE MEMBRANE 6 152 9.216e-05 0.001076
51 RNA POLYMERASE II TRANSCRIPTION FACTOR COMPLEX 5 101 0.0001263 0.001446
52 PLATELET ALPHA GRANULE LUMEN 4 55 0.0001409 0.001583
53 CELL PROJECTION PART 14 946 0.0001639 0.001741
54 CYTOPLASMIC MICROTUBULE 4 57 0.000162 0.001741
55 SYNAPSE PART 11 610 0.0001637 0.001741
56 LAMELLIPODIUM 6 172 0.0001813 0.001891
57 CHROMATIN 9 441 0.0002705 0.002723
58 CLATHRIN COATED ENDOCYTIC VESICLE 4 65 0.0002697 0.002723
59 NUCLEAR TRANSCRIPTION FACTOR COMPLEX 5 127 0.0003675 0.003637
60 CYTOSKELETAL PART 17 1436 0.0004458 0.004339
61 PLATELET ALPHA GRANULE 4 75 0.0004668 0.004469
62 SECRETORY GRANULE LUMEN 4 85 0.0007497 0.006949
63 DENDRITIC SHAFT 3 37 0.0007398 0.006949
64 MICROTUBULE ORGANIZING CENTER 10 623 0.0008139 0.007426
65 GOLGI LUMEN 4 94 0.001093 0.009817

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04390_Hippo_signaling_pathway 96 154 2.085e-220 3.753e-218
2 hsa04310_Wnt_signaling_pathway 34 151 9.742e-49 8.768e-47
3 hsa04916_Melanogenesis 24 101 7.839e-35 4.703e-33
4 hsa04350_TGF.beta_signaling_pathway 19 85 4.387e-27 1.974e-25
5 hsa04340_Hedgehog_signaling_pathway 15 56 7.296e-23 2.627e-21
6 hsa04520_Adherens_junction 13 73 2.107e-17 6.321e-16
7 hsa04110_Cell_cycle 13 128 4.179e-14 1.075e-12
8 hsa04530_Tight_junction 11 133 4.036e-11 9.081e-10
9 hsa04114_Oocyte_meiosis 9 114 3.951e-09 7.903e-08
10 hsa04151_PI3K_AKT_signaling_pathway 13 351 1.306e-08 2.351e-07
11 hsa04144_Endocytosis 10 203 4.913e-08 8.039e-07
12 hsa04722_Neurotrophin_signaling_pathway 7 127 2.63e-06 3.944e-05
13 hsa04010_MAPK_signaling_pathway 8 268 4.487e-05 0.0006213
14 hsa04510_Focal_adhesion 7 200 5.06e-05 0.0006506
15 hsa04810_Regulation_of_actin_cytoskeleton 7 214 7.749e-05 0.0009299
16 hsa03015_mRNA_surveillance_pathway 4 83 0.0006854 0.00771
17 hsa04670_Leukocyte_transendothelial_migration 4 117 0.002443 0.02586
18 hsa04380_Osteoclast_differentiation 4 128 0.003377 0.03377
19 hsa04910_Insulin_signaling_pathway 4 138 0.004416 0.04019
20 hsa04115_p53_signaling_pathway 3 69 0.004466 0.04019
21 hsa04330_Notch_signaling_pathway 2 47 0.02143 0.1836
22 hsa04720_Long.term_potentiation 2 70 0.0446 0.3649
23 hsa04012_ErbB_signaling_pathway 2 87 0.06559 0.5133
24 hsa04660_T_cell_receptor_signaling_pathway 2 108 0.09507 0.713
25 hsa04270_Vascular_smooth_muscle_contraction 2 116 0.1071 0.7417
26 hsa04514_Cell_adhesion_molecules_.CAMs. 2 136 0.1389 0.9245
27 hsa04120_Ubiquitin_mediated_proteolysis 2 139 0.1438 0.9245
28 hsa04630_Jak.STAT_signaling_pathway 2 155 0.1707 1
29 hsa04145_Phagosome 2 156 0.1724 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

