Explanation
This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are
presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.
"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.
miRNA-gene regulations
| Num | microRNA | Gene | miRNA log2FC | miRNA pvalue | Gene log2FC | Gene pvalue | Interaction | Correlation beta | Correlation P-value | PMID | Reported in cancer studies |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | hsa-miR-125a-5p | ATM | -0.08 | 0.32544 | -0.04 | 0.43965 | miRanda | -0.19 | 0 | NA | |
| 2 | hsa-miR-146b-5p | ATM | 0.44 | 0.00024 | -0.04 | 0.43965 | miRanda | -0.14 | 0 | 27602131 | The role of microRNA 146b miR-146b in ATC remains to be elucidated; In order to characterize the role of miR-146b in ATC overexpression or interference of miR-146b was induced in ATC cell lines and cell proliferation and migration were evaluated; The potential targets of miR-146b were searched in the Gene Expression Omnibus database for ATC and matched non-tumor control samples; The expression level of potential targets was detected following overexpression or interference of miR-146b in ATC cell lines; In addition cell migration of ATC was also affected by miR-146b; During the search for potential targets of miR-146b in ATC p21 also known as p21Waf1/Cip1 or CDKN1A was noted for its role in cell cycle progression and tumor pathogenesis; In conclusion p21 may participate in the regulation of ATC cell proliferation by miR-146b |
| 3 | hsa-miR-186-5p | ATM | 0.06 | 0.51422 | -0.04 | 0.43965 | mirMAP | -0.12 | 0 | NA | |
| 4 | hsa-miR-18a-5p | ATM | 0.18 | 0.07325 | -0.04 | 0.43965 | miRNAWalker2 validate; miRTarBase; MirTarget | -0.1 | 0 | 23437304; 25963391; 23857602; 23229340 | MicroRNA 18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer; Through in silico search the 3'UTR of Ataxia telangiectasia mutated ATM contains a conserved miR-18a binding site; Expression of ATM was down-regulated in CRC tumors p<0.0001 and inversely correlated with miR-18a expression r = -0.4562 p<0.01; This was further confirmed by the down-regulation of ATM protein by miR-18a; As ATM is a key enzyme in DNA damage repair we evaluated the effect of miR-18a on DNA double-strand breaks; miR-18a attenuates cellular repair of DNA double-strand breaks by directly suppressing ATM a key enzyme in DNA damage repair;However the upregulation of miR-18a suppressed the level of ataxia-telangiectasia mutated and attenuated DNA double-strand break repair after irradiation which re-sensitized the cervical cancer cells to radiotherapy by promoting apoptosis;Furthermore we used antisense oligonucleotides against micro RNAs miRNA or miRNA overexpression plasmids to study the role of miR-18a and -106a on ATM expression; Furthermore we identified that ERα activates miR-18a and -106a to downregulate ATM expression; We reveal a novel mechanism involving ERα and miR-18a and -106a regulation of ATM in breast cancer;MicroRNA 18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells; Previous studies showed that certain microRNAs including miR-18a potentially regulate ATM in cancer cells; However the mechanisms behind the modulation of ATM by miR-18a remain to be elucidated in colon cancer cells; In the present study we explored the impact of miR-18a on the autophagy process and ATM expression in HCT116 colon cancer cells; Western blotting and luciferase assays were implemented to explore the impact of miR-18a on ATM gene expression in HCT116 cells; Moreover miR-18a overexpression led to the upregulation of ATM expression and suppression of mTORC1 activity; Results of the present study pertaining to the role of miR-18a in regulating autophagy and ATM gene expression in colon cancer cells revealed a novel function for miR-18a in a critical cellular event and on a crucial gene with significant impacts in cancer development progression treatment and in other diseases |
| 5 | hsa-miR-26b-5p | ATM | -0.1 | 0.2318 | -0.04 | 0.43965 | MirTarget | -0.12 | 4.0E-5 | NA | |
| 6 | hsa-miR-30b-5p | ATM | -0.09 | 0.26324 | -0.04 | 0.43965 | mirMAP | -0.15 | 1.0E-5 | 25202329 | However specific miRNAs are downregulated in ATC such as those of the miR-200 and miR-30 families which are important negative regulators of cell migration invasion and epithelial-to-mesenchymal transition EMT processes that are overactivated in ATC |
| 7 | hsa-miR-30c-5p | ATM | -0.05 | 0.56593 | -0.04 | 0.43965 | mirMAP | -0.21 | 0 | NA | |
| 8 | hsa-miR-30d-3p | ATM | 0.09 | 0.20691 | -0.04 | 0.43965 | mirMAP | -0.11 | 0.00045 | 24345332 | miR-30d has been observed to be significantly down-regulated in human anaplastic thyroid carcinoma ATC and is believed to be an important event in thyroid cell transformation; In this study we found that miR-30d has a critical role in modulating sensitivity of ATC cells to cisplatin a commonly used chemotherapeutic drug for treatment of this neoplasm; Using a mimic of miR-30d we demonstrated that miR-30d could negatively regulate the expression of beclin 1 a key autophagy gene leading to suppression of the cisplatin-activated autophagic response that protects ATC cells from apoptosis; We further showed that inhibition of the beclin 1-mediated autophagy by the miR-30d mimic sensitized ATC cells to cisplatin both in vitro cell culture and in vivo animal xenograft model; These results suggest that dysregulation of miR-30d in ATC cells is responsible for the insensitivity to cisplatin by promoting autophagic survival; Thus miR-30d may be exploited as a potential target for therapeutic intervention in the treatment of ATC |
| 9 | hsa-miR-30d-5p | ATM | -0.06 | 0.47141 | -0.04 | 0.43965 | mirMAP | -0.13 | 0.00075 | 24345332 | miR-30d has been observed to be significantly down-regulated in human anaplastic thyroid carcinoma ATC and is believed to be an important event in thyroid cell transformation; In this study we found that miR-30d has a critical role in modulating sensitivity of ATC cells to cisplatin a commonly used chemotherapeutic drug for treatment of this neoplasm; Using a mimic of miR-30d we demonstrated that miR-30d could negatively regulate the expression of beclin 1 a key autophagy gene leading to suppression of the cisplatin-activated autophagic response that protects ATC cells from apoptosis; We further showed that inhibition of the beclin 1-mediated autophagy by the miR-30d mimic sensitized ATC cells to cisplatin both in vitro cell culture and in vivo animal xenograft model; These results suggest that dysregulation of miR-30d in ATC cells is responsible for the insensitivity to cisplatin by promoting autophagic survival; Thus miR-30d may be exploited as a potential target for therapeutic intervention in the treatment of ATC |
| 10 | hsa-miR-324-5p | ATM | 0.02 | 0.843 | -0.04 | 0.43965 | miRanda | -0.14 | 0 | NA | |
| 11 | hsa-miR-339-5p | ATM | 0.27 | 0.01853 | -0.04 | 0.43965 | miRanda | -0.11 | 0 | NA | |
| 12 | hsa-miR-500a-5p | ATM | 0.06 | 0.39607 | -0.04 | 0.43965 | mirMAP | -0.13 | 0 | NA | |
| 13 | hsa-miR-766-3p | ATM | -0.15 | 0.26666 | -0.04 | 0.43965 | MirTarget | -0.1 | 0 | NA | |
| 14 | hsa-miR-346 | BAX | -0.58 | 0 | 0.35 | 0 | PITA; miRanda; miRNATAP | -0.17 | 0 | NA | |
| 15 | hsa-miR-504-5p | BAX | -0.51 | 6.0E-5 | 0.35 | 0 | miRNAWalker2 validate | -0.17 | 0 | NA | |
| 16 | hsa-miR-140-5p | BID | 0.07 | 0.38045 | -0.3 | 2.0E-5 | miRanda | -0.23 | 0 | NA | |
| 17 | hsa-miR-142-3p | BID | 0.56 | 1.0E-5 | -0.3 | 2.0E-5 | MirTarget; miRanda | -0.21 | 0 | NA | |
| 18 | hsa-miR-149-5p | BID | -0.05 | 0.65771 | -0.3 | 2.0E-5 | miRNAWalker2 validate | -0.18 | 0 | NA | |
| 19 | hsa-miR-17-5p | BID | 0.1 | 0.20621 | -0.3 | 2.0E-5 | TargetScan | -0.15 | 0.00057 | NA | |
| 20 | hsa-miR-199a-5p | BID | 0.17 | 0.09 | -0.3 | 2.0E-5 | miRanda | -0.18 | 0 | NA | |
| 21 | hsa-miR-199b-5p | BID | 0.44 | 0.002 | -0.3 | 2.0E-5 | miRanda | -0.17 | 0 | NA | |
| 22 | hsa-miR-335-3p | BID | 0.35 | 0.00044 | -0.3 | 2.0E-5 | MirTarget | -0.19 | 0 | NA | |
| 23 | hsa-miR-543 | BID | -0.35 | 0.01574 | -0.3 | 2.0E-5 | miRanda | -0.11 | 0 | NA | |
| 24 | hsa-let-7g-5p | CASP3 | -0.03 | 0.74256 | 0.26 | 0 | MirTarget; miRNATAP | -0.13 | 0.00042 | NA | |
| 25 | hsa-miR-101-3p | CASP3 | -0.13 | 0.24189 | 0.26 | 0 | MirTarget | -0.11 | 2.0E-5 | NA | |
| 26 | hsa-miR-128-3p | CASP3 | -0.78 | 0 | 0.26 | 0 | miRNAWalker2 validate | -0.15 | 0 | NA | |
| 27 | hsa-miR-138-5p | CASP3 | -0.62 | 1.0E-5 | 0.26 | 0 | miRNAWalker2 validate; miRTarBase | -0.11 | 0 | NA | |
| 28 | hsa-miR-139-5p | CASP3 | -0.65 | 0 | 0.26 | 0 | miRanda | -0.15 | 0 | NA | |
| 29 | hsa-miR-30d-5p | CASP3 | -0.06 | 0.47141 | 0.26 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.15 | 0.00015 | NA | |
| 30 | hsa-miR-342-3p | CASP3 | -0.13 | 0.10581 | 0.26 | 0 | miRanda | -0.14 | 1.0E-5 | NA | |
| 31 | hsa-miR-374b-5p | CASP3 | -0.21 | 0.00569 | 0.26 | 0 | mirMAP | -0.15 | 0 | NA | |
| 32 | hsa-miR-7-1-3p | CASP3 | -0.09 | 0.37322 | 0.26 | 0 | MirTarget | -0.1 | 0 | NA | |
| 33 | hsa-miR-105-5p | CASP8 | -0.57 | 1.0E-5 | 0.55 | 0 | MirTarget | -0.33 | 0 | NA | |
| 34 | hsa-miR-129-5p | CASP8 | -0.57 | 0.00116 | 0.55 | 0 | miRanda | -0.12 | 0 | NA | |
| 35 | hsa-miR-137 | CASP8 | -0.92 | 0 | 0.55 | 0 | miRanda | -0.13 | 0 | NA | |
| 36 | hsa-miR-490-3p | CASP8 | -0.83 | 1.0E-5 | 0.55 | 0 | miRanda | -0.12 | 0 | NA | |
| 37 | hsa-miR-125a-3p | CASP9 | 0.18 | 0.10623 | -0.19 | 0.00861 | miRanda | -0.11 | 2.0E-5 | NA | |
| 38 | hsa-miR-126-5p | CASP9 | 0.18 | 0.07117 | -0.19 | 0.00861 | MirTarget | -0.26 | 0 | NA | |
| 39 | hsa-miR-133a-3p | CASP9 | -0.34 | 0.01804 | -0.19 | 0.00861 | miRNAWalker2 validate; miRTarBase | -0.13 | 0 | NA | |
| 40 | hsa-miR-140-5p | CASP9 | 0.07 | 0.38045 | -0.19 | 0.00861 | miRanda | -0.2 | 0 | NA | |
| 41 | hsa-miR-15a-5p | CASP9 | 0.14 | 0.05362 | -0.19 | 0.00861 | mirMAP | -0.24 | 0 | NA | |
| 42 | hsa-miR-15b-5p | CASP9 | 0.59 | 0 | -0.19 | 0.00861 | mirMAP | -0.19 | 0 | NA | |
| 43 | hsa-miR-16-5p | CASP9 | 0.25 | 0.00346 | -0.19 | 0.00861 | mirMAP | -0.2 | 0 | NA | |
| 44 | hsa-miR-193b-3p | CASP9 | 0.08 | 0.32472 | -0.19 | 0.00861 | miRNAWalker2 validate | -0.29 | 0 | NA | |
| 45 | hsa-miR-199a-3p | CASP9 | 0.41 | 0.0005 | -0.19 | 0.00861 | mirMAP | -0.2 | 0 | 23319430 | The techniques used were the MTT assay flow cytometry real-time PCR to assess miR-199a expression as also caspase-8 and caspase-9 activity in HepG2 cells treated with Propofol |
| 46 | hsa-miR-199b-3p | CASP9 | 0.41 | 0.00052 | -0.19 | 0.00861 | mirMAP | -0.2 | 0 | NA | |
| 47 | hsa-miR-342-5p | CASP9 | 0.04 | 0.54413 | -0.19 | 0.00861 | MirTarget | -0.17 | 0.00018 | NA | |
| 48 | hsa-miR-424-5p | CASP9 | 0.25 | 0.0071 | -0.19 | 0.00861 | mirMAP | -0.12 | 0.00014 | NA | |
| 49 | hsa-miR-450b-5p | CASP9 | 0.27 | 0.00802 | -0.19 | 0.00861 | mirMAP | -0.11 | 0.00015 | NA | |
| 50 | hsa-miR-495-3p | CASP9 | -0.42 | 0.00504 | -0.19 | 0.00861 | mirMAP | -0.11 | 0 | NA | |
| 51 | hsa-miR-548b-3p | CASP9 | 0.34 | 0.00224 | -0.19 | 0.00861 | MirTarget | -0.13 | 0 | NA | |
| 52 | hsa-miR-590-3p | CASP9 | 0.31 | 0.00048 | -0.19 | 0.00861 | miRanda | -0.11 | 0.00056 | NA | |
| 53 | hsa-miR-139-5p | CCNB1 | -0.65 | 0 | 0.85 | 0 | miRanda | -0.16 | 0 | NA | |
| 54 | hsa-miR-339-5p | CCNB3 | 0.27 | 0.01853 | -0.23 | 0.006 | miRanda | -0.18 | 0 | NA | |
| 55 | hsa-miR-361-5p | CCNB3 | 0.01 | 0.88223 | -0.23 | 0.006 | miRanda | -0.22 | 0.00057 | NA | |
| 56 | hsa-miR-590-3p | CCNB3 | 0.31 | 0.00048 | -0.23 | 0.006 | miRanda | -0.18 | 1.0E-5 | NA | |
| 57 | hsa-let-7e-5p | CCND1 | 0.05 | 0.65726 | 0.52 | 0 | miRTarBase; miRNATAP | -0.23 | 0 | NA | |
| 58 | hsa-let-7i-5p | CCND1 | 0.1 | 0.19212 | 0.52 | 0 | miRNATAP | -0.24 | 0.00183 | NA | |
| 59 | hsa-miR-1266-5p | CCND1 | 0.31 | 0.01387 | 0.52 | 0 | MirTarget | -0.11 | 0.00109 | NA | |
| 60 | hsa-miR-135a-5p | CCND1 | -0.12 | 0.19699 | 0.52 | 0 | mirMAP | -0.25 | 0 | NA | |
| 61 | hsa-miR-23b-3p | CCND1 | 0.05 | 0.63028 | 0.52 | 0 | miRNATAP | -0.28 | 0 | NA | |
| 62 | hsa-miR-26b-5p | CCND1 | -0.1 | 0.2318 | 0.52 | 0 | miRNAWalker2 validate | -0.17 | 0.00692 | NA | |
| 63 | hsa-miR-29a-3p | CCND1 | -0.22 | 0.03495 | 0.52 | 0 | mirMAP | -0.23 | 1.0E-5 | NA | |
| 64 | hsa-miR-29b-3p | CCND1 | -0.18 | 0.08561 | 0.52 | 0 | mirMAP | -0.31 | 0 | NA | |
| 65 | hsa-miR-29c-3p | CCND1 | -0.37 | 0.00203 | 0.52 | 0 | mirMAP | -0.26 | 0 | NA | |
| 66 | hsa-miR-3065-5p | CCND1 | -0.26 | 0.04146 | 0.52 | 0 | mirMAP | -0.11 | 0.00178 | NA | |
| 67 | hsa-miR-330-3p | CCND1 | -0.43 | 0.003 | 0.52 | 0 | mirMAP | -0.16 | 0 | NA | |
| 68 | hsa-miR-338-3p | CCND1 | -0.4 | 0.00344 | 0.52 | 0 | miRNAWalker2 validate; miRTarBase; miRanda | -0.14 | 7.0E-5 | NA | |
| 69 | hsa-miR-34a-5p | CCND1 | 0.14 | 0.21128 | 0.52 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.18 | 0 | 25792709; 21399894 | This inhibition of proliferation was associated with a decrease in cyclin D1 levels orchestrated principally by HNF-4α a target of miR-34a considered to act as a tumour suppressor in the liver;Quantitative PCR and western analysis confirmed decreased expression of two genes BCL-2 and CCND1 in docetaxel-resistant cells which are both targeted by miR-34a |
| 70 | hsa-miR-365a-3p | CCND1 | -0.18 | 0.02927 | 0.52 | 0 | miRNAWalker2 validate; miRTarBase | -0.2 | 0.0002 | NA | |
| 71 | hsa-miR-425-5p | CCND1 | -0.04 | 0.68228 | 0.52 | 0 | miRNAWalker2 validate | -0.13 | 0.00326 | NA | |
| 72 | hsa-miR-490-3p | CCND1 | -0.83 | 1.0E-5 | 0.52 | 0 | miRanda | -0.13 | 0 | 24440705 | MicroRNA 490 3p inhibits proliferation of A549 lung cancer cells by targeting CCND1; We also found that forced expression of miR-490-3P decreased both mRNA and protein levels of CCND1 which plays a key role in G1/S phase transition; In addition the dual-luciferase reporter assays indicated that miR-490-3P directly targets CCND1 through binding its 3'UTR |
| 73 | hsa-miR-495-3p | CCND1 | -0.42 | 0.00504 | 0.52 | 0 | MirTarget | -0.14 | 0 | NA | |