EMX2OS

 hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-18b-5p;hsa-miR-222-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-374a-3p;hsa-miR-484;hsa-miR-532-3p;hsa-miR-550a-5p;hsa-miR-576-5p;hsa-miR-625-5p;hsa-miR-629-5p;hsa-miR-7-5p;hsa-miR-760 16 FGF1 Sponge network 1.057 0.31716 0.817 0.03603 0.558
2

CECR7

 hsa-miR-1304-5p;hsa-miR-16-2-3p;hsa-miR-18a-5p;hsa-miR-18b-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-26b-3p;hsa-miR-26b-5p;hsa-miR-375;hsa-miR-590-3p;hsa-miR-7-1-3p 11 CTGF Sponge network 0.551 0.56177 0.322 0.8416 0.553
3

EMX2OS

 hsa-let-7d-5p;hsa-let-7g-5p;hsa-miR-141-3p;hsa-miR-141-5p;hsa-miR-148a-3p;hsa-miR-200b-3p;hsa-miR-23a-5p;hsa-miR-30d-3p;hsa-miR-324-5p;hsa-miR-339-5p;hsa-miR-532-3p;hsa-miR-589-3p;hsa-miR-590-3p 13 GDF6 Sponge network 1.057 0.31716 0.615 0.4489 0.552
4

CECR7

 hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148a-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-375;hsa-miR-429;hsa-miR-454-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-93-5p 31 FRMD6 Sponge network 0.551 0.56177 0.399 0.6467 0.529
5

CECR7

 hsa-miR-141-3p;hsa-miR-15b-3p;hsa-miR-182-5p;hsa-miR-200a-3p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-33a-3p;hsa-miR-491-5p;hsa-miR-501-3p;hsa-miR-502-3p 12 GLI2 Sponge network 0.551 0.56177 0.224 0.69133 0.52
6

EMX2OS

 hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-146a-5p;hsa-miR-148a-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-27a-3p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-374b-5p;hsa-miR-375;hsa-miR-454-3p;hsa-miR-550a-3p;hsa-miR-590-3p;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-93-5p 30 FRMD6 Sponge network 1.057 0.31716 0.399 0.6467 0.518
7

EMX2OS

 hsa-miR-1304-5p;hsa-miR-16-2-3p;hsa-miR-18a-5p;hsa-miR-18b-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-26b-3p;hsa-miR-26b-5p;hsa-miR-375;hsa-miR-577;hsa-miR-590-3p;hsa-miR-7-1-3p 12 CTGF Sponge network 1.057 0.31716 0.322 0.8416 0.517
8

EMX2OS

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-185-3p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-30b-3p;hsa-miR-30d-3p;hsa-miR-362-3p;hsa-miR-505-5p;hsa-miR-590-3p;hsa-miR-93-5p 17 TCF7L1 Sponge network 1.057 0.31716 0.403 0.47966 0.509
9

MEG3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1304-5p;hsa-miR-141-3p;hsa-miR-148b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-192-3p;hsa-miR-194-5p;hsa-miR-200a-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-221-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-335-5p;hsa-miR-425-5p;hsa-miR-582-3p;hsa-miR-625-5p;hsa-miR-92a-1-5p;hsa-miR-939-5p 24 WTIP Sponge network 0.433 0.33816 0.4 0.40814 0.504
10

EMX2OS

 hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-let-7g-3p;hsa-let-7g-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-10a-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-192-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-27a-3p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-32-5p;hsa-miR-324-3p;hsa-miR-33a-3p;hsa-miR-375;hsa-miR-424-5p;hsa-miR-452-5p;hsa-miR-454-3p;hsa-miR-484;hsa-miR-505-5p;hsa-miR-576-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-7-1-3p;hsa-miR-92a-3p;hsa-miR-940 41 FZD4 Sponge network 1.057 0.31716 0.088 0.9264 0.501
11

CECR7

 hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-let-7g-3p;hsa-let-7g-5p;hsa-miR-106b-5p;hsa-miR-10a-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-192-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-24-3p;hsa-miR-25-3p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-324-3p;hsa-miR-33a-3p;hsa-miR-361-5p;hsa-miR-375;hsa-miR-429;hsa-miR-454-3p;hsa-miR-505-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-7-1-3p 36 FZD4 Sponge network 0.551 0.56177 0.088 0.9264 0.486
12