| 74 | hsa-miR-7-1-3p | CCND1 | -0.09 | 0.37322 | 0.52 | 0 | mirMAP | -0.24 | 0 | NA | |
| 75 | hsa-miR-769-3p | CCND1 | -0.29 | 0.01815 | 0.52 | 0 | mirMAP | -0.28 | 0 | NA | |
| 76 | hsa-miR-885-5p | CCND1 | -0.42 | 1.0E-5 | 0.52 | 0 | miRNATAP | -0.29 | 0 | NA | |
| 77 | hsa-let-7b-3p | CCND2 | -0 | 0.95229 | 0.28 | 0.00231 | mirMAP | -0.12 | 0.006 | NA | |
| 78 | hsa-let-7f-1-3p | CCND2 | 0.11 | 0.21485 | 0.28 | 0.00231 | mirMAP | -0.12 | 0.00234 | NA | |
| 79 | hsa-let-7g-5p | CCND2 | -0.03 | 0.74256 | 0.28 | 0.00231 | miRNATAP | -0.2 | 0.0013 | NA | |
| 80 | hsa-let-7i-5p | CCND2 | 0.1 | 0.19212 | 0.28 | 0.00231 | miRNATAP | -0.16 | 0.00989 | NA | |
| 81 | hsa-miR-129-5p | CCND2 | -0.57 | 0.00116 | 0.28 | 0.00231 | mirMAP | -0.11 | 0 | NA | |
| 82 | hsa-miR-145-3p | CCND2 | 0.11 | 0.29415 | 0.28 | 0.00231 | mirMAP | -0.15 | 1.0E-5 | NA | |
| 83 | hsa-miR-145-5p | CCND2 | 0.11 | 0.31003 | 0.28 | 0.00231 | miRNATAP | -0.16 | 1.0E-5 | NA | |
| 84 | hsa-miR-146b-3p | CCND2 | 0.28 | 0.01189 | 0.28 | 0.00231 | MirTarget; PITA; miRNATAP | -0.12 | 0.00028 | NA | |
| 85 | hsa-miR-150-5p | CCND2 | 0.06 | 0.5133 | 0.28 | 0.00231 | mirMAP | -0.15 | 8.0E-5 | NA | |
| 86 | hsa-miR-151a-3p | CCND2 | 0.03 | 0.72683 | 0.28 | 0.00231 | mirMAP | -0.12 | 0.00498 | NA | |
| 87 | hsa-miR-185-5p | CCND2 | -0.08 | 0.40411 | 0.28 | 0.00231 | MirTarget; miRNATAP | -0.18 | 1.0E-5 | NA | |
| 88 | hsa-miR-186-5p | CCND2 | 0.06 | 0.51422 | 0.28 | 0.00231 | mirMAP; miRNATAP | -0.13 | 0.00173 | NA | |
| 89 | hsa-miR-191-5p | CCND2 | 0.1 | 0.22008 | 0.28 | 0.00231 | MirTarget | -0.2 | 0.00024 | NA | |
| 90 | hsa-miR-26a-5p | CCND2 | 0.03 | 0.72661 | 0.28 | 0.00231 | miRNAWalker2 validate; miRTarBase; mirMAP; miRNATAP | -0.12 | 0.0067 | NA | |
| 91 | hsa-miR-26b-5p | CCND2 | -0.1 | 0.2318 | 0.28 | 0.00231 | mirMAP; miRNATAP | -0.22 | 3.0E-5 | NA | |
| 92 | hsa-miR-28-5p | CCND2 | 0.1 | 0.15359 | 0.28 | 0.00231 | miRanda | -0.15 | 0.00459 | NA | |
| 93 | hsa-miR-29a-3p | CCND2 | -0.22 | 0.03495 | 0.28 | 0.00231 | MirTarget; miRNATAP | -0.2 | 1.0E-5 | 22330340; 24130168 | In addition to CCND2 miR-29 also targets E2F7 another cell cycle regulator;We further demonstrated that miR-29 family acted as tumor suppressors through targeting CCND2 and matrix metalloproteinase-2 genes in GC |
| 94 | hsa-miR-29a-5p | CCND2 | -0.07 | 0.35062 | 0.28 | 0.00231 | mirMAP | -0.17 | 0.00069 | 22330340; 24130168 | In addition to CCND2 miR-29 also targets E2F7 another cell cycle regulator;We further demonstrated that miR-29 family acted as tumor suppressors through targeting CCND2 and matrix metalloproteinase-2 genes in GC |
| 95 | hsa-miR-29b-3p | CCND2 | -0.18 | 0.08561 | 0.28 | 0.00231 | MirTarget; miRNATAP | -0.2 | 0 | 22330340; 24130168 | In addition to CCND2 miR-29 also targets E2F7 another cell cycle regulator;We further demonstrated that miR-29 family acted as tumor suppressors through targeting CCND2 and matrix metalloproteinase-2 genes in GC |
| 96 | hsa-miR-29c-3p | CCND2 | -0.37 | 0.00203 | 0.28 | 0.00231 | MirTarget; miRNATAP | -0.24 | 0 | NA | |
| 97 | hsa-miR-30d-3p | CCND2 | 0.09 | 0.20691 | 0.28 | 0.00231 | mirMAP | -0.16 | 0.00383 | NA | |
| 98 | hsa-miR-30e-3p | CCND2 | 0 | 0.98497 | 0.28 | 0.00231 | mirMAP | -0.27 | 0 | NA | |
| 99 | hsa-miR-324-3p | CCND2 | -0.01 | 0.90449 | 0.28 | 0.00231 | miRNAWalker2 validate | -0.18 | 2.0E-5 | NA | |
| 100 | hsa-miR-331-5p | CCND2 | 0.01 | 0.94283 | 0.28 | 0.00231 | miRNATAP | -0.17 | 0.00047 | NA | |
| 101 | hsa-miR-33a-3p | CCND2 | -0.16 | 0.09915 | 0.28 | 0.00231 | MirTarget | -0.1 | 0.00682 | NA | |
| 102 | hsa-miR-3622a-3p | CCND2 | 0.04 | 0.75606 | 0.28 | 0.00231 | mirMAP | -0.13 | 2.0E-5 | NA | |
| 103 | hsa-miR-488-3p | CCND2 | -0.26 | 0.00281 | 0.28 | 0.00231 | mirMAP | -0.18 | 2.0E-5 | NA | |
| 104 | hsa-miR-488-5p | CCND2 | -0.39 | 0 | 0.28 | 0.00231 | mirMAP | -0.15 | 0.00316 | NA | |
| 105 | hsa-miR-500a-5p | CCND2 | 0.06 | 0.39607 | 0.28 | 0.00231 | mirMAP | -0.16 | 0.00132 | NA | |
| 106 | hsa-miR-501-5p | CCND2 | 0.09 | 0.30966 | 0.28 | 0.00231 | PITA; mirMAP; miRNATAP | -0.11 | 0.00802 | NA | |
| 107 | hsa-miR-660-5p | CCND2 | -0.14 | 0.09455 | 0.28 | 0.00231 | mirMAP | -0.24 | 0 | NA | |
| 108 | hsa-miR-7-1-3p | CCND2 | -0.09 | 0.37322 | 0.28 | 0.00231 | mirMAP | -0.15 | 3.0E-5 | NA | |
| 109 | hsa-miR-192-5p | CCNE1 | -0.04 | 0.62162 | 0.25 | 6.0E-5 | miRNAWalker2 validate | -0.13 | 0.00029 | NA | |
| 110 | hsa-miR-195-5p | CCNE1 | -0.01 | 0.9297 | 0.25 | 6.0E-5 | miRNAWalker2 validate; MirTarget; miRNATAP | -0.19 | 0 | 24402230 | Furthermore through qPCR and western blot assays we showed that overexpression of miR-195-5p reduced CCNE1 mRNA and protein levels respectively |
| 111 | hsa-miR-497-5p | CCNE1 | -0 | 0.9917 | 0.25 | 6.0E-5 | MirTarget; miRNATAP | -0.11 | 0.00593 | 24112607; 25909221; 24909281 | Western blot assays confirmed that overexpression of miR-497 reduced cyclin E1 protein levels; Inhibited cellular growth suppressed cellular migration and invasion and G1 cell cycle arrest were observed upon overexpression of miR-497 in cells possibly by targeting cyclin E1;The effect of simultaneous overexpression of miR-497 and miR-34a on the inhibition of cell proliferation colony formation and tumor growth and the downregulation of cyclin E1 was stronger than the effect of each miRNA alone; The synergistic actions of miR-497 and miR-34a partly correlated with cyclin E1 levels; These results indicate cyclin E1 is downregulated by both miR-497 and miR-34a which synergistically retard the growth of human lung cancer cells;miR 497 suppresses proliferation of human cervical carcinoma HeLa cells by targeting cyclin E1; Furthermore the target effect of miR-497 on the CCNE1 was identified by dual-luciferase reporter assay system qRT-PCR and Western blotting; Over-expressed miR-497 in HeLa cells could suppress cell proliferation by targeting CCNE1 |
| 112 | hsa-miR-30a-5p | CCNE2 | -0.06 | 0.51385 | 0.32 | 0.00026 | miRNATAP | -0.4 | 0 | NA | |
| 113 | hsa-miR-30d-5p | CCNE2 | -0.06 | 0.47141 | 0.32 | 0.00026 | miRNATAP | -0.25 | 0.00028 | 25843294 | MicroRNA 30d 5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non small cell lung cancer; In addition the re-introduction of CCNE2 expression antagonised the inhibitory effects of miR-30d-5p on the capacity of NSCLC cells for proliferation and motility |
| 114 | hsa-miR-9-5p | CCNG1 | -0.13 | 0.2699 | 0.09 | 0.05379 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.23 | 0 | 26152689 | CCNG1 validated as a direct target of miR-9 mediates paclitaxel resistance; Methylation-associated miR-9 down-regulation is probably one of the key mechanisms for paclitaxel resistance in EOC cells via targeting CCNG1 |
| 115 | hsa-let-7a-2-3p | CCNG2 | 0.3 | 0.00291 | -0.12 | 0.03505 | MirTarget | -0.1 | 0 | NA | |
| 116 | hsa-miR-135a-5p | CCNG2 | -0.12 | 0.19699 | -0.12 | 0.03505 | MirTarget; miRNATAP | -0.14 | 0 | NA | |
| 117 | hsa-miR-21-5p | CCNG2 | 1.05 | 0 | -0.12 | 0.03505 | mirMAP | -0.13 | 0 | NA | |
| 118 | hsa-miR-26b-5p | CCNG2 | -0.1 | 0.2318 | -0.12 | 0.03505 | mirMAP | -0.15 | 0 | NA | |
| 119 | hsa-miR-28-5p | CCNG2 | 0.1 | 0.15359 | -0.12 | 0.03505 | miRanda | -0.15 | 0 | NA | |
| 120 | hsa-miR-3065-3p | CCNG2 | -0.26 | 0.03438 | -0.12 | 0.03505 | MirTarget; miRNATAP | -0.16 | 0 | NA | |
| 121 | hsa-miR-3065-5p | CCNG2 | -0.26 | 0.04146 | -0.12 | 0.03505 | MirTarget; mirMAP | -0.14 | 0 | NA | |
| 122 | hsa-miR-320c | CCNG2 | 0.34 | 0.00025 | -0.12 | 0.03505 | mirMAP | -0.12 | 0 | NA | |
| 123 | hsa-miR-374a-5p | CCNG2 | 0.01 | 0.86542 | -0.12 | 0.03505 | mirMAP | -0.15 | 1.0E-5 | NA | |
| 124 | hsa-miR-576-5p | CCNG2 | 0.11 | 0.19438 | -0.12 | 0.03505 | mirMAP | -0.17 | 0 | NA | |
| 125 | hsa-miR-590-3p | CCNG2 | 0.31 | 0.00048 | -0.12 | 0.03505 | miRanda; mirMAP | -0.12 | 0 | NA | |
| 126 | hsa-miR-590-5p | CCNG2 | 0.17 | 0.0386 | -0.12 | 0.03505 | mirMAP | -0.11 | 2.0E-5 | NA | |
| 127 | hsa-miR-664a-3p | CCNG2 | 0.04 | 0.61133 | -0.12 | 0.03505 | MirTarget; mirMAP | -0.12 | 1.0E-5 | NA | |
| 128 | hsa-miR-708-3p | CCNG2 | 0 | 0.96246 | -0.12 | 0.03505 | MirTarget | -0.17 | 0 | NA | |
| 129 | hsa-miR-93-5p | CCNG2 | 0.14 | 0.10106 | -0.12 | 0.03505 | miRNAWalker2 validate; MirTarget; miRNATAP | -0.11 | 0.0055 | NA | |
| 130 | hsa-miR-362-3p | CD82 | 0.03 | 0.73647 | -0.1 | 0.17331 | miRanda | -0.1 | 0.00047 | 25652145 | Anti miR 362 3p Inhibits Migration and Invasion of Human Gastric Cancer Cells by Its Target CD82; Next we analyzed the level of miR-362-3p expression and CD82 in different differentiated GC cells compared with a normal gastric mucosa cell by RT-PCR and Western blot; Dual-luciferase reporter assay and Western blot confirmed a direct interaction between miR-362-3p and CD82 3'UTR; After miR-362-3p and CD82 were silenced in GC cells we compared the transfected GC cells migration and invasion capacity by transwell assay; Western blot was used to detect the impact of CD82 and miR-362-3p on epithelial-to-mesenchymal transition markers in treated GC cells; Level of miR-362-3p expression was much higher in GC cells than in normal gastric mucosa cell and miR-362-3p expression negatively correlated with CD82 mRNA expression in these cell lines; Furthermore miR-362-3p expression induced corrected GC cell metastasis capacity by suppression of CD82 expression; This study illuminated that downregulation of miR-362-3p along with the upregulation of CD82 in GC cells resulted in the inhibition of GC migration and invasion; Thus our results suggested that miR-362-3p or CD82 can be exploited as a new potential target for control of GC in the future |
| 131 | hsa-miR-103a-3p | CDK2 | -0.15 | 0.1284 | 0.81 | 0 | miRNAWalker2 validate | -0.24 | 0.0001 | NA | |
| 132 | hsa-miR-124-3p | CDK2 | -0.51 | 0.00781 | 0.81 | 0 | miRNAWalker2 validate; miRTarBase | -0.17 | 0 | NA | |
| 133 | hsa-miR-490-3p | CDK2 | -0.83 | 1.0E-5 | 0.81 | 0 | miRanda | -0.2 | 0 | NA | |
| 134 | hsa-miR-495-3p | CDK2 | -0.42 | 0.00504 | 0.81 | 0 | mirMAP | -0.16 | 0 | NA | |
| 135 | hsa-miR-7-1-3p | CDK2 | -0.09 | 0.37322 | 0.81 | 0 | mirMAP | -0.22 | 0 | NA | |
| 136 | hsa-miR-885-5p | CDK2 | -0.42 | 1.0E-5 | 0.81 | 0 | miRNAWalker2 validate; miRTarBase | -0.32 | 0 | NA | |
| 137 | hsa-miR-124-3p | CDK4 | -0.51 | 0.00781 | 0.45 | 0 | miRNAWalker2 validate; miRTarBase | -0.15 | 0 | 25348738; 25731732; 27323123 | MiR 124 retards bladder cancer growth by directly targeting CDK4; In order to investigate the physiological role of miR-124 in bladder cancer target genes of miR-124 were predicted by the TargetScan software and cyclin-dependent kinase CDK4 which has been implicated as a regulator of cell cycle was chosen for further study; MiR-124 could significantly repress CDK4 expression by targeting its binding site in the 3'UTR of CDK4 in vitro; In both bladder cancer cell lines and tissues the expression of miR-124 was significantly down-regulated while CDK4 expression was up-regulated; And the expression of miR-124 and CDK4 showed an obvious inverse correlation in these xenograft tissues which was also observed in human bladder cancer tissue samples; Taken together our results strongly suggest that miR-124 can arrest cell cycle and restrain the growth of bladder cancer by targeting CDK4 directly;MiR 124 inhibits cell proliferation in breast cancer through downregulation of CDK4; We identified and confirmed that cyclin-dependent kinase 4 CDK4 was a direct target of miR-124; Overexpression of miR-124 suppressed CDK4 protein expression and attenuated cell viability proliferation and cell cycle progression in MCF-7 and MDA-MB-435S breast cancer cells in vitro; Overexpression of CDK4 partially rescued the inhibitory effect of miR-124 in the breast cancer cells; Our results demonstrate that miR-124 functions as a growth-suppressive miRNA and plays an important role in inhibiting tumorigenesis by targeting CDK4;miR 124 radiosensitizes human esophageal cancer cell TE 1 by targeting CDK4; Finally we identified that CDK4 is a direct target of miR-124 in TE-1 cells using target prediction algorithms and a luciferase reporter assay; Moreover western blot assay confirmed that CDK4 was downregulated during miR-124 transfection |
| 138 | hsa-miR-145-5p | CDK4 | 0.11 | 0.31003 | 0.45 | 0 | miRNAWalker2 validate; miRTarBase | -0.18 | 0 | 21092188 | Furthermore we found that CDK4 was regulated by miR-145 in cell cycle control |
| 139 | hsa-miR-24-3p | CDK4 | 0.13 | 0.21296 | 0.45 | 0 | miRNAWalker2 validate; miRTarBase | -0.14 | 6.0E-5 | NA | |
| 140 | hsa-miR-34a-5p | CDK4 | 0.14 | 0.21128 | 0.45 | 0 | miRNAWalker2 validate; miRTarBase | -0.12 | 0.00014 | 25789847 | Real-time PCR and western blot analysis of extracted RNA and total protein revealed artemsinin and artesunate increased miR-34a expression in a dose-dependent manner correlating with down-regulation of the miR-34a target gene CDK4; Phytochemical treatments inhibited the luciferase activity of a construct containing the wild-type 3'UTR of CDK4 but not those with a mutated miR-34a binding site whereas transfection of miR-34a inhibitors ablated the phytochemical mediated down-regulation of CDK4 and induction of cell cycle arrest |
| 141 | hsa-miR-766-3p | CDK4 | -0.15 | 0.26666 | 0.45 | 0 | miRNAWalker2 validate | -0.21 | 0 | NA | |
| 142 | hsa-miR-101-3p | CDK6 | -0.13 | 0.24189 | 0.51 | 1.0E-5 | mirMAP | -0.21 | 0.00012 | NA | |
| 143 | hsa-miR-1179 | CDK6 | -0.12 | 0.31099 | 0.51 | 1.0E-5 | PITA; miRNATAP | -0.14 | 0.00088 | NA | |
| 144 | hsa-miR-1224-5p | CDK6 | -0.54 | 0.00201 | 0.51 | 1.0E-5 | miRNATAP | -0.1 | 0.00024 | NA | |
| 145 | hsa-miR-129-5p | CDK6 | -0.57 | 0.00116 | 0.51 | 1.0E-5 | miRNAWalker2 validate | -0.1 | 0.00025 | 24055727 | Interestingly we showed that cyclin dependent kinase 6 CDK6 a cell cycle-associated protein involved in G1-S transition was a target of miR-129 |