CECR7

 hsa-miR-148b-3p;hsa-miR-182-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-375;hsa-miR-429;hsa-miR-532-5p;hsa-miR-590-3p 10 SNAI2 Sponge network 0.551 0.56177 0.205 0.75191 0.482
13

EMX2OS

 hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-17-3p;hsa-miR-18a-5p;hsa-miR-1976;hsa-miR-200a-3p;hsa-miR-224-3p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-33b-5p;hsa-miR-374b-5p;hsa-miR-576-5p;hsa-miR-582-3p;hsa-miR-590-3p;hsa-miR-624-5p;hsa-miR-627-5p;hsa-miR-7-1-3p;hsa-miR-93-3p 22 WWTR1 Sponge network 1.057 0.31716 0.125 0.8652 0.482
14

CECR7

 hsa-miR-1275;hsa-miR-16-1-3p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-18b-5p;hsa-miR-222-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-361-5p;hsa-miR-429;hsa-miR-532-3p;hsa-miR-550a-5p;hsa-miR-590-5p;hsa-miR-625-5p;hsa-miR-629-5p;hsa-miR-760 16 FGF1 Sponge network 0.551 0.56177 0.817 0.03603 0.477
15

CECR7

 hsa-let-7d-5p;hsa-let-7g-5p;hsa-miR-1275;hsa-miR-141-3p;hsa-miR-141-5p;hsa-miR-148a-3p;hsa-miR-200b-3p;hsa-miR-429;hsa-miR-532-3p;hsa-miR-589-3p;hsa-miR-590-3p 11 GDF6 Sponge network 0.551 0.56177 0.615 0.4489 0.475
16

CECR7

 hsa-miR-103a-3p;hsa-miR-130b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-188-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-25-3p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-32-3p;hsa-miR-33a-3p;hsa-miR-361-5p;hsa-miR-362-3p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-93-5p 18 LATS2 Sponge network 0.551 0.56177 0.511 0.59675 0.472
17

CECR7

 hsa-let-7f-2-3p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-17-3p;hsa-miR-18a-5p;hsa-miR-200a-3p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-33b-5p;hsa-miR-582-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-627-5p;hsa-miR-651-5p;hsa-miR-7-1-3p 22 WWTR1 Sponge network 0.551 0.56177 0.125 0.8652 0.472
18

MEG3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-146a-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-335-3p;hsa-miR-429;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-93-5p 19 FRMD6 Sponge network 0.433 0.33816 0.399 0.6467 0.46
19

CECR7

 hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1262;hsa-miR-1304-5p;hsa-miR-135b-5p;hsa-miR-141-3p;hsa-miR-148b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-192-3p;hsa-miR-194-5p;hsa-miR-197-3p;hsa-miR-200a-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-221-5p;hsa-miR-25-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-324-3p;hsa-miR-331-3p;hsa-miR-335-5p;hsa-miR-33b-5p;hsa-miR-362-3p;hsa-miR-362-5p;hsa-miR-425-5p;hsa-miR-502-5p;hsa-miR-550a-5p;hsa-miR-582-3p;hsa-miR-625-5p;hsa-miR-760;hsa-miR-769-3p;hsa-miR-92a-1-5p;hsa-miR-939-5p 40 WTIP Sponge network 0.551 0.56177 0.4 0.40814 0.458
20

CECR7

 hsa-let-7g-3p;hsa-miR-106a-5p;hsa-miR-130b-5p;hsa-miR-135b-5p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-24-3p;hsa-miR-25-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-33a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-361-5p;hsa-miR-429;hsa-miR-505-5p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-592;hsa-miR-7-1-3p;hsa-miR-769-3p 38 DLG2 Sponge network 0.551 0.56177 0.164 0.8004 0.452
21

CECR7

 hsa-miR-148a-3p;hsa-miR-148a-5p;hsa-miR-301a-3p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-425-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-942-5p 10 SERPINE1 Sponge network 0.551 0.56177 0.967 0.43183 0.452
22