| 146 | hsa-miR-137 | CDK6 | -0.92 | 0 | 0.51 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; PITA; miRNATAP | -0.1 | 5.0E-5 | 18577219; 25342326; 23178712; 21051724 | Transfection of microRNA-124 or microRNA-137 also induced G1 cell cycle arrest in U251 and SF6969 glioblastoma multiforme cells which was associated with decreased expression of cyclin-dependent kinase 6 and phosphorylated retinoblastoma pSer 807/811 proteins;Bioinformatics prediction and luciferase reporter assay revealed CDK6 as a target gene through which miR-137 exerted an inhibitory function;miR 137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6; Ectopic expression of miR-137 in lung cancer cells significantly downregulated Cdc42 Cdk6 and induced G1 cell cycle arrest leading to a significant decrease in cell growth in vivo and in vitro; Further both Cdc42 and Cdk6 were confirmed as targets of miR-137;The results showed that miR-137 can act as a tumor suppressor in uveal melanoma cell proliferation through downregulation of the targets MITF and CDK6 miR-137 may be epigenetically silenced during uveal melanoma tumorigenesis |
| 147 | hsa-miR-140-3p | CDK6 | -0.12 | 0.14797 | 0.51 | 1.0E-5 | miRNATAP | -0.26 | 0.00042 | NA | |
| 148 | hsa-miR-29a-3p | CDK6 | -0.22 | 0.03495 | 0.51 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.3 | 0 | 22493297; 23245396; 20086245 | In addition a target of miR-29a cyclin-dependent kinase 6 gene and a target of miR-142-3p TGF-β-activated kinase 1/MAP3K7 binding protein 2 gene are involved in the regulation of both monocytic and granulocytic differentiation;The IFN-γ-induced G1-arrest of melanoma cells involves down-regulation of CDK6 which we proved to be a direct target of miR-29 in these cells;microRNA expression profile and identification of miR 29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma; Furthermore we demonstrate miR-29 inhibition of CDK6 protein and mRNA levels by direct binding to 3'-untranslated region; Inverse correlation between miR-29 and CDK6 was observed in MCL |
| 149 | hsa-miR-29b-3p | CDK6 | -0.18 | 0.08561 | 0.51 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.27 | 0 | 26180082; 23245396; 25472644; 23591808; 27230400; 20086245 | Knockdown of NTSR1 increased the expression of miR-29b-1 and miR-129-3p which were responsible for the decreased CDK6 expression;The IFN-γ-induced G1-arrest of melanoma cells involves down-regulation of CDK6 which we proved to be a direct target of miR-29 in these cells;Moreover miR-29b inhibited the expression of MCL1 and CDK6;Here we have identified the oncogene cyclin-dependent protein kinase 6 CDK6 as a direct target of miR-29b in lung cancer;MiR 29b suppresses the proliferation and migration of osteosarcoma cells by targeting CDK6; In this study we investigated the role of miR-29b as a novel regulator of CDK6 using bioinformatics methods; We demonstrated that CDK6 can be downregulated by miR-29b via binding to the 3'-UTR region in osteosarcoma cells; Furthermore we identified an inverse correlation between miR-29b and CDK6 protein levels in osteosarcoma tissues; The results revealed that miR-29b acts as a tumor suppressor of osteosarcoma by targeting CDK6 in the proliferation and migration processes;microRNA expression profile and identification of miR 29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma; Furthermore we demonstrate miR-29 inhibition of CDK6 protein and mRNA levels by direct binding to 3'-untranslated region; Inverse correlation between miR-29 and CDK6 was observed in MCL |
| 150 | hsa-miR-29c-3p | CDK6 | -0.37 | 0.00203 | 0.51 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.21 | 0 | 26396669 | Furthermore through qPCR and Western blot assays confirmed that overexpression of miR-29c reduced CDK6 mRNA and protein levels; miR-29c could inhibit the proliferation migration and invasion of bladder cancer cells via regulating CDK6 |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | REGULATION OF CELL CYCLE | 31 | 949 | 7.334e-29 | 3.413e-25 |
| 2 | CELL CYCLE | 30 | 1316 | 3.358e-23 | 7.813e-20 |
| 3 | NEGATIVE REGULATION OF CELL CYCLE | 21 | 433 | 2.588e-22 | 4.014e-19 |
| 4 | REGULATION OF CELL CYCLE ARREST | 14 | 108 | 5.979e-21 | 6.955e-18 |
| 5 | POSITIVE REGULATION OF CELL DEATH | 22 | 605 | 1.04e-20 | 9.68e-18 |
| 6 | REGULATION OF CELL DEATH | 29 | 1472 | 1.57e-20 | 1.217e-17 |
| 7 | CELL CYCLE PROCESS | 26 | 1081 | 2.944e-20 | 1.957e-17 |
| 8 | REGULATION OF MITOTIC CELL CYCLE | 20 | 468 | 3.997e-20 | 2.325e-17 |
| 9 | MITOTIC CELL CYCLE | 23 | 766 | 7.626e-20 | 3.943e-17 |
| 10 | SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE | 13 | 96 | 9.474e-20 | 4.408e-17 |
| 11 | NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION | 13 | 98 | 1.257e-19 | 5.317e-17 |
| 12 | G1 DNA DAMAGE CHECKPOINT | 12 | 73 | 2.352e-19 | 9.122e-17 |
| 13 | REGULATION OF CELL CYCLE G1 S PHASE TRANSITION | 14 | 147 | 5.336e-19 | 1.899e-16 |
| 14 | POSITIVE REGULATION OF CELL CYCLE PROCESS | 16 | 247 | 6.088e-19 | 1.899e-16 |
| 15 | CELL CYCLE CHECKPOINT | 15 | 194 | 6.121e-19 | 1.899e-16 |
| 16 | REGULATION OF CELL CYCLE PHASE TRANSITION | 17 | 321 | 1.244e-18 | 3.617e-16 |
| 17 | CELL DEATH | 24 | 1001 | 1.633e-18 | 4.261e-16 |
| 18 | POSITIVE REGULATION OF CELL CYCLE ARREST | 12 | 85 | 1.648e-18 | 4.261e-16 |
| 19 | POSITIVE REGULATION OF CELL CYCLE | 17 | 332 | 2.199e-18 | 5.385e-16 |
| 20 | NEGATIVE REGULATION OF CELL CYCLE PROCESS | 15 | 214 | 2.721e-18 | 6.33e-16 |
| 21 | SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 13 | 127 | 4.232e-18 | 9.376e-16 |
| 22 | REGULATION OF TRANSFERASE ACTIVITY | 23 | 946 | 8.185e-18 | 1.731e-15 |
| 23 | CELLULAR RESPONSE TO DNA DAMAGE STIMULUS | 21 | 720 | 9.111e-18 | 1.843e-15 |
| 24 | MITOTIC DNA INTEGRITY CHECKPOINT | 12 | 100 | 1.282e-17 | 2.485e-15 |
| 25 | REGULATION OF PROTEIN MODIFICATION PROCESS | 28 | 1710 | 1.397e-17 | 2.6e-15 |
| 26 | CELLULAR RESPONSE TO STRESS | 27 | 1565 | 1.982e-17 | 3.548e-15 |
| 27 | NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION | 13 | 146 | 2.731e-17 | 4.539e-15 |
| 28 | DNA INTEGRITY CHECKPOINT | 13 | 146 | 2.731e-17 | 4.539e-15 |
| 29 | REGULATION OF CELL CYCLE PROCESS | 19 | 558 | 2.945e-17 | 4.726e-15 |
| 30 | NEGATIVE REGULATION OF MITOTIC CELL CYCLE | 14 | 199 | 4.024e-17 | 6.242e-15 |
| 31 | POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS | 26 | 1492 | 8.403e-17 | 1.261e-14 |
| 32 | RESPONSE TO ABIOTIC STIMULUS | 22 | 1024 | 7.262e-16 | 1.056e-13 |
| 33 | MITOTIC CELL CYCLE CHECKPOINT | 12 | 139 | 7.59e-16 | 1.07e-13 |
| 34 | APOPTOTIC SIGNALING PATHWAY | 14 | 289 | 7.435e-15 | 9.884e-13 |
| 35 | REGULATION OF PHOSPHORUS METABOLIC PROCESS | 25 | 1618 | 7.257e-15 | 9.884e-13 |
| 36 | REGULATION OF KINASE ACTIVITY | 19 | 776 | 1.216e-14 | 1.571e-12 |
| 37 | REGULATION OF CELL PROLIFERATION | 24 | 1496 | 1.433e-14 | 1.802e-12 |
| 38 | REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 16 | 470 | 1.588e-14 | 1.945e-12 |
| 39 | REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 10 | 97 | 3.915e-14 | 4.671e-12 |
| 40 | CELL CYCLE PHASE TRANSITION | 13 | 255 | 4.043e-14 | 4.703e-12 |
| 41 | CELLULAR RESPONSE TO ABIOTIC STIMULUS | 13 | 263 | 6.015e-14 | 6.826e-12 |
| 42 | INTRACELLULAR SIGNAL TRANSDUCTION | 23 | 1572 | 4.564e-13 | 5.057e-11 |
| 43 | RESPONSE TO STEROID HORMONE | 15 | 497 | 6.99e-13 | 7.564e-11 |
| 44 | REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION | 23 | 1656 | 1.355e-12 | 1.433e-10 |
| 45 | POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION | 18 | 876 | 1.424e-12 | 1.473e-10 |
| 46 | ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY | 9 | 95 | 1.783e-12 | 1.735e-10 |
| 47 | RESPONSE TO LIPID | 18 | 888 | 1.79e-12 | 1.735e-10 |
| 48 | RESPONSE TO DRUG | 14 | 431 | 1.748e-12 | 1.735e-10 |
| 49 | POSITIVE REGULATION OF PROTEOLYSIS | 13 | 363 | 3.627e-12 | 3.309e-10 |
| 50 | RESPONSE TO ALCOHOL | 13 | 362 | 3.503e-12 | 3.309e-10 |
| 51 | REGULATION OF APOPTOTIC SIGNALING PATHWAY | 13 | 363 | 3.627e-12 | 3.309e-10 |
| 52 | INTRINSIC APOPTOTIC SIGNALING PATHWAY | 10 | 152 | 3.775e-12 | 3.378e-10 |
| 53 | REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY | 11 | 213 | 4.007e-12 | 3.517e-10 |
| 54 | CELL CYCLE ARREST | 10 | 154 | 4.304e-12 | 3.708e-10 |
| 55 | RESPONSE TO ESTROGEN | 11 | 218 | 5.157e-12 | 4.362e-10 |
| 56 | CELL CYCLE G1 S PHASE TRANSITION | 9 | 111 | 7.443e-12 | 6.076e-10 |
| 57 | G1 S TRANSITION OF MITOTIC CELL CYCLE | 9 | 111 | 7.443e-12 | 6.076e-10 |
| 58 | ZYMOGEN ACTIVATION | 9 | 112 | 8.079e-12 | 6.481e-10 |
| 59 | REGULATION OF PROTEOLYSIS | 16 | 711 | 8.784e-12 | 6.928e-10 |
| 60 | POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS | 19 | 1135 | 1.031e-11 | 7.997e-10 |
| 61 | RESPONSE TO OXYGEN LEVELS | 12 | 311 | 1.158e-11 | 8.835e-10 |
| 62 | POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY | 10 | 171 | 1.225e-11 | 9.195e-10 |
| 63 | RESPONSE TO TOXIC SUBSTANCE | 11 | 241 | 1.529e-11 | 1.129e-09 |
| 64 | RESPONSE TO UV | 9 | 126 | 2.359e-11 | 1.715e-09 |
| 65 | RESPONSE TO METAL ION | 12 | 333 | 2.566e-11 | 1.837e-09 |
| 66 | RESPONSE TO OXYGEN CONTAINING COMPOUND | 20 | 1381 | 3.375e-11 | 2.38e-09 |
| 67 | AGING | 11 | 264 | 4.08e-11 | 2.833e-09 |
| 68 | CELLULAR RESPONSE TO RADIATION | 9 | 137 | 5.029e-11 | 3.441e-09 |
| 69 | REPLICATIVE SENESCENCE | 5 | 12 | 6.214e-11 | 4.19e-09 |
| 70 | RESPONSE TO ESTRADIOL | 9 | 146 | 8.917e-11 | 5.927e-09 |
| 71 | REGULATION OF CELL CYCLE G2 M PHASE TRANSITION | 7 | 59 | 1.218e-10 | 7.981e-09 |
| 72 | REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY | 9 | 153 | 1.357e-10 | 8.773e-09 |
| 73 | POSITIVE REGULATION OF PEPTIDASE ACTIVITY | 9 | 154 | 1.439e-10 | 9.172e-09 |
| 74 | REGULATION OF PEPTIDASE ACTIVITY | 12 | 392 | 1.687e-10 | 1.061e-08 |
| 75 | POSITIVE REGULATION OF CATALYTIC ACTIVITY | 20 | 1518 | 1.839e-10 | 1.141e-08 |
| 76 | REGULATION OF SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 9 | 162 | 2.263e-10 | 1.386e-08 |
| 77 | POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS | 17 | 1036 | 2.38e-10 | 1.42e-08 |
| 78 | POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS | 17 | 1036 | 2.38e-10 | 1.42e-08 |
| 79 | RESPONSE TO HORMONE | 16 | 893 | 2.58e-10 | 1.52e-08 |
| 80 | CELLULAR RESPONSE TO UV | 7 | 66 | 2.744e-10 | 1.579e-08 |
| 81 | NEURON APOPTOTIC PROCESS | 6 | 35 | 2.749e-10 | 1.579e-08 |
| 82 | RESPONSE TO RADIATION | 12 | 413 | 3.066e-10 | 1.74e-08 |
| 83 | NEGATIVE REGULATION OF CELL PROLIFERATION | 14 | 643 | 3.527e-10 | 1.977e-08 |
| 84 | RESPONSE TO ORGANIC CYCLIC COMPOUND | 16 | 917 | 3.803e-10 | 2.107e-08 |
| 85 | INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE | 7 | 71 | 4.641e-10 | 2.511e-08 |
| 86 | POSITIVE REGULATION OF MOLECULAR FUNCTION | 21 | 1791 | 4.621e-10 | 2.511e-08 |
| 87 | NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS | 17 | 1087 | 4.987e-10 | 2.667e-08 |
| 88 | REGULATION OF RESPONSE TO STRESS | 19 | 1468 | 8.42e-10 | 4.452e-08 |
| 89 | CELLULAR RESPONSE TO EXTERNAL STIMULUS | 10 | 264 | 8.746e-10 | 4.573e-08 |
| 90 | CELL DIVISION | 12 | 460 | 1.045e-09 | 5.402e-08 |
| 91 | REGULATION OF FIBROBLAST PROLIFERATION | 7 | 81 | 1.191e-09 | 6.089e-08 |
| 92 | RESPONSE TO INORGANIC SUBSTANCE | 12 | 479 | 1.651e-09 | 8.351e-08 |
| 93 | NEURON DEATH | 6 | 47 | 1.778e-09 | 8.895e-08 |
| 94 | NEGATIVE REGULATION OF CELL DEATH | 15 | 872 | 1.871e-09 | 9.26e-08 |
| 95 | RESPONSE TO IONIZING RADIATION | 8 | 145 | 2.609e-09 | 1.278e-07 |
| 96 | CELLULAR RESPONSE TO LIGHT STIMULUS | 7 | 91 | 2.72e-09 | 1.318e-07 |
| 97 | DNA METABOLIC PROCESS | 14 | 758 | 2.958e-09 | 1.419e-07 |
| 98 | INTRINSIC APOPTOTIC SIGNALING PATHWAY BY P53 CLASS MEDIATOR | 6 | 53 | 3.758e-09 | 1.784e-07 |
| 99 | NEGATIVE REGULATION OF MOLECULAR FUNCTION | 16 | 1079 | 3.997e-09 | 1.879e-07 |
| 100 | REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS | 6 | 55 | 4.728e-09 | 2.2e-07 |
| 101 | EXTRINSIC APOPTOTIC SIGNALING PATHWAY | 7 | 99 | 4.928e-09 | 2.27e-07 |
| 102 | RESPONSE TO ENDOGENOUS STIMULUS | 18 | 1450 | 5.315e-09 | 2.425e-07 |
| 103 | REGENERATION | 8 | 161 | 5.967e-09 | 2.695e-07 |
| 104 | NEGATIVE REGULATION OF CATALYTIC ACTIVITY | 14 | 829 | 9.255e-09 | 4.141e-07 |
| 105 | REGULATION OF CELLULAR RESPONSE TO STRESS | 13 | 691 | 9.754e-09 | 4.322e-07 |
| 106 | RESPONSE TO X RAY | 5 | 30 | 1.081e-08 | 4.745e-07 |
| 107 | RESPONSE TO CORTICOSTEROID | 8 | 176 | 1.201e-08 | 5.224e-07 |
| 108 | POSITIVE REGULATION OF CELL COMMUNICATION | 18 | 1532 | 1.26e-08 | 5.428e-07 |
| 109 | NEGATIVE REGULATION OF TRANSFERASE ACTIVITY | 10 | 351 | 1.343e-08 | 5.735e-07 |
| 110 | RESPONSE TO KETONE | 8 | 182 | 1.562e-08 | 6.605e-07 |
| 111 | CELL AGING | 6 | 67 | 1.591e-08 | 6.67e-07 |
| 112 | PROTEIN MATURATION | 9 | 265 | 1.713e-08 | 7.118e-07 |
| 113 | ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 4 | 13 | 2.43e-08 | 9.919e-07 |
| 114 | RESPONSE TO COBALT ION | 4 | 13 | 2.43e-08 | 9.919e-07 |
| 115 | POSITIVE REGULATION OF TRANSFERASE ACTIVITY | 12 | 616 | 2.727e-08 | 1.103e-06 |
| 116 | RESPONSE TO LIGHT STIMULUS | 9 | 280 | 2.755e-08 | 1.105e-06 |
| 117 | POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 5 | 36 | 2.827e-08 | 1.124e-06 |
| 118 | RESPONSE TO EXTERNAL STIMULUS | 19 | 1821 | 2.952e-08 | 1.164e-06 |
| 119 | NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY | 8 | 200 | 3.256e-08 | 1.273e-06 |
| 120 | EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS | 5 | 39 | 4.294e-08 | 1.665e-06 |
| 121 | DNA REPLICATION | 8 | 208 | 4.414e-08 | 1.698e-06 |
| 122 | ORGAN REGENERATION | 6 | 83 | 5.839e-08 | 2.227e-06 |
| 123 | REGULATION OF PROTEIN STABILITY | 8 | 221 | 7.054e-08 | 2.668e-06 |
| 124 | REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 5 | 43 | 7.125e-08 | 2.674e-06 |
| 125 | POSITIVE REGULATION OF RESPONSE TO STIMULUS | 19 | 1929 | 7.458e-08 | 2.776e-06 |
| 126 | NEGATIVE REGULATION OF PHOSPHORYLATION | 10 | 422 | 7.603e-08 | 2.808e-06 |
| 127 | POSITIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 4 | 17 | 8.03e-08 | 2.942e-06 |
| 128 | RESPONSE TO ANTIBIOTIC | 5 | 47 | 1.127e-07 | 4.065e-06 |
| 129 | POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS | 5 | 47 | 1.127e-07 | 4.065e-06 |
| 130 | RESPONSE TO NITROGEN COMPOUND | 13 | 859 | 1.254e-07 | 4.489e-06 |
| 131 | PROTEOLYSIS | 15 | 1208 | 1.445e-07 | 5.134e-06 |
| 132 | NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY | 6 | 98 | 1.583e-07 | 5.58e-06 |
| 133 | NEGATIVE REGULATION OF CELL CYCLE ARREST | 4 | 20 | 1.626e-07 | 5.687e-06 |
| 134 | POSITIVE REGULATION OF FIBROBLAST PROLIFERATION | 5 | 53 | 2.085e-07 | 7.185e-06 |
| 135 | POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY | 5 | 53 | 2.085e-07 | 7.185e-06 |
| 136 | POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION | 9 | 360 | 2.347e-07 | 8.028e-06 |
| 137 | POSITIVE REGULATION OF PROTEIN OLIGOMERIZATION | 4 | 22 | 2.445e-07 | 8.245e-06 |
| 138 | REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 4 | 22 | 2.445e-07 | 8.245e-06 |
| 139 | POSITIVE REGULATION OF KINASE ACTIVITY | 10 | 482 | 2.607e-07 | 8.727e-06 |
| 140 | NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS | 11 | 616 | 2.713e-07 | 9.018e-06 |
| 141 | HISTONE PHOSPHORYLATION | 4 | 25 | 4.205e-07 | 1.388e-05 |
| 142 | RESPONSE TO CORTICOSTERONE | 4 | 26 | 4.961e-07 | 1.626e-05 |
| 143 | POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 8 | 289 | 5.473e-07 | 1.781e-05 |
| 144 | POSITIVE REGULATION OF MITOTIC CELL CYCLE | 6 | 123 | 6.095e-07 | 1.97e-05 |
| 145 | NEGATIVE REGULATION OF RESPONSE TO STIMULUS | 15 | 1360 | 6.64e-07 | 2.131e-05 |
| 146 | POSITIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS | 4 | 28 | 6.769e-07 | 2.157e-05 |
| 147 | POSITIVE REGULATION OF NEURON DEATH | 5 | 67 | 6.834e-07 | 2.163e-05 |
| 148 | NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS | 10 | 541 | 7.495e-07 | 2.34e-05 |
| 149 | NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS | 10 | 541 | 7.495e-07 | 2.34e-05 |
| 150 | REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 4 | 29 | 7.838e-07 | 2.415e-05 |
| 151 | POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 4 | 29 | 7.838e-07 | 2.415e-05 |
| 152 | NEGATIVE REGULATION OF CELL COMMUNICATION | 14 | 1192 | 8.191e-07 | 2.507e-05 |
| 153 | REGULATION OF MEMBRANE PERMEABILITY | 5 | 70 | 8.516e-07 | 2.59e-05 |
| 154 | RESPONSE TO MECHANICAL STIMULUS | 7 | 210 | 8.672e-07 | 2.62e-05 |
| 155 | INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE BY P53 CLASS MEDIATOR | 4 | 30 | 9.027e-07 | 2.642e-05 |
| 156 | NEGATIVE REGULATION OF B CELL ACTIVATION | 4 | 30 | 9.027e-07 | 2.642e-05 |
| 157 | NEGATIVE REGULATION OF CELL MATRIX ADHESION | 4 | 30 | 9.027e-07 | 2.642e-05 |
| 158 | PROTEIN STABILIZATION | 6 | 131 | 8.83e-07 | 2.642e-05 |
| 159 | REGULATION OF CELLULAR PROTEIN LOCALIZATION | 10 | 552 | 8.996e-07 | 2.642e-05 |
| 160 | REGULATION OF MITOCHONDRION ORGANIZATION | 7 | 218 | 1.114e-06 | 3.239e-05 |
| 161 | NEGATIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 4 | 32 | 1.18e-06 | 3.411e-05 |
| 162 | CELL CYCLE G2 M PHASE TRANSITION | 6 | 138 | 1.198e-06 | 3.441e-05 |
| 163 | REGULATION OF PROTEIN EXPORT FROM NUCLEUS | 4 | 33 | 1.34e-06 | 3.78e-05 |
| 164 | SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND | 4 | 33 | 1.34e-06 | 3.78e-05 |
| 165 | EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND | 4 | 33 | 1.34e-06 | 3.78e-05 |
| 166 | CELLULAR RESPONSE TO OXYGEN LEVELS | 6 | 143 | 1.475e-06 | 4.134e-05 |
| 167 | NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS | 4 | 34 | 1.516e-06 | 4.225e-05 |
| 168 | REGULATION OF LEUKOCYTE APOPTOTIC PROCESS | 5 | 79 | 1.559e-06 | 4.319e-05 |
| 169 | CELLULAR RESPONSE TO MECHANICAL STIMULUS | 5 | 80 | 1.66e-06 | 4.571e-05 |
| 170 | REGULATION OF PROTEIN OLIGOMERIZATION | 4 | 35 | 1.709e-06 | 4.65e-05 |
| 171 | RESPONSE TO MINERALOCORTICOID | 4 | 35 | 1.709e-06 | 4.65e-05 |
| 172 | RESPONSE TO TRANSITION METAL NANOPARTICLE | 6 | 148 | 1.802e-06 | 4.876e-05 |
| 173 | REGULATION OF DNA METABOLIC PROCESS | 8 | 340 | 1.852e-06 | 4.981e-05 |
| 174 | POSITIVE REGULATION OF MAPK CASCADE | 9 | 470 | 2.156e-06 | 5.766e-05 |
| 175 | ACTIVATION OF MAPKKK ACTIVITY | 3 | 11 | 2.392e-06 | 6.36e-05 |
| 176 | REGULATION OF INTRACELLULAR TRANSPORT | 10 | 621 | 2.595e-06 | 6.86e-05 |
| 177 | NEGATIVE REGULATION OF KINASE ACTIVITY | 7 | 250 | 2.77e-06 | 7.281e-05 |
| 178 | REGULATION OF NEURON DEATH | 7 | 252 | 2.919e-06 | 7.631e-05 |
| 179 | REGULATION OF CELL MATRIX ADHESION | 5 | 90 | 2.979e-06 | 7.743e-05 |
| 180 | MITOCHONDRIAL MEMBRANE ORGANIZATION | 5 | 92 | 3.32e-06 | 8.583e-05 |
| 181 | POSITIVE REGULATION OF INTRACELLULAR TRANSPORT | 8 | 370 | 3.466e-06 | 8.91e-05 |
| 182 | RESPONSE TO CARBOHYDRATE | 6 | 168 | 3.759e-06 | 9.61e-05 |
| 183 | REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA | 4 | 44 | 4.358e-06 | 0.0001108 |
| 184 | POSITIVE REGULATION OF P38MAPK CASCADE | 3 | 14 | 5.249e-06 | 0.0001327 |
| 185 | NEGATIVE REGULATION OF B CELL PROLIFERATION | 3 | 15 | 6.549e-06 | 0.0001647 |
| 186 | RESPONSE TO GAMMA RADIATION | 4 | 50 | 7.312e-06 | 0.0001829 |
| 187 | REGULATION OF NEURON APOPTOTIC PROCESS | 6 | 192 | 8.096e-06 | 0.0002015 |
| 188 | CELLULAR RESPONSE TO IONIZING RADIATION | 4 | 52 | 8.564e-06 | 0.0002108 |
| 189 | POSITIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY | 4 | 52 | 8.564e-06 | 0.0002108 |
| 190 | RHYTHMIC PROCESS | 7 | 298 | 8.768e-06 | 0.0002147 |
| 191 | NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION | 4 | 53 | 9.246e-06 | 0.0002252 |
| 192 | REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS | 4 | 54 | 9.967e-06 | 0.0002416 |
| 193 | POSITIVE REGULATION OF ORGANELLE ORGANIZATION | 9 | 573 | 1.073e-05 | 0.0002573 |
| 194 | REGULATION OF B CELL PROLIFERATION | 4 | 55 | 1.073e-05 | 0.0002573 |
| 195 | REGULATION OF CATABOLIC PROCESS | 10 | 731 | 1.093e-05 | 0.0002607 |
| 196 | RESPONSE TO EXTRACELLULAR STIMULUS | 8 | 441 | 1.25e-05 | 0.0002968 |
| 197 | REGULATION OF B CELL ACTIVATION | 5 | 121 | 1.271e-05 | 0.0003003 |
| 198 | POSITIVE REGULATION OF PROTEIN EXPORT FROM NUCLEUS | 3 | 19 | 1.385e-05 | 0.0003255 |
| 199 | RESPONSE TO MOLECULE OF BACTERIAL ORIGIN | 7 | 321 | 1.42e-05 | 0.000332 |
| 200 | MITOCHONDRION ORGANIZATION | 9 | 594 | 1.429e-05 | 0.0003325 |
| 201 | PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS | 16 | 1977 | 1.465e-05 | 0.0003392 |
| 202 | NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 5 | 126 | 1.547e-05 | 0.0003564 |
| 203 | REGULATION OF HYDROLASE ACTIVITY | 13 | 1327 | 1.599e-05 | 0.0003666 |
| 204 | POSITIVE REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS | 3 | 20 | 1.627e-05 | 0.000371 |
| 205 | REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION | 5 | 128 | 1.67e-05 | 0.000379 |
| 206 | REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT | 6 | 220 | 1.756e-05 | 0.0003966 |
| 207 | CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND | 8 | 465 | 1.832e-05 | 0.0004118 |
| 208 | RESPONSE TO ETHANOL | 5 | 136 | 2.238e-05 | 0.0005006 |
| 209 | DNA REPAIR | 8 | 480 | 2.3e-05 | 0.0005121 |
| 210 | CIRCADIAN RHYTHM | 5 | 137 | 2.318e-05 | 0.0005137 |
| 211 | REGULATION OF GROWTH | 9 | 633 | 2.364e-05 | 0.0005212 |
| 212 | RESPONSE TO MAGNESIUM ION | 3 | 23 | 2.514e-05 | 0.000544 |
| 213 | RESPONSE TO INCREASED OXYGEN LEVELS | 3 | 23 | 2.514e-05 | 0.000544 |
| 214 | RESPONSE TO HYPEROXIA | 3 | 23 | 2.514e-05 | 0.000544 |
| 215 | POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION | 4 | 68 | 2.502e-05 | 0.000544 |
| 216 | RESPONSE TO OXIDATIVE STRESS | 7 | 352 | 2.568e-05 | 0.0005532 |
| 217 | RAS PROTEIN SIGNAL TRANSDUCTION | 5 | 143 | 2.849e-05 | 0.0006109 |
| 218 | REGULATION OF EXECUTION PHASE OF APOPTOSIS | 3 | 24 | 2.868e-05 | 0.0006121 |
| 219 | REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY | 5 | 145 | 3.046e-05 | 0.0006442 |
| 220 | REGULATION OF RESPONSE TO DNA DAMAGE STIMULUS | 5 | 145 | 3.046e-05 | 0.0006442 |
| 221 | REGULATION OF MAPK CASCADE | 9 | 660 | 3.28e-05 | 0.0006905 |
| 222 | REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS | 5 | 148 | 3.36e-05 | 0.0007042 |
| 223 | REGULATION OF P38MAPK CASCADE | 3 | 26 | 3.671e-05 | 0.0007659 |
| 224 | RESPONSE TO BACTERIUM | 8 | 528 | 4.528e-05 | 0.0009405 |
| 225 | REGULATION OF DNA DAMAGE RESPONSE SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 3 | 28 | 4.609e-05 | 0.0009489 |
| 226 | POSITIVE REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA | 3 | 28 | 4.609e-05 | 0.0009489 |
| 227 | REGULATION OF PROTEIN CATABOLIC PROCESS | 7 | 393 | 5.171e-05 | 0.00106 |
| 228 | REGULATION OF NUCLEAR DIVISION | 5 | 163 | 5.327e-05 | 0.001087 |
| 229 | REGULATION OF CELLULAR LOCALIZATION | 12 | 1277 | 5.476e-05 | 0.001113 |
| 230 | RESPONSE TO BIOTIC STIMULUS | 10 | 886 | 5.662e-05 | 0.001145 |
| 231 | POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION | 5 | 167 | 5.978e-05 | 0.001203 |
| 232 | REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS | 6 | 274 | 5.998e-05 | 0.001203 |
| 233 | POSITIVE REGULATION OF GENE EXPRESSION | 14 | 1733 | 6.039e-05 | 0.001206 |
| 234 | POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS | 4 | 86 | 6.311e-05 | 0.001255 |
| 235 | REPRODUCTION | 12 | 1297 | 6.366e-05 | 0.001261 |
| 236 | ACTIVATION OF PROTEIN KINASE ACTIVITY | 6 | 279 | 6.629e-05 | 0.001307 |
| 237 | REGULATION OF CELL SUBSTRATE ADHESION | 5 | 173 | 7.067e-05 | 0.001387 |
| 238 | REGULATION OF EPITHELIAL CELL PROLIFERATION | 6 | 285 | 7.456e-05 | 0.001458 |
| 239 | CELLULAR SENESCENCE | 3 | 33 | 7.608e-05 | 0.001475 |
| 240 | REGULATION OF CELL AGING | 3 | 33 | 7.608e-05 | 0.001475 |
| 241 | MITOCHONDRIAL TRANSPORT | 5 | 177 | 7.874e-05 | 0.00152 |
| 242 | T CELL HOMEOSTASIS | 3 | 34 | 8.33e-05 | 0.001589 |
| 243 | PROTEIN DESTABILIZATION | 3 | 34 | 8.33e-05 | 0.001589 |
| 244 | PROTEIN KINASE B SIGNALING | 3 | 34 | 8.33e-05 | 0.001589 |
| 245 | PROTEIN CATABOLIC PROCESS | 8 | 579 | 8.639e-05 | 0.001641 |
| 246 | REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS | 5 | 181 | 8.75e-05 | 0.001655 |
| 247 | NEGATIVE REGULATION OF PROTEIN PROCESSING | 3 | 35 | 9.095e-05 | 0.001693 |
| 248 | NEGATIVE REGULATION OF PROTEIN MATURATION | 3 | 35 | 9.095e-05 | 0.001693 |
| 249 | RESPONSE TO IRON ION | 3 | 35 | 9.095e-05 | 0.001693 |
| 250 | REGULATION OF RESPONSE TO REACTIVE OXYGEN SPECIES | 3 | 35 | 9.095e-05 | 0.001693 |
| 251 | POSITIVE REGULATION OF DEVELOPMENTAL PROCESS | 11 | 1142 | 9.551e-05 | 0.001771 |
| 252 | PROTEIN OLIGOMERIZATION | 7 | 434 | 9.634e-05 | 0.001772 |
| 253 | PROTEIN PHOSPHORYLATION | 10 | 944 | 9.608e-05 | 0.001772 |
| 254 | POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 3 | 36 | 9.904e-05 | 0.001814 |
| 255 | NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION | 7 | 437 | 0.0001006 | 0.001835 |
| 256 | REGULATION OF PROTEIN LOCALIZATION | 10 | 950 | 0.0001013 | 0.00184 |
| 257 | POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION | 11 | 1152 | 0.0001032 | 0.001869 |
| 258 | CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS | 5 | 188 | 0.0001046 | 0.001887 |
| 259 | RESPONSE TO NUTRIENT | 5 | 191 | 0.0001127 | 0.002017 |
| 260 | RESPONSE TO REACTIVE OXYGEN SPECIES | 5 | 191 | 0.0001127 | 0.002017 |
| 261 | DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION | 8 | 602 | 0.0001132 | 0.002017 |
| 262 | LIMBIC SYSTEM DEVELOPMENT | 4 | 100 | 0.0001136 | 0.002017 |
| 263 | REGULATION OF ORGANELLE ORGANIZATION | 11 | 1178 | 0.0001259 | 0.002227 |
| 264 | CELLULAR RESPONSE TO LIPID | 7 | 457 | 0.0001327 | 0.002339 |
| 265 | REGULATION OF IMMUNE SYSTEM PROCESS | 12 | 1403 | 0.000135 | 0.00237 |
| 266 | CELLULAR RESPONSE TO ESTROGEN STIMULUS | 3 | 41 | 0.0001466 | 0.002564 |
| 267 | REGULATION OF LEUKOCYTE PROLIFERATION | 5 | 206 | 0.0001605 | 0.002798 |
| 268 | NEGATIVE REGULATION OF PROTEOLYSIS | 6 | 329 | 0.0001635 | 0.002833 |
| 269 | POSITIVE REGULATION OF CELL PROLIFERATION | 9 | 814 | 0.0001638 | 0.002833 |
| 270 | REGULATION OF CYTOPLASMIC TRANSPORT | 7 | 481 | 0.0001819 | 0.003123 |
| 271 | PHOSPHORYLATION | 11 | 1228 | 0.0001816 | 0.003123 |
| 272 | REGULATION OF CELL ACTIVATION | 7 | 484 | 0.000189 | 0.003232 |
| 273 | CELLULAR RESPONSE TO STEROID HORMONE STIMULUS | 5 | 218 | 0.0002089 | 0.003561 |
| 274 | NEGATIVE REGULATION OF CELL ADHESION | 5 | 223 | 0.0002321 | 0.003941 |
| 275 | POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT | 4 | 121 | 0.0002368 | 0.004006 |
| 276 | REGULATION OF SMOOTH MUSCLE CELL MIGRATION | 3 | 49 | 0.0002498 | 0.004211 |
| 277 | TELENCEPHALON DEVELOPMENT | 5 | 228 | 0.0002571 | 0.004319 |
| 278 | LYMPHOCYTE HOMEOSTASIS | 3 | 50 | 0.0002653 | 0.00444 |
| 279 | POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION | 7 | 514 | 0.0002727 | 0.004547 |
| 280 | RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 5 | 233 | 0.0002842 | 0.004722 |
| 281 | NEGATIVE REGULATION OF GROWTH | 5 | 236 | 0.0003014 | 0.004991 |
| 282 | REGULATION OF LIGASE ACTIVITY | 4 | 130 | 0.0003114 | 0.005138 |
| 283 | NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS | 6 | 372 | 0.0003168 | 0.005208 |
| 284 | PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS | 4 | 134 | 0.0003494 | 0.005725 |
| 285 | POSITIVE REGULATION OF HYDROLASE ACTIVITY | 9 | 905 | 0.0003597 | 0.005854 |
| 286 | REGULATION OF INTRACELLULAR PROTEIN TRANSPORT | 6 | 381 | 0.0003598 | 0.005854 |
| 287 | REGULATION OF TRANSPORT | 13 | 1804 | 0.0003693 | 0.005987 |
| 288 | RESPONSE TO ALKALOID | 4 | 137 | 0.0003801 | 0.006141 |
| 289 | APOPTOTIC MITOCHONDRIAL CHANGES | 3 | 57 | 0.0003912 | 0.006298 |
| 290 | DEOXYRIBONUCLEOTIDE BIOSYNTHETIC PROCESS | 2 | 12 | 0.0003979 | 0.00634 |
| 291 | POSITIVE REGULATION OF EXECUTION PHASE OF APOPTOSIS | 2 | 12 | 0.0003979 | 0.00634 |
| 292 | POSITIVE REGULATION OF INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY | 2 | 12 | 0.0003979 | 0.00634 |
| 293 | PROTEIN COMPLEX BIOGENESIS | 10 | 1132 | 0.0004187 | 0.006626 |