EMX2OS

 hsa-miR-146a-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-192-5p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-335-5p;hsa-miR-577;hsa-miR-590-3p;hsa-miR-93-3p 12 FZD1 Sponge network 1.057 0.31716 -0.051 0.95908 0.447
23

CECR7

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-362-3p;hsa-miR-429;hsa-miR-505-5p;hsa-miR-590-3p;hsa-miR-93-5p 15 TCF7L1 Sponge network 0.551 0.56177 0.403 0.47966 0.437
24

EMX2OS

 hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1262;hsa-miR-1304-5p;hsa-miR-135b-5p;hsa-miR-141-3p;hsa-miR-148b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-183-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-192-3p;hsa-miR-194-5p;hsa-miR-197-3p;hsa-miR-200a-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-221-5p;hsa-miR-25-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-32-5p;hsa-miR-324-3p;hsa-miR-324-5p;hsa-miR-331-3p;hsa-miR-335-5p;hsa-miR-33b-5p;hsa-miR-362-3p;hsa-miR-425-5p;hsa-miR-484;hsa-miR-502-5p;hsa-miR-550a-5p;hsa-miR-582-3p;hsa-miR-625-5p;hsa-miR-7-5p;hsa-miR-760;hsa-miR-769-3p;hsa-miR-92a-3p;hsa-miR-939-5p 44 WTIP Sponge network 1.057 0.31716 0.4 0.40814 0.432
25

EMX2OS

 hsa-let-7g-3p;hsa-miR-106a-5p;hsa-miR-130b-5p;hsa-miR-135b-5p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-153-3p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-224-3p;hsa-miR-25-3p;hsa-miR-27a-5p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-30b-3p;hsa-miR-30d-3p;hsa-miR-32-3p;hsa-miR-32-5p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-33a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-374b-3p;hsa-miR-374b-5p;hsa-miR-378a-5p;hsa-miR-421;hsa-miR-484;hsa-miR-505-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-592;hsa-miR-642a-5p;hsa-miR-7-1-3p;hsa-miR-769-3p;hsa-miR-877-5p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-940 48 DLG2 Sponge network 1.057 0.31716 0.164 0.8004 0.424
26

EMX2OS

 hsa-miR-103a-3p;hsa-miR-130b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-188-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-25-3p;hsa-miR-27a-3p;hsa-miR-32-3p;hsa-miR-32-5p;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-374b-5p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-5p 18 LATS2 Sponge network 1.057 0.31716 0.511 0.59675 0.418
27

MEG3

 hsa-let-7f-5p;hsa-let-7g-5p;hsa-miR-106b-5p;hsa-miR-10a-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-192-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-429;hsa-miR-576-5p;hsa-miR-590-5p;hsa-miR-7-1-3p 19 FZD4 Sponge network 0.433 0.33816 0.088 0.9264 0.417
28

HCG11

 hsa-miR-128-3p;hsa-miR-130b-3p;hsa-miR-142-5p;hsa-miR-148a-5p;hsa-miR-148b-3p;hsa-miR-16-2-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-215-5p;hsa-miR-26a-1-3p;hsa-miR-33a-3p;hsa-miR-378a-5p;hsa-miR-590-3p;hsa-miR-625-3p;hsa-miR-7-1-3p;hsa-miR-877-5p 16 BMPR2 Sponge network 0.419 0.63279 0.176 0.9 0.414
29

EMX2OS

 hsa-let-7a-3p;hsa-miR-130b-3p;hsa-miR-144-3p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-26b-5p;hsa-miR-29a-5p;hsa-miR-301a-3p;hsa-miR-331-3p;hsa-miR-339-5p;hsa-miR-362-3p;hsa-miR-374b-5p;hsa-miR-421;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-7-1-3p 17 BMPR1B Sponge network 1.057 0.31716 0.028 0.96601 0.41
30

MEG3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-30b-3p;hsa-miR-30d-3p;hsa-miR-429;hsa-miR-93-5p 13 TCF7L1 Sponge network 0.433 0.33816 0.403 0.47966 0.398
31