| 294 | PROTEIN COMPLEX ASSEMBLY | 10 | 1132 | 0.0004187 | 0.006626 |
| 295 | MACROMOLECULE CATABOLIC PROCESS | 9 | 926 | 0.0004254 | 0.00671 |
| 296 | REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS | 3 | 59 | 0.0004331 | 0.006808 |
| 297 | POSITIVE REGULATION OF CATABOLIC PROCESS | 6 | 395 | 0.0004357 | 0.006827 |
| 298 | LEUKOCYTE HOMEOSTASIS | 3 | 60 | 0.0004551 | 0.007106 |
| 299 | POSITIVE REGULATION OF TRANSPORT | 9 | 936 | 0.0004601 | 0.007159 |
| 300 | POSITIVE REGULATION OF DNA DAMAGE RESPONSE SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 2 | 13 | 0.0004694 | 0.007185 |
| 301 | MITOTIC CELL CYCLE ARREST | 2 | 13 | 0.0004694 | 0.007185 |
| 302 | CELLULAR RESPONSE TO ORGANIC SUBSTANCE | 13 | 1848 | 0.0004664 | 0.007185 |
| 303 | HEPATOCYTE APOPTOTIC PROCESS | 2 | 13 | 0.0004694 | 0.007185 |
| 304 | REGULATION OF HISTONE PHOSPHORYLATION | 2 | 13 | 0.0004694 | 0.007185 |
| 305 | RESPONSE TO TEMPERATURE STIMULUS | 4 | 148 | 0.000509 | 0.007765 |
| 306 | REPRODUCTIVE SYSTEM DEVELOPMENT | 6 | 408 | 0.000517 | 0.007861 |
| 307 | POSITIVE REGULATION OF CHROMOSOME ORGANIZATION | 4 | 150 | 0.0005354 | 0.008115 |
| 308 | MITOCHONDRIAL DNA METABOLIC PROCESS | 2 | 14 | 0.0005468 | 0.008155 |
| 309 | REGULATION OF FIBRINOLYSIS | 2 | 14 | 0.0005468 | 0.008155 |
| 310 | POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND | 2 | 14 | 0.0005468 | 0.008155 |
| 311 | DETERMINATION OF ADULT LIFESPAN | 2 | 14 | 0.0005468 | 0.008155 |
| 312 | REGULATION OF SMOOTH MUSCLE CELL APOPTOTIC PROCESS | 2 | 14 | 0.0005468 | 0.008155 |
| 313 | MACROMOLECULAR COMPLEX ASSEMBLY | 11 | 1398 | 0.0005536 | 0.00823 |
| 314 | REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS | 4 | 152 | 0.0005628 | 0.008313 |
| 315 | REGULATION OF CHROMATIN ORGANIZATION | 4 | 152 | 0.0005628 | 0.008313 |
| 316 | IMMUNE SYSTEM DEVELOPMENT | 7 | 582 | 0.0005748 | 0.008414 |
| 317 | PALLIUM DEVELOPMENT | 4 | 153 | 0.0005768 | 0.008414 |
| 318 | REGULATION OF CELL DIVISION | 5 | 272 | 0.0005763 | 0.008414 |
| 319 | REGULATION OF RESPONSE TO OXIDATIVE STRESS | 3 | 65 | 0.0005758 | 0.008414 |
| 320 | DENTATE GYRUS DEVELOPMENT | 2 | 15 | 0.0006299 | 0.009046 |
| 321 | RESPONSE TO VITAMIN E | 2 | 15 | 0.0006299 | 0.009046 |
| 322 | T CELL APOPTOTIC PROCESS | 2 | 15 | 0.0006299 | 0.009046 |
| 323 | REGULATION OF SISTER CHROMATID SEGREGATION | 3 | 67 | 0.0006293 | 0.009046 |
| 324 | DNA DAMAGE RESPONSE SIGNAL TRANSDUCTION RESULTING IN TRANSCRIPTION | 2 | 15 | 0.0006299 | 0.009046 |
| 325 | REGULATION OF CHROMOSOME ORGANIZATION | 5 | 278 | 0.0006361 | 0.009107 |
| 326 | NEGATIVE REGULATION OF CELL ACTIVATION | 4 | 158 | 0.0006508 | 0.009261 |
| 327 | RESPONSE TO PURINE CONTAINING COMPOUND | 4 | 158 | 0.0006508 | 0.009261 |
| 328 | CELL DEVELOPMENT | 11 | 1426 | 0.0006539 | 0.009277 |
| 329 | REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL | 5 | 280 | 0.000657 | 0.009292 |
| 330 | REGULATION OF JNK CASCADE | 4 | 159 | 0.0006664 | 0.009396 |
| 331 | POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT | 5 | 282 | 0.0006784 | 0.009514 |
| 332 | REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT | 12 | 1672 | 0.0006788 | 0.009514 |
| 333 | NEGATIVE REGULATION OF LEUKOCYTE PROLIFERATION | 3 | 69 | 0.0006858 | 0.009583 |
| 334 | CARDIOVASCULAR SYSTEM DEVELOPMENT | 8 | 788 | 0.0006936 | 0.009633 |
| 335 | CIRCULATORY SYSTEM DEVELOPMENT | 8 | 788 | 0.0006936 | 0.009633 |
| 336 | REGULATION OF DNA REPLICATION | 4 | 161 | 0.0006983 | 0.009671 |
| 337 | REGULATION OF MAMMARY GLAND EPITHELIAL CELL PROLIFERATION | 2 | 16 | 0.0007188 | 0.009836 |
| 338 | NEGATIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION | 2 | 16 | 0.0007188 | 0.009836 |
| 339 | NEGATIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION | 2 | 16 | 0.0007188 | 0.009836 |
| 340 | REGULATION OF PROTEIN HOMOOLIGOMERIZATION | 2 | 16 | 0.0007188 | 0.009836 |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE REGULATOR ACTIVITY | 7 | 28 | 4.481e-13 | 4.163e-10 |
| 2 | KINASE BINDING | 13 | 606 | 2.024e-09 | 6.267e-07 |
| 3 | ENZYME BINDING | 20 | 1737 | 1.975e-09 | 6.267e-07 |
| 4 | P53 BINDING | 6 | 67 | 1.591e-08 | 3.695e-06 |
| 5 | CYCLIN BINDING | 4 | 19 | 1.303e-07 | 2.421e-05 |
| 6 | KINASE REGULATOR ACTIVITY | 7 | 186 | 3.829e-07 | 5.082e-05 |
| 7 | PROTEIN COMPLEX BINDING | 13 | 935 | 3.324e-07 | 5.082e-05 |
| 8 | MACROMOLECULAR COMPLEX BINDING | 15 | 1399 | 9.503e-07 | 0.0001104 |
| 9 | CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 4 | 34 | 1.516e-06 | 0.0001565 |
| 10 | CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY | 3 | 12 | 3.184e-06 | 0.0002958 |
| 11 | CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC PROCESS | 3 | 15 | 6.549e-06 | 0.0005531 |
| 12 | DEATH RECEPTOR BINDING | 3 | 18 | 1.168e-05 | 0.0009045 |
| 13 | HISTONE KINASE ACTIVITY | 3 | 19 | 1.385e-05 | 0.0009898 |
| 14 | PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY | 3 | 30 | 5.692e-05 | 0.003777 |
| 15 | ENZYME REGULATOR ACTIVITY | 10 | 959 | 0.0001095 | 0.006779 |
| 16 | PROTEASE BINDING | 4 | 104 | 0.0001322 | 0.007676 |
| 17 | PROTEIN KINASE ACTIVITY | 8 | 640 | 0.0001723 | 0.009418 |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX | 7 | 31 | 9.895e-13 | 5.779e-10 |
| 2 | PROTEIN KINASE COMPLEX | 7 | 90 | 2.516e-09 | 7.345e-07 |
| 3 | TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS | 8 | 237 | 1.208e-07 | 2.351e-05 |
| 4 | CATALYTIC COMPLEX | 13 | 1038 | 1.085e-06 | 0.0001584 |
| 5 | TRANSFERASE COMPLEX | 9 | 703 | 5.357e-05 | 0.006257 |
Over-represented Pathway
| Num | Pathway | Pathview | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|---|
| 1 | hsa04115_p53_signaling_pathway | 50 | 69 | 1.328e-134 | 2.391e-132 | |
| 2 | hsa04110_Cell_cycle | 18 | 128 | 1.425e-27 | 1.283e-25 | |
| 3 | hsa04210_Apoptosis | 10 | 89 | 1.606e-14 | 9.638e-13 | |
| 4 | hsa04151_PI3K_AKT_signaling_pathway | 14 | 351 | 1.077e-13 | 4.844e-12 | |
| 5 | hsa04114_Oocyte_meiosis | 5 | 114 | 9.512e-06 | 0.0003424 | |
| 6 | hsa04010_MAPK_signaling_pathway | 6 | 268 | 5.305e-05 | 0.001592 | |
| 7 | hsa04914_Progesterone.mediated_oocyte_maturation | 4 | 87 | 6.603e-05 | 0.001698 | |
| 8 | hsa04510_Focal_adhesion | 5 | 200 | 0.0001398 | 0.003146 | |
| 9 | hsa04650_Natural_killer_cell_mediated_cytotoxicity | 4 | 136 | 0.0003696 | 0.007393 | |
| 10 | hsa04310_Wnt_signaling_pathway | 4 | 151 | 0.000549 | 0.009673 | |
| 11 | hsa04390_Hippo_signaling_pathway | 4 | 154 | 0.0005911 | 0.009673 | |
| 12 | hsa04722_Neurotrophin_signaling_pathway | 3 | 127 | 0.003943 | 0.05914 | |
| 13 | hsa04120_Ubiquitin_mediated_proteolysis | 3 | 139 | 0.005072 | 0.07023 | |
| 14 | hsa00480_Glutathione_metabolism | 2 | 50 | 0.00695 | 0.08936 | |
| 15 | hsa00240_Pyrimidine_metabolism | 2 | 99 | 0.02547 | 0.3056 | |
| 16 | hsa04530_Tight_junction | 2 | 133 | 0.04369 | 0.4915 | |
| 17 | hsa04630_Jak.STAT_signaling_pathway | 2 | 155 | 0.0574 | 0.6077 | |
| 18 | hsa00230_Purine_metabolism | 2 | 162 | 0.06204 | 0.6204 |
lncRNA-mediated sponge
| Num | lncRNA | miRNAs | miRNAs count | Gene | Sponge regulatory network | lncRNA log2FC | lncRNA pvalue | Gene log2FC | Gene pvalue | lncRNA-gene Pearson correlation |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | LINC00689 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-495-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 16 | CASP9 | Sponge network | 0.116 | 0.68016 | -0.19 | 0.00861 | 0.618 |
| 2 | AC074286.1 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-324-5p;hsa-miR-339-5p;hsa-miR-500a-5p | 10 | ATM | Sponge network | 0.1 | 0.1736 | -0.045 | 0.43965 | 0.585 |
| 3 | LINC00174 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-3607-3p;hsa-miR-766-3p;hsa-miR-98-5p | 14 | MDM4 | Sponge network | 0.189 | 0.00899 | 0.065 | 0.34571 | 0.575 |
| 4 | RP5-1074L1.4 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p | 12 | MDM4 | Sponge network | 0.206 | 0.02654 | 0.065 | 0.34571 | 0.565 |
| 5 | LINC01004 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-7-1-3p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | 0.072 | 0.36263 | 0.065 | 0.34571 | 0.563 |
| 6 | RP11-54O7.3 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-495-3p | 13 | CASP9 | Sponge network | -0.583 | 0.0001 | -0.19 | 0.00861 | 0.56 |
| 7 | RP4-669L17.10 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-30d-3p;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-766-3p;hsa-miR-98-5p | 11 | MDM4 | Sponge network | 0.081 | 0.17237 | 0.065 | 0.34571 | 0.557 |
| 8 | PAXBP1-AS1 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-664a-3p | 10 | CCNG2 | Sponge network | -0.141 | 0.01015 | -0.12 | 0.03505 | 0.555 |
| 9 | RP11-458F8.4 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-98-5p | 13 | MDM4 | Sponge network | 0.222 | 0.00295 | 0.065 | 0.34571 | 0.542 |
| 10 | RP11-504P24.8 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-7-1-3p;hsa-miR-98-5p | 12 | MDM4 | Sponge network | 0.008 | 0.9184 | 0.065 | 0.34571 | 0.539 |
| 11 | GABPB1-AS1 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-339-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 11 | ATM | Sponge network | 0.035 | 0.63256 | -0.045 | 0.43965 | 0.537 |
| 12 | RP11-54O7.1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-424-5p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.181 | 0.33352 | -0.19 | 0.00861 | 0.534 |
| 13 | RP11-159D12.2 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 16 | MDM4 | Sponge network | 0.049 | 0.56968 | 0.065 | 0.34571 | 0.534 |
| 14 | PDXDC2P |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-491-5p;hsa-miR-766-3p;hsa-miR-98-5p | 14 | MDM4 | Sponge network | 0.013 | 0.86436 | 0.065 | 0.34571 | 0.524 |
| 15 | RP11-486G15.2 | hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | 0.213 | 0.00859 | 0.065 | 0.34571 | 0.515 |
| 16 | TPT1-AS1 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-26b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-324-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 10 | ATM | Sponge network | 0.004 | 0.91695 | -0.045 | 0.43965 | 0.514 |
| 17 | LINC00926 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-491-5p;hsa-miR-766-3p | 13 | MDM4 | Sponge network | 0.229 | 0.00656 | 0.065 | 0.34571 | 0.514 |
| 18 | RAD51-AS1 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-3607-3p;hsa-miR-766-3p | 10 | MDM4 | Sponge network | -0.108 | 0.12313 | 0.065 | 0.34571 | 0.512 |
| 19 | AC004158.3 |
hsa-let-7a-2-3p;hsa-miR-135a-5p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-664a-3p | 10 | CCNG2 | Sponge network | -0.189 | 0.03376 | -0.12 | 0.03505 | 0.512 |
| 20 | RP11-314B1.2 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-664a-3p;hsa-miR-93-5p | 12 | CCNG2 | Sponge network | -0.91 | 1.0E-5 | -0.12 | 0.03505 | 0.51 |
| 21 | SNHG16 |
hsa-let-7e-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-425-5p;hsa-miR-495-3p;hsa-miR-7-1-3p;hsa-miR-769-3p;hsa-miR-885-5p | 12 | CCND1 | Sponge network | 0.251 | 0 | 0.517 | 0 | 0.508 |
| 22 | ZNF571-AS1 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-339-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 11 | ATM | Sponge network | -0.06 | 0.50289 | -0.045 | 0.43965 | 0.499 |
| 23 | AC005154.6 |
hsa-miR-107;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 14 | MDM4 | Sponge network | 0.116 | 0.09943 | 0.065 | 0.34571 | 0.499 |
| 24 | LINC00925 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-339-5p;hsa-miR-766-3p | 11 | ATM | Sponge network | -0.477 | 0.00023 | -0.045 | 0.43965 | 0.498 |
| 25 | KB-1572G7.2 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-766-3p | 15 | MDM4 | Sponge network | 0.005 | 0.94044 | 0.065 | 0.34571 | 0.494 |
| 26 | GUSBP11 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-766-3p | 15 | MDM4 | Sponge network | -0.018 | 0.79043 | 0.065 | 0.34571 | 0.492 |
| 27 | SNHG12 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-326;hsa-miR-488-3p;hsa-miR-7-1-3p;hsa-miR-766-3p | 12 | MDM4 | Sponge network | 0.225 | 0.00271 | 0.065 | 0.34571 | 0.491 |
| 28 | RP11-401P9.4 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-495-3p | 10 | CASP9 | Sponge network | -0.21 | 0.0503 | -0.19 | 0.00861 | 0.489 |
| 29 | CAPN10-AS1 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p | 13 | MDM4 | Sponge network | 0.169 | 0.03539 | 0.065 | 0.34571 | 0.476 |
| 30 | MALAT1 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p | 15 | MDM4 | Sponge network | -0.03 | 0.71332 | 0.065 | 0.34571 | 0.474 |
| 31 | RP11-336K24.12 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-488-3p | 11 | MDM4 | Sponge network | 0.017 | 0.86449 | 0.065 | 0.34571 | 0.473 |
| 32 | AC074117.10 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-326;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 15 | MDM4 | Sponge network | 0.236 | 9.0E-5 | 0.065 | 0.34571 | 0.473 |
| 33 | RP11-337C18.8 | hsa-let-7a-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-374a-3p;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-93-5p | 12 | ZMAT3 | Sponge network | -0.06 | 0.28887 | 0.025 | 0.76977 | 0.472 |
| 34 | RP11-161M6.2 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p | 11 | CASP9 | Sponge network | -0.447 | 0.00099 | -0.19 | 0.00861 | 0.47 |
| 35 | NNT-AS1 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-324-5p;hsa-miR-339-5p | 10 | ATM | Sponge network | -0.042 | 0.32273 | -0.045 | 0.43965 | 0.466 |
| 36 | SNAP25-AS1 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-374a-3p;hsa-miR-421;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-93-5p | 18 | ZMAT3 | Sponge network | -0.486 | 0.00121 | 0.025 | 0.76977 | 0.462 |
| 37 | RP11-1055B8.4 | hsa-let-7b-5p;hsa-miR-107;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-766-3p | 10 | MDM4 | Sponge network | -0.202 | 0.08988 | 0.065 | 0.34571 | 0.461 |
| 38 | WDR11-AS1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-450b-5p | 12 | CASP9 | Sponge network | -0.487 | 0.00014 | -0.19 | 0.00861 | 0.457 |