MIAT

 hsa-miR-106b-5p;hsa-miR-10a-5p;hsa-miR-141-3p;hsa-miR-192-5p;hsa-miR-200c-3p;hsa-miR-24-3p;hsa-miR-301a-3p;hsa-miR-454-3p;hsa-miR-92a-3p;hsa-miR-98-5p 10 FZD4 Sponge network -0.118 0.86338 0.088 0.9264 0.397
32

EMX2OS

 hsa-miR-148a-3p;hsa-miR-148a-5p;hsa-miR-301a-3p;hsa-miR-378a-5p;hsa-miR-421;hsa-miR-425-5p;hsa-miR-452-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-942-5p 10 SERPINE1 Sponge network 1.057 0.31716 0.967 0.43183 0.395
33

EMX2OS

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-301a-3p;hsa-miR-454-3p;hsa-miR-590-3p;hsa-miR-93-3p;hsa-miR-93-5p 10 PARD6G Sponge network 1.057 0.31716 0.117 0.78883 0.393
34

CECR7

 hsa-miR-1275;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-192-5p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-335-5p;hsa-miR-590-3p 10 FZD1 Sponge network 0.551 0.56177 -0.051 0.95908 0.388
35

CECR7

 hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-331-3p;hsa-miR-335-5p;hsa-miR-532-3p;hsa-miR-589-3p 11 WNT9A Sponge network 0.551 0.56177 -0.153 0.81191 0.363
36

EMX2OS

 hsa-let-7a-3p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-186-5p;hsa-miR-200a-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-324-5p;hsa-miR-331-5p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-374b-5p;hsa-miR-375;hsa-miR-454-3p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-7-5p 23 TGFB2 Sponge network 1.057 0.31716 0.567 0.30298 0.36
37

EMX2OS

 hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-185-3p;hsa-miR-32-5p;hsa-miR-331-3p;hsa-miR-335-5p;hsa-miR-424-5p;hsa-miR-532-3p;hsa-miR-589-3p 14 WNT9A Sponge network 1.057 0.31716 -0.153 0.81191 0.357
38

EMX2OS

 hsa-let-7d-5p;hsa-let-7g-5p;hsa-miR-128-3p;hsa-miR-130b-3p;hsa-miR-144-3p;hsa-miR-16-2-3p;hsa-miR-186-5p;hsa-miR-200b-3p;hsa-miR-27a-3p;hsa-miR-32-3p;hsa-miR-331-3p;hsa-miR-339-5p;hsa-miR-374b-5p;hsa-miR-452-3p;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-577;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-7-1-3p 20 TGFBR1 Sponge network 1.057 0.31716 0.001 0.99924 0.345
39

MEG3

 hsa-miR-106a-5p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-153-3p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-30b-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-374b-3p;hsa-miR-429;hsa-miR-576-5p;hsa-miR-590-5p;hsa-miR-7-1-3p 24 DLG2 Sponge network 0.433 0.33816 0.164 0.8004 0.343
40

ZNF883

 hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1227-3p;hsa-miR-1304-5p;hsa-miR-135b-5p;hsa-miR-148b-5p;hsa-miR-17-3p;hsa-miR-183-5p;hsa-miR-186-5p;hsa-miR-194-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-320c;hsa-miR-582-3p 19 WTIP Sponge network 0.913 0.16772 0.4 0.40814 0.343
41

CECR7

 hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-let-7f-2-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-130b-3p;hsa-miR-148a-3p;hsa-miR-148a-5p;hsa-miR-148b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-192-3p;hsa-miR-192-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200b-3p;hsa-miR-200b-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-215-5p;hsa-miR-25-3p;hsa-miR-26a-1-3p;hsa-miR-26a-2-3p;hsa-miR-26b-5p;hsa-miR-29a-5p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-362-3p;hsa-miR-375;hsa-miR-429;hsa-miR-454-3p;hsa-miR-532-5p;hsa-miR-582-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-5p;hsa-miR-651-5p;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-93-5p 48 BMPR2 Sponge network 0.551 0.56177 0.176 0.9 0.34
42