| 39 | HCG18 | hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-374a-3p;hsa-miR-425-5p;hsa-miR-576-5p;hsa-miR-590-3p | 11 | ZMAT3 | Sponge network | 0.069 | 0.15433 | 0.025 | 0.76977 | 0.456 |
| 40 | LINC00928 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p | 10 | CASP9 | Sponge network | -0.179 | 0.18179 | -0.19 | 0.00861 | 0.455 |
| 41 | LINC00906 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-450b-5p;hsa-miR-590-3p | 13 | CASP9 | Sponge network | -0.618 | 0.00636 | -0.19 | 0.00861 | 0.454 |
| 42 | MIR17HG |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-3607-3p;hsa-miR-7-1-3p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | -0.011 | 0.91286 | 0.065 | 0.34571 | 0.452 |
| 43 | AC021224.1 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-34a-5p;hsa-miR-425-5p;hsa-miR-495-3p | 10 | CCND1 | Sponge network | 0.014 | 0.82698 | 0.517 | 0 | 0.451 |
| 44 | RP11-250B2.5 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 10 | MDM4 | Sponge network | -0.201 | 0.03654 | 0.065 | 0.34571 | 0.449 |
| 45 | LINC00925 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-495-3p;hsa-miR-548b-3p | 13 | CASP9 | Sponge network | -0.477 | 0.00023 | -0.19 | 0.00861 | 0.448 |
| 46 | AC004158.3 |
hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-374a-3p;hsa-miR-576-5p;hsa-miR-590-3p | 11 | ZMAT3 | Sponge network | -0.189 | 0.03376 | 0.025 | 0.76977 | 0.447 |
| 47 | RP11-600F24.7 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 11 | ATM | Sponge network | -0.056 | 0.36408 | -0.045 | 0.43965 | 0.446 |
| 48 | CTB-92J24.2 |
hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-129-5p;hsa-miR-145-5p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p | 18 | CCND2 | Sponge network | 0.263 | 0.00305 | 0.278 | 0.00231 | 0.445 |
| 49 | LINC00511 |
hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-150-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-30d-5p;hsa-miR-324-5p;hsa-miR-34a-5p;hsa-miR-380-5p;hsa-miR-381-3p;hsa-miR-421;hsa-miR-491-5p | 12 | TP53 | Sponge network | 0.049 | 0.52794 | 0.346 | 1.0E-5 | 0.444 |
| 50 | RP11-480A16.1 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-488-3p;hsa-miR-7-1-3p;hsa-miR-766-3p | 13 | MDM4 | Sponge network | -0.026 | 0.76579 | 0.065 | 0.34571 | 0.444 |
| 51 | RAMP2-AS1 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-339-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 11 | ATM | Sponge network | -0.1 | 0.31823 | -0.045 | 0.43965 | 0.443 |
| 52 | SERHL |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-3607-3p;hsa-miR-491-5p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | -0.183 | 0.068 | 0.065 | 0.34571 | 0.442 |
| 53 | RP5-1159O4.2 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-7-1-3p | 10 | MDM4 | Sponge network | -0.185 | 0.04861 | 0.065 | 0.34571 | 0.442 |
| 54 | RP11-37B2.1 |
hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-495-3p | 10 | CASP9 | Sponge network | -0.012 | 0.80744 | -0.19 | 0.00861 | 0.441 |
| 55 | GAS5 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-365a-3p;hsa-miR-425-5p;hsa-miR-495-3p;hsa-miR-7-1-3p | 12 | CCND1 | Sponge network | 0.059 | 0.40224 | 0.517 | 0 | 0.44 |
| 56 | LINC00599 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-320c;hsa-miR-576-5p;hsa-miR-590-5p;hsa-miR-664a-3p;hsa-miR-93-5p | 10 | CCNG2 | Sponge network | -0.887 | 0 | -0.12 | 0.03505 | 0.436 |
| 57 | RP11-334C17.5 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-766-3p;hsa-miR-98-5p | 13 | MDM4 | Sponge network | -0.007 | 0.95213 | 0.065 | 0.34571 | 0.433 |
| 58 | LINC00652 |
hsa-let-7a-2-3p;hsa-miR-135a-5p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p | 10 | CCNG2 | Sponge network | 0.093 | 0.33929 | -0.12 | 0.03505 | 0.433 |
| 59 | LINC00969 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-148b-3p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-766-3p;hsa-miR-98-5p | 14 | MDM4 | Sponge network | 0.102 | 0.15914 | 0.065 | 0.34571 | 0.429 |
| 60 | CPB2-AS1 |
hsa-let-7a-2-3p;hsa-miR-135a-5p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-708-3p;hsa-miR-93-5p | 12 | CCNG2 | Sponge network | -0.169 | 0.03939 | -0.12 | 0.03505 | 0.423 |
| 61 | RFPL1S |
hsa-let-7a-2-3p;hsa-miR-135a-5p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-320c;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-93-5p | 11 | CCNG2 | Sponge network | -0.457 | 0.11358 | -0.12 | 0.03505 | 0.421 |
| 62 | LINC00237 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-135a-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-3065-5p;hsa-miR-425-5p;hsa-miR-769-3p | 12 | CCND1 | Sponge network | -0.151 | 0.23651 | 0.517 | 0 | 0.418 |
| 63 | RP11-359E3.4 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 11 | ATM | Sponge network | -0.139 | 0.0251 | -0.045 | 0.43965 | 0.417 |
| 64 | NDUFA6-AS1 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-320c;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-664a-3p;hsa-miR-93-5p | 10 | CCNG2 | Sponge network | -0.325 | 0 | -0.12 | 0.03505 | 0.417 |
| 65 | DNAJC3-AS1 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-664a-3p;hsa-miR-708-3p;hsa-miR-93-5p | 11 | CCNG2 | Sponge network | -0.171 | 0.00435 | -0.12 | 0.03505 | 0.412 |
| 66 | LINC00173 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-7-1-3p;hsa-miR-766-3p | 10 | MDM4 | Sponge network | -0.153 | 0.12107 | 0.065 | 0.34571 | 0.411 |
| 67 | FAM66C |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p | 10 | CCNG2 | Sponge network | -0.164 | 0.00925 | -0.12 | 0.03505 | 0.409 |
| 68 | RP11-133K1.6 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-338-3p;hsa-miR-490-3p;hsa-miR-7-1-3p;hsa-miR-769-3p | 13 | CCND1 | Sponge network | 0.235 | 0.00273 | 0.517 | 0 | 0.408 |
| 69 | RP11-981G7.6 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 17 | MDM4 | Sponge network | -0.172 | 0.0483 | 0.065 | 0.34571 | 0.403 |
| 70 | LINC00472 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-374a-3p;hsa-miR-374b-5p;hsa-miR-421;hsa-miR-423-5p;hsa-miR-425-5p;hsa-miR-93-5p | 16 | ZMAT3 | Sponge network | -0.055 | 0.48251 | 0.025 | 0.76977 | 0.403 |
| 71 | SNAP25-AS1 |
hsa-let-7a-2-3p;hsa-miR-135a-5p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-320c;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-93-5p | 11 | CCNG2 | Sponge network | -0.486 | 0.00121 | -0.12 | 0.03505 | 0.402 |
| 72 | RP11-499P20.2 | hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p | 10 | CASP9 | Sponge network | -0.103 | 0.23872 | -0.19 | 0.00861 | 0.401 |
| 73 | XXbac-BPGBPG55C20.2 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.162 | 0.02919 | -0.19 | 0.00861 | 0.397 |
| 74 | LINC00693 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-495-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 15 | CASP9 | Sponge network | -0.302 | 0.00059 | -0.19 | 0.00861 | 0.394 |
| 75 | RP11-498C9.15 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-488-3p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | 0.081 | 0.19533 | 0.065 | 0.34571 | 0.391 |
| 76 | COX10-AS1 |
hsa-let-7g-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-150-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30e-3p;hsa-miR-324-3p;hsa-miR-488-3p;hsa-miR-660-5p;hsa-miR-7-1-3p | 17 | CCND2 | Sponge network | 0.22 | 0 | 0.278 | 0.00231 | 0.39 |
| 77 | RP11-728F11.4 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-495-3p;hsa-miR-548b-3p | 13 | CASP9 | Sponge network | -0.285 | 0.03797 | -0.19 | 0.00861 | 0.387 |
| 78 | FAM66C |
hsa-let-7a-3p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-425-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p | 14 | ZMAT3 | Sponge network | -0.164 | 0.00925 | 0.025 | 0.76977 | 0.386 |
| 79 | GABPB1-AS1 |
hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 17 | MDM4 | Sponge network | 0.035 | 0.63256 | 0.065 | 0.34571 | 0.385 |
| 80 | LINC00910 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-26b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-339-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 10 | ATM | Sponge network | -0.045 | 0.47068 | -0.045 | 0.43965 | 0.384 |
| 81 | RP11-401P9.5 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.369 | 0.02276 | -0.19 | 0.00861 | 0.384 |
| 82 | RP11-725P16.2 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-495-3p | 10 | CASP9 | Sponge network | 0.044 | 0.74072 | -0.19 | 0.00861 | 0.381 |
| 83 | TUG1 |
hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-374a-3p;hsa-miR-421;hsa-miR-425-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p | 12 | ZMAT3 | Sponge network | 0.012 | 0.80383 | 0.025 | 0.76977 | 0.381 |
| 84 | SOX21-AS1 |
hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-424-5p;hsa-miR-495-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 13 | CASP9 | Sponge network | -0.021 | 0.7487 | -0.19 | 0.00861 | 0.38 |
| 85 | PAXBP1-AS1 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-421;hsa-miR-425-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p | 14 | ZMAT3 | Sponge network | -0.141 | 0.01015 | 0.025 | 0.76977 | 0.379 |
| 86 | RFPL1S |
hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-421;hsa-miR-454-3p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-93-5p | 14 | ZMAT3 | Sponge network | -0.457 | 0.11358 | 0.025 | 0.76977 | 0.378 |
| 87 | PWAR6 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-28-5p;hsa-miR-320c;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-664a-3p;hsa-miR-93-5p | 10 | CCNG2 | Sponge network | -0.579 | 0 | -0.12 | 0.03505 | 0.376 |
| 88 | AE000661.37 | hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-186-5p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-421;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p | 10 | ZMAT3 | Sponge network | 0.185 | 0.45383 | 0.025 | 0.76977 | 0.374 |
| 89 | GABPB1-AS1 |
hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-150-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-30d-5p;hsa-miR-34a-5p;hsa-miR-421;hsa-miR-491-5p;hsa-miR-504-5p | 10 | TP53 | Sponge network | 0.035 | 0.63256 | 0.346 | 1.0E-5 | 0.374 |
| 90 | LINC00698 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p | 10 | CASP9 | Sponge network | -0.429 | 0.13072 | -0.19 | 0.00861 | 0.373 |
| 91 | RP11-305E6.4 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-590-3p | 10 | CASP9 | Sponge network | -0.195 | 0.00323 | -0.19 | 0.00861 | 0.371 |
| 92 | DLGAP1-AS2 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p | 10 | MDM4 | Sponge network | 0.41 | 3.0E-5 | 0.065 | 0.34571 | 0.369 |
| 93 | RP11-677M14.7 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-425-5p;hsa-miR-454-3p;hsa-miR-590-5p;hsa-miR-93-5p | 15 | ZMAT3 | Sponge network | -0.187 | 0.03426 | 0.025 | 0.76977 | 0.368 |
| 94 | RP11-645C24.5 |
hsa-let-7b-5p;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-29a-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-766-3p;hsa-miR-98-5p | 11 | MDM4 | Sponge network | -0.127 | 0.20944 | 0.065 | 0.34571 | 0.366 |
| 95 | CBR3-AS1 |
hsa-let-7a-2-3p;hsa-miR-135a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p | 10 | CCNG2 | Sponge network | 0.161 | 0.01099 | -0.12 | 0.03505 | 0.366 |
| 96 | RBM26-AS1 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-19b-3p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-374b-5p;hsa-miR-425-5p;hsa-miR-590-3p | 11 | ZMAT3 | Sponge network | -0.133 | 0.04018 | 0.025 | 0.76977 | 0.365 |
| 97 | RP5-1068E13.7 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-326;hsa-miR-488-3p;hsa-miR-98-5p | 10 | MDM4 | Sponge network | -0.04 | 0.61696 | 0.065 | 0.34571 | 0.364 |
| 98 | ZFAS1 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-425-5p;hsa-miR-495-3p;hsa-miR-7-1-3p | 11 | CCND1 | Sponge network | 0.007 | 0.91637 | 0.517 | 0 | 0.362 |
| 99 | AC097724.3 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-590-3p | 10 | CASP9 | Sponge network | -0.319 | 0.00142 | -0.19 | 0.00861 | 0.362 |
| 100 | GAS5 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-495-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 12 | CASP9 | Sponge network | 0.059 | 0.40224 | -0.19 | 0.00861 | 0.361 |
| 101 | RP11-355O1.11 |
hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-491-5p;hsa-miR-7-1-3p | 10 | MDM4 | Sponge network | 0.059 | 0.33222 | 0.065 | 0.34571 | 0.359 |
| 102 | RP11-448A19.1 |
hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 13 | MDM4 | Sponge network | 0.035 | 0.53357 | 0.065 | 0.34571 | 0.357 |
| 103 | NNT-AS1 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-374a-3p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-421;hsa-miR-425-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-708-3p;hsa-miR-93-5p | 16 | ZMAT3 | Sponge network | -0.042 | 0.32273 | 0.025 | 0.76977 | 0.356 |
| 104 | LINC00680 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 10 | CASP9 | Sponge network | 0.059 | 0.41284 | -0.19 | 0.00861 | 0.355 |
| 105 | RP11-488C13.5 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-590-3p | 10 | CASP9 | Sponge network | -0.249 | 2.0E-5 | -0.19 | 0.00861 | 0.355 |
| 106 | LINC00960 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-548b-3p;hsa-miR-590-3p | 13 | CASP9 | Sponge network | -0.005 | 0.96517 | -0.19 | 0.00861 | 0.354 |
| 107 | RP5-1092A3.4 | hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-766-3p | 11 | MDM4 | Sponge network | 0.376 | 0.00079 | 0.065 | 0.34571 | 0.352 |
| 108 | AC005562.1 |
hsa-let-7e-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-338-3p;hsa-miR-425-5p;hsa-miR-7-1-3p;hsa-miR-769-3p;hsa-miR-885-5p | 11 | CCND1 | Sponge network | 0.152 | 0.0006 | 0.517 | 0 | 0.351 |
| 109 | PAXIP1-AS1 |
hsa-miR-107;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | 0.045 | 0.36627 | 0.065 | 0.34571 | 0.35 |
| 110 | MIAT |
hsa-let-7a-2-3p;hsa-miR-135a-5p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-320c;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-708-3p | 10 | CCNG2 | Sponge network | -0.231 | 0.09535 | -0.12 | 0.03505 | 0.35 |