CECR7

 hsa-let-7a-3p;hsa-miR-130b-3p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-26b-5p;hsa-miR-29a-5p;hsa-miR-301a-3p;hsa-miR-331-3p;hsa-miR-362-3p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-7-1-3p 13 BMPR1B Sponge network 0.551 0.56177 0.028 0.96601 0.336
43

MEG3

 hsa-miR-146a-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-192-5p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-335-5p;hsa-miR-577 10 FZD1 Sponge network 0.433 0.33816 -0.051 0.95908 0.335
44

EMX2OS

 hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-130b-3p;hsa-miR-148a-3p;hsa-miR-148a-5p;hsa-miR-148b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-192-3p;hsa-miR-192-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200b-3p;hsa-miR-200b-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-215-5p;hsa-miR-25-3p;hsa-miR-26a-1-3p;hsa-miR-26a-2-3p;hsa-miR-26b-5p;hsa-miR-29a-5p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-32-5p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-362-3p;hsa-miR-375;hsa-miR-378a-5p;hsa-miR-454-3p;hsa-miR-577;hsa-miR-582-3p;hsa-miR-584-5p;hsa-miR-590-3p;hsa-miR-629-5p;hsa-miR-671-5p;hsa-miR-7-1-3p;hsa-miR-7-5p;hsa-miR-877-5p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-93-5p 50 BMPR2 Sponge network 1.057 0.31716 0.176 0.9 0.328
45

ZNF883

 hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-146a-5p;hsa-miR-148a-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-301a-3p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-582-5p 17 FRMD6 Sponge network 0.913 0.16772 0.399 0.6467 0.316
46

MEG3

 hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-186-5p;hsa-miR-200a-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-429;hsa-miR-590-5p 12 TGFB2 Sponge network 0.433 0.33816 0.567 0.30298 0.282
47

MEG3

 hsa-miR-141-3p;hsa-miR-200a-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-576-5p;hsa-miR-582-3p;hsa-miR-627-5p;hsa-miR-7-1-3p 10 WWTR1 Sponge network 0.433 0.33816 0.125 0.8652 0.279
48

CECR7

 hsa-let-7a-3p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-186-5p;hsa-miR-200a-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-331-5p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-362-5p;hsa-miR-375;hsa-miR-429;hsa-miR-454-3p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p 23 TGFB2 Sponge network 0.551 0.56177 0.567 0.30298 0.267
49

DGCR5

 hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-186-5p;hsa-miR-192-3p;hsa-miR-194-5p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-425-5p;hsa-miR-484;hsa-miR-92a-1-5p 10 WTIP Sponge network 0.256 0.70355 0.4 0.40814 0.263
50

ZNF883

 hsa-let-7g-3p;hsa-miR-106a-5p;hsa-miR-130b-5p;hsa-miR-135b-5p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-153-3p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-576-5p;hsa-miR-582-5p;hsa-miR-590-5p 27 DLG2 Sponge network 0.913 0.16772 0.164 0.8004 0.26
51

EMX2OS

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-26b-5p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-671-5p;hsa-miR-93-5p 12 SMAD7 Sponge network 1.057 0.31716 -0.013 0.99011 0.258
52

HCG11

 hsa-let-7g-3p;hsa-miR-130b-5p;hsa-miR-142-3p;hsa-miR-148b-3p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-33a-3p;hsa-miR-378a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-642a-5p;hsa-miR-7-1-3p;hsa-miR-877-5p 15 DLG2 Sponge network 0.419 0.63279 0.164 0.8004 0.255
53

CECR7

 hsa-miR-103a-3p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-151a-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-192-5p;hsa-miR-194-5p;hsa-miR-19a-3p;hsa-miR-200a-3p;hsa-miR-200a-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-425-5p;hsa-miR-429;hsa-miR-532-5p;hsa-miR-582-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-629-5p;hsa-miR-7-1-3p;hsa-miR-93-5p 35 TEAD1 Sponge network 0.551 0.56177 0.022 0.98751 0.252

Quest ID: 7d8859f03cc17d5b25c6efb8bb3a14ae