| 111 | TTC28-AS1 |
hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 10 | MDM4 | Sponge network | -0.079 | 0.07631 | 0.065 | 0.34571 | 0.349 |
| 112 | RP11-133K1.6 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-548b-3p;hsa-miR-590-3p | 12 | CASP9 | Sponge network | 0.235 | 0.00273 | -0.19 | 0.00861 | 0.345 |
| 113 | RNF219-AS1 | hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-548b-3p | 11 | CASP9 | Sponge network | -1.144 | 0 | -0.19 | 0.00861 | 0.345 |
| 114 | AC074286.1 |
hsa-let-7a-3p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-374b-5p;hsa-miR-421;hsa-miR-425-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-708-3p | 12 | ZMAT3 | Sponge network | 0.1 | 0.1736 | 0.025 | 0.76977 | 0.345 |
| 115 | RP11-441O15.3 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-3607-3p;hsa-miR-7-1-3p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | -0.238 | 0.00537 | 0.065 | 0.34571 | 0.342 |
| 116 | AC004158.3 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-324-5p;hsa-miR-500a-5p | 11 | ATM | Sponge network | -0.189 | 0.03376 | -0.045 | 0.43965 | 0.341 |
| 117 | RP11-429J17.2 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p | 11 | CASP9 | Sponge network | -0.107 | 0.12698 | -0.19 | 0.00861 | 0.34 |
| 118 | CTD-2228K2.7 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-488-3p;hsa-miR-766-3p;hsa-miR-98-5p | 10 | MDM4 | Sponge network | -0.1 | 0.22791 | 0.065 | 0.34571 | 0.34 |
| 119 | TTC28-AS1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-548b-3p;hsa-miR-590-3p | 12 | CASP9 | Sponge network | -0.079 | 0.07631 | -0.19 | 0.00861 | 0.339 |
| 120 | LINC00863 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-324-5p;hsa-miR-339-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 13 | ATM | Sponge network | -0.074 | 0.22385 | -0.045 | 0.43965 | 0.339 |
| 121 | INHBA-AS1 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-374a-3p;hsa-miR-374a-5p;hsa-miR-421;hsa-miR-590-3p;hsa-miR-93-5p | 16 | ZMAT3 | Sponge network | -1.228 | 0 | 0.025 | 0.76977 | 0.338 |
| 122 | LINC00461 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-339-5p;hsa-miR-766-3p | 11 | ATM | Sponge network | -0.125 | 0.18585 | -0.045 | 0.43965 | 0.338 |
| 123 | DNAJC27-AS1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-548b-3p | 11 | CASP9 | Sponge network | -0.358 | 0 | -0.19 | 0.00861 | 0.337 |
| 124 | H1FX-AS1 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-491-5p | 12 | MDM4 | Sponge network | 0.049 | 0.49494 | 0.065 | 0.34571 | 0.336 |
| 125 | GDNF-AS1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-495-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 13 | CASP9 | Sponge network | -0.445 | 0.02696 | -0.19 | 0.00861 | 0.336 |
| 126 | CTD-2366F13.1 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-423-5p;hsa-miR-425-5p;hsa-miR-590-3p;hsa-miR-93-5p | 16 | ZMAT3 | Sponge network | -0.166 | 0.00433 | 0.025 | 0.76977 | 0.335 |
| 127 | RP11-588G21.2 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-135a-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-3065-5p;hsa-miR-330-3p;hsa-miR-34a-5p;hsa-miR-425-5p;hsa-miR-7-1-3p;hsa-miR-769-3p | 12 | CCND1 | Sponge network | -0.336 | 0.02103 | 0.517 | 0 | 0.332 |
| 128 | RP11-498C9.15 |
hsa-let-7b-3p;hsa-let-7g-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-26a-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29c-3p;hsa-miR-488-3p | 12 | CCND2 | Sponge network | 0.081 | 0.19533 | 0.278 | 0.00231 | 0.331 |
| 129 | EPB41L4A-AS1 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-320c;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-664a-3p;hsa-miR-93-5p | 12 | CCNG2 | Sponge network | -0.184 | 0.00882 | -0.12 | 0.03505 | 0.331 |
| 130 | C20orf203 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p | 11 | CASP9 | Sponge network | -0.729 | 0 | -0.19 | 0.00861 | 0.33 |
| 131 | AC005562.1 |
hsa-miR-140-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30a-5p;hsa-miR-30b-5p;hsa-miR-30d-5p;hsa-miR-338-3p;hsa-miR-362-5p;hsa-miR-488-5p;hsa-miR-7-1-3p;hsa-miR-885-5p | 12 | CDK6 | Sponge network | 0.152 | 0.0006 | 0.515 | 1.0E-5 | 0.33 |
| 132 | AC073283.4 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-495-3p | 12 | CASP9 | Sponge network | -0.116 | 0.25631 | -0.19 | 0.00861 | 0.33 |
| 133 | RP11-588G21.2 |
hsa-let-7a-2-3p;hsa-miR-135a-5p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-664a-3p;hsa-miR-93-5p | 13 | CCNG2 | Sponge network | -0.336 | 0.02103 | -0.12 | 0.03505 | 0.33 |
| 134 | SNHG1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-495-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 12 | CASP9 | Sponge network | 0 | 0.99893 | -0.19 | 0.00861 | 0.329 |
| 135 | RP11-77P6.2 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-491-5p;hsa-miR-7-1-3p | 10 | MDM4 | Sponge network | -0.196 | 0.01608 | 0.065 | 0.34571 | 0.329 |
| 136 | LINC00511 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-135a-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-34a-5p;hsa-miR-365a-3p;hsa-miR-495-3p;hsa-miR-7-1-3p;hsa-miR-769-3p | 15 | CCND1 | Sponge network | 0.049 | 0.52794 | 0.517 | 0 | 0.329 |
| 137 | GABPB1-AS1 |
hsa-let-7e-5p;hsa-let-7g-5p;hsa-miR-100-5p;hsa-miR-125a-5p;hsa-miR-26a-5p;hsa-miR-30a-5p;hsa-miR-30c-5p;hsa-miR-342-3p;hsa-miR-421;hsa-miR-484 | 10 | RRM2 | Sponge network | 0.035 | 0.63256 | 1.73 | 0 | 0.327 |
| 138 | DGCR5 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-320c;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-708-3p | 10 | CCNG2 | Sponge network | -0.472 | 0 | -0.12 | 0.03505 | 0.326 |
| 139 | RP11-277P12.20 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 12 | CASP9 | Sponge network | 0.021 | 0.86605 | -0.19 | 0.00861 | 0.325 |
| 140 | RP11-461O7.1 | hsa-let-7a-3p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-362-5p;hsa-miR-423-5p;hsa-miR-590-3p | 12 | ZMAT3 | Sponge network | -0.054 | 0.46449 | 0.025 | 0.76977 | 0.323 |
| 141 | ZFAS1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-495-3p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | 0.007 | 0.91637 | -0.19 | 0.00861 | 0.323 |
| 142 | COX10-AS1 |
hsa-let-7e-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-34a-5p;hsa-miR-365a-3p;hsa-miR-7-1-3p;hsa-miR-769-3p;hsa-miR-885-5p | 12 | CCND1 | Sponge network | 0.22 | 0 | 0.517 | 0 | 0.321 |
| 143 | RP11-966I7.2 | hsa-let-7a-3p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-374a-3p;hsa-miR-421;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p | 11 | ZMAT3 | Sponge network | 0.044 | 0.87432 | 0.025 | 0.76977 | 0.318 |
| 144 | RP11-119F7.5 |
hsa-let-7b-5p;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-7-1-3p | 10 | MDM4 | Sponge network | -0.237 | 0.00026 | 0.065 | 0.34571 | 0.317 |
| 145 | DLEU2 |
hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-148b-3p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | 0.314 | 1.0E-5 | 0.065 | 0.34571 | 0.317 |
| 146 | RP11-259K5.1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-548b-3p | 11 | CASP9 | Sponge network | -0.323 | 0.01935 | -0.19 | 0.00861 | 0.314 |
| 147 | XXbac-BPG308K3.6 |
hsa-let-7a-3p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-421;hsa-miR-576-5p;hsa-miR-590-3p | 11 | ZMAT3 | Sponge network | 0.364 | 0.1417 | 0.025 | 0.76977 | 0.313 |
| 148 | FAM95B1 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-326;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | 0.525 | 8.0E-5 | 0.065 | 0.34571 | 0.313 |
| 149 | RP11-374M1.2 |
hsa-miR-125a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-548b-3p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.246 | 0.00171 | -0.19 | 0.00861 | 0.313 |
| 150 | ZEB1-AS1 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-365a-3p;hsa-miR-425-5p | 11 | CCND1 | Sponge network | -0.131 | 0.09936 | 0.517 | 0 | 0.312 |
| 151 | LIFR-AS1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-424-5p | 10 | CASP9 | Sponge network | -0.298 | 0 | -0.19 | 0.00861 | 0.312 |
| 152 | RP1-104O17.1 | hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-425-5p;hsa-miR-590-5p | 13 | ZMAT3 | Sponge network | -0.272 | 0.0126 | 0.025 | 0.76977 | 0.311 |
| 153 | RP11-359E3.4 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-424-5p;hsa-miR-495-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 13 | CASP9 | Sponge network | -0.139 | 0.0251 | -0.19 | 0.00861 | 0.31 |
| 154 | SERHL |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-548b-3p | 12 | CASP9 | Sponge network | -0.183 | 0.068 | -0.19 | 0.00861 | 0.309 |
| 155 | TPT1-AS1 |
hsa-miR-107;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 14 | MDM4 | Sponge network | 0.004 | 0.91695 | 0.065 | 0.34571 | 0.309 |
| 156 | SNHG1 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-326;hsa-miR-488-3p;hsa-miR-7-1-3p;hsa-miR-766-3p | 13 | MDM4 | Sponge network | 0 | 0.99893 | 0.065 | 0.34571 | 0.309 |
| 157 | MYCNOS |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-590-3p | 10 | CASP9 | Sponge network | -0.198 | 0.09003 | -0.19 | 0.00861 | 0.308 |
| 158 | RP11-277P12.20 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-34a-5p;hsa-miR-7-1-3p | 10 | CCND1 | Sponge network | 0.021 | 0.86605 | 0.517 | 0 | 0.308 |
| 159 | RP11-600F24.7 |
hsa-miR-107;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 10 | MDM4 | Sponge network | -0.056 | 0.36408 | 0.065 | 0.34571 | 0.308 |
| 160 | SNHG1 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-495-3p;hsa-miR-7-1-3p | 11 | CCND1 | Sponge network | 0 | 0.99893 | 0.517 | 0 | 0.307 |
| 161 | RP11-475I24.3 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 10 | ATM | Sponge network | 0.142 | 0.12904 | -0.045 | 0.43965 | 0.307 |
| 162 | RGMB-AS1 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-3065-5p;hsa-miR-34a-5p;hsa-miR-495-3p;hsa-miR-7-1-3p;hsa-miR-769-3p;hsa-miR-885-5p | 14 | CCND1 | Sponge network | -0.029 | 0.75643 | 0.517 | 0 | 0.306 |
| 163 | RP11-401P9.4 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-365a-3p;hsa-miR-425-5p;hsa-miR-495-3p;hsa-miR-769-3p;hsa-miR-885-5p | 13 | CCND1 | Sponge network | -0.21 | 0.0503 | 0.517 | 0 | 0.305 |
| 164 | CBR3-AS1 |
hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-421;hsa-miR-425-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p | 14 | ZMAT3 | Sponge network | 0.161 | 0.01099 | 0.025 | 0.76977 | 0.304 |
| 165 | RP11-483C6.1 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-135a-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-338-3p;hsa-miR-34a-5p;hsa-miR-425-5p;hsa-miR-495-3p;hsa-miR-885-5p | 15 | CCND1 | Sponge network | 0.276 | 0.03128 | 0.517 | 0 | 0.303 |
| 166 | RP11-262H14.4 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-135a-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-365a-3p;hsa-miR-425-5p;hsa-miR-495-3p;hsa-miR-7-1-3p;hsa-miR-769-3p | 11 | CCND1 | Sponge network | -0.011 | 0.89082 | 0.517 | 0 | 0.301 |
| 167 | LINC00511 |
hsa-let-7e-5p;hsa-let-7g-5p;hsa-miR-100-5p;hsa-miR-125a-5p;hsa-miR-26a-5p;hsa-miR-30a-5p;hsa-miR-30c-5p;hsa-miR-342-3p;hsa-miR-421;hsa-miR-484 | 10 | RRM2 | Sponge network | 0.049 | 0.52794 | 1.73 | 0 | 0.299 |
| 168 | CTB-55O6.12 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-30d-5p;hsa-miR-326;hsa-miR-491-5p;hsa-miR-766-3p | 10 | MDM4 | Sponge network | 0.02 | 0.79634 | 0.065 | 0.34571 | 0.298 |
| 169 | LINC00652 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-421;hsa-miR-576-5p;hsa-miR-590-3p | 13 | ZMAT3 | Sponge network | 0.093 | 0.33929 | 0.025 | 0.76977 | 0.297 |
| 170 | LINC00511 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-324-5p;hsa-miR-339-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 12 | ATM | Sponge network | 0.049 | 0.52794 | -0.045 | 0.43965 | 0.297 |
| 171 | AC021188.4 | hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-129-5p;hsa-miR-145-3p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-185-5p;hsa-miR-26b-5p;hsa-miR-29a-5p;hsa-miR-3622a-3p;hsa-miR-488-5p | 11 | CCND2 | Sponge network | 0.23 | 0.03087 | 0.278 | 0.00231 | 0.297 |
| 172 | CTB-31O20.2 | hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-324-3p;hsa-miR-488-3p | 19 | CCND2 | Sponge network | 0.102 | 0.10648 | 0.278 | 0.00231 | 0.296 |
| 173 | CPB2-AS1 |
hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-374a-3p;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-708-3p;hsa-miR-93-5p | 13 | ZMAT3 | Sponge network | -0.169 | 0.03939 | 0.025 | 0.76977 | 0.296 |
| 174 | LA16c-381G6.1 |
hsa-miR-125a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-590-3p | 10 | CASP9 | Sponge network | -0.682 | 0.05972 | -0.19 | 0.00861 | 0.296 |
| 175 | LINC00643 |
hsa-let-7a-3p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-374a-3p;hsa-miR-576-5p;hsa-miR-590-3p | 11 | ZMAT3 | Sponge network | -0.594 | 0.00279 | 0.025 | 0.76977 | 0.295 |
| 176 | RP5-1085F17.3 | hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-3607-3p;hsa-miR-488-3p | 11 | MDM4 | Sponge network | -0.041 | 0.56952 | 0.065 | 0.34571 | 0.294 |
| 177 | LINC01003 | hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-150-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-5p;hsa-miR-324-3p | 13 | CCND2 | Sponge network | 0.042 | 0.45455 | 0.278 | 0.00231 | 0.294 |
| 178 | TMEM254-AS1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-424-5p;hsa-miR-590-3p | 10 | CASP9 | Sponge network | -0.407 | 0 | -0.19 | 0.00861 | 0.293 |
| 179 | RP11-588G21.2 |
hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-374a-3p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-421;hsa-miR-425-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-5p | 16 | ZMAT3 | Sponge network | -0.336 | 0.02103 | 0.025 | 0.76977 | 0.293 |
| 180 | LINC00176 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-326;hsa-miR-488-3p;hsa-miR-491-5p;hsa-miR-766-3p | 11 | MDM4 | Sponge network | -0.314 | 0.02696 | 0.065 | 0.34571 | 0.292 |
| 181 | LINC00461 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-320c;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-664a-3p | 12 | CCNG2 | Sponge network | -0.125 | 0.18585 | -0.12 | 0.03505 | 0.291 |
| 182 | TMCC1-AS1 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-34a-5p;hsa-miR-365a-3p;hsa-miR-7-1-3p;hsa-miR-769-3p;hsa-miR-885-5p | 13 | CCND1 | Sponge network | -0.106 | 0.11207 | 0.517 | 0 | 0.291 |
| 183 | RP1-140K8.5 |
hsa-miR-1179;hsa-miR-1224-5p;hsa-miR-129-5p;hsa-miR-137;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-338-3p;hsa-miR-362-5p;hsa-miR-488-5p;hsa-miR-7-1-3p;hsa-miR-885-5p;hsa-miR-935 | 13 | CDK6 | Sponge network | 0.994 | 0 | 0.515 | 1.0E-5 | 0.291 |
| 184 | RP11-212P7.2 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.105 | 0.08007 | -0.19 | 0.00861 | 0.291 |
| 185 | RP11-329B9.5 | hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-495-3p | 11 | CASP9 | Sponge network | -0.182 | 0.02787 | -0.19 | 0.00861 | 0.291 |
| 186 | RP3-508I15.9 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.098 | 0.09507 | -0.19 | 0.00861 | 0.288 |
| 187 | CD27-AS1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p | 10 | CASP9 | Sponge network | -0.186 | 0.0011 | -0.19 | 0.00861 | 0.287 |
| 188 | PAXIP1-AS1 |
hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-331-5p;hsa-miR-488-3p | 18 | CCND2 | Sponge network | 0.045 | 0.36627 | 0.278 | 0.00231 | 0.287 |
| 189 | AC074117.10 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-490-3p;hsa-miR-495-3p;hsa-miR-7-1-3p | 11 | CCND1 | Sponge network | 0.236 | 9.0E-5 | 0.517 | 0 | 0.286 |
| 190 | RP11-981G7.6 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.172 | 0.0483 | -0.19 | 0.00861 | 0.286 |
| 191 | RP11-166D19.1 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p | 11 | CASP9 | Sponge network | -0.073 | 0.23261 | -0.19 | 0.00861 | 0.285 |
| 192 | CTC-559E9.5 | hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30e-3p | 12 | CCND2 | Sponge network | -0.001 | 0.97704 | 0.278 | 0.00231 | 0.284 |
| 193 | AC069513.4 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-98-5p | 11 | MDM4 | Sponge network | 0.092 | 0.31741 | 0.065 | 0.34571 | 0.284 |
| 194 | RP11-565F19.2 | hsa-let-7b-3p;hsa-let-7g-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-331-5p | 10 | CCND2 | Sponge network | 0.269 | 0 | 0.278 | 0.00231 | 0.284 |
| 195 | RP3-518E13.2 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-590-3p | 10 | CASP9 | Sponge network | -0.804 | 2.0E-5 | -0.19 | 0.00861 | 0.283 |
| 196 | LINC00511 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-495-3p;hsa-miR-548b-3p;hsa-miR-590-3p | 14 | CASP9 | Sponge network | 0.049 | 0.52794 | -0.19 | 0.00861 | 0.283 |
| 197 | RP11-1094M14.11 | hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-5p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-191-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-488-5p | 12 | CCND2 | Sponge network | 0.034 | 0.46474 | 0.278 | 0.00231 | 0.283 |
| 198 | GDNF-AS1 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-34a-5p;hsa-miR-365a-3p;hsa-miR-425-5p;hsa-miR-495-3p;hsa-miR-7-1-3p | 14 | CCND1 | Sponge network | -0.445 | 0.02696 | 0.517 | 0 | 0.281 |
| 199 | RP11-806K15.1 |
hsa-let-7b-5p;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-488-3p;hsa-miR-766-3p | 10 | MDM4 | Sponge network | -0.347 | 0.05118 | 0.065 | 0.34571 | 0.279 |
| 200 | RP3-525N10.2 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-7-1-3p;hsa-miR-766-3p | 12 | MDM4 | Sponge network | -0.294 | 0.00632 | 0.065 | 0.34571 | 0.278 |
| 201 | RP4-669P10.16 | hsa-miR-125a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-548b-3p | 11 | CASP9 | Sponge network | -0.37 | 0 | -0.19 | 0.00861 | 0.277 |
| 202 | AC005562.1 |
hsa-let-7g-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30e-3p;hsa-miR-488-5p;hsa-miR-500a-5p;hsa-miR-501-5p;hsa-miR-7-1-3p | 18 | CCND2 | Sponge network | 0.152 | 0.0006 | 0.278 | 0.00231 | 0.277 |
| 203 | RP11-483C6.1 |
hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-129-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30e-3p;hsa-miR-33a-3p;hsa-miR-500a-5p;hsa-miR-501-5p | 22 | CCND2 | Sponge network | 0.276 | 0.03128 | 0.278 | 0.00231 | 0.275 |
| 204 | RP11-77P6.2 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-495-3p;hsa-miR-548b-3p | 12 | CASP9 | Sponge network | -0.196 | 0.01608 | -0.19 | 0.00861 | 0.275 |
| 205 | GABPB1-AS1 |
hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-3622a-3p;hsa-miR-488-3p;hsa-miR-488-5p;hsa-miR-500a-5p;hsa-miR-501-5p;hsa-miR-660-5p;hsa-miR-7-1-3p | 29 | CCND2 | Sponge network | 0.035 | 0.63256 | 0.278 | 0.00231 | 0.275 |
| 206 | RP11-115C21.2 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-7-1-3p;hsa-miR-769-3p | 10 | CCND1 | Sponge network | 0.083 | 0.076 | 0.517 | 0 | 0.275 |
| 207 | RP11-448A19.1 |
hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-3622a-3p;hsa-miR-488-3p;hsa-miR-500a-5p;hsa-miR-7-1-3p | 26 | CCND2 | Sponge network | 0.035 | 0.53357 | 0.278 | 0.00231 | 0.274 |
| 208 | RP11-143A12.3 | hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-186-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-3622a-3p;hsa-miR-500a-5p;hsa-miR-501-5p;hsa-miR-660-5p;hsa-miR-7-1-3p | 16 | CCND2 | Sponge network | 0.213 | 0.07213 | 0.278 | 0.00231 | 0.273 |
| 209 | RP11-705C15.3 |
hsa-miR-101-3p;hsa-miR-1179;hsa-miR-1224-5p;hsa-miR-129-5p;hsa-miR-137;hsa-miR-140-3p;hsa-miR-338-3p;hsa-miR-488-5p;hsa-miR-491-3p;hsa-miR-7-1-3p;hsa-miR-935 | 11 | CDK6 | Sponge network | 0.293 | 2.0E-5 | 0.515 | 1.0E-5 | 0.272 |
| 210 | RP11-545I5.3 | hsa-let-7a-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-362-5p;hsa-miR-423-5p;hsa-miR-576-5p;hsa-miR-93-5p | 10 | ZMAT3 | Sponge network | -0.215 | 0.01077 | 0.025 | 0.76977 | 0.272 |
| 211 | LINC00960 |
hsa-let-7g-5p;hsa-miR-124-3p;hsa-miR-125a-5p;hsa-miR-155-5p;hsa-miR-16-5p;hsa-miR-192-5p;hsa-miR-24-3p;hsa-miR-34a-5p;hsa-miR-365a-3p;hsa-miR-455-3p;hsa-miR-671-5p;hsa-miR-940 | 12 | CDKN2A | Sponge network | -0.005 | 0.96517 | 0.019 | 0.90392 | 0.271 |
| 212 | AC002429.5 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-548b-3p;hsa-miR-590-3p | 14 | CASP9 | Sponge network | -0.845 | 0 | -0.19 | 0.00861 | 0.271 |
| 213 | MIR17HG |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-3065-5p;hsa-miR-330-3p;hsa-miR-34a-5p;hsa-miR-365a-3p;hsa-miR-425-5p;hsa-miR-490-3p;hsa-miR-495-3p;hsa-miR-7-1-3p;hsa-miR-769-3p | 17 | CCND1 | Sponge network | -0.011 | 0.91286 | 0.517 | 0 | 0.271 |
| 214 | TMPO-AS1 |
hsa-let-7g-5p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-331-5p;hsa-miR-7-1-3p | 16 | CCND2 | Sponge network | 0.456 | 0 | 0.278 | 0.00231 | 0.27 |
| 215 | LINC00689 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30d-3p;hsa-miR-324-5p;hsa-miR-339-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 10 | ATM | Sponge network | 0.116 | 0.68016 | -0.045 | 0.43965 | 0.27 |
| 216 | LINC00237 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.151 | 0.23651 | -0.19 | 0.00861 | 0.27 |
| 217 | RP11-21L23.2 |
hsa-let-7g-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-3622a-3p;hsa-miR-488-3p;hsa-miR-7-1-3p | 21 | CCND2 | Sponge network | 0.266 | 0.004 | 0.278 | 0.00231 | 0.267 |
| 218 | FAM95B1 |
hsa-miR-101-3p;hsa-miR-1179;hsa-miR-1224-5p;hsa-miR-129-5p;hsa-miR-137;hsa-miR-140-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30a-5p;hsa-miR-362-5p;hsa-miR-7-1-3p | 12 | CDK6 | Sponge network | 0.525 | 8.0E-5 | 0.515 | 1.0E-5 | 0.266 |
| 219 | ZNF883 | hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-5p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-501-5p;hsa-miR-660-5p | 17 | CCND2 | Sponge network | 0.103 | 0.1278 | 0.278 | 0.00231 | 0.266 |
| 220 | RP11-35G9.3 |
hsa-let-7e-5p;hsa-miR-1266-5p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-34a-5p;hsa-miR-425-5p;hsa-miR-495-3p;hsa-miR-7-1-3p;hsa-miR-769-3p | 11 | CCND1 | Sponge network | 0.182 | 0.001 | 0.517 | 0 | 0.265 |
| 221 | AP000487.5 |
hsa-miR-107;hsa-miR-126-5p;hsa-miR-140-3p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-491-5p;hsa-miR-766-3p | 10 | MDM4 | Sponge network | -0.074 | 0.15373 | 0.065 | 0.34571 | 0.264 |
| 222 | RP11-477D19.2 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p | 11 | MDM4 | Sponge network | -0.143 | 0.02743 | 0.065 | 0.34571 | 0.264 |
| 223 | LINC00689 |
hsa-let-7g-5p;hsa-miR-124-3p;hsa-miR-125a-5p;hsa-miR-155-5p;hsa-miR-16-5p;hsa-miR-24-3p;hsa-miR-34a-5p;hsa-miR-455-3p;hsa-miR-671-5p;hsa-miR-940 | 10 | CDKN2A | Sponge network | 0.116 | 0.68016 | 0.019 | 0.90392 | 0.264 |
| 224 | RP11-338N10.1 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-766-3p | 10 | MDM4 | Sponge network | -0.309 | 0.01484 | 0.065 | 0.34571 | 0.263 |
| 225 | DICER1-AS1 |
hsa-let-7b-5p;hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-29a-5p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 10 | MDM4 | Sponge network | -0.353 | 0 | 0.065 | 0.34571 | 0.262 |
| 226 | CTD-2541J13.1 | hsa-let-7b-3p;hsa-let-7g-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-150-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-331-5p;hsa-miR-488-3p | 15 | CCND2 | Sponge network | 0.166 | 0.08607 | 0.278 | 0.00231 | 0.262 |
| 227 | RP11-452L6.1 | hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-33a-3p | 15 | CCND2 | Sponge network | 0.026 | 0.70784 | 0.278 | 0.00231 | 0.262 |
| 228 | LINC00511 |
hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-324-3p;hsa-miR-3622a-3p;hsa-miR-500a-5p;hsa-miR-7-1-3p | 24 | CCND2 | Sponge network | 0.049 | 0.52794 | 0.278 | 0.00231 | 0.261 |
| 229 | NDUFA6-AS1 |
hsa-miR-125a-3p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-424-5p;hsa-miR-548b-3p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.325 | 0 | -0.19 | 0.00861 | 0.26 |
| 230 | CTB-92J24.2 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-330-3p;hsa-miR-495-3p | 10 | CCND1 | Sponge network | 0.263 | 0.00305 | 0.517 | 0 | 0.26 |
| 231 | RP11-7F18.2 |
hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-3p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-5p;hsa-miR-500a-5p;hsa-miR-501-5p | 17 | CCND2 | Sponge network | -0.096 | 0.18723 | 0.278 | 0.00231 | 0.26 |
| 232 | XXbac-BPGBPG55C20.2 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-320c;hsa-miR-374a-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-664a-3p;hsa-miR-708-3p | 10 | CCNG2 | Sponge network | -0.162 | 0.02919 | -0.12 | 0.03505 | 0.259 |
| 233 | RP11-624M8.1 | hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-548b-3p;hsa-miR-590-3p | 12 | CASP9 | Sponge network | -0.751 | 0 | -0.19 | 0.00861 | 0.258 |
| 234 | RP11-401P9.5 |
hsa-miR-107;hsa-miR-125b-2-3p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-3607-3p;hsa-miR-7-1-3p;hsa-miR-766-3p;hsa-miR-98-5p | 14 | MDM4 | Sponge network | -0.369 | 0.02276 | 0.065 | 0.34571 | 0.258 |
| 235 | DNAJC3-AS1 |
hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-421;hsa-miR-425-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-708-3p;hsa-miR-93-5p | 15 | ZMAT3 | Sponge network | -0.171 | 0.00435 | 0.025 | 0.76977 | 0.258 |
| 236 | RP11-359B12.2 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-424-5p;hsa-miR-548b-3p;hsa-miR-590-3p | 11 | CASP9 | Sponge network | -0.354 | 0 | -0.19 | 0.00861 | 0.256 |
| 237 | CTD-2534I21.8 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-135a-5p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-34a-5p;hsa-miR-769-3p | 10 | CCND1 | Sponge network | -0.674 | 0.00776 | 0.517 | 0 | 0.256 |
| 238 | RP3-337H4.8 |
hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-29a-5p;hsa-miR-324-3p | 12 | CCND2 | Sponge network | 0.304 | 1.0E-5 | 0.278 | 0.00231 | 0.255 |
| 239 | RP11-7F18.2 |
hsa-let-7b-5p;hsa-miR-126-5p;hsa-miR-148b-3p;hsa-miR-150-5p;hsa-miR-192-5p;hsa-miR-29a-5p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-491-5p;hsa-miR-98-5p | 10 | MDM4 | Sponge network | -0.096 | 0.18723 | 0.065 | 0.34571 | 0.254 |
| 240 | RP11-212P7.2 |
hsa-let-7f-1-3p;hsa-let-7g-5p;hsa-let-7i-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-146b-3p;hsa-miR-150-5p;hsa-miR-151a-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-191-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-29a-5p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-3622a-3p;hsa-miR-7-1-3p | 21 | CCND2 | Sponge network | -0.105 | 0.08007 | 0.278 | 0.00231 | 0.254 |
| 241 | RP11-66N24.4 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-424-5p | 11 | CASP9 | Sponge network | -0.671 | 0 | -0.19 | 0.00861 | 0.254 |
| 242 | LINC00959 | hsa-let-7a-3p;hsa-miR-106b-5p;hsa-miR-148b-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-3065-5p;hsa-miR-576-5p | 12 | ZMAT3 | Sponge network | -0.255 | 3.0E-5 | 0.025 | 0.76977 | 0.253 |
| 243 | RP11-705C15.3 |
hsa-let-7g-5p;hsa-miR-129-5p;hsa-miR-145-3p;hsa-miR-145-5p;hsa-miR-150-5p;hsa-miR-185-5p;hsa-miR-191-5p;hsa-miR-488-3p;hsa-miR-488-5p;hsa-miR-7-1-3p | 10 | CCND2 | Sponge network | 0.293 | 2.0E-5 | 0.278 | 0.00231 | 0.253 |
| 244 | AC073283.4 |
hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-186-5p;hsa-miR-18a-5p;hsa-miR-26b-5p;hsa-miR-30b-5p;hsa-miR-30c-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-500a-5p;hsa-miR-766-3p | 11 | ATM | Sponge network | -0.116 | 0.25631 | -0.045 | 0.43965 | 0.252 |
| 245 | RP1-79C4.4 |
hsa-miR-125a-3p;hsa-miR-126-5p;hsa-miR-133a-3p;hsa-miR-140-5p;hsa-miR-16-5p;hsa-miR-193b-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-342-5p;hsa-miR-495-3p | 10 | CASP9 | Sponge network | -0.001 | 0.99745 | -0.19 | 0.00861 | 0.252 |
| 246 | RP11-731J8.2 |
hsa-let-7a-2-3p;hsa-miR-21-5p;hsa-miR-26b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-320c;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-5p | 11 | CCNG2 | Sponge network | -0.626 | 1.0E-5 | -0.12 | 0.03505 | 0.252 |
| 247 | LINC00925 |
hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-1266-5p;hsa-miR-23b-3p;hsa-miR-26b-5p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-34a-5p;hsa-miR-425-5p;hsa-miR-495-3p;hsa-miR-7-1-3p;hsa-miR-885-5p | 13 | CCND1 | Sponge network | -0.477 | 0.00023 | 0.517 | 0 | 0.251 |